Differential expression of folate receptor alpha in pituitary adenomas and its relationship to tumor behavior

Neurosurgery

Volumn 70, Issue 5, 2012, Pages 1274-1280

  Liu, Xiaohai ^a   Ma, Sihai ^a   Yao, Yong ^a   Li, Guiling ^a   Feng, Ming ^a   Deng, Kan ^a   Dai, Congxin ^a   Cai, Feng ^a   Li, Yan ^a   Zhang, Bo ^b   Wang, Renzhi ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^b DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Folate receptor alpha; Invasiveness; Nonfunctional pituitary adenoma; Targeted imaging and therapy

Indexed keywords

CORTICOTROPIN; FOLATE RECEPTOR 1; GROWTH HORMONE; KI 67 ANTIGEN; MESSENGER RNA; PROLACTIN;

ADULT; AGED; ARTICLE; BRAIN SURGERY; CANCER INVASION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HYPOPHYSIS ADENOMA; IMMUNOHISTOCHEMISTRY; MALE; NONFUNCTIONAL PITUITARY ADENOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR GROWTH;

ADENOMA; ADOLESCENT; ADULT; AGED; DISEASE PROGRESSION; FEMALE; FOLATE RECEPTOR 1; HUMANS; MALE; MIDDLE AGED; NEOPLASM PROTEINS; PITUITARY NEOPLASMS; TISSUE DISTRIBUTION; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84860295450     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/NEU.0b013e3182417e76     Document Type: Article

References (37)

1. Asa SL, Ezzat S. The cytogenesis and pathogenesis of pituitary adenomas. Endocr Rev. 1998;19(6):798-827. (Pubitemid 128506522)
2. Ezzat S, Asa SL. Mechanisms of disease: The pathogenesis of pituitary tumors. Nat Clin Pract Endocrinol Metab. 2006;2(4):220-230.
3. Hansen LK, Molitch ME. Postoperative radiotherapy for clinically nonfunctioning pituitary adenomas. Endocrinologist. 1998;8(2):71-78. (Pubitemid 28180295)
4. Kontogeorgos G. Predictive markers of pituitary adenoma behavior. Neuroendo-crinology. 2006;83(3-4):179-188. (Pubitemid 44578870)
5. Herman V, Fagin J, Gonsky R, Kovacs K, Melmed S. Clonal origin of pituitary adenomas. J Clin Endocrinol Metab. 1990;71(6):1427-1433. (Pubitemid 120032755)
6. Gurlek A, Karavitaki N, Ansorge O, Wass JA. What are the markers of aggressiveness in prolactinomas? Changes in cell biology, extracellular matrix components, angiogenesis and genetics. Eur J Endocrinol. 2007;156(2):143-153. (Pubitemid 46554508)
7. Isono M, Inoue R, Kamida T, Kobayashi H, Matsuyama J. Significance of leptin expression in invasive potential of pituitary adenomas. Clin Neurol Neurosurg. 2003;105(2):111-116. (Pubitemid 36411679)
8. Trouillas J, Daniel L, Guigard MP, et al. Polysialylated neural cell adhesion molecules expressed in human pituitary tumors and related to extrasellar invasion. J Neurosurg. 2003;98(5):1084-1093. (Pubitemid 36460901)
9. Tan H, Ye K, Wang Z, Tang H. CD147 expression as a significant prognostic factor in differentiated thyroid carcinoma. Transl Res. 2008;152(3):143-149.
10. Thapar K, Scheithauer BW, Kovacs K, Pernicone PJ, Laws ER Jr. p53 expression in pituitary adenomas and carcinomas: correlation with invasiveness and tumor growth fractions. Neurosurgery. 1996;38(4):765-771. (Pubitemid 26087884)
11. Takino H, Herman V, Weiss M, Melmed S. Purine-binding factor (nm23) gene expression in pituitary tumors: marker of adenoma invasiveness. J Clin Endocrinol Metab. 1995;80(5):1733-1738.
12. Wang EL, Qian ZR, Rahman MM, et al. Increased expression of HMGA1 correlates with tumour invasiveness and proliferation in human pituitary adenomas. Histopathology. 2010;56(4):501-509.
13. Asa SL, Kovacs K. Clinically non-functioning human pituitary adenomas. Can J Neurol Sci. 1992;19(2):228-235.
14. Katznelson L, Alexander JM, Klibanski A. Clinical review 45: clinically nonfunctioning pituitary adenomas. J Clin Endocrinol Metab. 1993;76(5): 1089-1094. (Pubitemid 23155417)
15. Choi SW, Mason JB. Folate and carcinogenesis: an integrated scheme. J Nutr. 2000;130(2):129-132. (Pubitemid 30073783)
16. Shen F, Ross JF, Wang X, Ratnam M. Identification of a novel folate receptor, a truncated receptor, and receptor type beta in hematopoietic cells: cDNA cloning, expression, immunoreactivity, and tissue specificity. Biochemistry. 1994;33(5): 1209-1215. (Pubitemid 24072451)
17. Weitman SD, Lark RH, Coney LR, et al. Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues. Cancer Res. 1992;52(12): 3396-3401.
18. Toffoli G, Cernigoi C, Russo A, Gallo A, Bagnoli M, Boiocchi M. Overexpression of folate binding protein in ovarian cancers. Int J Cancer. 1997;74(2):193-198. (Pubitemid 27234510)
19. Toffoli G, Russo A, Gallo A, et al. Expression of folate binding protein as a prognostic factor for response to platinum-containing chemotherapy and survival in human ovarian cancer. Int J Cancer. 1998;79(2):121-126. (Pubitemid 28201681)
20. Kim YI. Role of folate in colon cancer development and progression. J Nutr. 2003; 133(1 suppl 1):3731S-3739S.
21. Matsue H, Rothberg KG, Takashima A, Kamen BA, Anderson RG, Lacey SW. Folate receptor allows cells to grow in low concentrations of 5-meth-yltetrahydrofolate. Proc Natl Acad Sci USA. 1992;89(13):6006-6009.
22. Bottero F, Tomassetti A, Canevari S, Miotti S, Menard S, Colnaghi MI. Gene transfection and expression of the ovarian carcinoma marker folate binding protein on NIH/3T3 cells increases cell growth in vitro and in vivo. Cancer Res. 1993;53 (23):5791-5796. (Pubitemid 23360289)
23. Evans CO, Young AN, Brown MR, et al. Novel patterns of gene expression in pituitary adenomas identified by complementary deoxyribonucleic acid microarrays and quantitative reverse transcription-polymerase chain reaction. J Clin Endocrinol Metab. 2001;86(7):3097-3107. (Pubitemid 32673472)
24. Evans CO, Reddy P, Brat DJ, et al. Differential expression of folate receptor in pituitary adenomas. Cancer Res. 2003;63(14):4218-4224. (Pubitemid 36917949)
25. Yao C, Evans CO, Stevens VL, et al. Folate receptor alpha regulates cell proliferation in mouse gonadotroph alphaT3-1 cells. Exp Cell Res. 2009;315(18): 3125-3132.
26. Elnakat H, Ratnam M. Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapy. Adv Drug Deliv Rev. 2004;56 (8):1067-1084. (Pubitemid 38496508)
27. Parker N, Turk MJ, Westrick E, Lewis JD, Low PS, Leamon CP. Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay. Anal Biochem. 2005;338(2):284-293. (Pubitemid 40312593)
28. Lu Y, Low PS. Folate-mediated delivery of macromolecular anticancer therapeutic agents. Adv Drug Deliv Rev. 2002;54(5):675-693. (Pubitemid 35247522)
29. Mathias CJ, Lewis MR, Reichert DE, et al. Preparation of 66Ga-and 68Ga-labeled Ga(III)-deferoxamine-folate as potential folate-receptor-targeted PET radiopharmaceuticals. Nucl Med Biol. 2003;30(7):725-731. (Pubitemid 37123129)
30. Mathias CJ, Wang S, Waters DJ, et al. Indium-111-DTPA-folate as a potential folate-receptor-targeted radiopharmaceutical. J Nucl Med. 1998;39(9):1579-1585. (Pubitemid 28459891)
31. Guo W, Hinkle GH, Lee RJ. 99mTc-HYNIC-folate: a novel receptor-based targeted radiopharmaceutical for tumor imaging. J Nucl Med. 1999;40(9):1563- 1569. (Pubitemid 29428942)
32. Trump DP, Mathias CJ, Yang Z, et al. Synthesis and evaluation of 99mTc(CO) (3)-DTPA-folate as a folate-receptor-targeted radiopharmaceutical. Nucl Med Biol. 2002;29(5):569-573. (Pubitemid 34667118)
33. Reddy JA, Xu LC, Parker N, et al. Preclinical evaluation of (99m)Tc-EC20 for imaging folate receptor-positive tumors. J Nucl Med. 2004;45(5):857-866. (Pubitemid 47618567)
34. Aronov O, Horowitz AT, Gabizon A, Gibson D. Folate-targeted PEG as a potential carrier for carboplatin analogs. Synthesis and in vitro studies. Bioconjug Chem. 2003;14(3):563-574. (Pubitemid 36597366)
35. Ladino CA, Chari RV, Bourret LA, et al. Folate-maytansinoids: target-selective drugs of low molecular weight. Int J Cancer. 1997;73(6):859-864. (Pubitemid 127483041)
36. Reddy JA, Dorton R, Westrick E, et al. Preclinical evaluation of EC145, a folate-vinca alkaloid conjugate. Cancer Res. 2007;67(9):4434-4442. (Pubitemid 46815093)
37. Galt JR, Halkar RK, Evans CO, et al. In vivo assay of folate receptors in nonfunctional pituitary adenomas with 99mTc-folate SPECT/CT. J Nucl Med. 2010;51(11):1716-1723.