Automated analysis of lidocaine and its metabolite in plasma by in-tube solid-phase microextraction coupled with LC-UV for pharmacokinetic study

Journal of Separation Science

Volumn 35, Issue 5-6, 2012, Pages 734-741

  Caris, Juciene Aparecida ^a   Silva, Bruno José Gonçalves ^a   Moisés, Elaine Christine Dantas ^b   Lanchote, Vera Lúcia ^a   Queiroz, Maria Eugênia Costa ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

Author keywords

In tube solid phase microextraction; Lidocaine; Liquid chromatography; Parturient women; Plasma samples

Indexed keywords

ANALYTES; AUTOMATED ANALYSIS; COEFFICIENTS OF VARIATIONS; CORRELATION COEFFICIENT; CYCLE NUMBER; DIABETES MELLITUS; DYNAMIC RANGE; HUMAN PLASMAS; IN-TUBE SOLID-PHASE MICROEXTRACTION; IN-TUBE SPME; LIDOCAINE; LIMITS OF QUANTIFICATION; PARTURIENT WOMEN; PHARMACOKINETIC STUDIES; PLASMA PROTEIN; PLASMA SAMPLES; PREGNANT WOMAN; SAMPLE PH; SAMPLE VOLUME; SOLID-PHASE MICROEXTRACTION;

ANESTHESIOLOGY; BIOMOLECULES; LIQUID CHROMATOGRAPHY; METABOLITES; PHARMACOKINETICS; PLASMAS;

TUBES (COMPONENTS);

CAFFEINE; CITALOPRAM; DEETHYLLIDOCAINE; DIAZEPAM; DICLOFENAC; DIPYRONE; EPHEDRINE; FENTANYL; FLUOXETINE; LABETALOL; LIDOCAINE; METOPROLOL; NIFEDIPINE; PHENACETIN; PHENYTOIN; PLASMA PROTEIN; PROPRANOLOL; SERTRALINE; TENOXICAM; TRAMADOL;

ACCURACY; ARTICLE; AUTOMATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; EPIDURAL ANESTHESIA; FEMALE; HUMAN; LIQUID CHROMATOGRAPHY; PH; PLASMA; PREGNANCY DIABETES MELLITUS; PREGNANT WOMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; SOLID PHASE MICROEXTRACTION; ULTRAVIOLET IRRADIATION; VALIDATION PROCESS;

ADULT; ANESTHESIA, EPIDURAL; ANESTHETICS, LOCAL; AUTOMATION; CHROMATOGRAPHY, LIQUID; FEMALE; HUMANS; LIDOCAINE; PREGNANCY; SOLID PHASE MICROEXTRACTION; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 84860188108     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201100872     Document Type: Article

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