메뉴 건너뛰기




Volumn 326, Issue 1-2, 2006, Pages 107-118

Formulation of an antispasmodic drug as a topical local anesthetic

Author keywords

Gel; Histopathology; Local anesthetic; Mebeverine HCl; Oral painful conditions

Indexed keywords

CETRIMIDE; HYDROXYPROPYLCELLULOSE; LIDOCAINE; MEBEVERINE; POLOXAMER; SPASMOLYTIC AGENT;

EID: 33751051538     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.07.028     Document Type: Article
Times cited : (39)

References (72)
  • 1
    • 0346458604 scopus 로고    scopus 로고
    • Development of in situ gelling and mucoadhesive mebeverine hydrochloride solution for rectal administration
    • Abdel-Hady S.S., Mortada N.D., Awad G.A.S., Zaki N.M., and Taha R.A. Development of in situ gelling and mucoadhesive mebeverine hydrochloride solution for rectal administration. Saudi Pharm. J. 11 (2003) 159-171
    • (2003) Saudi Pharm. J. , vol.11 , pp. 159-171
    • Abdel-Hady, S.S.1    Mortada, N.D.2    Awad, G.A.S.3    Zaki, N.M.4    Taha, R.A.5
  • 2
    • 0031597891 scopus 로고    scopus 로고
    • Buccal mucosa as a route for systemic drug delivery: a review
    • Amir H.S. Buccal mucosa as a route for systemic drug delivery: a review. J. Pharm. Pharm. Sci. 1 (1998) 15-30
    • (1998) J. Pharm. Pharm. Sci. , vol.1 , pp. 15-30
    • Amir, H.S.1
  • 3
    • 0032204171 scopus 로고    scopus 로고
    • Solute diffusion with hydrogels, mechanisms and models
    • Amsden B. Solute diffusion with hydrogels, mechanisms and models. Macromolecules 31 (1998) 8382-8395
    • (1998) Macromolecules , vol.31 , pp. 8382-8395
    • Amsden, B.1
  • 4
    • 0024371793 scopus 로고
    • Comparison of the effects of various transmucosal absorption promoters on buccal insulin delivery
    • Aungst B.J., and Rogers N.J. Comparison of the effects of various transmucosal absorption promoters on buccal insulin delivery. Int. J. Pharm. 53 (1989) 227-235
    • (1989) Int. J. Pharm. , vol.53 , pp. 227-235
    • Aungst, B.J.1    Rogers, N.J.2
  • 5
    • 0035834250 scopus 로고    scopus 로고
    • Incorporation of small quantities of surfactants as a way to improve the rheological and diffusional behavior of carbopol gels
    • Barreiro-Iglesias R., Alvarez-Lorenzo C., and Concheiro A. Incorporation of small quantities of surfactants as a way to improve the rheological and diffusional behavior of carbopol gels. J. Control. Release 77 (2001) 59-75
    • (2001) J. Control. Release , vol.77 , pp. 59-75
    • Barreiro-Iglesias, R.1    Alvarez-Lorenzo, C.2    Concheiro, A.3
  • 6
    • 0029761794 scopus 로고    scopus 로고
    • Controlled-release delivery system for the α-MSH analog Melanotan-I using Poloxamer 407
    • Bhardwaj R., and Blanchard J. Controlled-release delivery system for the α-MSH analog Melanotan-I using Poloxamer 407. J. Pharm. Sci. 85 (1996) 915-919
    • (1996) J. Pharm. Sci. , vol.85 , pp. 915-919
    • Bhardwaj, R.1    Blanchard, J.2
  • 7
    • 4444331868 scopus 로고    scopus 로고
    • Bioadhesive properties and rheology of polyether-modified poly(acrylic acid) hydrogels
    • Bromberg L., Temchenko M., Alakhov V., and Hatton T.A. Bioadhesive properties and rheology of polyether-modified poly(acrylic acid) hydrogels. Int. J. Pharm. 282 (2004) 45-60
    • (2004) Int. J. Pharm. , vol.282 , pp. 45-60
    • Bromberg, L.1    Temchenko, M.2    Alakhov, V.3    Hatton, T.A.4
  • 8
    • 0026552717 scopus 로고
    • Drug release from gel bases: a case for enthalpy-entropy compensation
    • Buckton G., and Tawburic S. Drug release from gel bases: a case for enthalpy-entropy compensation. J. Control. Release 20 (1992) 29-36
    • (1992) J. Control. Release , vol.20 , pp. 29-36
    • Buckton, G.1    Tawburic, S.2
  • 9
    • 0021963276 scopus 로고
    • Bioadhesive polymers as platforms for oral controlled drug delivery. Part 2. Synthesis and evaluation of some swelling, water insoluble bioadhesive polymers
    • Ch'ng H.S., Park H., Kelly P., and Robinson J.R. Bioadhesive polymers as platforms for oral controlled drug delivery. Part 2. Synthesis and evaluation of some swelling, water insoluble bioadhesive polymers. J. Pharm. Sci. 74 (1985) 399-411
    • (1985) J. Pharm. Sci. , vol.74 , pp. 399-411
    • Ch'ng, H.S.1    Park, H.2    Kelly, P.3    Robinson, J.R.4
  • 10
    • 0032550314 scopus 로고    scopus 로고
    • Development of in situ gelling and mucoadhesive acetaminophen liquid suppository
    • Choi H.-G., Jung J.-H., Ryu J.-M., Yoon S.-J., Oh Y.-K., and Kim C.-K. Development of in situ gelling and mucoadhesive acetaminophen liquid suppository. Int. J. Pharm. 165 (1998) 33-44
    • (1998) Int. J. Pharm. , vol.165 , pp. 33-44
    • Choi, H.-G.1    Jung, J.-H.2    Ryu, J.-M.3    Yoon, S.-J.4    Oh, Y.-K.5    Kim, C.-K.6
  • 11
    • 0001227382 scopus 로고
    • Physiological and clinical assessment of the effect of the musculotropic agent mebeverine on the human colon
    • Connell A.M. Physiological and clinical assessment of the effect of the musculotropic agent mebeverine on the human colon. Br. Med. J. 2 (1965) 848-851
    • (1965) Br. Med. J. , vol.2 , pp. 848-851
    • Connell, A.M.1
  • 13
    • 0023618487 scopus 로고
    • The action of mebeverine on mammalian non-myelinated nerve fibres
    • Den Hertog A., and Van den Akker J. The action of mebeverine on mammalian non-myelinated nerve fibres. Eur. J. Pharmacol. 139 (1987) 353-355
    • (1987) Eur. J. Pharmacol. , vol.139 , pp. 353-355
    • Den Hertog, A.1    Van den Akker, J.2
  • 14
    • 0031892629 scopus 로고    scopus 로고
    • In vitro evaluation of pluronic F-127 based controlled release ocular delivery systems for Pilocarpine
    • Desai S.D., and Blanchard J. In vitro evaluation of pluronic F-127 based controlled release ocular delivery systems for Pilocarpine. J. Pharm. Sci. 87 (1998) 226-230
    • (1998) J. Pharm. Sci. , vol.87 , pp. 226-230
    • Desai, S.D.1    Blanchard, J.2
  • 15
    • 23144451894 scopus 로고    scopus 로고
    • Preparation and evaluation of a novel buccal adhesive system
    • (article 35)
    • Desai K.G.H., and Kumar T.M.P. Preparation and evaluation of a novel buccal adhesive system. AAPS Pharm. Sci. Technol. 5 (2004) (article 35)
    • (2004) AAPS Pharm. Sci. Technol. , vol.5
    • Desai, K.G.H.1    Kumar, T.M.P.2
  • 16
    • 0029742606 scopus 로고    scopus 로고
    • Formulation and evaluation of epidermal growth factor in pluronic F-127 gel
    • DiBiase M.D., and Rhodes C.T. Formulation and evaluation of epidermal growth factor in pluronic F-127 gel. Drug Develop. Ind. Pharm. 22 (1996) 823-831
    • (1996) Drug Develop. Ind. Pharm. , vol.22 , pp. 823-831
    • DiBiase, M.D.1    Rhodes, C.T.2
  • 17
    • 0026077681 scopus 로고
    • Facile hydrolysis of mebeverine in vitro and in vivo: negligible circulating concentrations of the drug after oral administration
    • Dickinson R.G., Baker P.V., Franklin M.E., and Hooper W.D. Facile hydrolysis of mebeverine in vitro and in vivo: negligible circulating concentrations of the drug after oral administration. J. Pharm. Sci. 80 (1991) 952-957
    • (1991) J. Pharm. Sci. , vol.80 , pp. 952-957
    • Dickinson, R.G.1    Baker, P.V.2    Franklin, M.E.3    Hooper, W.D.4
  • 20
    • 0035349872 scopus 로고    scopus 로고
    • The anesthetic onset and duration of a new lidocaine/prilocaine gel intra-pocket anesthetic (Oraquix) for periodontal scaling/root planning
    • Friskopp J., Nilsson M., and Isacsson G. The anesthetic onset and duration of a new lidocaine/prilocaine gel intra-pocket anesthetic (Oraquix) for periodontal scaling/root planning. J. Clin. Periodontol. 28 (2001) 453-458
    • (2001) J. Clin. Periodontol. , vol.28 , pp. 453-458
    • Friskopp, J.1    Nilsson, M.2    Isacsson, G.3
  • 21
    • 0344845214 scopus 로고    scopus 로고
    • Ketoprofen: release from, permeation across and rheology of simple gel formulations that simulate increasing dryness
    • Gallagher S.J., Trottet L., and Heard C.M. Ketoprofen: release from, permeation across and rheology of simple gel formulations that simulate increasing dryness. Int. J. Pharm. 268 (2003) 37-45
    • (2003) Int. J. Pharm. , vol.268 , pp. 37-45
    • Gallagher, S.J.1    Trottet, L.2    Heard, C.M.3
  • 22
    • 0033803572 scopus 로고    scopus 로고
    • Comparison of two different formulations of mebeverine hydrochloride in irritable bowel syndrome
    • Gilbody J.S., Fletcher C.P., Hughes I.W., and Kidman S.P. Comparison of two different formulations of mebeverine hydrochloride in irritable bowel syndrome. Int. J. Clin. Pract. 54 (2000) 461-464
    • (2000) Int. J. Clin. Pract. , vol.54 , pp. 461-464
    • Gilbody, J.S.1    Fletcher, C.P.2    Hughes, I.W.3    Kidman, S.P.4
  • 23
    • 0021739215 scopus 로고
    • Bioadhesive intraoral release systems: design, testing and analysis
    • Gurny R., Meyer J.M., and Peppas N.A. Bioadhesive intraoral release systems: design, testing and analysis. Biomaterials 5 (1984) 336-340
    • (1984) Biomaterials , vol.5 , pp. 336-340
    • Gurny, R.1    Meyer, J.M.2    Peppas, N.A.3
  • 24
    • 0026545646 scopus 로고
    • Polyoxyethylene-polyoxypropylene block copolymer gels as sustained release vehicles for subcutaneous drug administration
    • Guzman M., Garcia F.F., Molpeceres J., and Aberturas M.R. Polyoxyethylene-polyoxypropylene block copolymer gels as sustained release vehicles for subcutaneous drug administration. Int. J. Pharm. 80 (1992) 119-127
    • (1992) Int. J. Pharm. , vol.80 , pp. 119-127
    • Guzman, M.1    Garcia, F.F.2    Molpeceres, J.3    Aberturas, M.R.4
  • 25
    • 0037384554 scopus 로고    scopus 로고
    • Limitations of the rheological mucoadhesion method: the effect of the choice of conditions and the rheological synergism parameter
    • Hägerström H., and Edsman K. Limitations of the rheological mucoadhesion method: the effect of the choice of conditions and the rheological synergism parameter. Eur. J. Pharm. Sci. 18 (2003) 349-357
    • (2003) Eur. J. Pharm. Sci. , vol.18 , pp. 349-357
    • Hägerström, H.1    Edsman, K.2
  • 27
    • 0036195510 scopus 로고    scopus 로고
    • Synthesis and characterization of self-assembling block copolymers containing bioadhesive end groups
    • Huang K., Lee B.P., Ingram D.R., and Messersmith P.B. Synthesis and characterization of self-assembling block copolymers containing bioadhesive end groups. Biomacromolecules 3 (2002) 397-406
    • (2002) Biomacromolecules , vol.3 , pp. 397-406
    • Huang, K.1    Lee, B.P.2    Ingram, D.R.3    Messersmith, P.B.4
  • 28
    • 0033793678 scopus 로고    scopus 로고
    • In vitro/in vivo studies on a buccal bioadhesive tablet formulation of carbamazepine
    • Ikinci G., Capan Y., Şenel S., Alaaddinoglu E., Dalkara T., and Hincal A.A. In vitro/in vivo studies on a buccal bioadhesive tablet formulation of carbamazepine. Pharmazie 55 (2000) 762-765
    • (2000) Pharmazie , vol.55 , pp. 762-765
    • Ikinci, G.1    Capan, Y.2    Şenel, S.3    Alaaddinoglu, E.4    Dalkara, T.5    Hincal, A.A.6
  • 29
    • 0028007260 scopus 로고
    • Clinical efficacy, safety and tolerance of mebeverine slow-release (200 mg) versus mebeverine tablets in patients with irritable bowel syndrome
    • Inauen W., and Halter F. Clinical efficacy, safety and tolerance of mebeverine slow-release (200 mg) versus mebeverine tablets in patients with irritable bowel syndrome. Drug Invest. 8 (1994) 234-240
    • (1994) Drug Invest. , vol.8 , pp. 234-240
    • Inauen, W.1    Halter, F.2
  • 30
    • 0142120522 scopus 로고    scopus 로고
    • Chlorhexidine-containing mucoadhesive polymeric compacts designed for use in the oral cavity: an examination of their physical properties, in vitro/in vivo drug release properties and clinical acceptability
    • Irwin C.R., McCullough K.C., and Jones D.S. Chlorhexidine-containing mucoadhesive polymeric compacts designed for use in the oral cavity: an examination of their physical properties, in vitro/in vivo drug release properties and clinical acceptability. Mater. Sci. Mater. Med. 14 (2003) 825-832
    • (2003) Mater. Sci. Mater. Med. , vol.14 , pp. 825-832
    • Irwin, C.R.1    McCullough, K.C.2    Jones, D.S.3
  • 31
    • 33751045368 scopus 로고    scopus 로고
    • Jacox, A., Carr, D.B., Payne, R., 1994. Clinical Practice Guideline number 9: Management of cancer pain, AHCPR publication 94-0592. US Department of Health and Human Services, Agency for Health Care Policy and Research, Rockville, MD.
  • 32
    • 0026619720 scopus 로고
    • Chronic pain copying measures: individuals versus composite scores
    • Jensen M.P., Turner J.A., and Romano J.M. Chronic pain copying measures: individuals versus composite scores. Pain 51 (1992) 273-280
    • (1992) Pain , vol.51 , pp. 273-280
    • Jensen, M.P.1    Turner, J.A.2    Romano, J.M.3
  • 34
    • 0030469411 scopus 로고    scopus 로고
    • Development and mechanical characterization of bioadhesive semi-solid polymeric systems containing tetracycline for the treatment of periodontal diseases
    • Jones D.S., Woolfson A.D., Djokic J., and Coulter W.A. Development and mechanical characterization of bioadhesive semi-solid polymeric systems containing tetracycline for the treatment of periodontal diseases. Pharm. Res. 13 (1996) 1732-1736
    • (1996) Pharm. Res. , vol.13 , pp. 1732-1736
    • Jones, D.S.1    Woolfson, A.D.2    Djokic, J.3    Coulter, W.A.4
  • 35
    • 0030955984 scopus 로고    scopus 로고
    • Textural, viscoelastic and mucoadhesive properties of pharmaceutical gels composed of cellulose polymers
    • Jones D.S., Woolfson A.D., and Brown A.F. Textural, viscoelastic and mucoadhesive properties of pharmaceutical gels composed of cellulose polymers. Int. J. Pharm. 151 (1997) 223-233
    • (1997) Int. J. Pharm. , vol.151 , pp. 223-233
    • Jones, D.S.1    Woolfson, A.D.2    Brown, A.F.3
  • 36
    • 0030913693 scopus 로고    scopus 로고
    • Textural analysis and flow rheometry of bioadhesive, antimicrobial oral gels
    • Jones D.S., Woolfson A.D., and Brown A.F. Textural analysis and flow rheometry of bioadhesive, antimicrobial oral gels. Pharm. Res. 14 (1997) 450-457
    • (1997) Pharm. Res. , vol.14 , pp. 450-457
    • Jones, D.S.1    Woolfson, A.D.2    Brown, A.F.3
  • 37
    • 0034601173 scopus 로고    scopus 로고
    • Design, characterization and preliminary clinical evaluation of a novel mucoadhesive topical formulation containing tetracycline for the treatment of periodontal disease
    • Jones D.S., Woolfson A.D., Brown A.F., Coulter W.A., McClelland C., and Irwin C.R. Design, characterization and preliminary clinical evaluation of a novel mucoadhesive topical formulation containing tetracycline for the treatment of periodontal disease. J. Control. Release 67 (2000) 357-368
    • (2000) J. Control. Release , vol.67 , pp. 357-368
    • Jones, D.S.1    Woolfson, A.D.2    Brown, A.F.3    Coulter, W.A.4    McClelland, C.5    Irwin, C.R.6
  • 38
    • 0004188123 scopus 로고    scopus 로고
    • Pharmaceutical Association and Pharmaceutical Press, London, United Kingdom pp. 140-142
    • Kibbe A.H. Handbook of Pharmaceutical Excipients. 3rd ed. (2000), Pharmaceutical Association and Pharmaceutical Press, London, United Kingdom pp. 140-142
    • (2000) Handbook of Pharmaceutical Excipients. 3rd ed.
    • Kibbe, A.H.1
  • 39
    • 0025322961 scopus 로고
    • Use of ion-exchange membranes to measure transfer free energies of charged local anesthetics: correlation to anesthetic potency
    • Kitagawa N., Kaminoh Y., Takasaki M., and Ueda I. Use of ion-exchange membranes to measure transfer free energies of charged local anesthetics: correlation to anesthetic potency. J. Pharm. Sci. 79 (1990) 344-348
    • (1990) J. Pharm. Sci. , vol.79 , pp. 344-348
    • Kitagawa, N.1    Kaminoh, Y.2    Takasaki, M.3    Ueda, I.4
  • 40
    • 0000218365 scopus 로고    scopus 로고
    • Gels and jellies
    • Swarbrick J., and Boylan J.C. (Eds), Marcel Dekker Inc., New York, Basel
    • Klech C.M. Gels and jellies. In: Swarbrick J., and Boylan J.C. (Eds). Encyclopedia of Pharmaceutical Technology vol. 6 (1999), Marcel Dekker Inc., New York, Basel 415-439
    • (1999) Encyclopedia of Pharmaceutical Technology , vol.6 , pp. 415-439
    • Klech, C.M.1
  • 43
    • 0024443559 scopus 로고
    • A double-blind placebo-controlled crossover study of mebeverine and mefenamic acid in the treatment of primary dysmenorrhea
    • Langrick A.F., Gunn A.D.G., Livesey H., and Whitehead A.M. A double-blind placebo-controlled crossover study of mebeverine and mefenamic acid in the treatment of primary dysmenorrhea. Br. J. Clin. Pract. 43 (1989) 317-321
    • (1989) Br. J. Clin. Pract. , vol.43 , pp. 317-321
    • Langrick, A.F.1    Gunn, A.D.G.2    Livesey, H.3    Whitehead, A.M.4
  • 44
    • 33751056426 scopus 로고    scopus 로고
    • Flavors and flavor modifiers
    • Swarbrick J., and Boylan J.C. (Eds), Marcel Dekker Inc., New York, Basel
    • Lipari J.M., and Reiland T.L. Flavors and flavor modifiers. In: Swarbrick J., and Boylan J.C. (Eds). Encyclopedia of Pharmaceutical Technology. 2nd ed. vol. 2 (2002), Marcel Dekker Inc., New York, Basel 1254-1263
    • (2002) Encyclopedia of Pharmaceutical Technology. 2nd ed. , vol.2 , pp. 1254-1263
    • Lipari, J.M.1    Reiland, T.L.2
  • 45
    • 0021347286 scopus 로고
    • The rheological properties of poloxamer vehicles
    • Miller S.C., and Drabik B.R. The rheological properties of poloxamer vehicles. Int. J. Pharm. 18 (1984) 269-276
    • (1984) Int. J. Pharm. , vol.18 , pp. 269-276
    • Miller, S.C.1    Drabik, B.R.2
  • 46
    • 0025606330 scopus 로고
    • The influence of additives on the cloud point, disintegration and dissolution of hydroxypropylmethylcellulose gels and matrix tablets
    • Mitchell K., Ford J.L., Armsrtong D.J., Eliott P.N.C., Rostron C., and Hogan J.E. The influence of additives on the cloud point, disintegration and dissolution of hydroxypropylmethylcellulose gels and matrix tablets. Int. J. Pharm. 66 (1990) 233-242
    • (1990) Int. J. Pharm. , vol.66 , pp. 233-242
    • Mitchell, K.1    Ford, J.L.2    Armsrtong, D.J.3    Eliott, P.N.C.4    Rostron, C.5    Hogan, J.E.6
  • 47
    • 0023600845 scopus 로고
    • Buccal/gingival drug delivery systems
    • Nagai T., and Konishi R. Buccal/gingival drug delivery systems. J. Control. Release 6 (1987) 353-360
    • (1987) J. Control. Release , vol.6 , pp. 353-360
    • Nagai, T.1    Konishi, R.2
  • 48
    • 33751030292 scopus 로고    scopus 로고
    • Solutions, emulsions, suspensions and extracts
    • Gennaro A.R. (Ed), Williams and Wilkins Inc., Lippincott, Philadelphia (Chapter 39)
    • Nairn J.G. Solutions, emulsions, suspensions and extracts. In: Gennaro A.R. (Ed). Remington: The Science and Practice of Pharmacy. 20th ed. (2000), Williams and Wilkins Inc., Lippincott, Philadelphia 745-747 (Chapter 39)
    • (2000) Remington: The Science and Practice of Pharmacy. 20th ed. , pp. 745-747
    • Nairn, J.G.1
  • 49
    • 0023407017 scopus 로고
    • Pluronic F-127 gel preparation as an artificial skin in the treatment of third-degree burns in pigs
    • Nalbandian R.M., Henry R.L., Balko K.W., Adams D.V., and Neuman N.R. Pluronic F-127 gel preparation as an artificial skin in the treatment of third-degree burns in pigs. J. Biomed. Mater. Res. 21 (1987) 1135-1148
    • (1987) J. Biomed. Mater. Res. , vol.21 , pp. 1135-1148
    • Nalbandian, R.M.1    Henry, R.L.2    Balko, K.W.3    Adams, D.V.4    Neuman, N.R.5
  • 50
    • 0031864961 scopus 로고    scopus 로고
    • A review of methods used to compare dissolution profile data
    • O'Hara T., Dunne A., Butler J., and Devane J. A review of methods used to compare dissolution profile data. PSTT 1 (1998) 214-223
    • (1998) PSTT , vol.1 , pp. 214-223
    • O'Hara, T.1    Dunne, A.2    Butler, J.3    Devane, J.4
  • 51
    • 0031948345 scopus 로고    scopus 로고
    • Controlled-release gel of ibuprofen and lidocaine in epidural use-analgesia and systemic absorption in pigs
    • Paavola A., Tarkkila P., Xu M., Wahlström T., Yliruusi J., and Rosenberg P. Controlled-release gel of ibuprofen and lidocaine in epidural use-analgesia and systemic absorption in pigs. Pharm. Res. 15 (1998) 482-487
    • (1998) Pharm. Res. , vol.15 , pp. 482-487
    • Paavola, A.1    Tarkkila, P.2    Xu, M.3    Wahlström, T.4    Yliruusi, J.5    Rosenberg, P.6
  • 52
    • 0021344079 scopus 로고
    • Bioadhesive polymers as platforms for oral-controlled drug delivery: method to study bioadhesion
    • Park K., and Robinson J.R. Bioadhesive polymers as platforms for oral-controlled drug delivery: method to study bioadhesion. Int. J. Pharm. 19 (1984) 107-127
    • (1984) Int. J. Pharm. , vol.19 , pp. 107-127
    • Park, K.1    Robinson, J.R.2
  • 53
    • 0033123016 scopus 로고    scopus 로고
    • Polymeric films as a vehicle for buccal delivery: swelling, mechanical and bioadhesive properties
    • Peh K.K., and Wong C.F. Polymeric films as a vehicle for buccal delivery: swelling, mechanical and bioadhesive properties. J. Pharm. Sci. 2 (1999) 53-61
    • (1999) J. Pharm. Sci. , vol.2 , pp. 53-61
    • Peh, K.K.1    Wong, C.F.2
  • 54
    • 0028361592 scopus 로고
    • Structural rheology of model ointment
    • Pena L.E., Lee B.L., and Sterns J.F. Structural rheology of model ointment. Pharm. Res. 11 (1994) 875-881
    • (1994) Pharm. Res. , vol.11 , pp. 875-881
    • Pena, L.E.1    Lee, B.L.2    Sterns, J.F.3
  • 55
    • 0021904208 scopus 로고
    • Analysis of Fickian and non-Fickian drug release from polymers
    • Peppas N.A. Analysis of Fickian and non-Fickian drug release from polymers. Pharm. Acta Helv. 60 (1985) 110-111
    • (1985) Pharm. Acta Helv. , vol.60 , pp. 110-111
    • Peppas, N.A.1
  • 57
    • 0035234191 scopus 로고    scopus 로고
    • Comparison of topical EMLA 5% oral adhesive to benzocaine 20% on the pain experienced during palatal anesthetic infiltration in children
    • Primosch R.E., and Rolland-Asensi G. Comparison of topical EMLA 5% oral adhesive to benzocaine 20% on the pain experienced during palatal anesthetic infiltration in children. Pediatr. Dent. 23 (2001) 11-14
    • (2001) Pediatr. Dent. , vol.23 , pp. 11-14
    • Primosch, R.E.1    Rolland-Asensi, G.2
  • 59
    • 0033044064 scopus 로고    scopus 로고
    • Rheological characterization of hydroxypropylcellulose gels
    • Ramachandran S., Chen S., and Etzler F. Rheological characterization of hydroxypropylcellulose gels. Drug Develop. Ind. Pharm. 25 (1999) 153-161
    • (1999) Drug Develop. Ind. Pharm. , vol.25 , pp. 153-161
    • Ramachandran, S.1    Chen, S.2    Etzler, F.3
  • 60
    • 0018952259 scopus 로고
    • Comparison of various treatments for irritable bowel syndrome
    • Ritchie J.A., and Truelove S.C. Comparison of various treatments for irritable bowel syndrome. Br. Med. J. 231 (1980) 1317-1319
    • (1980) Br. Med. J. , vol.231 , pp. 1317-1319
    • Ritchie, J.A.1    Truelove, S.C.2
  • 61
    • 0034665819 scopus 로고    scopus 로고
    • Non-ionic cellulose ethers as potential drug delivery systems for periodontal anesthesia
    • Scherlund M., Brodin A., and Malmesten M. Non-ionic cellulose ethers as potential drug delivery systems for periodontal anesthesia. J. Colloid Interf. Sci. 229 (2000) 365-374
    • (2000) J. Colloid Interf. Sci. , vol.229 , pp. 365-374
    • Scherlund, M.1    Brodin, A.2    Malmesten, M.3
  • 62
    • 0032529057 scopus 로고    scopus 로고
    • Histological and bioadhesion studies on buccal bioadhesive tablets containing a penetration enhancer sodium glycodeoxycholate
    • Şenel S., Capan Y., Sargon M.F., Giray C.B., and Hincal A.A. Histological and bioadhesion studies on buccal bioadhesive tablets containing a penetration enhancer sodium glycodeoxycholate. Int. J. Pharm. 170 (1998) 239-245
    • (1998) Int. J. Pharm. , vol.170 , pp. 239-245
    • Şenel, S.1    Capan, Y.2    Sargon, M.F.3    Giray, C.B.4    Hincal, A.A.5
  • 63
    • 0034028545 scopus 로고    scopus 로고
    • Mucoadhesive and physicochemical characterization of carbopol-poloxamer gels containing triamcinolone acetonide
    • Shin S.-C., Kim J.-Y., and Oh I.-J. Mucoadhesive and physicochemical characterization of carbopol-poloxamer gels containing triamcinolone acetonide. Drug Develop. Ind. Pharm. 26 (2000) 307-312
    • (2000) Drug Develop. Ind. Pharm. , vol.26 , pp. 307-312
    • Shin, S.-C.1    Kim, J.-Y.2    Oh, I.-J.3
  • 64
    • 0022179911 scopus 로고
    • Effects of surfactants on the permeability of canine oral mucosa in vitro
    • Siegel I.A., and Gordon H.P. Effects of surfactants on the permeability of canine oral mucosa in vitro. Toxicol. Lett. 26 (1985) 153-157
    • (1985) Toxicol. Lett. , vol.26 , pp. 153-157
    • Siegel, I.A.1    Gordon, H.P.2
  • 65
    • 0028209127 scopus 로고
    • The effect of enhancers on the buccal absorption of hybrid (BDBB) alpha-interferon
    • Steward A., Bayley D.L., and Howes C. The effect of enhancers on the buccal absorption of hybrid (BDBB) alpha-interferon. Int. J. Pharm. 104 (1994) 145-149
    • (1994) Int. J. Pharm. , vol.104 , pp. 145-149
    • Steward, A.1    Bayley, D.L.2    Howes, C.3
  • 67
    • 33751040596 scopus 로고    scopus 로고
    • Tapolsky, W., Gilles, H., Osborne, D., 2000. Pharmaceutical gel preparation applicable to mucosal surfaces and body tissues. US Patent 6,103,266.
  • 68
    • 33751040075 scopus 로고    scopus 로고
    • Ukai, K., Harada, T., 2003. Medicinal comparisons with relieved bitterness. US Patent 6,576,677.
  • 69
    • 0028804255 scopus 로고
    • A double blind, crossover comparison study of the safety and efficacy of mebeverine with mebeverine sustained-release in the treatment of irritable bowel syndrome
    • Van Outryve M., Mayeur S., and Meeus M.A. A double blind, crossover comparison study of the safety and efficacy of mebeverine with mebeverine sustained-release in the treatment of irritable bowel syndrome. J. Clin. Pharm. Ther. 20 (1995) 277-282
    • (1995) J. Clin. Pharm. Ther. , vol.20 , pp. 277-282
    • Van Outryve, M.1    Mayeur, S.2    Meeus, M.A.3
  • 70
    • 0038437838 scopus 로고
    • Predicting stability in rheologically modified systems
    • Laba D. (Ed), Marcel Dekker Inc., New York (Chapter 9)
    • Vaughan D. Predicting stability in rheologically modified systems. In: Laba D. (Ed). Rheological Properties of Cosmetics and Toiletries (1993), Marcel Dekker Inc., New York 371-401 (Chapter 9)
    • (1993) Rheological Properties of Cosmetics and Toiletries , pp. 371-401
    • Vaughan, D.1
  • 71
    • 0035845756 scopus 로고    scopus 로고
    • Effect of sodium chloride on the gelation temperature, gel strength and bioadhesive force of poloxamer gels containing diclofenac sodium
    • Yong C.H., Choi J.S., Quan Q.-Z., Rhee J.-D., Kim C.-K., Lim S.-J., Kim K.-M., Oh P.-S., and Choi H.-G. Effect of sodium chloride on the gelation temperature, gel strength and bioadhesive force of poloxamer gels containing diclofenac sodium. Int. J. Pharm. 226 (2001) 195-205
    • (2001) Int. J. Pharm. , vol.226 , pp. 195-205
    • Yong, C.H.1    Choi, J.S.2    Quan, Q.-Z.3    Rhee, J.-D.4    Kim, C.-K.5    Lim, S.-J.6    Kim, K.-M.7    Oh, P.-S.8    Choi, H.-G.9
  • 72
    • 0017551109 scopus 로고
    • A new desensitizing dentifrice: preliminary report
    • Zinner D.D., Duany L.F., and Lutz H.J. A new desensitizing dentifrice: preliminary report. J. Am. Dent. Assoc. 95 (1977) 982-990
    • (1977) J. Am. Dent. Assoc. , vol.95 , pp. 982-990
    • Zinner, D.D.1    Duany, L.F.2    Lutz, H.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.