Measurement of salicylic acid in human serum using stable isotope dilution and gas chromatography-mass spectrometry

Analytical Biochemistry

Volumn 354, Issue 2, 2006, Pages 274-278

  Battezzati, A ^a   Fiorillo, G ^a   Spadafranca, A ^a   Bertoli, S ^a   Testolin, G ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Gas chromatography mass spectrometry; Salycilic acid; Serum; Stable isotopes

Indexed keywords

ISOTOPES; MASS SPECTROMETRY; SALICYLIC ACID;

GAS CHROMATOGRAPHY-MASS SPECTROMETRY; NATURALLY OCCURRING; POPULATION STUDIES; QUANTIFICATION LIMIT; SERUM; STABLE ISOTOPE DILUTION; STABLE ISOTOPES; TERT-BUTYLDIMETHYLSILYL DERIVATIVES;

GAS CHROMATOGRAPHY;

ACETAMIDE DERIVATIVE; ACETIC ACID ETHYL ESTER; ACETYLSALICYLIC ACID; ETHER; N METHYL N (TERT BUTYLDIMETHYLSILYL)TRIFLUOROACETAMIDE; SALICYLIC ACID; STABLE ISOTOPE; UNCLASSIFIED DRUG;

ARTICLE; BODY FLUID; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GAS CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; ISOTOPE DILUTION ASSAY; LIQUID LIQUID EXTRACTION; MALE; MASS SPECTROMETRY; NORMAL HUMAN; PRIORITY JOURNAL; STANDARD;

EID: 33745214202     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2006.05.009     Document Type: Article

References (17)

1. Stanley P., and Hegedus R. Aspirin-the first hundred years. Biologist 47 5 (2000) 269-271
2. Marcus A.J. Aspirin as the prophylaxis against colorectal cancer. N. Engl. J. Med. 333 (1995) 656-658
3. Hebert P.R., and Hennekens C.H. An overview of the 4 randomized trials of aspirin therapy in the primary prevention of vascular disease. Arch. Intern. Med. 160 (2000) 3123-3127
4. Sanmuganathan P.S., Ghahramani P., Jackson P.R., Wallis E.J., and Ramsay L.E. Aspirin for primary prevention of coronary heart disease: safety and absolute benefit related to coronary risk derived from meta-analysis of randomised trials. Heart 85 (2001) 265-271
5. Gasche C. Review article: the chemoprevention of colorectal carcinoma. Aliment. Pharmacol. Ther. 20 Suppl 4 (2004) 31-35
6. Higgs G.A., Salmon J.A., Henderson B., and Vane J.R. Pharmacokinetics of aspirin and salicylate in relation to inhibition of arachidonate cyclooxygenase and anti-inflammatory activity. Proc. Natl. Acad. Sci. USA 84 (1987) 1417-1420
7. Dangl J. Innate immunity. Plants just say NO to pathogens. Nature 394 6693 (1998) 525-527
8. Dempsey D.A., and Klessig D.F. Salicylic acid, active oxygen species and systemic acquired resistance in plants. Trends Cell Biol. 4 9 (1994) 334-338
9. Robertson G.L., and Kermode W.J. Salicylic acid in fresh and canned fruit and vegetables. J. Sci. Food Agric. 32 (1981) 833-836
10. Swain A.R., Dutton S.P., and Truswell A.S. Salicylates in foods. J. Am. Diet. Assoc. 85 (1985) 950-960
11. Janssen P.L., Hollman P.C., Venema D.P., van Staveren W.A., and Katan M.B. Salicylates in foods. Nutr. Rev. 54 11 Pt 1 (1996) 357-359 Review
12. Paterson J.R., Blacklock C., Campbell G., Wiles D., and Lawrence J.R. The identification of salicylates as normal constituents of serum: a link between diet and health?. J. Clin. Pathol. 51 (1998) 502-505
13. Blacklock C.J., Lawrence J.R., Wiles D., Malcolm E.A., Gibson I.H., Kelly C.J., and Paterson J.R. Salicylic acid in the serum of subjects not taking aspirin. Comparison of salicylic acid concentrations in the serum of vegetarians, non-vegetarians, and patients taking low dose aspirin. J. Clin. Pathol. 54 (2001) 553-555
14. Kees F., Jehnich D., and Grobecker H. Simultaneous determination of acetylsalicylic acid and salicylic acid in human plasma by high-performance liquid chromatography. J. Chromatogr. B 677 (1996) 172-177
15. Zhang K., and Zuo Y. GC-MS Determination of Flavonoids and Phenolic and benzoic Acids in Human Plasma after Consumption of Cranberry juice. J. Agric. Food Chem. 52 (2004) 222-227
16. Luo X., and Lehotay D.C. Determination of hydroxyl radicals using salicylates as a trapping agent by gas chromatography-mass spectrometry. Clin. Biochem. 30 (1997) 41-46
17. San Romerio A., Fiorillo G., Terruzzi I., Senesi P., Testolin G., and Battezzati A. Measurement of DNA methylation using stable isotope dilution and gas chromatography-mass spectrometry. Anal. Biochem. 336 (2005) 158-163