Statins improve outcome in murine models of intracranial hemorrhage and traumatic brain injury: A translational approach

Journal of Neurotrauma

Volumn 29, Issue 7, 2012, Pages 1388-1400

  Indraswari, Fransisca ^a,b   Wang, Haichen ^a,b   Lei, Beilei ^a,b   James, Michael L ^a,b   Kernagis, Dawn ^a   Warner, David S ^a,b   Dawson, Hana N ^b   Laskowitz, Daniel T ^a,b  

^a DUKE UNIVERSITY   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

blood brain barrier; HMG CoA reductase inhibitors; intracerebral hemorrhage; neuroinflammation; traumatic brain injury

Indexed keywords

ROSUVASTATIN; SIMVASTATIN; SODIUM CHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HEMORRHAGE; CELL DENSITY; CLINICAL PRACTICE; CONTROLLED STUDY; DISEASE MODEL; DOWN REGULATION; FUNCTIONAL STATUS; GENE EXPRESSION; GLIOSIS; HIPPOCAMPAL CA3 REGION; IMMUNOHISTOCHEMISTRY; MALE; MAZE TEST; MOUSE; NERVE CELL; NERVE CELL DEGENERATION; NONHUMAN; ROTAROD TEST; SINGLE BLIND PROCEDURE; TRANSLATIONAL RESEARCH; TRAUMATIC BRAIN INJURY; TREATMENT OUTCOME;

ANIMALS; BRAIN DAMAGE, CHRONIC; BRAIN INJURIES; DISEASE MODELS, ANIMAL; FLUOROBENZENES; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INTRACRANIAL HEMORRHAGES; MALE; MICE; MICE, INBRED C57BL; NEUROPROTECTIVE AGENTS; PYRIMIDINES; SIMVASTATIN; SULFONAMIDES; TRANSLATIONAL MEDICAL RESEARCH; TREATMENT OUTCOME;

EID: 84860285828     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2011.2117     Document Type: Article

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