Simultaneous determination and pharmacokinetics of protein unbound aspirin and salicylic acid in rat blood and brain by microdialysis: An application to herbal-drug interaction

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 895-896, Issue , 2012, Pages 31-38

  Shaw, Lee Hsin ^a   Tsai, Tung Hu ^a,b  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI CITY HOSPITAL   (Taiwan)

Author keywords

Aspirin; Bu yang huan wu tang; Herbal medicine; Pharmacokinetics; Stroke; Traditional Chinese medicine

Indexed keywords

ASPIRIN; BU-YANG-HUAN-WU-TANG; HERBAL MEDICINES; STROKE; TRADITIONAL CHINESE MEDICINE;

BLOOD; DIALYSIS; DRUG INTERACTIONS; LIQUID CHROMATOGRAPHY; MEDICINE; RATS; SKIN;

PHARMACOKINETICS;

ACETYLSALICYLIC ACID; BU YANG HUAN WU TANG EXTRACT; CHINESE DRUG; PLANT EXTRACT; SALICYLIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLEEDING TIME; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DETERMINATION; DRUG HALF LIFE; DRUG HYDROLYSIS; DRUG POTENTIATION; LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANIMALS; AREA UNDER CURVE; ASPIRIN; BLEEDING TIME; BRAIN CHEMISTRY; DRUG STABILITY; DRUGS, CHINESE HERBAL; HERB-DRUG INTERACTIONS; MALE; MICRODIALYSIS; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SALICYLIC ACID;

RATTUS;

EID: 84860110779     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.03.010     Document Type: Article

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