Liquid chromatography-tandem mass spectrometric assay for the JAK2 inhibitor CYT387 in plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 895-896, Issue , 2012, Pages 174-177

  Sparidans, Rolf W ^a   Durmus, Selvi ^b   Xu, Ning ^b   Schinkel, Alfred H ^b   Schellens, Jan H M ^a,b   Beijnen, Jos H ^a,b,c  

^a UTRECHT UNIVERSITY   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c SLOTERVAART HOSPITAL   (Netherlands)

Author keywords

CYT387; Human plasma; JAK2 inhibitor; LC MS MS; Mouse plasma

Indexed keywords

CYT387; HUMAN PLASMAS; JAK2 INHIBITOR; LC-MS/MS; MOUSE PLASMA;

ACETONITRILE; CALIBRATION; ELECTROSPRAY IONIZATION; FORMIC ACID; LIQUID CHROMATOGRAPHY; MAMMALS; MASS SPECTROMETRY; METHANOL; POSITIVE IONS; SILICA;

PLASMAS;

CEDIRANIB; CYT 387; JANUS KINASE 2 INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BLOOD SAMPLING; DRUG DETERMINATION; DRUG STABILITY; DRUG STRUCTURE; ELECTROSPRAY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

ANIMALS; BENZAMIDES; CALIBRATION; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; HUMANS; JANUS KINASE 2; LINEAR MODELS; MICE; PROTEIN KINASE INHIBITORS; PYRIMIDINES; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

MUS;

EID: 84860208178     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.03.021     Document Type: Article

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