Transthyretin is a metallopeptidase with an inducible active site

Biochemical Journal

Volumn 443, Issue 3, 2012, Pages 769-778

  Liz, Márcia A ^a   Leite, Sérgio C ^a   Juliano, Luiz ^b   Saraiva, Maria J ^a,c   Damas, Ana M ^a,c   Bur, Daniel ^d   Sousa, Mónica M ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF PORTO   (Portugal)

^d ACTELION PHARMACEUTICALS LTD   (Switzerland)

Author keywords

Amyloid peptide; Apolipoprotein A I; Metallopeptidase; Transthyretin; Zinc

Indexed keywords

4 (2 AMINOETHYL)BENZENESULFONYL FLUORIDE; COPPER ION; MANGANESE; METALLOPROTEINASE; PREALBUMIN; SERINE; ZINC ION;

ARTICLE; BINDING SITE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; HYDROPHOBICITY; IN VITRO STUDY; MUTAGENESIS; NONHUMAN; PH; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN MODIFICATION; PROTEIN STRUCTURE;

CATALYTIC DOMAIN; CHROMATOGRAPHY, GEL; HYDROGEN-ION CONCENTRATION; KINETICS; METALLOPROTEASES; PREALBUMIN; PROTEIN CONFORMATION; PROTEOLYSIS;

EID: 84860178075     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111690     Document Type: Article

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