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Volumn 32, Issue 17, 2012, Pages 5821-5832

A reversible early oxidized redox state that precedes macromolecular ROS damage in aging nontransgenic and 3xTg-AD mouse neurons

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CALCIUM ION; CYTOCHROME C; FLAVINE ADENINE NUCLEOTIDE; GLUTATHIONE; NICOTINAMIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

EID: 84860170321     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.6192-11.2012     Document Type: Article
Times cited : (103)

References (52)
  • 2
    • 77949318560 scopus 로고    scopus 로고
    • Metabolic reprogramming, caloric restriction and aging
    • Anderson RM, Weindruch R (2010) Metabolic reprogramming, caloric restriction and aging. Trends Endocrinol Metab 21:134-141.
    • (2010) Trends Endocrinol Metab , vol.21 , pp. 134-141
    • Anderson, R.M.1    Weindruch, R.2
  • 3
    • 0030896414 scopus 로고    scopus 로고
    • Isolation and culture of adult rat hippocampal neurons
    • Brewer GJ (1997) Isolation and culture of adult rat hippocampal neurons. J Neurosci Methods 71:143-155.
    • (1997) J Neurosci Methods , vol.71 , pp. 143-155
    • Brewer, G.J.1
  • 4
    • 76749126321 scopus 로고    scopus 로고
    • Epigenetic oxidative redox shift (EORS) theory of aging unifies the free radical and insulin signaling theories
    • Brewer GJ (2010) Epigenetic oxidative redox shift (EORS) theory of aging unifies the free radical and insulin signaling theories. Exp Gerontol 45:173-179.
    • (2010) Exp Gerontol , vol.45 , pp. 173-179
    • Brewer, G.J.1
  • 5
    • 34250718676 scopus 로고    scopus 로고
    • Isolation and culture of adult neurons and neurospheres
    • Brewer GJ, Torricelli JR (2007) Isolation and culture of adult neurons and neurospheres. Nat Protoc 2:1490-1498.
    • (2007) Nat Protoc , vol.2 , pp. 1490-1498
    • Brewer, G.J.1    Torricelli, J.R.2
  • 6
    • 0027226219 scopus 로고
    • Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serumfree medium combination
    • Brewer GJ, Torricelli JR, Evege EK, Price PJ (1993) Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serumfree medium combination. J Neurosci Res 35:567-576.
    • (1993) J Neurosci Res , vol.35 , pp. 567-576
    • Brewer, G.J.1    Torricelli, J.R.2    Evege, E.K.3    Price, P.J.4
  • 7
    • 29844450628 scopus 로고    scopus 로고
    • Prevention of age-related dysregulation of calcium dynamics by estrogen in neurons
    • Brewer GJ, Reichensperger JD, Brinton RD (2006) Prevention of age-related dysregulation of calcium dynamics by estrogen in neurons. Neurobiol Aging 27:306-317.
    • (2006) Neurobiol Aging , vol.27 , pp. 306-317
    • Brewer, G.J.1    Reichensperger, J.D.2    Brinton, R.D.3
  • 8
    • 77956649516 scopus 로고    scopus 로고
    • Age-related toxicity of amyloid-beta associated with increased pERK and pCREB in primary hippocampal neurons: Reversal by blueberry extract
    • Brewer GJ, Torricelli JR, Lindsey AL, Kunz EZ, Neuman A, Fisher DR, Joseph JA (2010) Age-related toxicity of amyloid-beta associated with increased pERK and pCREB in primary hippocampal neurons: reversal by blueberry extract. J Nutr Biochem 21:991-998.
    • (2010) J Nutr Biochem , vol.21 , pp. 991-998
    • Brewer, G.J.1    Torricelli, J.R.2    Lindsey, A.L.3    Kunz, E.Z.4    Neuman, A.5    Fisher, D.R.6    Joseph, J.A.7
  • 9
    • 18244390483 scopus 로고    scopus 로고
    • Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications
    • Bubber P, Haroutunian V, Fisch G, Blass JP, Gibson GE (2005) Mitochondrial abnormalities in Alzheimer brain: mechanistic implications. Ann Neurol 57:695-703.
    • (2005) Ann Neurol , vol.57 , pp. 695-703
    • Bubber, P.1    Haroutunian, V.2    Fisch, G.3    Blass, J.P.4    Gibson, G.E.5
  • 10
    • 0032408711 scopus 로고    scopus 로고
    • Structural and functional changes in proteins induced by free radicalmediated oxidative stress and protective action of the antioxidants N-tert-butyl-alpha-phenylnitrone and vitamin
    • Butterfield DA, Koppal T, Howard B, Subramaniam R, Hall N, Hensley K, Yatin S, Allen K, Aksenov M, Aksenova M, Carney J (1998) Structural and functional changes in proteins induced by free radicalmediated oxidative stress and protective action of the antioxidants N-tert-butyl-alpha-phenylnitrone and vitamin E. Ann N Y Acad Sci 854:448-462.
    • (1998) E. Ann N Y Acad Sci , vol.854 , pp. 448-462
    • Butterfield, D.A.1    Koppal, T.2    Howard, B.3    Subramaniam, R.4    Hall, N.5    Hensley, K.6    Yatin, S.7    Allen, K.8    Aksenov, M.9    Aksenova, M.10    Carney, J.11
  • 11
  • 12
    • 0004463340 scopus 로고
    • Respiratory enzymes in oxidative phosphorylation, VI: The effects of adenosine diphosphate on azide-treated mitochondria
    • Chance B, Williams GR (1956) Respiratory enzymes in oxidative phosphorylation, VI: the effects of adenosine diphosphate on azide-treated mitochondria. J Biol Chem 221:477-489.
    • (1956) J Biol Chem , vol.221 , pp. 477-489
    • Chance, B.1    Williams, G.R.2
  • 13
    • 0018786822 scopus 로고
    • Oxidationreduction ratio studies of mitochondria in freeze-trapped samples. NADH and flavoprotein fluorescence signals
    • Chance B, Schoener B, Oshino R, Itshak F, Nakase Y (1979) Oxidationreduction ratio studies of mitochondria in freeze-trapped samples. NADH and flavoprotein fluorescence signals. J Biol Chem 254:4764-4771.
    • (1979) J Biol Chem , vol.254 , pp. 4764-4771
    • Chance, B.1    Schoener, B.2    Oshino, R.3    Itshak, F.4    Nakase, Y.5
  • 14
    • 0037162538 scopus 로고    scopus 로고
    • Redox systems of the cell: Possible links and implications
    • Das KC, White CW (2002) Redox systems of the cell: possible links and implications. Proc Natl Acad Sci U S A 99:9617-9618.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 9617-9618
    • Das, K.C.1    White, C.W.2
  • 15
    • 1642483509 scopus 로고    scopus 로고
    • Neurodegenerative diseases and oxidative stress
    • Emerit J, Edeas M, Bricaire F (2004) Neurodegenerative diseases and oxidative stress. Biomed Pharmacother 58:39-46.
    • (2004) Biomed Pharmacother , vol.58 , pp. 39-46
    • Emerit, J.1    Edeas, M.2    Bricaire, F.3
  • 16
    • 0024597774 scopus 로고
    • Nicotinamide adenine dinucleotide fluorescence spectroscopy and imaging of isolated cardiac myocytes
    • Eng J, Lynch RM, Balaban RS (1989) Nicotinamide adenine dinucleotide fluorescence spectroscopy and imaging of isolated cardiac myocytes. Biophys J 55:621-630.
    • (1989) Biophys J , vol.55 , pp. 621-630
    • Eng, J.1    Lynch, R.M.2    Balaban, R.S.3
  • 17
    • 58149267462 scopus 로고    scopus 로고
    • Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau
    • Green KN, Steffan JS, Martinez-Coria H, Sun X, Schreiber SS, Thompson LM, LaFerla FM (2008) Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau. J Neurosci 28:11500-11510.
    • (2008) J Neurosci , vol.28 , pp. 11500-11510
    • Green, K.N.1    Steffan, J.S.2    Martinez-Coria, H.3    Sun, X.4    Schreiber, S.S.5    Thompson, L.M.6    Laferla, F.M.7
  • 19
    • 0032531735 scopus 로고    scopus 로고
    • Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation
    • Hensley K, Maidt ML, Yu Z, Sang H, Markesbery WR, Floyd RA (1998) Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation. J Neurosci 18:8126-8132.
    • (1998) J Neurosci , vol.18 , pp. 8126-8132
    • Hensley, K.1    Maidt, M.L.2    Yu, Z.3    Sang, H.4    Markesbery, W.R.5    Floyd, R.A.6
  • 20
    • 13144306087 scopus 로고    scopus 로고
    • Amyloid precursor protein (APP) and its derivatives change after cellular energy depletion: An in vitro-study
    • Hoyer A, Bardenheuer HJ, Martin E, Plaschke K (2005) Amyloid precursor protein (APP) and its derivatives change after cellular energy depletion: an in vitro-study. J Neural Transm 112:239-253.
    • (2005) J Neural Transm , vol.112 , pp. 239-253
    • Hoyer, A.1    Bardenheuer, H.J.2    Martin, E.3    Plaschke, K.4
  • 21
    • 0023737618 scopus 로고
    • Glucose metabolism as the site of the primary abnormality in early-onset dementia of Alzheimer type?
    • Hoyer S, Oesterreich K, Wagner O (1988) Glucose metabolism as the site of the primary abnormality in early-onset dementia of Alzheimer type? J Neurol 235:143-148.
    • (1988) J Neurol , vol.235 , pp. 143-148
    • Hoyer, S.1    Oesterreich, K.2    Wagner, O.3
  • 22
    • 0020641469 scopus 로고
    • Monobromobimane: A substrate for the fluorometric assay of glutathione transferase
    • Hulbert PB, Yakubu SI (1983) Monobromobimane: a substrate for the fluorometric assay of glutathione transferase. J Pharm Pharmacol 35: 384-386.
    • (1983) J Pharm Pharmacol , vol.35 , pp. 384-386
    • Hulbert, P.B.1    Yakubu, S.I.2
  • 23
    • 33744962865 scopus 로고    scopus 로고
    • Redefining oxidative stress
    • Jones DP (2006) Redefining oxidative stress. Antioxid Redox Signal 8:1865-1879.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1865-1879
    • Jones, D.P.1
  • 24
    • 73249119801 scopus 로고    scopus 로고
    • Age-related deficiencies in complex I endogenous substrate availability and reserve capacity of complex IV in cortical neuron electron transport
    • Jones TT, Brewer GJ (2010) Age-related deficiencies in complex I endogenous substrate availability and reserve capacity of complex IV in cortical neuron electron transport. Biochim Biophys Acta 1797: 167-176.
    • (2010) Biochim Biophys Acta , vol.1797 , pp. 167-176
    • Jones, T.T.1    Brewer, G.J.2
  • 26
    • 0028651951 scopus 로고
    • Calcium hypothesis of Alzheimer's disease and brain aging
    • Khachaturian ZS (1994) Calcium hypothesis of Alzheimer's disease and brain aging. Ann N Y Acad Sci 747:1-11.
    • (1994) Ann N Y Acad Sci , vol.747 , pp. 1-11
    • Khachaturian, Z.S.1
  • 27
    • 0029056469 scopus 로고
    • High-performance liquid chromatography analysis of oxidized and reduced pyridine dinucleotides in specific brain regions
    • Klaidman LK, Leung AC, Adams JD Jr (1995) High-performance liquid chromatography analysis of oxidized and reduced pyridine dinucleotides in specific brain regions. Anal Biochem 228:312-317.
    • (1995) Anal Biochem , vol.228 , pp. 312-317
    • Klaidman, L.K.1    Leung, A.C.2    Adams Jr., J.D.3
  • 28
    • 0035895736 scopus 로고    scopus 로고
    • Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide
    • Klaidman LK, Mukherjee SK, Adams JD Jr (2001) Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide. Biochim Biophys Acta 1525:136-148.
    • (2001) Biochim Biophys Acta , vol.1525 , pp. 136-148
    • Klaidman, L.K.1    Mukherjee, S.K.2    Adams Jr., J.D.3
  • 29
    • 0025343774 scopus 로고
    • Quantitative analysis of glutathione in rat central nervous system: Comparison of GSH in infant brain with that in adult brain
    • Kudo H, Kokunai T, Kondoh T, Tamaki N, Matsumoto S (1990) Quantitative analysis of glutathione in rat central nervous system: comparison of GSH in infant brain with that in adult brain. Brain Res 511:326-328.
    • (1990) Brain Res , vol.511 , pp. 326-328
    • Kudo, H.1    Kokunai, T.2    Kondoh, T.3    Tamaki, N.4    Matsumoto, S.5
  • 30
    • 0022972426 scopus 로고
    • Brain alpha-ketoglutarate dehydrogenase complex: Kinetic properties, regional distribution, and effects of inhibitors
    • Lai JC, Cooper AJ (1986) Brain alpha-ketoglutarate dehydrogenase complex: kinetic properties, regional distribution, and effects of inhibitors. J Neurochem 47:1376-1386.
    • (1986) J Neurochem , vol.47 , pp. 1376-1386
    • Lai, J.C.1    Cooper, A.J.2
  • 31
    • 84855386003 scopus 로고    scopus 로고
    • Influence of viral vector-mediated delivery of superoxide dismutase and catalase to the hippocampus on spatial learning and memory during aging
    • Lee WH, Kumar A, Rani A, Herrera J, Xu J, Someya S, Foster TC (2012) Influence of viral vector-mediated delivery of superoxide dismutase and catalase to the hippocampus on spatial learning and memory during aging. Antioxid Redox Signal 16:339-350.
    • (2012) Antioxid Redox Signal , vol.16 , pp. 339-350
    • Lee, W.H.1    Kumar, A.2    Rani, A.3    Herrera, J.4    Xu, J.5    Someya, S.6    Foster, T.C.7
  • 33
    • 77950908035 scopus 로고    scopus 로고
    • " Control" laboratory rodents are metabolically morbid: Why it matters
    • Martin B, Ji S, Maudsley S, Mattson MP (2010) "Control" laboratory rodents are metabolically morbid: why it matters. Proc Natl Acad Sci U S A 107:6127-6133.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 6127-6133
    • Martin, B.1    Ji, S.2    Maudsley, S.3    Mattson, M.P.4
  • 36
    • 68649104009 scopus 로고    scopus 로고
    • Mitochondrial calcium function and dysfunction in the central nervous system
    • Nicholls DG (2009) Mitochondrial calcium function and dysfunction in the central nervous system. Biochim Biophys Acta 1787:1416-1424.
    • (2009) Biochim Biophys Acta , vol.1787 , pp. 1416-1424
    • Nicholls, D.G.1
  • 39
    • 0344845132 scopus 로고    scopus 로고
    • Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease
    • Oddo S, Caccamo A, Kitazawa M, Tseng BP, LaFerla FM (2003b) Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease. Neurobiol Aging 24:1063-1070.
    • (2003) Neurobiol Aging , vol.24 , pp. 1063-1070
    • Oddo, S.1    Caccamo, A.2    Kitazawa, M.3    Tseng, B.P.4    Laferla, F.M.5
  • 40
    • 34147219139 scopus 로고    scopus 로고
    • Simultaneous age-related depolarization of mitochondrial membrane potential and increased mitochondrial reactive oxygen species production correlate with age-related glutamate excitotoxicity in rat hippocampal neurons
    • Parihar MS, Brewer GJ (2007) Simultaneous age-related depolarization of mitochondrial membrane potential and increased mitochondrial reactive oxygen species production correlate with age-related glutamate excitotoxicity in rat hippocampal neurons. J Neurosci Res 85:1018-1032.
    • (2007) J Neurosci Res , vol.85 , pp. 1018-1032
    • Parihar, M.S.1    Brewer, G.J.2
  • 41
    • 48249155387 scopus 로고    scopus 로고
    • Age-related decreases in NAD(P)H and glutathione cause redox declines before ATP loss during glutamate treatment of hippocampal neurons
    • Parihar MS, Kunz EA, Brewer GJ (2008) Age-related decreases in NAD(P)H and glutathione cause redox declines before ATP loss during glutamate treatment of hippocampal neurons. J Neurosci Res 86:2339-2352.
    • (2008) J Neurosci Res , vol.86 , pp. 2339-2352
    • Parihar, M.S.1    Kunz, E.A.2    Brewer, G.J.3
  • 42
    • 0037448097 scopus 로고    scopus 로고
    • Age-related changes in neuronal glucose uptake in response to glutamate and beta-amyloid
    • Patel JR, Brewer GJ (2003) Age-related changes in neuronal glucose uptake in response to glutamate and beta-amyloid. J Neurosci Res 72:527-536.
    • (2003) J Neurosci Res , vol.72 , pp. 527-536
    • Patel, J.R.1    Brewer, G.J.2
  • 43
    • 67349279818 scopus 로고    scopus 로고
    • Proteomic identification of HNE-bound proteins in early Alzheimer disease: Insights into the role of lipid peroxidation in the progression of AD
    • Reed TT, Pierce WM, Markesbery WR, Butterfield DA (2009) Proteomic identification of HNE-bound proteins in early Alzheimer disease: insights into the role of lipid peroxidation in the progression of AD. Brain Res 1274:66-76.
    • (2009) Brain Res , vol.1274 , pp. 66-76
    • Reed, T.T.1    Pierce, W.M.2    Markesbery, W.R.3    Butterfield, D.A.4
  • 47
    • 24644456470 scopus 로고    scopus 로고
    • Calcium dysregulation in Alzheimer's disease: Recent advances gained from genetically modified animals
    • Smith IF, Green KN, LaFerla FM (2005a) Calcium dysregulation in Alzheimer's disease: recent advances gained from genetically modified animals. Cell Calcium 38:427-437.
    • (2005) Cell Calcium , vol.38 , pp. 427-437
    • Smith, I.F.1    Green, K.N.2    Laferla, F.M.3
  • 48
    • 24644460177 scopus 로고    scopus 로고
    • Enhanced caffeine-induced Ca2_ release in the 3xTg-AD mouse model of Alzheimer's disease
    • Smith IF, Hitt B, Green KN, Oddo S, LaFerla FM (2005b) Enhanced caffeine-induced Ca2_ release in the 3xTg-AD mouse model of Alzheimer's disease. J Neurochem 94:1711-1718.
    • (2005) J Neurochem , vol.94 , pp. 1711-1718
    • Smith, I.F.1    Hitt, B.2    Green, K.N.3    Oddo, S.4    Laferla, F.M.5
  • 49
    • 0031776586 scopus 로고    scopus 로고
    • Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4-dinitrophenylhydrazine
    • Smith MA, Sayre LM, Anderson VE, Harris PL, Beal MF, Kowall N, Perry G (1998) Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4-dinitrophenylhydrazine. J Histochem Cytochem 46:731-735.
    • (1998) J Histochem Cytochem , vol.46 , pp. 731-735
    • Smith, M.A.1    Sayre, L.M.2    Anderson, V.E.3    Harris, P.L.4    Beal, M.F.5    Kowall, N.6    Perry, G.7
  • 50
    • 33646945317 scopus 로고    scopus 로고
    • Enhanced ryanodine receptor recruitment contributes to Ca2_ disruptions in young, adult, and aged Alzheimer's disease mice
    • Stutzmann GE, Smith I, Caccamo A, Oddo S, Laferla FM, Parker I (2006) Enhanced ryanodine receptor recruitment contributes to Ca2_ disruptions in young, adult, and aged Alzheimer's disease mice. J Neurosci 26:5180-5189.
    • (2006) J Neurosci , vol.26 , pp. 5180-5189
    • Stutzmann, G.E.1    Smith, I.2    Caccamo, A.3    Oddo, S.4    Laferla, F.M.5    Parker, I.6
  • 51
    • 70149093436 scopus 로고    scopus 로고
    • Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
    • Yao J, Irwin RW, Zhao L, Nilsen J, Hamilton RT, Brinton RD (2009) Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 106:14670-14675.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 14670-14675
    • Yao, J.1    Irwin, R.W.2    Zhao, L.3    Nilsen, J.4    Hamilton, R.T.5    Brinton, R.D.6
  • 52
    • 37549068090 scopus 로고    scopus 로고
    • NAD+/NADH and NADP+/NADPH in cellular functions and cell death: Regulation and biological consequences
    • Ying W (2008) NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences. Antioxid Redox Signal 10:179-206.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 179-206
    • Ying, W.1


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