Aripiprazole in children with tourette's disorder and co-morbid attention-deficit/hyperactivity disorder: A 12-week, open-label, preliminary study

Journal of Child and Adolescent Psychopharmacology

Volumn 22, Issue 2, 2012, Pages 120-125

  Masi, Gabriele ^a   Gagliano, Antonella ^b   Siracusano, Rosamaria ^b   Berloffa, Stefano ^a   Calarese, Tiziana ^b   Ilardo, Giovanna ^b   Pfanner, Chiara ^a   Magazù, Angela ^a   Cedro, Clemente ^b  

^a DEPARTMENT OF DEVELOPMENTAL NEUROSCIENCE   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ARIPIPRAZOLE;

ADOLESCENT; AGITATION; ARTICLE; ATTENTION DEFICIT DISORDER; BLOOD PRESSURE; BODY HEIGHT; BODY WEIGHT; CHILD; CLINICAL ARTICLE; DISEASE SEVERITY; DRUG DOSE REDUCTION; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG TOLERABILITY; ELECTROCARDIOGRAM; EVENING DOSAGE; FEMALE; GILLES DE LA TOURETTE SYNDROME; HUMAN; INCREASED APPETITE; MALE; MORNING DOSAGE; NAUSEA; OBSESSIVE COMPULSIVE DISORDER; OPEN STUDY; OUTCOME ASSESSMENT; PROLACTIN BLOOD LEVEL; SCHOOL CHILD; SEDATION; SIDE EFFECT; TIC; TREMOR;

ADOLESCENT; ANTIPSYCHOTIC AGENTS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CHILD; FEMALE; HUMANS; LOGISTIC MODELS; MALE; OBSESSIVE-COMPULSIVE DISORDER; PIPERAZINES; QUINOLONES; SEVERITY OF ILLNESS INDEX; TOURETTE SYNDROME; TREATMENT OUTCOME;

EID: 84860004948     PISSN: 10445463     EISSN: 15578992     Source Type: Journal    
DOI: 10.1089/cap.2011.0081     Document Type: Article

References (49)

1. Achenbach TM, Edelbrock C: Manual for the Child Behavior Checklist. Burlington, VA: University of Vermont, 1983.
2. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. (DSM-IV). Washington, DC: American Psychiatric Association; 1994.
3. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed., Text Revision (DSM-IV-TR). Washington, DC: American Psychiatric Association; 2000.
4. Benjamin E, Salek S: Stimulant-Atypical antipsychotic interaction and acute dystonia. J Am Acad Child Adolesc Psychiatry 44:510-512, 2005. (Pubitemid 40720948)
5. Bloch MH, Panza KE, Landeros-Weisenberger A, Leckman JF: Metaanalysis: Treatment of attention-deficit/hyperactivity disorder in children with co-morbid tic disorders. J Am Acad Child Adolesc Psychiatry 48:884-893, 2009.
6. Budman C, Coffey BJ, Shechter R, Schrock M, Wieland N, Spirgel A, Simon E: Aripiprazole in children and adolescents with Tourette disorder with and without explosive outbursts. J Child Adolesc. Psychopharmacol. 18:509-515, 2008.
7. Burris KD, Molski TF, Xu C, et al.: Arpiprazole, a novel antipsychotic, is a high-Affinity partial agonist at human dopamine D2 receptors. J. Pharmacol. Exp Ther 302:381-389, 2002. (Pubitemid 34680462)
8. Cohen DJ, Detlor J, Lowe TL, Kremintzer M, Shaywitz BA: Stimulant medication in Tourette's Syndrome. JAMA 248:1062-1063, 1982.
9. Cui YH, Zheng Y, Yang YP, Liu J, Li J: Effectiveness and tolerability of aripiprazole in children and adolescents with Tourette's disorder: A pilot study in China. J Child Adolesc. Psychopharmacol. 20:291-298, 2010.
10. Du JC, Chiu TF, Lee KM, Wu HL, Yang YC, Hsu SY, Sun CS, Hwang B, Leckman JF: Tourette syndrome in children: An updated review. Pediatr Neonatol 51:255-264, 2010.
11. Du YS, Li HF, Vance A, Zhong YQ, Jiao FY, Wang HM, Wang MJ, Su LY, Yu DL, Ma SW, Wu JB: Randomized double-blind multicentre placebo-controlled clinical trial of the clonidine adhesive patch for the treatment of tic disorders. Aust N Z J Psychiatry 42:807-813, 2008.
12. DuPaul GJ, Power TJ, Anastopoulos AD, Reid R: ADHD Rating Scale IV: Checklist, Norms and Clinical Interpretation, New York, NY: Guilford Press, 1998.
13. Findling RL, Short EJ, Leskovec T, Townsend LD, Demeter CA, McNamara NK, Stansbrey RJ: Aripiprazole in children with attention-deficit/hyperactivity disorder. J Child Adolesc. Psychopharmacol. 18:347-354, 2008.
14. Gao K, Muzina D, Gajwani P, Calabrese J: Efficacy of typical and atypical antipsychotics for primary and comorbid anxiety symptoms or disorders: A review. J Clin Psychiatry 67:1327-1340, 2006. (Pubitemid 44583379)
15. Geller DA, Biederman J, Faraone SV, Cradock K, Hagermoser L, Zaman N, et al.: Attention-deficit/hyperactivity disorder in children and adolescents with obsessive compulsive disorder: Fact or artifact? J Am Acad Child Adolesc Psychiatry 41:52-58, 2002. (Pubitemid 38337477)
16. Grados MA, Mathews CA: Tourette Sindrome Association International Consortium for Genetics. Biol Psychiatry 64, 219-225, 2008.
17. Guy W: ECDEU Assessment Manual for Psychopharmacology, Revised. Rockville, MD: U.S. Department of Health, Education and Welfare, 1976.
18. Hedderick EF, Morris CM, Singer HS. Double-blind, crossover study of clonidine and levetiracetam in Tourette syndrome. Pediatr Neurol 40:420-425, 2009.
19. Hoekstra PJ, Steenhuis MP, Troost PW, Korf J, Kallenberg CG, Minderaa RB: Relative contribution of attention-deficit hyperactivity disorder, obsessive-compulsive disorder, and tic severity to social and behavioural problems in tic disorders. J Dev Behav Pediatr 25:272-279, 2004. (Pubitemid 39199573)
20. Hollis CP, Thompson A. Acute dyskinesia on starting methylphenidate after risperidone withdrawal. Pediatr Neurol 37:287-288, 2007. (Pubitemid 47446152)
21. Kaplan G, Newcorn JH: Pharmacotherapy for child and adolescent attention-deficit hyperactivity disorder. Pediatr Clin North Am 58:99-120, 2011.
22. Kaufman J, Birmaher B, Brent D, Rao U, Flynn C, Moreci P, Williamson D, Ryan N: Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): Initial reliability and validity data. J Am Acad Child Adolesc Psychiatry 36:980-988, 1997. (Pubitemid 27272932)
23. Jain R, Segal S, Kollins SH, et al.: Clonidine extended release tablets for pediatric patients with attention deficit-hyperactivity disorder J Am Acad Child Adolesc Psychiatry 50:171-179, 2011.
24. Leckman JF, Riddle MA, Hardin MT, Ort SI, Swartz KL, Stevenson J, Cohen DJ: The Yale Global Tic Severity Scale: Initial testing of a clinician-rated scale of tic severity. J Am Acad Child Adolesc Psychiatry 28:566-573, 1989. (Pubitemid 19196295)
25. Lyon GJ, Samar S, Jummani R, Hirsch S, Spirgel A, Goldman R, Coffey BJ: Aripiprazole in children and adolescents with Tourette's disorder: An open-label safety and tolerability study. J Child Adolesc. Psychopharmacol. 19:623-633, 2009.
26. Masi G, Millepiedi S, Mucci M, Bertini N, Pfanner C, Arcangeli F: Comorbidity of obsessive-compulsive disorder and ADHD in referred children and adolescents. Compr Psychiatry 47:42-47, 2006. (Pubitemid 41736149)
27. Masi G, Pfanner C, Millepiedi S, Berloffa S: Aripiprazole augmentation in 39 adolescents with treatment refractory obsessivecompulsive disorder. J Clin Psychopharmacol 30:688-693, 2010.
28. Matsushita M, Egashira N, Harada S, et al.: Perospirone, a novel antipsychotic drug, inhibits marble-burying behavior via 5-HT1A receptor in mice: Implications for obsessive-compulsive disorder. J. Pharmacol. Sci 99:154-159, 2005. (Pubitemid 41524453)
29. Murphy TK, Mutch PJ, Reid JM, Edge PJ, Storch EA, BenTDon M, Yang M.: Open label aripiprazole in the treatment of youth with tic disorders. J Child Adolesc. Psychopharmacol. 19:441-447, 2009.
30. National Institute of Mental Health (NIMH): Abnormal Involuntary Movement Scale (AIMS). Psychopharmacol Bull 21:1077-1080, 1985.
31. OlfsonM, Crystal S,Gerhardt T,Huang C,Walkup JT, Scahill L: Patterns and correlates of tic disorders in privately and publicly insured youths. J Am Acad Child Adolesc Psychiatry 50:119-131, 2011.
32. Palumbo D, Maughan A, Kurlan R: Hypothesis III. Tourette syndrome is only one of several causes of a developmental basal ganglia syndrome. Arch Neurol 54:475-483, 1997. (Pubitemid 27172868)
33. Párraga HC, Párraga MI, Harris DK: Tic exacerbation and precipitation during atomoxetine treatment in two children with attentiondeficit hyperactivity disorder. Int J Psychiatry Med 37:415-424, 2007. (Pubitemid 351468864)
34. Pliszka SR, Crismon ML, Hughes CW, Corners CK, Emslie GJ, Jensen PS, McCracken JT, Swanson JM, Lopez M: Texas Consensus Conference of Pharmacotherapy of Childhood Attention Deficit Hyperactivity Disorder. J Am Acad Child Adolesc Psychiatry 45:642-657, 2006.
35. Pringsheim T, Steeves T: Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders. Cochrane Database Syst Rev 4:CD007990, 2011.
36. Robertson MM, Eapen V: Pharmacologic controversy of CNS stimulant in Gilles de la Tourette's syndrome. Clin Neuropharmacol 15:408-425, 1992.
37. Roessner V, Becker A, Banaschewski T, Rothenberger A: Psychopathological profile in children with chronic tic disorder and coexisting ADHD: Additive Effects. J Abnorm Child Psychol 35: 79-85, 2007. (Pubitemid 46399162)
38. Scahill L: Alpha-2 adrenergic agonists in children with inattention, hyperactivity and impulsiveness CNS Drugs 23 Suppl 1:43-49, 2009.
39. Scahill L, Chappell PB, Kim YS, Schultz RT, Katsovich L, Shepherd E, Arnsten AF, Cohen DJ, Leckman JF: A placebo-controlled study of guanfacine in the treatment of children with tic disorders and attention deficit hyperactivity disorder. Am J Psychiatry 158:1067-1074, 2001. (Pubitemid 32623110)
40. Schneider J, Gadow KD, Crowell JA, Sprafkin J: Anxiety in boys with attention-deficit/hyperactivity disorder with and without chronic multiple tic disorder. J Child Adolesc. Psychopharmacol. 19:737-748, 2009.
41. Sears J, Patel NC: Development of tics in a thirteen-year-old male following atomoxetine use. CNS Spectr 13:301-303, 2008. (Pubitemid 351656251)
42. Seo WS, Sung HM, Sea HS, Bai DS: Aripiprazole treatment of children and adolescents with Tourette disorder or chronic tic disorder. J Child Adolesc. Psychopharmacol. 18:197-205, 2008. (Pubitemid 351591440)
43. Shaffer D, Gould MS, Brasic J, Ambrosini P, Fisher P, Bird H, Aluwahlia S: A children's global assessment scale (CGAS). Arch Gen Psychiatry 40:1228-1231, 1983. (Pubitemid 13015019)
44. Singer HS: Treatment of tics and Tourette syndrome. Curr Treat Options Neurol 12:539-561, 2010.
45. Spencer TJ, Sallee FR, Gilbert DL, Dunn DW, McCracken JT, Coffey BJ, Budman CL, Ricardi RK, Leonard HL, Allen AJ, Milton DR, Feldman PD, Kelsey DK, Geller DA, Linder SL, Lewis DW, Winner PK, Kurlan RM, Mintz M: Atomoxetine treatment of ADHD in children with comorbid Tourette syndrome. J Atten Disord 11:470-481, 2008.
46. Stephens RJ, Sandor P: Aggressive behaviour in children with Tourette syndrome and comorbid attention-deficit hyperactivity disorder and obsessive-compulsive disorder. Can J Psychiatry 44:1036-1042, 1999. (Pubitemid 30062403)
47. Tourette's Syndrome Study Group: Treatment of ADHD in children with tic: A randomized controlled trial. Neurology 58:527-536, 2002.
48. Yoo HK, Choi SH, Park S, Wang HR, Hong JP, Kim CY: An openlabel study of the efficacy and tolerability of aripiprazole for children and adolescents with tic disorders. J Clin Psychiatry. 68: 1088-1093, 2007. (Pubitemid 47340331)
49. Yoo HK, Lee JS, Paik KW, Choi Sh, Yoon SJ, Kim JE, Hong JP: Open label study comparing the efficacy and tolerability of aripiprazole and haloperidol in the treatment of pediatric tic disorders. Eur Child Adolesc Psychiatry 20:127-135, 2011.