Relationship between increased albendazole systemic exposure and changes in single nucleotide polymorphisms on the β-tubulin isotype 1 encoding gene in Haemonchus contortus

Veterinary Parasitology

Volumn 186, Issue 3-4, 2012, Pages 344-349

  Barrère, Virginie ^a   Alvarez, Luis ^b,c   Suarez, Gonzalo ^d   Ceballos, Laura ^b,c   Moreno, Laura ^b,c   Lanusse, Carlos ^b,c   Prichard, Roger K ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSIDAD NACIONAL DEL CENTRO DE LA PROVINCIA DE BUENOS AIRES   (Argentina)

^c Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^d UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

Author keywords

Tubulin; Albendazole; Benzimidazole resistance; Haemonchus contortus; Pyrosequencing; Single nucleotide polymorphism

Indexed keywords

ALBENDAZOLE;

ANIMAL EXPERIMENT; ANTHELMINTIC ACTIVITY; ARTICLE; BETA TUBULIN ISOTYPE 1 ENCODING GENE; CODON; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; FECES ANALYSIS; GENE FREQUENCY; GENE MUTATION; HAEMONCHOSIS; MUTATOR GENE; NONHUMAN; PARASITE CONTROL; PARASITE SURVIVAL; PHENOTYPE; PYROSEQUENCING; RECOMMENDED DRUG DOSE; RUMINANT STOMACH; SHEEP DISEASE; SINGLE NUCLEOTIDE POLYMORPHISM;

ALBENDAZOLE; ALLELES; ANIMALS; ANTHELMINTICS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION; GENOTYPE; HAEMONCHIASIS; HAEMONCHUS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; SEX FACTORS; SHEEP; SHEEP DISEASES; TUBULIN;

HAEMONCHUS CONTORTUS; OVIS ARIES;

EID: 84860258425     PISSN: 03044017     EISSN: 18732550     Source Type: Journal    
DOI: 10.1016/j.vetpar.2011.11.068     Document Type: Article

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