Geometric means provide a biased efficacy result when conducting a faecal egg count reduction test (FECRT)

Veterinary Parasitology

Volumn 161, Issue 1-2, 2009, Pages 162-167

  Dobson, R J ^a   Sangster, N C ^b   Besier, R B ^c   Woodgate, R G ^c  

^a MURDOCH UNIVERSITY   (Australia)

^b CHARLES STURT UNIVERSITY   (Australia)

^c DEPARTMENT OF AGRICULTURE AND FOOD WESTERN AUSTRALIA   (Australia)

Author keywords

Anthelmintic efficacy; Arithmetic means; Drug resistance; Faecal egg count reduction test; Geometric; Monte Carlo simulation; Negative binomial distribution

Indexed keywords

ARTICLE; BINOMIAL DISTRIBUTION; FECAL EGG COUNT REDUCTION TEST; FECES ANALYSIS; GEOMETRY; MONTE CARLO METHOD; NONHUMAN; PARASITE IDENTIFICATION; POISSON DISTRIBUTION; SIMULATION;

ANIMALS; ANTHELMINTICS; BINOMIAL DISTRIBUTION; FECES; MODELS, BIOLOGICAL; MONTE CARLO METHOD; PARASITE EGG COUNT; PARASITIC DISEASES, ANIMAL; SENSITIVITY AND SPECIFICITY;

EID: 62849094203     PISSN: 03044017     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetpar.2008.12.007     Document Type: Article

References (13)

1. Anonymous, 1989. Report of the Working Party for the Animal Health Committee of the Standing Committee on Agriculture. SCA Tech. Rep. Ser. No. 28, Anthelmintic Resistance, CSIRO, Australia.
2. Barger I.A. The statistical distribution of trichostrongylid nematodes in grazing lambs. Int. J. Parasitol. 15 (1985) 645-649
3. Coles G.C., Bauer C., Borgsteede F.H.M., Geerts S., Klei T.R., Taylor M.A., and Waller P.J. World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) methods for the detection of anthelmintic resistance in nematodes of veterinary importance. Vet. Parasitol. 44 (1992) 35-44
4. Dash K.M., Hall E., and Barger I.A. The role of arithmetic and geometric mean worm egg counts in faecal egg count reduction tests and in monitoring strategic drenching programs in sheep. Aust. Vet. J. 65 (1988) 66-68
5. Donald A.D., Morley F.H.W., Waller P.J., Axelsen A., and Donnelly J.R. Availability to grazing sheep of gastrointestinal nematode infections arising from summer contamination of pasture. Aust. J. Agric. Res. 29 (1978) 189-205
6. Miller C.M., Waghorn T.S., Leathwick D.M., and Gilmour M.L. How repeatable is a faecal egg count reduction test?. New Zealand Vet. J. 54 (2006) 323-328
7. Morgan E.R., Cavill L., Curry G.E., Wood R., and Mitchell E.S.E. Effects of aggregation and sample size on composite faecal egg counts in sheep. Vet. Parasitol. 131 (2005) 79-87
8. Schnyder M., Torgerson P.R., Schonmann M., Kohler L., and Hertzberg H. Multiple anthelmintic resistance in Haemonchus contortus isolated from South African Boer goats in Switzerland. Vet. Parasitol. 128 (2005) 285-290
9. Smothers C.D., Sun F., and Dayton A.D. Comparison of arithmetic and geometric means as measures of a central tendency in cattle nematode populations. Vet. Parasitol. 81 (1999) 211-224
10. Torgerson P.R., Schnyder M., and Hertzberg H. Detection of anthelmintic resistance: a comparison of mathematical techniques. Vet. Parasitol. 128 (2005) 291-298
11. Vercruysse J., Holdsworth P., Letonja T., Barth D., Conder G., Hamamoto K., and Okano K. International harmonisation of anthelmintic efficacy guidelines. Vet. Parasitol. 96 (2001) 171-193
12. Vidyashankar A.N., Kaplan R.M., and Chan S. Statistical approach to measure the efficacy of anthelmintic treatment on horse farms. Parasitology 134 (2007) 2027-2039
13. Wood I.B., Amaral N.K., Bairden K., Duncan J.L., Kassai T., Malone J.B., Pankavich J.A., Reinecke R.K., Slocombe O., Taylor S.M., and Vercruysse J. World association for the advancement of veterinary parasitology (WAAVP). Second edition of guidelines for evaluating the efficacy of anthelmintics in ruminants (bovine, ovine, caprine). Vet. Parasitol. 58 (1995) 181-213