Meta-Analysis: Treatment of Attention-Deficit/Hyperactivity Disorder in Children With Comorbid Tic Disorders

Journal of the American Academy of Child and Adolescent Psychiatry

Volumn 48, Issue 9, 2009, Pages 884-893

  Bloch, Michael H ^a   Panza, Kaitlyn E ^a   Landeros Weisenberger, Angeli ^a   Leckman, James F ^a  

^a NONE

Author keywords

2 adrenergic agonists; attention deficit hyperactivity disorder; meta analysis; methylphenidate; tic disorders

Indexed keywords

ATOMOXETINE; CLONIDINE; DESIPRAMINE; DEXAMPHETAMINE; GUANFACINE; METHYLPHENIDATE; PLACEBO; SELEGILINE;

ATTENTION DEFICIT DISORDER; CLINICAL TRIAL; COMORBIDITY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DECREASED APPETITE; DIASTOLIC BLOOD PRESSURE; DISEASE EXACERBATION; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG DOSE ESCALATION; DRUG DOSE INCREASE; DRUG EFFICACY; EFFECT SIZE; GILLES DE LA TOURETTE SYNDROME; HUMAN; INSOMNIA; MAJOR CLINICAL STUDY; META ANALYSIS; MULTIPLE CYCLE TREATMENT; NAUSEA; PRIORITY JOURNAL; PULSE RATE; RANDOMIZED CONTROLLED TRIAL; REVIEW; SEDATION; SIDE EFFECT; SINGLE BLIND PROCEDURE; SYSTEMATIC REVIEW; TIC;

ADRENERGIC ALPHA-AGONISTS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CHILD; COMORBIDITY; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; HUMANS; METHYLPHENIDATE; PROPYLAMINES; PSYCHOTROPIC DRUGS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TIC DISORDERS; TOURETTE SYNDROME;

EID: 69949099185     PISSN: 08908567     EISSN: 15275418     Source Type: Journal    
DOI: 10.1097/CHI.0b013e3181b26e9f     Document Type: Review

References (54)

1. Physicians' Desk Reference. 61st ed. (2007), Thomson PDR, Montvale, NJ
2. Robertson M.M., and Eapen V. Pharmacologic controversy of CNS stimulants in Gilles de la Tourette's syndrome. Clin Neuropharmacol 15 (1992) 408-425
3. Khalifa N., and von Knorring A.L. Psychopathology in a Swedish population of school children with tic disorders. J Am Acad Child Adolesc Psychiatry 45 (2006) 1346-1353
4. Spencer T., Biederman J., Harding M., et al. Disentangling the overlap between Tourette's disorder and ADHD. J Child Psychol Psychiatry 39 (1998) 1037-1044
5. Sukhodolsky D.G., Scahill L., Zhang H., et al. Disruptive behavior in children with Tourette's syndrome: association with ADHD comorbidity, tic severity, and functional impairment. J Am Acad Child Adolesc Psychiatry 42 (2003) 98-105
6. Dulcan M. Practice parameters for the assessment and treatment of children, adolescents, and adults with attention-deficit/hyperactivity disorder. American Academy of Child and Adolescent Psychiatry. J Am Acad Child Adolesc Psychiatry 36 10 Suppl (1997) 85S-121S
7. Van der Oord S., Prins P.J., Oosterlaan J., and Emmelkamp P.M. Efficacy of methylphenidate, psychosocial treatments and their combination in school-aged children with ADHD: a meta-analysis. Clin Psychol Rev 28 (2008) 783-800
8. The MTA Cooperative Group. A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder. Multimodal Treatment Study of Children with ADHD. Arch Gen Psychiatry 56 (1999) 1073-1086
9. Faraone S.V., Biederman J., Spencer T.J., and Aleardi M. Comparing the efficacy of medications for ADHD using meta-analysis. MedGenMed 8 (2006) 4
10. Jadad A.R., Boyle M., Cunningham C., Kim M., and Schachar R. Treatment of attention-deficit/hyperactivity disorder. Evid Rep Technol Assess (Summ) (1999) i-viii 1-341.
11. Spencer T., Biederman J., Wilens T., Harding M., O'Donnell D., and Griffin S. Pharmacotherapy of attention-deficit hyperactivity disorder across the life cycle. J Am Acad Child Adolesc Psychiatry 35 (1996) 409-432
12. Golden G.S. The effect of central nervous system stimulants on Tourette syndrome. Ann Neurol 2 (1977) 69-70
13. Denckla M.B., Bemporad J.R., and MacKay M.C. Tics following methylphenidate administration. A report of 20 cases. JAMA 235 (1976) 1349-1351
14. Lowe T.L., Cohen D.J., Detlor J., Kremenitzer M.W., and Shaywitz B.A. Stimulant medications precipitate Tourette's syndrome. JAMA 247 (1982) 1168-1169
15. Madras B.K., Miller G.M., and Fischman A.J. The dopamine transporter and attention-deficit/hyperactivity disorder. Biol Psychiatry 57 (2005) 1397-1409
16. Albin R.L. Neurobiology of basal ganglia and Tourette syndrome: striatal and dopamine function. Adv Neurol 99 (2006) 99-106
17. Mink J.W. Basal ganglia dysfunction in Tourette's syndrome: a new hypothesis. Pediatr Neurol 25 (2001) 190-198
18. Leckman J.F. Tourette's syndrome. Lancet 360 (2002) 1577-1586
19. Shapiro A.K., and Shapiro E. Controlled study of pimozide vs. placebo in Tourette's syndrome. J Am Acad Child Psychiatry 23 (1984) 161-173
20. Nolan E.E., Gadow K.D., and Sverd J. Observations and ratings of tics in school settings. J Abnorm Child Psychol 22 (1994) 579-593
21. Leckman J.F., Riddle M.A., Hardin M.T., et al. The Yale Global Tic Severity Scale: initial testing of a clinician-rated scale of tic severity. J Am Acad Child Adolesc Psychiatry 28 (1989) 566-573
22. Walkup J.T., Rosenberg L.A., Brown J., and Singer H.S. The validity of instruments measuring tic severity in Tourette's syndrome. J Am Acad Child Adolesc Psychiatry 31 (1992) 472-477
23. Achenbach T.M., and Edelbrock C.S. Manual for the Child Behavior Checklist (1991), University of Vermont Department of Psychiatry, Burlington, VT
24. Werry J.S., Sprague R.L., and Cohen M.N. Conners' Teacher Rating Scale for use in drug studies with children-an empirical study. J Abnorm Child Psychol 3 (1975) 217-229
25. DuPaul G. Parent and teacher rating of ADHD symptoms: psychometric properties in a community-based sample. J Clin Child Psychol 20 (1991) 245-253
26. Pelham W.E., Milich R., Murphy D.A., and Murphy H.A. Normative data on the Iowa Conners teacher rating scale. J Clin Child Psychol 1989 (1989) 259-262
27. Goyette C.H., Conners C.K., and Ulrich R.F. Normative data on revised Conners Parent and Teacher Rating Scales. J Abnorm Child Psychol 6 (1978) 221-236
28. Elbourne D.R., Altman D.G., Higgins J.P., Curtin F., Worthington H.V., and Vail A. Meta-analyses involving cross-over trials: methodological issues. Int J Epidemiol 31 (2002) 140-149
29. Curtin F., Altman D.G., and Elbourne D. Meta-analysis combining parallel and cross-over clinical trials. I: Continuous outcomes. Stat Med 21 (2002) 2131-2144
30. Bloch M.H., Landeros-Weisenberger A., Dombrowski P., et al. Systematic review: pharmacological and behavioral treatment for trichotillomania. Biol Psychiatry 62 (2007) 839-846
31. Review Manager (RevMan) [computer program]. Version 4.2 for Windows. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration; 2003.
32. Egger M., Davey Smith G., Schneider M., and Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 315 (1997) 629-634
33. Castellanos F.X., Giedd J.N., Elia J., et al. Controlled stimulant treatment of ADHD and comorbid Tourette's syndrome: effects of stimulant and dose. J Am Acad Child Adolesc Psychiatry 36 (1997) 589-596
34. Gadow K.D., Nolan E.E., and Sverd J. Methylphenidate in hyperactive boys with comorbid tic disorder: II. Short-term behavioral effects in school settings. J Am Acad Child Adolesc Psychiatry 31 (1992) 462-471
35. Gadow K.D., Sverd J., Nolan E.E., Sprafkin J., and Schneider J. Immediate-release methylphenidate for ADHD in children with comorbid chronic multiple tic disorder. J Am Acad Child Adolesc Psychiatry 46 (2007) 840-848
36. Scahill L., Chappell P.B., Kim Y.S., et al. A placebo-controlled study of guanfacine in the treatment of children with tic disorders and attention deficit hyperactivity disorder. Am J Psychiatry 158 (2001) 1067-1074
37. Allen A.J., Kurlan R.M., Gilbert D.L., et al. Atomoxetine treatment in children and adolescents with ADHD and comorbid tic disorders. Neurology 65 (2005) 1941-1949
38. Tourette's Syndrome Study Group. Treatment of ADHD in children with tics: a randomized controlled trial. Neurology 58 (2002) 527-536
39. Singer H.S., Brown J., Quaskey S., Rosenberg L.A., Mellits E.D., and Denckla M.B. The treatment of attention-deficit hyperactivity disorder in Tourette's syndrome: a double-blind placebo-controlled study with clonidine and desipramine. Pediatrics 95 (1995) 74-81
40. Spencer T., Biederman J., Coffey B., et al. A double-blind comparison of desipramine and placebo in children and adolescents with chronic tic disorder and comorbid attention-deficit/hyperactivity disorder. Arch Gen Psychiatry 59 (2002) 649-656
41. Feigin A., Kurlan R., McDermott M.P., et al. A controlled trial of deprenyl in children with Tourette's syndrome and attention deficit hyperactivity disorder. Neurology 46 (1996) 965-968
42. Spencer T.J., Sallee F.R., Gilbert D.L., et al. Atomoxetine treatment of ADHD in children with comorbid Tourette syndrome. J Atten Disord 11 (2008) 470-481
43. Gadow K.D., Sverd J., Sprafkin J., Nolan E.E., and Ezor S.N. Efficacy of methylphenidate for attention-deficit hyperactivity disorder in children with tic disorder. Arch Gen Psychiatry 52 (1995) 444-455
44. Niederhofer H., Staffen W., and Mair A. A placebo-controlled study of lofexidine in the treatment of children with tic disorders and attention deficit hyperactivity disorder. J Psychopharmacol 17 (2003) 113-119
45. Bailey J. An exceptional case of plagiarism!. J Psychopharmacol 18 (2004) 291-292
46. Swanson J., Arnold L.E., Kraemer H., et al. Evidence, interpretation, and qualification from multiple reports of long-term outcomes in the Multimodal Treatment study of Children With ADHD (MTA): part I: executive summary. J Atten Disord 12 (2008) 4-14
47. Leckman J.F., Ort S., Caruso K.A., Anderson G.M., Riddle M.A., and Cohen D.J. Rebound phenomena in Tourette's syndrome after abrupt withdrawal of clonidine. Behavioral, cardiovascular, and neurochemical effects. Arch Gen Psychiatry 43 (1986) 1168-1176
48. Biederman J., Baldessarini R.J., Wright V., Knee D., Harmatz J.S., and Goldblatt A. A double-blind placebo controlled study of desipramine in the treatment ADD: II. Serum drug levels and cardiovascular findings. J Am Acad Child Adolesc Psychiatry 28 (1989) 903-911
49. Scahill L., Erenberg G., Berlin Jr. C.M., et al. Contemporary assessment and pharmacotherapy of Tourette syndrome. NeuroRx 3 (2006) 192-206
50. Wilens T.E., Spencer T.J., Swanson J.M., Connor D.F., and Cantwell D. Combining methylphenidate and clonidine: a clinically sound medication option. J Am Acad Child Adolesc Psychiatry 38 (1999) 614-619 discussion 619-622.
51. Daviss W.B., Patel N.C., Robb A.S., et al. Clonidine for attention-deficit/hyperactivity disorder: II. ECG changes and adverse events analysis. JAm Acad Child Adolesc Psychiatry 47 (2008) 189-198
52. Schachter H.M., Pham B., King J., Langford S., and Moher D. How efficacious and safe is short-acting methylphenidate for the treatment of attention-deficit disorder in children and adolescents? A meta-analysis. CMAJ 165 (2001) 1475-1488
53. Connor D.F., Fletcher K.E., and Swanson J.M. A meta-analysis of clonidine for symptoms of attention-deficit hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 38 (1999) 1551-1559
54. Cheng J.Y., Chen R.Y., Ko J.S., and Ng E.M. Efficacy and safety of atomoxetine for attention-deficit/hyperactivity disorder in children and adolescents-meta-analysis and meta-regression analysis. Psychopharmacology (Berl) 194 (2007) 197-209