Focal immune-mediated white matter demyelination reveals an age-associated increase in axonal vulnerability and decreased remyelination efficiency

American Journal of Pathology

Volumn 180, Issue 5, 2012, Pages 1897-1905

  Hampton, David W ^a   Innes, Neill ^a   Merkler, Doron ^b,c   Zhao, Chao ^d   Franklin, Robin J M ^d   Chandran, Siddharthan ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; RESIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT ANIMAL; AGING; ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL LOSS; CONTROLLED STUDY; DEMYELINATION; DISEASE COURSE; DISEASE PREDISPOSITION; ELECTRON MICROSCOPY; FEMALE; MULTIPLE SCLEROSIS; NERVE CELL LESION; NERVE DEGENERATION; NERVE REGENERATION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROGNOSIS; RAT; REMYELINIZATION; SCHWANN CELL; WHITE MATTER;

AGING; ANIMALS; AXONS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; INTERFERON-GAMMA; MICROSCOPY, ELECTRON; MYELIN PROTEINS; MYELIN SHEATH; NERVE REGENERATION; OLIGODENDROGLIA; RATS; RATS, INBRED LEW; SCHWANN CELLS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84860235395     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.01.018     Document Type: Article

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