-
1
-
-
82555196095
-
Systemic lupus erythematosus
-
Tsokos GC. Systemic lupus erythematosus. N. Engl. J. Med. 365(22), 2110-2121 (2011).
-
(2011)
N. Engl. J. Med.
, vol.365
, Issue.22
, pp. 2110-2121
-
-
Tsokos, G.C.1
-
2
-
-
84855172814
-
The pathogenesis of rheumatoid arthritis
-
McInnes IB, Schett G. The pathogenesis of rheumatoid arthritis. N. Engl. J. Med. 365(23), 2205-2219 (2011).
-
(2011)
N. Engl. J. Med.
, vol.365
, Issue.23
, pp. 2205-2219
-
-
McInnes, I.B.1
Schett, G.2
-
3
-
-
80053531618
-
Depletion of autoreactive plasma cells and treatment of lupus nephritis in mice using CEP-33779, a novel, orally active, selective inhibitor of JAK2
-
Lu LD, Stump KL, Wallace NH et al. Depletion of autoreactive plasma cells and treatment of lupus nephritis in mice using CEP-33779, a novel, orally active, selective inhibitor of JAK2. J. Immunol. 187(7), 3840-3853 (2011).
-
(2011)
J. Immunol.
, vol.187
, Issue.7
, pp. 3840-3853
-
-
Lu, L.D.1
Stump, K.L.2
Wallace, N.H.3
-
4
-
-
0001123864
-
JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response
-
Wang LH, Kirken RA, Erwin RA et al. JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response. J. Immunol. 162(7), 3897-3904 (1999). (Pubitemid 29314768)
-
(1999)
Journal of Immunology
, vol.162
, Issue.7
, pp. 3897-3904
-
-
Wang, L.H.1
Kirken, R.A.2
Erwin, R.A.3
Yu, C.-R.4
Farrar, W.L.5
-
5
-
-
77956256590
-
Jak/STAT signaling is involved in the infammatory infltration of the kidneys in MRL/lpr mice
-
Wang S, Yang N, Zhang L et al. Jak/STAT signaling is involved in the infammatory infltration of the kidneys in MRL/lpr mice. Lupus 19 (10), 1171-1180 (2010).
-
(2010)
Lupus
, vol.19
, Issue.10
, pp. 1171-1180
-
-
Wang, S.1
Yang, N.2
Zhang, L.3
-
6
-
-
35548979078
-
Inhibition of JAK/STAT signaling ameliorates mice experimental nephrotic syndrome
-
DOI 10.1159/000108102
-
Li R, Yang N, Zhang L et al. Inhibition of Jak/STAT signaling ameliorates mice experimental nephrotic syndrome. Am. J. Nephrol. 27(6), 580-589 (2007). (Pubitemid 350014945)
-
(2007)
American Journal of Nephrology
, vol.27
, Issue.6
, pp. 580-589
-
-
Li, R.1
Yang, N.2
Zhang, L.3
Huang, Y.4
Zhang, R.5
Wang, F.6
Luo, M.7
Liang, Y.8
Yu, X.9
-
7
-
-
79960245571
-
Pfzer's JAK inhibitor sails through Phase 3 in rheumatoid arthritis
-
Garber K. Pfzer's JAK inhibitor sails through Phase 3 in rheumatoid arthritis. Nat. Biotechnol. 29(6), 467-468 (2011).
-
(2011)
Nat. Biotechnol.
, vol.29
, Issue.6
, pp. 467-468
-
-
Garber, K.1
-
8
-
-
84863012127
-
Novel proteasome inhibitors have a benefcial effect in murine lupus via the dual inhibition of type i interferon and autoantibody secreting cells
-
Ichikawa HT, Conley T, Muchamuel T et al. Novel proteasome inhibitors have a benefcial effect in murine lupus via the dual inhibition of type i interferon and autoantibody secreting cells. Arthritis Rheum. 64(2), 493-503 (2012).
-
(2012)
Arthritis Rheum.
, vol.64
, Issue.2
, pp. 493-503
-
-
Ichikawa, H.T.1
Conley, T.2
Muchamuel, T.3
-
9
-
-
84856103470
-
Novel, orally active, proteasome inhibitor, delanzomib (CEP-18770), ameliorates disease symptoms and glomerulonephritis in two preclinical mouse models of SLE
-
Seavey MM, Lu LD, Stump KL, Wallace NH, Ruggeri BA. Novel, orally active, proteasome inhibitor, delanzomib (CEP-18770), ameliorates disease symptoms and glomerulonephritis in two preclinical mouse models of SLE. Int. Immunopharmacol. 12(1), 257-270 (2012).
-
(2012)
Int. Immunopharmacol.
, vol.12
, Issue.1
, pp. 257-270
-
-
Seavey, M.M.1
Lu, L.D.2
Stump, K.L.3
Wallace, N.H.4
Ruggeri, B.A.5
-
10
-
-
73649123508
-
Interleukin 6 (IL-6) defciency delays lupus nephritis in MRL-Faslpr mice: The IL-6 pathway as a new therapeutic target in treatment of autoimmune kidney disease in systemic lupus erythematosus
-
Cash H, Relle M, Menke J et al. Interleukin 6 (IL-6) defciency delays lupus nephritis in MRL-Faslpr mice: the IL-6 pathway as a new therapeutic target in treatment of autoimmune kidney disease in systemic lupus erythematosus. J. Rheumatol. 37(1), 60-70 (2010).
-
(2010)
J. Rheumatol.
, vol.37
, Issue.1
, pp. 60-70
-
-
Cash, H.1
Relle, M.2
Menke, J.3
-
11
-
-
75749113331
-
Tocilizumab in systemic lupus erythematosus: Data on safety, preliminary effcacy, and impact on circulating plasma cells from an open-label Phase i dosage-escalation study
-
Illei GG, Shirota Y, Yarboro CH et al. Tocilizumab in systemic lupus erythematosus: data on safety, preliminary effcacy, and impact on circulating plasma cells from an open-label Phase I dosage-escalation study. Arthritis Rheum. 62(2), 542-552 (2010).
-
(2010)
Arthritis Rheum.
, vol.62
, Issue.2
, pp. 542-552
-
-
Illei, G.G.1
Shirota, Y.2
Yarboro, C.H.3
-
12
-
-
53849120199
-
High-titer antichromatin antibody is associated with proliferative class IV of lupus nephritis
-
Carvalho JF, Viana VS, Borba EF et al. High-titer antichromatin antibody is associated with proliferative class IV of lupus nephritis. Clin. Rheumatol. 27(11), 1417-1421 (2008).
-
(2008)
Clin. Rheumatol.
, vol.27
, Issue.11
, pp. 1417-1421
-
-
Carvalho, J.F.1
Viana, V.S.2
Borba, E.F.3
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