Synthesis of tetracyclic indoles via intramolecular α-arylation of ketones

Journal of Organic Chemistry

Volumn 77, Issue 8, 2012, Pages 4123-4130

  Hellal, Malik ^a   Singh, Shambhavi ^a   Cuny, Gregory D ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF HOUSTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARYL HALIDES; ARYLATIONS; ONE-POT REACTION; SEQUENTIAL ADDITION;

AROMATIC COMPOUNDS; CHEMICAL REACTIONS; PALLADIUM COMPOUNDS;

KETONES;

1 [2 (1 BENZYL 4 CHLOROINDOL 3 YL)CYCLOHEX 1 ENYL]PROPAN 1 ONE; 1 [2 (1 BENZYL 4 CHLOROINDOL 3 YL)CYCLOPENT 1 ENYL]PROPAN 1 ONE; 1 [2 (1 BENZYL 4 CHLOROINDOL 3 YL)PHENYL] 2 METHYLPROPAN 1 ONE; 1 [2 (1 BENZYL 4 CHLOROINDOL 3 YL)PHENYL] 2 PHENYLETHANONE; 1 [2 (1 BENZYL 4 CHLOROINDOL 3 YL)PHENYL]PROPAN 1 ONE; 1 [2 (1 BENZYL 4 CHLOROINDOL 3 YL)PYRIDIN 3 YL]PROPAN 1 ONE; 1 [3 (1 BENZYL 4 CHLOROINDOL 3 YL)PYRAZIN 2 YL]PROPAN 1 ONE; 1 [3 (1 BENZYL 4 CHLOROINDOL 3 YL)PYRIDIN 4 YL]PROPAN 1 ONE; 1 [4 (1 BENZYL 4 CHLOROINDOL 3 YL)BENZO[1,3]DIOXOL 5 YL]PROPAN 1 ONE; 1 BENZYL 3 BROMO 4 CHLOROINDOLE; 1 BENZYL 4 BROMO 3 IODOINDOLE; 1 BENZYL 4 CHLORO 3 (4,4,5,5 TETRAMETHYL 1,3,2 DIOXABOROLAN 2 YL) INDOLE; 1 BENZYL 4 CHLORO 3 IODOINDOLE; INDOLE DERIVATIVE; KETONE; PALLADIUM COMPLEX; UNCLASSIFIED DRUG;

ARTICLE; ARYLATION; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG STRUCTURE; ONE POT SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; SUBSTITUTION REACTION;

CATALYSIS; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; INDOLES; KETONES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PALLADIUM; STEREOISOMERISM;

EID: 84860112655     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo300052z     Document Type: Article

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