Behavioral and molecular evidence for a feedback interaction between morphine and HIV-1 viral proteins

Journal of Neuroimmune Pharmacology

Volumn 7, Issue 2, 2012, Pages 332-340

  Chang, Sulie L ^a   Connaghan, Kaitlyn P ^a  

^a SETON HALL UNIVERSITY   (United States)

Author keywords

Behavior; Conditioned place preference; Cytokine; HIV 1 viral protein; Morphine; Mu opioid receptor

Indexed keywords

ANTIRETROVIRUS AGENT; CHEMOKINE; CYTOKINE; DELTA OPIATE RECEPTOR; GAG PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITOR; KAPPA OPIATE RECEPTOR; MORPHINE; MORPHINE SULFATE; MU OPIATE RECEPTOR; OPIATE DERIVATIVE; PLACEBO; RNA DIRECTED DNA POLYMERASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; VIRUS PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; NARCOTIC AGENT;

ANALGESIA; BEHAVIOR; BIOENGINEERING; CELL CULTURE; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG PROTEIN BINDING; FEEDBACK SYSTEM; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; INFECTION CONTROL; LEARNING; LEARNING DISORDER; MAZE TEST; MEDIATOR; MEMORY DISORDER; MOLECULAR BIOLOGY; MOLECULAR DOCKING; MORPHINE ADDICTION; MORRIS WATER MAZE TEST; NONHUMAN; PLACE PREFERENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; REVIEW; REWARD; TRANSGENIC ANIMAL; VIRUS LOAD; VIRUS REPLICATION; VIRUS STRAIN; ANIMAL; ANIMAL BEHAVIOR; BIOSYNTHESIS; DISEASE MODEL; DRUG EFFECT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; METABOLISM; MOUSE;

ANIMALS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; FEEDBACK, PHYSIOLOGICAL; HIV INFECTIONS; HIV-1; HUMAN IMMUNODEFICIENCY VIRUS PROTEINS; HUMANS; MICE; MORPHINE; MORPHINE DEPENDENCE; NARCOTICS; RECEPTORS, OPIOID, MU;

EID: 84859954561     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-011-9324-1     Document Type: Review

References (64)

1. HIV/AIDS Research and Education Are Crucial to Drug Abuse Prevention. NIDA Notes 20
2. Afonso VM, Eikelboom R (2003) Relationship between wheel running, feeding, drinking, and body weight in male rats. Physiol Behav 80(1):19-26 (Pubitemid 37249369)
3. Agbottah E, Zhang N, Dadgar S, Pumfery A, Wade JD, Zeng C, Kashanchi F (2006) Inhibition of HIV-1 virus replication using small soluble Tat peptides. Virology 345:373-389 (Pubitemid 43189897)
4. Avdoshina V, Biggio F, Palchik G, Campbell LA, Mocchetti I (2010) Morphine induces the release of CCL5 from astrocytes: potential neuroprotective mechanism against the HIV protein gp120. Glia 58:1630-1639. doi:10.1002/glia. 21035
5. Barak O, Goshen I, Ben-Hur T, Weidenfeld J, Taylor AN, Yirmiya R (2002) Involvement of brain cytokines in the neurobehavioral disturbances induced by HIV-1 glycoprotein120. Brain Res 933:98-108 (Pubitemid 34270613)
6. Barbaro G, Scozzafava A, Mastrolorenzo A, Supuran CT (2005) Highly active antiretroviral therapy: current state of the art, new agents and their pharmacological interactions useful for improving therapeutic outcome. Curr Pharm Des 11:1805-1843 (Pubitemid 40668138)
7. Belke TW, Wagner JP (2005) The reinforcing property and the rewarding after effect of wheel running in rats: a combination of two paradigms. Behav Processes 68(2):165-172 (Pubitemid 40416869)
8. Bianchi M, Maggi R, Pimpinelli F, Rubino T, Parolaro D, Poli V, Ciliberto G, Panerai AE, Sacerdote P (1999) Presence of a reduced opioid response in interleukin-6 knock out mice. Eur J Neurosci 11:1501-1507 (Pubitemid 29192224)
9. Borner C, Kraus J, Schroder H, Ammer H, Hollt V (2004) Transcriptional regulation of the human mu-opioid receptor gene by interleukin-6. Mol Pharmacol 66:1719-1726. doi:10.1124/mol.104.003806 (Pubitemid 39564799)
10. Chang SL, Beltran JA, Pallur A (2006) HIV-1 gp120 up-regulation of the mu opioid receptor in TPA-differentiated HL-60 cells. Int Immunopharmacol 6:1459-1467 (Pubitemid 44038689)
11. Chang SL, Beltran JA, Swarup S (2007) Expression of the mu opioid receptor in the human immunodeficiency virus type 1 transgenic rat model. J Virol 81:8406-8411 (Pubitemid 47242814)
12. Chang SL, Vigorito M (2006) Role of HIV-1 infection in addictive behavior: A study of an HIV-1 transgenic rat model. Am J Infect Diseases 2:98-106
13. Duncan MJ, Bruce-Keller AJ, Conner C, Knapp PE, Xu R, Nath A, Hauser KF (2008) Effects of chronic expression of the HIVinduced protein, transactivator of transcription, on circadian activity rhythms in mice, with or without morphine. Am J Physiol Regul Integr Comp Physiol 295:R1680-1687
14. El-Hage N, Podhaizer EM, Sturgill J, Hauser KF (2011) Toll-like Receptor Expression and Activation in Astroglia: Differential Regulation by HIV-1 Tat, gp120, and Morphine. Immunol Invest. doi:10.3109/08820139.2011.561904
15. Fitting S, Xu R, Bull C, Buch SK, El-Hage N, Nath A, Knapp PE, Hauser KF (2010) Interactive comorbidity between opioid drug abuse and HIV-1 Tat: chronic exposure augments spine loss and sublethal dendritic pathology in striatal neurons. Am J Pathol 177:1397-1410
16. Fowler CJ, Fraser GL (1994) Mu-, delta-, kappa-opioid receptors and their subtypes. A critical review with emphasis on radioligand binding experiments. Neurochem Int 24:401-426
17. Gianotti N, Lazzarin A (2005) Sequencing antiretroviral drugs for long-lasting suppression of HIV replication. New Microbiol 28:281-297 (Pubitemid 41823926)
18. Gonzalez-Scarano F, Martin-Garcia J (2005) The neuropathogenesis of AIDS. Nat Rev Immunol 5:69-81 (Pubitemid 40070332)
19. Grimm MC, Ben-Baruch A, Taub DD, Howard OM, Resau JH, Wang JM, Ali H, Richardson R, Snyderman R, Oppenheim JJ (1998a) Opiates transdeactivate chemokine receptors: delta and mu opiate receptor-mediated heterologous desensitization. J Exp Med 188:317-325 (Pubitemid 28357760)
20. Grimm MC, Ben-Baruch A, Taub DD, Howard OM, Wang JM, Oppenheim JJ (1998b) Opiate inhibition of chemokine-induced chemotaxis. Ann N Y Acad Sci 840:9-20 (Pubitemid 28302032)
21. Gul H, Yildiz O, Dogrul A, Yesilyurt O, Isimer A (2000) The interaction between IL-1beta and morphine: possible mechanism of the deficiency of morphine-induced analgesia in diabetic mice. Pain 89:39-45
22. Hahn YK, Vo P, Fitting S, Block ML, Hauser KF, Knapp PE (2010) beta-Chemokine production by neural and glial progenitor cells is enhanced by HIV-1 Tat: effects on microglial migration. J Neurochem 114:97-109. doi:10.1111/j.1471-4159.2010.06744.x
23. Horn TF, Huitron-Resendiz S, Weed MR, Henriksen SJ, Fox HS (1998) Early physiological abnormalities after simian immunodeficiency virus infection. Proc Natl Acad Sci U S A 95:15072-15077 (Pubitemid 29003758)
24. Horuk R, Martin AW, Wang Z, Schweitzer L, Gerassimides A, Guo H, Lu Z, Hesselgesser J, Perez HD, Kim J, Parker J, Hadley TJ, Peiper SC (1997) Expression of chemokine receptors by subsets of neurons in the central nervous system. J Immunol 158:2882-2890 (Pubitemid 127470549)
25. Huitron-Resendiz S, Marcondes MC, Flynn CT, Lanigan CM, Fox HS (2007) Effects of simian immunodeficiency virus on the circadian rhythms of body temperature and gross locomotor activity. Proc Natl Acad Sci U S A 104:15138-15143. doi:10.1073/pnas.0707171104 (Pubitemid 47619606)
26. Im HJ, Kang SW, Loh HH (1999) Opioid receptor gene: cytokine response element and the effect of cytokines. Brain Res 829:174-179 (Pubitemid 29251697)
27. Johnston IN, Milligan ED, Wieseler-Frank J, Frank MG, Zapata V, Campisi J, Langer S, Martin D, Green P, Fleshner M, Leinwand L, Maier SF, Watkins LR (2004) A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecalmorphine. J Neurosci 24:7353-7365. doi:10.1523/JNEUROSCI.1850-04.2004 (Pubitemid 39100704)
28. Jones LE, Perelson AS (2005) Opportunistic infection as a cause of transient viremia in chronically infected HIV patients under treatment with HAART. Bull Math Biol 67:1227-1251. doi:10.1016/j.bulm.2005.01.006 (Pubitemid 41323803)
29. Kass MD, Liu X, Vigorito M, Chang L, Chang SL (2010) Methamphetamine- induced behavioral and physiological effects in adolescent and adult HIV-1 transgenic rats. J Neuroimmune Pharmacol 5:566-573. doi:10.1007/s11481-010-9221- z
30. King JE, Eugenin EA, Buckner CM, Berman JW (2006) HIV tat and neurotoxicity. Microbes Infect 8:1347-1357. doi:10.1016/j.micinf.2005.11.014 (Pubitemid 43842005)
31. Kraus J (2009) Regulation of mu-opioid receptors by cytokines. Front Biosci (Schol Ed) 1:164-170
32. Kraus J, Borner C, Giannini E, Hollt V (2003) The role of nuclear factor kappaB in tumor necrosis factor-regulated transcription of the human mu-opioid receptor gene. Mol Pharmacol 64:876-884. doi:10.1124/mol.64.4.876 (Pubitemid 37153056)
33. Larson EB, Carroll ME (2005) Wheel running as a predictor of cocaine self-administration and reinstatement in female rats. Pharmacol Biochem Behav 82:590-600. doi:10.1016/j.pbb.2005.10.015 (Pubitemid 41827603)
34. Lashomb AL, Vigorito M, Chang SL (2009) Further characterization of the spatial learning deficit in the human immunodeficiency virus-1 transgenic rat. J Neurovirol 15:14-24. doi:10.1080/13550280802232996
35. Lett BT, Grant VL, Koh MT, Flynn G (2002) Prior experience with wheel running produces cross-tolerance to the rewarding effect of morphine. Pharmacol Biochem Behav 72:101-105 (Pubitemid 34251314)
36. Liu X, Chang L, Vigorito M, Kass M, Li H, Chang SL (2009) Methamphetamine-induced behavioral sensitization is enhanced in the HIV-1 transgenic rat. J Neuroimmune Pharmacol 4:309-316. doi:10.1007/s11481-009-9160-8
37. Lucas S (2001) Update on the pathology of AIDS. Intensive Crit Care Nurs 17:155-166. doi:10.1054/iccn.2000.1541 (Pubitemid 33667060)
38. Mahajan SD, Schwartz SA, Shanahan TC, Chawda RP, Nair MP (2002) Morphine regulates gene expression of alpha- and betachemokines and their receptors on astroglial cells via the opioid mu receptor. J Immunol 169:3589-3599
39. Mazzucchelli R, Amadio M, Curreli S, Denaro F, Bemis K, ReidW, Bryant J, Riva A, GalliM, Zella D (2004) Establishment of an ex vivo model of monocytes-derived macrophages differentiated from peripheral blood mononuclear cells (PBMCs) from HIV-1 transgenic rats. Mol Immunol 41:979-984. doi:10.1016/j.molimm.2004.06.023 (Pubitemid 39070326)
40. McCarthy L, Wetzel M, Sliker JK, Eisenstein TK, Rogers TJ (2001) Opioids, opioid receptors, and the immune response. Drug Alcohol Depend 62:111-123 (Pubitemid 32195501)
41. Molitor F, Truax SR, Ruiz JD, Sun RK (1998) Association of methamphetamine use during sex with risky sexual behaviors and HIV infection among non-injection drug users. West J Med 168:93-97 (Pubitemid 28100967)
42. Morris RG (1989) Synaptic plasticity and learning: selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5. J Neurosci 9:3040-3057 (Pubitemid 19260822)
43. Mueller DT, Loft A, Eikelboom R (1997) Alternate-day wheel access: effects on feeding, body weight, and running. Physiol Behav 62:905-908 (Pubitemid 27412652)
44. Nath A, Hauser KF, Wojna V, Booze RM, Maragos W, Prendergast M, Cass W, Turchan JT (2002) Molecular basis for interactions of HIV and drugs of abuse. J Acquir Immune Defic Syndr 31(Suppl 2):S62-69 (Pubitemid 35190560)
45. Navia BA, Rostasy K (2005) The AIDS dementia complex: clinical and basic neuroscience with implications for novel molecular therapies. Neurotox Res 8:3-24
46. Peng J, Vigorito M, Liu X, Zhou D, Wu X, Chang SL (2010) The HIV-1 transgenic rat as a model for HIV-1 infected individuals on HAART. J Neuroimmunol 218:94-101. doi:10.1016/j.jneuroim.2009.09.014
47. Peterson PK, Molitor TW, Chao CC (1998) The opioid-cytokine connection. J Neuroimmunol 83(1-2):63-69 (Pubitemid 28280952)
48. Ray PE, Liu XH, Robinson LR, Reid W, Xu L, Owens JW, Jones OD, Denaro F, Davis HG, Bryant JL (2003) A novel HIV-1 transgenic rat model of childhood HIV-1-associated nephropathy. Kidney Int 63:2242-2253. doi:10.1046/j.1523-1755. 2003.00028.x (Pubitemid 36605838)
49. Reid W, Sadowska M, Denaro F, Rao S, Foulke J Jr, Hayes N, Jones O, Doodnauth D, Davis H, Sill A, O'Driscoll P, Huso D, Fouts T, Lewis G, Hill M, Kamin-Lewis R, Wei C, Ray P, Gallo RC, Reitz M, Bryant J (2001) An HIV-1 transgenic rat that develops HIVrelated pathology and immunologic dysfunction. Proc Natl Acad Sci U S A 98:9271-9276. doi:10.1073/pnas.161290298 (Pubitemid 32743906)
50. Rogers TJ, Peterson PK (2003) Opioid G protein-coupled receptors: signals at the crossroads of inflammation. Trends Immunol 24:116-121 (Pubitemid 36263094)
51. Roy S, Barke RA, Loh HH (1998) MU-opioid receptor-knockout mice: role of mu-opioid receptor in morphine mediated immune functions. Brain Res Mol Brain Res 61:190-194 (Pubitemid 28511362)
52. Ruzicka BB, Thompson RC, Watson SJ, Akil H (1996) Interleukin-1 beta-mediated regulation of mu-opioid receptor mRNA in primary astrocyte-enriched cultures. J Neurochem 66:425-428
53. Schafer M, Carter L, Stein C (1994) Interleukin 1 beta and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue. Proc Natl Acad Sci U S A 91:4219-4223
54. Shavit Y, Wolf G, Goshen I, Livshits D, Yirmiya R (2005) Interleukin-1 antagonizes morphine analgesia and underlies morphine tolerance. Pain 115:50-59. doi:10.1016/j.pain.2005.02.003
55. Simpkins CO, Dickey CA, Fink MP (1984) Human neutrophil migration is enhanced by beta-endorphin. Life Sci 34:2251-2255 (Pubitemid 14148235)
56. Sleasman JW, Goodenow MM (2003) 13. HIV-1 infection. J Allergy Clin Immunol 111:S582-592
57. van Epps DE, Saland L (1984) Beta-endorphin and met-enkephalin stimulate human peripheral blood mononuclear cell chemotaxis. J Immunol 132:3046-3053 (Pubitemid 14105695)
58. Vidal EL, Patel NA, Wu G, Fiala M, Chang SL (1998) Interleukin-1 induces the expression of mu opioid receptors in endothelial cells. Immunopharmacology 38:261-266 (Pubitemid 28064596)
59. Vigano A, Trabattoni D, Schneider L, Ottaviani F, Aliffi A, Longhi E, Rusconi S, Clerici M (2006) Failure to eradicate HIV despite fully successful HAART initiated in the first days of life. J Pediatr 148:389-391. doi:10.1016/j.jpeds.2005.11.037
60. Vigorito M, LaShomb AL, Chang SL (2007) Spatial learning and memory in HIV-1 transgenic rats. J Neuroimmune Pharmacol 2:319-328. doi:10.1007/s11481- 007-9078-y
61. Vigorito SLCaM (2006) Role of HIV-1 infection in addictive behavior: a study of a HIV-1 transgenic rat model. Am J Infect Dis 2:98-106
62. Wang J, Barke RA, Charboneau R, Roy S (2005) Morphine impairs host innate immune response and increases susceptibility to Streptococcus pneumoniae lung infection. J Immunol 174:426-434 (Pubitemid 40007431)
63. Werme M, Thoren P, Olson L, Brene S (2000) Running and cocaine both upregulate dynorphin mRNA in medial caudate putamen. Eur J Neurosci 12:2967-2974
64. Zadina JE, Kastin AJ, Harrison LM, Ge LJ, Chang SL (1995) Opiate receptor changes after chronic exposure to agonists and antagonists. Ann N Y Acad Sci 757:353-361