Increases in muscle blood flow after a mixed meal are impaired at all stages of type 2 diabetes

Clinical Endocrinology

Volumn 76, Issue 6, 2012, Pages 825-830

  Lambadiari, Vaia ^a   Mitrou, Panayota ^b   Maratou, Eirini ^b   Raptis, Athanassios ^a   Raptis, Sotirios A ^a,b   Dimitriadis, George ^a  

^a NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

^b Hellenic National Center for Research   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; GLUCOSE; INSULIN; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIABETIC PATIENT; FOREARM MUSCLE BLOOD FLOW; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HUMAN; HYPERGLYCEMIA; IMPAIRED GLUCOSE TOLERANCE; INSULIN RESISTANCE; LIPID METABOLISM; METABOLIC PARAMETERS; MUSCLE BLOOD FLOW; NON INSULIN DEPENDENT DIABETES MELLITUS; PLETHYSMOGRAPHY; POSTPRANDIAL HYPERGLYCEMIA; PRIORITY JOURNAL; RADIAL ARTERY;

ADULT; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; FATTY ACIDS, NONESTERIFIED; FEMALE; HUMANS; INSULIN; MALE; MIDDLE AGED; MUSCLE, SKELETAL; POSTPRANDIAL PERIOD; TRIGLYCERIDES;

EID: 84860146046     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2011.04211.x     Document Type: Article

References (38)

1. Hadi, A.R.H., &, Suwaidi, J.A.L., (2007) Endothelial dysfunction in diabetes mellitus. Vascular Health Risk Management, 3, 853-876.
2. Kim, J.A., Montagnani, M., Koh, K.K., et al. (2006) Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation, 113, 1888-1904.
3. Sonne, M.P., Højbjerre, L., Alibegovic, A.A., et al. (2009) Impaired endothelial function and insulin action in first-degree relatives of patients with type 2 diabetes mellitus. Metabolism, 58, 93-101.
4. Newman, J.M., Ross, R.M., Richards, S.M., et al. (2007) Insulin and contraction increase nutritive blood flow in rat muscle in vivo determined by microdialysis of L-[14C]glucose. Journal of Physiology, 585, 217-229.
5. Rattigan, S., Bradley, E.A., Richards, S.M., et al. (2006) Muscle metabolism and control of capillary blood flow: insulin and exercise. Essays in Biochemistry, 42, 133-144.
6. Zhang, L., Vincent, M.A., Richards, S.M., et al. (2004) Insulin sensitivity of muscle capillary recruitment in vivo. Diabetes, 53, 447-453.
7. Kahn, B.B., &, Flier, J.S., (2000) Obesity and insulin resistance. Journal of Clinical Investigation, 106, 473-481.
8. Keske, M.A., Clerk, L.H., Price, W.J., et al. (2009) Obesity blunts microvascular recruitment in human forearm muscle after a mixed meal. Diabetes Care, 32, 1672-1677.
9. Coppack, S.W., Fisher, R.M., Humphreys, S.M., et al. (1996) Carbohydrate metabolism in insulin resistance: glucose uptake and lactate production by adipose and forearm tissues in vivo before and after a mixed meal. Clinical Science (London), 90, 409-415.
10. Dimitriadis, G., Lambadiari, V., Mitrou, P., et al. (2007) Impaired postprandial blood flow in adipose tissue may be an early marker of insulin resistance in Type 2 Diabetes. Diabetes Care, 30, 3128-3130.
11. Caballero, E., Arora, S., Saouaf, R., et al. (1999) Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes. Diabetes, 48, 1856-1862.
12. Laakso, M., Edelman, S.V., Brechtel, G., et al. (1992) Impaired insulin-mediated skeletal muscle blood flow in patients with NIDDM. Diabetes, 41, 1076-1083.
13. Laakso, M., Edelman, S.V., Brechtel, G., et al. (1990) Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man. A novel mechanism for insulin resistance. Journal of Clinical Investigation, 85, 1844-1852.
14. Bonadonna, R.C., Saccomani, M.P., Del Prato, S., et al. (1998) Role of tissue-specific blood flow and tissue recruitment in insulin-mediated glucose uptake of human skeletal muscle. Circulation, 21, 234-241.
15. Ferrannini, E., Taddei, S., Santoro, D., et al. (1988) Independent stimulation of glucose metabolism and Na+-K+ exchange by insulin in the human forearm. American Journal of Physiology, Endocrinology and Metabolism, 255, 953-958.
16. Jackson, R.A., Hamling, J.B., Blix, P.M., et al. (1986) The influence of gradient hyperglycemia with and without physiological hyperinsulinemia on forearm glucose uptake and other metabolic responses in man. Journal of Clinical Endocrinology and Metabolism, 63, 594-604.
17. Yki-Jarvinen, H., (1993) Action of insulin on glucose metabolism in vivo. Bailliere's Clinical Endocrinology and Metabolism, 7, 903-928.
18. Shimabukuro, M., Higa, N., Asahi, T., et al. (2003) Hypoadiponectinemia is closely linked to endothelial dysfunction in man. Journal of Clinical Endocrinology and Metabolism, 88, 3236-3240.
19. Matthews, D., Hosker, J., Rudenski, A., et al. (1985) Homeostasis model assessment: insulin resistance and b-cell function from fasting plasma glucose and insulin concentrations. Diabetologia, 28, 412-419.
20. Gutt, M., Davis, C.L., Spitzer, S.B., et al. (2000) Validation of the insulin sensitivity index (ISI1,120): comparison with other measures. Diabetes Research and Clinical Practice, 47, 177-184.
21. Radikova, Z., (2003) Assessment of insulin sensitivity/resistance in epidemiological studies. Endocrine Regularions, 37, 189-194.
22. Barrett, E.J., Eggleston, E.M., Inyard, A.C., et al. (2009) The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin action. Diabetologia, 52, 752-764.
23. Clarke, M.G., Wallis, M.G., Barrett, E.G., et al. (2003) Blood flow and muscle metabolism: a focus on insulin action. American Journal of Physiology, Endocrinology and Metabolism, 284, 241-258.
24. Liu, Z., Liu, J., Jahn, L.A., et al. (2009) Infusing lipid raises plasma free fatty acids and induces insulin resistance in muscle microvasculature. Journal of Clinical Endocrinology and Metabolism, 94, 3543-3549.
25. Clerk, L.H., Rattigan, S., Clark, M.G., et al. (2002) Lipid infusion impairs physiologic insulin-mediated capillary recruitment and muscle glucose uptake in vivo. Diabetes, 51, 1138-1145.
26. Evans, K., Burdge, G.C., Wootton, S.A., et al. (2002) Regulation of dietary fatty acid entrapment in subcutaneous adipose tissue and skeletal muscle. Diabetes, 51, 2684-2690.
27. Miles, J.M., Park, Y.S., Walewicz, D., et al. (2004) Fate of lipoprotein lipase-generated glycerol and free fatty acids. Diabetes, 53, 521-527.
28. Kelley, D.E., &, Goodpaster, B.H., (2001) Skeletal muscle triglycerides; An aspect of regional adiposity and insulin resistance. Diabetes Care, 24, 933-941.
29. Riemens, S.C., Sluiter, W.J., &, Dullaart, R.P.F., (2000) Enhanced escape of non-esterified fatty acids from tissue uptake: its role in impaired insulin-induced lowering of total rate of appearance in obesity and Type II diabetes. Diabetologia, 43, 416-426.
30. Evans, K., Clark, M.L., &, Frayn, K.N., (1999) Effects of an oral and intravenous fat load on adipose tissue and forearm lipid metabolism. American Journal of Physiology, Endocrinology and Metabolism, 276, 241-248.
31. Coppack, S.W., Persson, M., Judd, R.L., et al. (1999) Glycerol and non-esterified fatty acid metabolism in human muscle and adipose tissue in vivo. American Journal of Physiology, Endocrinology and Metabolism, 39, 233-240.
32. Balletshofer, B.M., Rittig, K., Enderle, M.D., et al. (2000) Endothelial dysfunction is detectable in young normotensive first-degree relatives of subjects with type 2 diabetes in association with insulin resistance. Circulation, 18, 1780-1784.
33. OstergÃrd, T., Nyholm, B., Hansen, T.K., et al. (2006) Endothelial function and biochemical vascular markers in first-degree relatives of type 2 diabetic patients: the effect of exercise training. Metabolism, 55, 1508-1515.
34. Kriketos, A.D., Greenfield, J.R., Peake, P.W., et al. (2004) Inflammation, insulin resistance, and adiposity: a study of first-degree relatives of type 2 diabetic subjects. Diabetes Care, 27, 2033-2040.
35. Price, T.B., Perseghin, G., Duleba, A., et al. (1996) NMR studies of muscle glycogen synthesis in insulin-resistant offspring of parents with non-insulin-dependent diabetes mellitus immediately after glycogen-depleting exercise. Proceedings of the National Academy of Sciences USA, 93, 5329-5334.
36. Goldfine, A.B., Beckman, J.A., Betensky, R.A., et al. (2006) Family history of diabetes is a major determinant of endothelial function. Journal of the American College of Cardiology, 47, 2456-2461.
37. Hirata, K., Kadirvelu, A., Di, T.M., et al. (2007) Coronary vasomotor function is abnormal in first-degree relatives of patients with type 2 diabetes. Diabetes Care, 30, 150-153.
38. Tesauro, M., Rizza, S., Iantorno, M., et al. (2007) Vascular, metabolic, and inflammatory abnormalities in normoglycemic offspring of patients with type 2 diabetes mellitus. Metabolism, 56, 413-419.