-
2
-
-
0037312139
-
Cholesterol is necessary both for the toxic effect of A3β peptides on vascular smooth muscle cells and for A3β binding to vascular smooth muscle cell membranes
-
Subasinghe S, Unabia S, Barrow CJ, Mok SS, Aguilar MI, Small DH: Cholesterol is necessary both for the toxic effect of A3β peptides on vascular smooth muscle cells and for A3β binding to vascular smooth muscle cell membranes. J Neurochem 2003; 84: 471-479.
-
(2003)
J. Neurochem.
, vol.84
, pp. 471-479
-
-
Subasinghe, S.1
Unabia, S.2
Barrow, C.J.3
Mok, S.S.4
Aguilar, M.I.5
Small, D.H.6
-
3
-
-
23044445669
-
Regulation of NMDA receptor trafficking by amyloid-3β
-
Snyder EM, Nong Y, Almeida CG, Paul S, Moran T, Choi EY, Nairn AC, Salter MW, Lombroso PJ, Gouras GK, Greengard P: Regulation of NMDA receptor trafficking by amyloid-3β . Nat Neurosci 2005; 8: 1051-1058.
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 1051-1058
-
-
Snyder, E.M.1
Nong, Y.2
Almeida, C.G.3
Paul, S.4
Moran, T.5
Choi, E.Y.6
Nairn, A.C.7
Salter, M.W.8
Lombroso, P.J.9
Gouras, G.K.10
Greengard, P.11
-
4
-
-
33745894132
-
Does the p75 neurotrophin receptor mediate A3β -induced toxicity in Alzheimer's disease
-
Coulson EJ: Does the p75 neurotrophin receptor mediate A3β -induced toxicity in Alzheimer's disease? J Neurochem 2006; 98: 654-660.
-
(2006)
J. Neurochem.
, vol.98
, pp. 654-660
-
-
Coulson, E.J.1
-
5
-
-
0013615899
-
RAGE and amyloid-3β peptide neurotoxicity in Alzheimer's disease
-
Yan SD, Chen X, Fu J, Chen M, Zhu H, Roher A, Slattery T, Zhao L, Nagashima M, Morser J, Migheli A, Nawroth P, Stern D, Schmidt AM: RAGE and amyloid-3β peptide neurotoxicity in Alzheimer's disease. Nature 1996; 382: 685-691.
-
(1996)
Nature
, vol.382
, pp. 685-691
-
-
Yan, S.D.1
Chen, X.2
Fu, J.3
Chen, M.4
Zhu, H.5
Roher, A.6
Slattery, T.7
Zhao, L.8
Nagashima, M.9
Morser, J.10
Migheli, A.11
Nawroth, P.12
Stern, D.13
Schmidt, A.M.14
-
6
-
-
0034006944
-
3β-Amyloid(1- 42) binds to/α /e 7 nicotinic acetylcholine receptor with high affinity implications for Alzheimer's disease pathology
-
Wang HY, Lee DH, D'Andrea MR, Peterson PA, Shank RP, Reitz AB:3β 42-amyloid(1-42) binds to/α /e 7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology. J Biol Chem 2000; 275: 5626-5632.
-
(2000)
J. Biol. Chem.
, Issue.275
, pp. 5626-5632
-
-
Wang, H.Y.1
Lee, D.H.2
D'Andrea, M.R.3
Peterson, P.A.4
Shank, R.P.5
Reitz, A.B.6
-
7
-
-
0026570528
-
3β -Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
-
Mattson MP, Cheng B, Davis D, Bryant K, Lieberburg I, Rydel RE:3β 42-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci 1992; 12: 376-389.
-
(1992)
J. Neurosci.
, vol.12
, pp. 376-389
-
-
Mattson, M.P.1
Cheng, B.2
Davis, D.3
Bryant, K.4
Lieberburg, I.5
Rydel, R.E.6
-
8
-
-
77956206298
-
A mitocentric view of Alzheimer's disease suggests multi-faceted treatments
-
Gibson GE, Shi Q: A mitocentric view of Alzheimer's disease suggests multi-faceted treatments. J Alzheimers Dis 2010; 20(suppl 2):S591-S607.
-
(2010)
J. Alzheimers. Dis.
, vol.20
, Issue.SUPPL. 2
-
-
Gibson, G.E.1
Shi, Q.2
-
9
-
-
79954486783
-
Does a pro-inflammatory process precede Alzheimer's disease and mild cognitive impairment
-
Ferretti MT, Cuello AC: Does a pro-inflammatory process precede Alzheimer's disease and mild cognitive impairment? Curr Alzheimer Res 2011; 8: 164-174.
-
(2011)
Curr. Alzheimer. Res.
, vol.8
, pp. 164-174
-
-
Ferretti, M.T.1
Cuello, A.C.2
-
10
-
-
79955484857
-
A3β (1- 42) inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-33β
-
Jo J, Whitcomb DJ, Olsen KM, Kerrigan TL, Lo SC, Bru-Mercier G, Dickinson B, Scullion S, Sheng M, Collingridge G, Cho K: A3β (1- 42) inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-33β . Nat Neurosci 2011; 14: 545-547.
-
(2011)
Nat. Neurosci.
, Issue.14
, pp. 545-547
-
-
Jo, J.1
Whitcomb, D.J.2
Olsen, K.M.3
Kerrigan, T.L.4
Lo, S.C.5
Bru-Mercier, G.6
Dickinson, B.7
Scullion, S.8
Sheng, M.9
Collingridge, G.10
Cho, K.11
-
11
-
-
0942265972
-
Amyloid-3β -induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression
-
Liu T, Perry G, Chan HW, Verdile G, Martins RN, Smith MA, Atwood CS: Amyloid-3β -induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression. J Neurochem 2004; 88: 554-563.
-
(2004)
J. Neurochem.
, vol.88
, pp. 554-563
-
-
Liu, T.1
Perry, G.2
Chan, H.W.3
Verdile, G.4
Martins, R.N.5
Smith, M.A.6
Atwood, C.S.7
-
12
-
-
70350304571
-
Calcium dysregulation in Alzheimer's disease: From mechanisms to therapeutic opportunities
-
Yu JT, Chang RC, Tan L: Calcium dysregulation in Alzheimer's disease: from mechanisms to therapeutic opportunities. Prog Neurobiol 2009; 89: 240-255.
-
(2009)
Prog. Neurobiol.
, vol.89
, pp. 240-255
-
-
Yu, J.T.1
Chang, R.C.2
Tan, L.3
-
13
-
-
34548037876
-
Long-term synaptic plasticity in hippocampal interneurons
-
Kullmann DM, Lamsa KP: Long-term synaptic plasticity in hippocampal interneurons. Nat Rev Neurosci 2007; 8: 687-699.
-
(2007)
Nat. Rev. Neurosci.
, vol.8
, pp. 687-699
-
-
Kullmann, D.M.1
Lamsa, K.P.2
-
14
-
-
0034194089
-
Calcium signaling in the ER: Its role in neuronal plasticity and neurodegenerative disorders
-
Mattson MP, LaFerla FM, Chan SL, Leissring MA, Shepel PN, Geiger JD: Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders. Trends Neurosci 2000; 23: 222-229.
-
(2000)
Trends. Neurosci.
, vol.23
, pp. 222-229
-
-
Mattson, M.P.1
LaFerla, F.M.2
Chan, S.L.3
Leissring, M.A.4
Shepel, P.N.5
Geiger, J.D.6
-
15
-
-
77956587739
-
2+elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines
-
2+elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J Neurosci 2010; 30: 11938-11950.
-
(2010)
J. Neurosci.
, vol.30
, pp. 11938-11950
-
-
Zempel, H.1
Thies, E.2
Mandelkow, E.3
Mandelkow, E.M.4
-
16
-
-
0027508926
-
Alzheimer disease amyloidβ protein forms calcium channels in bilayer membranes: Blockade by tromethamine and aluminum
-
Arispe N, Rojas E, Pollard HB: Alzheimer disease amyloidβ protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum. Proc Natl Acad Sci USA 1993; 90: 567-571.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 567-571
-
-
Arispe, N.1
Rojas, E.2
Pollard, H.B.3
-
17
-
-
8744220663
-
Permeabilization of lipid bilayers is a common conformation- dependent activity of soluble amyloid oligomers in protein misfolding diseases
-
Kayed R, Sokolov Y, Edmonds B, McIntire TM, Milton SC, Hall JE, Glabe CG: Permeabilization of lipid bilayers is a common conformation- dependent activity of soluble amyloid oligomers in protein misfolding diseases. J Biol Chem 2004; 279: 46363-46366.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 46363-46366
-
-
Kayed, R.1
Sokolov, Y.2
Edmonds, B.3
McIntire, T.M.4
Milton, S.C.5
Hall, J.E.6
Glabe, C.G.7
-
18
-
-
77957350879
-
Amyloid-3β decreases cell-surface AMPA receptors by increasing intracellular calcium and phosphorylation of GluR2
-
Liu SJ, Gasperini R, Foa L, Small DH: Amyloid-3β decreases cell-surface AMPA receptors by increasing intracellular calcium and phosphorylation of GluR2. J Alzheimers Dis 2010; 21: 655-666.
-
(2010)
J. Alzheimers. Dis.
, vol.21
, pp. 655-666
-
-
Liu, S.J.1
Gasperini, R.2
Foa, L.3
Small, D.H.4
-
19
-
-
60349093657
-
The role of A3β -induced calcium dysregulation in the pathogenesis of Alzheimer's disease
-
Small DH, Gasperini R, Vincent AJ, Hung AC, Foa L: The role of A3β -induced calcium dysregulation in the pathogenesis of Alzheimer's disease. J Alzheimers Dis 2009; 16: 225-233.
-
(2009)
J. Alzheimers. Dis.
, vol.16
, pp. 225-233
-
-
Small, D.H.1
Gasperini, R.2
Vincent, A.J.3
Hung, A.C.4
Foa, L.5
-
20
-
-
47749113650
-
A3β plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks
-
Kuchibhotla KV, Goldman ST, Lattarulo CR, Wu HY, Hyman BT, Bacskai BJ: A3β plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks. Neuron 2008; 59: 214-225.
-
(2008)
Neuron
, vol.59
, pp. 214-225
-
-
Kuchibhotla, K.V.1
Goldman, S.T.2
Lattarulo, C.R.3
Wu, H.Y.4
Hyman, B.T.5
Bacskai, B.J.6
-
21
-
-
0345390947
-
Molecular isoform distribution and glycosylation of acetylcholinesterase are altered in brain and cerebrospinal fluid of patients with Alzheimer's disease
-
Sáez-Valero J, Sberna G, McLean CA, Small DH: Molecular isoform distribution and glycosylation of acetylcholinesterase are altered in brain and cerebrospinal fluid of patients with Alzheimer's disease. J Neurochem 1999; 72: 1600-1608.
-
(1999)
J. Neurochem.
, vol.72
, pp. 1600-1608
-
-
Sáez-Valero, J.1
Sberna, G.2
McLean, C.A.3
Small, D.H.4
-
22
-
-
0031754362
-
Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal fragment (CT100) of the3β- amyloid protein precursor of Alzheimer's disease
-
Sberna G, Sáez-Valero J, Li QX, Czech C, Beyreuther K, Masters CL, McLean CA, Small DH: Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal fragment (CT100) of the3β- amyloid protein precursor of Alzheimer's disease. J Neurochem 1998; 71: 723-731.
-
(1998)
J. Neurochem.
, vol.71
, pp. 723-731
-
-
Sberna, G.1
Sáez-Valero, J.2
Li, Q.X.3
Czech, C.4
Beyreuther, K.5
Masters, C.L.6
McLean, C.A.7
Small, D.H.8
-
23
-
-
0036312401
-
Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition
-
Fodero LR, Sáez-Valero J, McLean CA, Martins RN, Beyreuther K, Masters CL, Robertson TA, Small DH: Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition. J Neurochem 2002; 81: 441-448.
-
(2002)
J. Neurochem.
, vol.81
, pp. 441-448
-
-
Fodero, L.R.1
Sáez-Valero, J.2
McLean, C.A.3
Martins, R.N.4
Beyreuther, K.5
Masters, C.L.6
Robertson, T.A.7
Small, D.H.8
-
24
-
-
0037076870
-
Changes in molecular isoform distribution of acetylcholinesterase in rat cortex and cerebrospinal fluid after intracerebroventricular administration of amyloidβ -peptide
-
Sáez-Valero J, de Ceballos ML, Small DH, de Felipe C: Changes in molecular isoform distribution of acetylcholinesterase in rat cortex and cerebrospinal fluid after intracerebroventricular administration of amyloidβ -peptide. Neurosci Lett 2002; 325: 199-202.
-
(2002)
Neurosci. Lett.
, vol.325
, pp. 199-202
-
-
Sáez-Valero, J.1
De Ceballos, M.L.2
Small, D.H.3
De Felipe, C.4
-
25
-
-
1842375103
-
The amyloidβ -protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells
-
Sberna G, Sáez-Valero J, Beyreuther K, Masters CL, Small DH: The amyloidβ -protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells. J Neurochem 1997; 69: 1177-1184.
-
(1997)
J. Neurochem.
, vol.69
, pp. 1177-1184
-
-
Sberna, G.1
Sáez-Valero, J.2
Beyreuther, K.3
Masters, C.L.4
Small, D.H.5
-
26
-
-
79955715308
-
Routes, destinations and delays: Recent advances in AMPA receptor trafficking
-
Henley JM, Barker EA, Glebov OO: Routes, destinations and delays: recent advances in AMPA receptor trafficking. Trends Neurosci 2011; 34: 258-268.
-
(2011)
Trends. Neurosci.
, vol.34
, pp. 258-268
-
-
Henley, J.M.1
Barker, E.A.2
Glebov, O.O.3
-
27
-
-
2342494269
-
Differential preservation of AMPA receptor subunits in the hippocampi of Alzheimer's disease patients according to Braak stage
-
Carter TL, Rissman RA, Mishizen-Eberz AJ, Wolfe BB, Hamilton RL, Gandy S, Armstrong DM: Differential preservation of AMPA receptor subunits in the hippocampi of Alzheimer's disease patients according to Braak stage. Exp Neurol 2004; 187: 299-309.
-
(2004)
Exp. Neurol.
, vol.187
, pp. 299-309
-
-
Carter, T.L.1
Rissman, R.A.2
Mishizen-Eberz, A.J.3
Wolfe, B.B.4
Hamilton, R.L.5
Gandy, S.6
Armstrong, D.M.7
-
28
-
-
0035112955
-
Glutamate receptor dysregulation in the hippocampus of transgenic mice carrying mutated human amyloid precursor protein
-
Cha JH, Farrell LA, Ahmed SF, Frey A, Hsiao-Ashe KK, Young AB, Penney JB, Locascio JJ, Hyman BT, Irizarry MC: Glutamate receptor dysregulation in the hippocampus of transgenic mice carrying mutated human amyloid precursor protein. Neurobiol Dis 2001; 8: 90-102.
-
(2001)
Neurobiol. Dis.
, vol.8
, pp. 90-102
-
-
Cha, J.H.1
Farrell, L.A.2
Ahmed, S.F.3
Frey, A.4
Hsiao-Ashe, K.K.5
Young, A.B.6
Penney, J.B.7
Locascio, J.J.8
Hyman, B.T.9
Irizarry, M.C.10
-
29
-
-
33845411954
-
AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss
-
Hsieh H, Boehm J, Sato C, Iwatsubo T, Tomita T, Sisodia S, Malinow R: AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss. Neuron 2006; 52: 831-843.
-
(2006)
Neuron
, vol.52
, pp. 831-843
-
-
Hsieh, H.1
Boehm, J.2
Sato, C.3
Iwatsubo, T.4
Tomita, T.5
Sisodia, S.6
Malinow, R.7
-
30
-
-
40649095625
-
Network dysfunction in Alzheimer's disease: Does synaptic scaling drive disease progression
-
Small DH: Network dysfunction in Alzheimer's disease: does synaptic scaling drive disease progression? Trends Mol Med 2008; 14: 103-108.
-
(2008)
Trends. Mol. Med.
, vol.14
, pp. 103-108
-
-
Small, D.H.1
|