Ethanol exposure induces upregulation of specific microRNAs in zebrafish embryos

Toxicological Sciences

Volumn 127, Issue 1, 2012, Pages 18-28

  Soares, Ana Raquel ^a   Pereira, Patrícia M ^a   Ferreira, Violeta ^a   Reverendo, Marisa ^a   Simóes, João ^a   Bezerra, Ana Rita ^a   Moura, Gabriela R ^a   Santos, Manuel A S ^a  

^a UNIVERSITY OF AVEIRO   (Portugal)

Author keywords

Apoptosis; Ethanol toxicity; MicroRNAs; Zebrafish

Indexed keywords

ALCOHOL; MICRORNA;

APOPTOSIS; ARTICLE; CELL CYCLE REGULATION; CONTROLLED STUDY; EMBRYO; FEMALE; GENE EXPRESSION; MALE; MOUSE; NONHUMAN; RAT; RNA TRANSCRIPTION; ZEBRA FISH;

EID: 84860179523     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs068     Document Type: Article

References (47)

1. Adlakha, Y. K., and Saini, N. (2011). MicroRNA-128 downregulates Bax and induces apoptosis in human embryonic kidney cells. Cell. Mol. Life Sci. 68, 1415-1428.
2. Ambros, V. (2004). The functions of animal microRNAs. Nature 431, 350-355.
3. Anthony, B., Zhou, F. C., Ogawa, T., Goodlett, C. R., and Ruiz, J. (2008). Alcohol exposure alters cell cycle and apoptotic events during early neurulation. Alcohol Alcohol. 43, 261-273.
4. Aroor, A. R., and Shukla, S. D. (2004). MAP kinase signaling in diverse effects of ethanol. Life Sci. 74, 2339-2364.
5. Bartel, D. P. (2004). MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 116, 281-297.
6. Bilotta, J., Barnett, J. A., Hancock, L., and Saszik, S. (2004). Ethanol exposure alters zebrafish development: A novel model of fetal alcohol syndrome. Neurotoxicol. Teratol. 26, 737-743.
7. Caldwell, K. K., Sheema, S., Paz, R. D., Samudio-Ruiz, S. L., Laughlin, M. H., Spence, N. E., Roehlk, M. J., Alcon, S. N., and Allan, A. M. (2008). Fetal alcohol spectrum disorder-associated depression: Evidence for reductions in the levels of brain-derived neurotrophic factor in a mouse model. Pharmacol. Biochem. Behav. 90, 614-624.
8. Camarillo, C., and Miranda, R. C. (2008). Ethanol exposure during neurogenesis induces persistent effects on neural maturation: Evidence from an ex vivo model of fetal cerebral cortical neuroepithelial progenitor maturation. Gene Expr. 14, 159-171.
9. Care, A., Catalucci, D., Felicetti, F., Bonci, D., Addario, A., Gallo, P., Bang, M. L., Segnalini, P., Gu, Y., Dalton, N. D., et al. (2007). MicroRNA-133 controls cardiac hypertrophy. Nat. Med. 13, 613-618.
10. Carvan, M. J., Loucks, E., Weber, D. N., and Williams, F. E. (2004). Ethanol effects on the developing zebrafish: Neurobehavior and skeletal morphogenesis. Neurotoxicol. Teratol. 26, 757-768.
11. Cheah, F. S., Winkler, C., Jabs, E. W., and Chong, S. S. (2010). Tgfbeta3 regulation of chondrogenesis and osteogenesis in zebrafish is mediated through formation and survival of a subpopulation of the cranial neural crest. Mech. Dev. 127, 329-344.
12. Chen, D., Zhang, Z., Li, M., Wang, W., Li, Y., Rayburn, E. R., Hill, D. L., Wang, H., and Zhang, R. (2007). Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: Binding to MDM2, stabilization of p53 protein, and activation of p53 function. Oncogene 26, 5029-5037.
13. Dee, C. T., Hirst, C. S., Shih, Y. H., Tripathi, V. B., Patient, R. K., and Scotting, P. J. (2008). Sox3 regulates both neural fate and differentiation in the zebrafish ectoderm. Dev. Biol. 320, 289-301.
14. Duan, J., Ba, Q., Wang, Z., Hao, M., Li, X., Hu, P., Zhang, D., Zhang, R., and Wang, H. (2011). Knockdown of ribosomal protein S7 causes developmental abnormalities via p53 dependent and independent pathways in zebrafish. Int. J. Biochem. Cell Biol. 43, 1218-1227.
15. Elsen, G. E., Choi, L. Y., Millen, K. J., Grinblat, Y., and Prince, V. E. (2008). Zic1 and Zic4 regulate zebrafish roof plate specification and hindbrain ventricle morphogenesis. Dev. Biol. 314, 376-392.
16. Fan, C. Y., Cowden, J., Simmons, S. O., Padilla, S., and Ramabhadran, R. (2010). Gene expression changes in developing zebrafish as potential markers for rapid developmental neurotoxicity screening. Neurotoxicol. Teratol. 32, 91-98.
17. Ferri, A. L., Lin, W., Mavromatakis, Y. E., Wang, J. C., Sasaki, H., Whitsett, J. A., and Ang, S. L. (2007). Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosagedependent manner. Development 134, 2761-2769.
18. Filipowicz, W., Bhattacharyya, S. N., and Sonenberg, N. (2008). Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight? Nat. Rev. Genet. 9, 102-114.
19. Giraldez, A. J., Cinalli, R. M., Glasner, M. E., Enright, A. J., Thomson, J. M., Baskerville, S., Hammond, S. M., Bartel, D. P., and Schier, A. F. (2005). MicroRNAs regulate brain morphogenesis in zebrafish. Science 308, 833-838.
20. Hill, R. M., Hegemier, S., and Tennyson, L. M. (1989). The fetal alcohol syndrome: A multihandicapped child. Neurotoxicology 10, 585-595.
21. Hou, L., Wang, D., and Baccarelli, A. (2011). Environmental chemicals and microRNAs. Mutat. Res. 714, 105-112.
22. Huang, Q. H., Gumireddy, K., Schrier, M., Le Sage, C., Nagel, R., Nair, S., Egan, D. A., Li, A. P., Huang, G. H., Klein-Szanto, A. J., et al. (2008). The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat. Cell Biol. 10, 202-210.
23. Ikeda, S., Kong, S. W., Lu, J., Bisping, E., Zhang, H., Allen, P. D., Golub, T. R., Pieske, B., and Pu, W. T. (2007). Altered microRNA expression in human heart disease. Physiol. Genomics 31, 367-373.
24. Ismail, S., Buckley, S., Budacki, R., Jabbar, A., and Gallicano, G. I. (2010). Screening, diagnosing and prevention of fetal alcohol syndrome: Is this syndrome treatable? Dev. Neurosci. 32, 91-100.
25. Izzotti, A., Calin, G. A., Steele, V. E., Croce, C. M., and De, F. S. (2009). Relationships of microRNA expression in mouse lung with age and exposure to cigarette smoke and light. FASEB J. 23, 3243-3250.
26. Lee, J. E. (1997). NeuroD and neurogenesis. Dev. Neurosci. 19, 27-32.
27. Lindahl, T., Landberg, G., Ahlgren, J., Nordgren, H., Norberg, T., Klaar, S., Holmberg, L., and Bergh, J. (2004). Overexpression of cyclin E protein is associated with specific mutation types in the p53 gene and poor survival in human breast cancer. Carcinogenesis 25, 375-380.
28. Liu, L., Chen, R., Huang, S., Wu, Y., Li, G., Zhang, B., Liu, Q., Yin, D., and Liang, Y. (2012). miR-153 sensitized the K562 cells to As2O3-induced apoptosis. Med. Oncol. 29, 243-247.
29. Marrs, J. A., Clendenon, S. G., Ratcliffe, D. R., Fielding, S. M., Liu, Q., and Bosron, W. F. (2010). Zebrafish fetal alcohol syndrome model: Effects of ethanol are rescued by retinoic acid supplement. Alcohol 44, 707-715.
30. Nyholm, M. K., Abdelilah-Seyfried, S., and Grinblat, Y. (2009). A novel genetic mechanism regulates dorsolateral hinge-point formation during zebrafish cranial neurulation. J. Cell Sci. 122, 2137-2148.
31. Pfaffl, M. W., Horgan, G. W., and Dempfle, L. (2002). Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res. 30, e36.
32. Pietrzykowski, A. Z., Friesen, R. M., Martin, G. E., Puig, S. I., Nowak, C. L., Wynne, P. M., Siegelmann, H. T., and Treistman, S. N. (2008). Posttranscriptional regulation of BK channel splice variant stability by miR-9 underlies neuroadaptation to alcohol. Neuron 59, 274-287.
33. Reimers, M. J., Flockton, A. R., and Tanguay, R. L. (2004). Ethanol- and acetaldehyde-mediated developmental toxicity in zebrafish. Neurotoxicol. Teratol. 26, 769-781.
34. Reimers, M. J., La Du, J. K., Periera, C. B., Giovanini, J., and Tanguay, R. L. (2006). Ethanol-dependent toxicity in zebrafish is partially attenuated by antioxidants. Neurotoxicol. Teratol. 28, 497-508.
35. Sathyan, P., Golden, H. B., and Miranda, R. C. (2007). Competing interactions between micro-RNAs determine neural progenitor survival and proliferation after ethanol exposure: Evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium. J. Neurosci. 27, 8546-8557.
36. Schembri, F., Sridhar, S., Perdomo, C., Gustafson, A. M., Zhang, X., Ergun, A., Lu, J., Liu, G., Zhang, X., Bowers, J., et al. (2009). MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proc. Natl. Acad. Sci. U.S.A. 106, 2319-2324.
37. Silber, J., Lim, D. A., Petritsch, C., Persson, A. I., Maunakea, A. K., Yu, M., Vandenberg, S. R., Ginzinger, D. G., James, C. D., Costello, J. F., et al. (2008). miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med. 6, 14.
38. Soares, A. R., Pereira, P. M., Santos, B., Egas, C., Gomes, A. C., Arrais, J., Oliveira, J. L., Moura, G. R., and Santos, M. A. S. (2009). Parallel DNA pyrosequencing unveils new zebrafish microRNAs. BMC Genomics 10, 195.
39. Sylvain, N. J., Brewster, D. L., and Ali, D. W. (2010). Zebrafish embryos exposed to alcohol undergo abnormal development of motor neurons and muscle fibers. Neurotoxicol. Teratol. 32, 472-480.
40. Tay, Y. M. S., Tam, W. L., Ang, Y. S., Gaughwin, P. M., Yang, H., Wang, W. J., Liu, R. B., George, J., Ng, H. H., Perera, R. J., et al. (2008). MicroRNA-134 modulates the differentiation of mouse embryonic stem cells, where it causes post-transcriptional attenuation of Nanog and LRH1. Stem Cells 26, 17-29.
41. Vangipuram, S. D., and Lyman, W. D. (2010). Ethanol alters cell fate of fetal human brain-derived stem and progenitor cells. Alcohol. Clin. Exp. Res. 34, 1574-1583.
42. Volinia, S., Calin, G. A., Liu, C. G., Ambs, S., Cimmino, A., Petrocca, F., Visone, R., Iorio, M., Roldo, C., Ferracin, M., et al. (2006). A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. U.S.A. 103, 2257-2261.
43. Wang, L. L., Zhang, Z., Li, Q., Yang, R., Pei, X., Xu, Y., Wang, J., Zhou, S. F., and Li, Y. (2009). Ethanol exposure induces differential microRNA and target gene expression and teratogenic effects which can be suppressed by folic acid supplementation. Hum. Reprod. 24, 562-579.
44. Xu, J., Liao, X., and Wong, C. (2010). Downregulations of B-cell lymphoma 2 and myeloid cell leukemia sequence 1 by microRNA 153 induce apoptosis in a glioblastoma cell line DBTRG-05MG. Int. J. Cancer 126, 1029-1035.
45. Yin, V. P., Thomson, J. M., Thummel, R., Hyde, D. R., Hammond, S. M., and Poss, K. D. (2008). Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish. Genes Dev. 22, 728-733.
46. Zhang, L., Li, Y. Y., Zeng, H. C., Wei, J., Wan, Y. J., Chen, J., and Xu, S. Q. (2011). MicroRNA expression changes during zebrafish development induced by perfluorooctane sulfonate. J. Appl. Toxicol. 31, 210-222.
47. Zhao, Y., Ransom, J. F., Li, A., Vedantham, V., von Drehle, M., Muth, A. N., Tsuchihashi, T., McManus, M. T., Schwartz, R. J., and Srivastava, D. (2007). Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell 129, 303-317.