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Volumn 109, Issue 16, 2012, Pages 6271-6276

Schizophrenia risk polymorphisms in the TCF4 gene interact with smoking in the modulation of auditory sensory gating

(26)  Quednow, Boris B a,b   Brinkmeyer, Jur̈gen c,d   Mobascher, Arian c,d,e   Nothnagel, Michael f   Musso, Francesco c   Grun̈der, Gerhard g   Savary, Noah a   Petrovsky, Nadine b   Frommann, Ingo b   Lennertz, Leonhard b   Spreckelmeyer, Katja N g   Wienker, Thomas F b   Dahmen, Norbert e   Thuerauf, Norbert h   Clepce, Marion h   Kiefer, Falk i   Majic, Tomislav j   Mos̈sner, Rainald a   Maier, Wolfgang b,k   Gallinat, Jur̈gen j   more..


Author keywords

Gene environment interaction; Intermediate phenotype; Nicotine; Single nucleotide polymorphism

Indexed keywords

CARBON MONOXIDE; COTININE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR 4; UNCLASSIFIED DRUG;

EID: 84859931472     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1118051109     Document Type: Article
Times cited : (47)

References (81)
  • 1
    • 80053384370 scopus 로고    scopus 로고
    • Genome-wide association study identifies five new schizophrenia loci
    • Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium
    • Ripke S, et al.; Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium (2011) Genome-wide association study identifies five new schizophrenia loci. Nat Genet 43:969-976.
    • (2011) Nat Genet , vol.43 , pp. 969-976
    • Ripke, S.1
  • 2
    • 68449090594 scopus 로고    scopus 로고
    • Common variants conferring risk of schizophrenia
    • Genetic Risk and Outcome in Psychosis (GROUP)
    • Stefansson H, et al.; Genetic Risk and Outcome in Psychosis (GROUP) (2009) Common variants conferring risk of schizophrenia. Nature 460:744-747.
    • (2009) Nature , vol.460 , pp. 744-747
    • Stefansson, H.1
  • 3
    • 80053159517 scopus 로고    scopus 로고
    • Common variants at VRK2 and TCF4 conferring risk of schizophrenia
    • Irish Schizophrenia Genomics Consortium; GROUP; Wellcome Trust Case Control Consortium 2
    • Steinberg S, et al.; Irish Schizophrenia Genomics Consortium; GROUP; Wellcome Trust Case Control Consortium 2 (2011) Common variants at VRK2 and TCF4 conferring risk of schizophrenia. Hum Mol Genet 20:4076-4081.
    • (2011) Hum Mol Genet , vol.20 , pp. 4076-4081
    • Steinberg, S.1
  • 5
    • 0037968010 scopus 로고    scopus 로고
    • Basic helix-loop-helix factors in cortical development
    • DOI 10.1016/S0896-6273(03)00365-9
    • Ross SE, Greenberg ME, Stiles CD (2003) Basic helix-loop-helix factors in cortical development. Neuron 39:13-25. (Pubitemid 36830945)
    • (2003) Neuron , vol.39 , Issue.1 , pp. 13-25
    • Ross, S.E.1    Greenberg, M.E.2    Stiles, C.D.3
  • 6
    • 63749123537 scopus 로고    scopus 로고
    • Mutational, functional, and expression studies of the TCF4 gene in Pitt-Hopkins syndrome
    • de Pontual L, et al. (2009) Mutational, functional, and expression studies of the TCF4 gene in Pitt-Hopkins syndrome. Hum Mutat 30:669-676.
    • (2009) Hum Mutat , vol.30 , pp. 669-676
    • De Pontual, L.1
  • 7
    • 80052481818 scopus 로고    scopus 로고
    • Association between TCF4 and schizophrenia does not exert its effect by common nonsynonymous variation or by influencing cis-acting regulation of mRNA expression in adult human brain
    • Williams HJ, et al. (2011) Association between TCF4 and schizophrenia does not exert its effect by common nonsynonymous variation or by influencing cis-acting regulation of mRNA expression in adult human brain. Am J Med Genet B Neuropsychiatr Genet 156B:781-784.
    • (2011) Am J Med Genet B Neuropsychiatr Genet , vol.156 B , pp. 781-784
    • Williams, H.J.1
  • 8
    • 77953613107 scopus 로고    scopus 로고
    • Cognitive and sensorimotor gating impairments in transgenic mice overexpressing the schizophrenia susceptibility gene Tcf4 in the brain
    • Brzózka MM, Radyushkin K, Wichert SP, Ehrenreich H, Rossner MJ (2010) Cognitive and sensorimotor gating impairments in transgenic mice overexpressing the schizophrenia susceptibility gene Tcf4 in the brain. Biol Psychiatry 68:33-40.
    • (2010) Biol Psychiatry , vol.68 , pp. 33-40
    • Brzózka, M.M.1    Radyushkin, K.2    Wichert, S.P.3    Ehrenreich, H.4    Rossner, M.J.5
  • 9
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: Etymology and strategic intentions
    • DOI 10.1176/appi.ajp.160.4.636
    • Gottesman II, Gould TD (2003) The endophenotype concept in psychiatry: Etymology and strategic intentions. Am J Psychiatry 160:636-645. (Pubitemid 41079594)
    • (2003) American Journal of Psychiatry , vol.160 , Issue.4 , pp. 636-645
    • Gottesman, I.I.1    Gould, T.D.2
  • 10
    • 79955766426 scopus 로고    scopus 로고
    • The schizophrenia risk allele C of the TCF4 rs9960767 polymorphism disrupts sensorimotor gating in schizophrenia spectrum and healthy volunteers
    • Quednow BB, et al. (2011) The schizophrenia risk allele C of the TCF4 rs9960767 polymorphism disrupts sensorimotor gating in schizophrenia spectrum and healthy volunteers. J Neurosci 31:6684-6691.
    • (2011) J Neurosci , vol.31 , pp. 6684-6691
    • Quednow, B.B.1
  • 11
    • 0020575515 scopus 로고
    • Neurophysiological evidence for a defect in inhibitory pathways in schizophrenia: Comparison of medicated and drug-free patients
    • Freedman R, Adler LE, Waldo MC, Pachtman E, Franks RD (1983) Neurophysiological evidence for a defect in inhibitory pathways in schizophrenia: Comparison of medicated and drug-free patients. Biol Psychiatry 18:537-551. (Pubitemid 13135325)
    • (1983) Biological Psychiatry , vol.18 , Issue.5 , pp. 537-551
    • Freedman, R.1    Adler, L.E.2    Waldo, M.C.3
  • 14
    • 78650951399 scopus 로고    scopus 로고
    • Source localization of sensory gating: A combined EEG and fMRI study in healthy volunteers
    • Bak N, Glenthoj BY, Rostrup E, Larsson HB, Oranje B (2011) Source localization of sensory gating: A combined EEG and fMRI study in healthy volunteers. Neuroimage 54:2711-2718.
    • (2011) Neuroimage , vol.54 , pp. 2711-2718
    • Bak, N.1    Glenthoj, B.Y.2    Rostrup, E.3    Larsson, H.B.4    Oranje, B.5
  • 15
    • 3142657146 scopus 로고    scopus 로고
    • Preattentional and attentional cognitive deficits as targets for treating schizophrenia
    • Braff DL, Light GA (2004) Preattentional and attentional cognitive deficits as targets for treating schizophrenia. Psychopharmacology (Berl) 174:75-85. (Pubitemid 38925093)
    • (2004) Psychopharmacology , vol.174 , Issue.1 , pp. 75-85
    • Braff, D.L.1    Light, G.A.2
  • 16
    • 70349113111 scopus 로고    scopus 로고
    • P50, N100, and P200 sensory gating: Relationships with behavioral inhibition, attention, and working memory
    • Lijffijt M, et al. (2009) P50, N100, and P200 sensory gating: Relationships with behavioral inhibition, attention, and working memory. Psychophysiology 46: 1059-1068.
    • (2009) Psychophysiology , vol.46 , pp. 1059-1068
    • Lijffijt, M.1
  • 18
    • 72449146250 scopus 로고    scopus 로고
    • P50 sensory gating is related to performance on select tasks of cognitive inhibition
    • Yadon CA, Bugg JM, Kisley MA, Davalos DB (2009) P50 sensory gating is related to performance on select tasks of cognitive inhibition. Cogn Affect Behav Neurosci 9: 448-458.
    • (2009) Cogn Affect Behav Neurosci , vol.9 , pp. 448-458
    • Yadon, C.A.1    Bugg, J.M.2    Kisley, M.A.3    Davalos, D.B.4
  • 19
    • 74249084512 scopus 로고    scopus 로고
    • P50 gating deficit in Alzheimer dementia correlates to frontal neuropsychological function
    • Thomas C, et al. (2010) P50 gating deficit in Alzheimer dementia correlates to frontal neuropsychological function. Neurobiol Aging 31:416-424.
    • (2010) Neurobiol Aging , vol.31 , pp. 416-424
    • Thomas, C.1
  • 20
    • 0019995306 scopus 로고
    • Neurophysiological evidence for a defect in neuronal mechanisms involved in sensory gating in schizophrenia
    • Adler LE, et al. (1982) Neurophysiological evidence for a defect in neuronal mechanisms involved in sensory gating in schizophrenia. Biol Psychiatry 17:639-654. (Pubitemid 12090209)
    • (1982) Biological Psychiatry , vol.17 , Issue.6 , pp. 639-654
    • Adler, L.E.1    Pachtman, E.2    Franks, R.D.3
  • 21
    • 0030926304 scopus 로고    scopus 로고
    • P50 suppression among schizophrenia and normal comparison subjects: A methodological analysis
    • DOI 10.1016/S0006-3223(96)00208-9
    • Clementz BA, Geyer MA, Braff DL (1997) P50 suppression among schizophrenia and normal comparison subjects: A methodological analysis. Biol Psychiatry 41:1035-1044. (Pubitemid 27225991)
    • (1997) Biological Psychiatry , vol.41 , Issue.10 , pp. 1035-1044
    • Clementz, B.A.1    Geyer, M.A.2    Braff, D.L.3
  • 22
    • 0032500564 scopus 로고    scopus 로고
    • P50 abnormalities in schizophrenia: Relationship to clinical and neuropsychological indices of attention
    • DOI 10.1016/S0920-9964(98)00075-9, PII S0920996498000759
    • Erwin RJ, Turetsky BI, Moberg P, Gur RC, Gur RE (1998) P50 abnormalities in schizophrenia: Relationship to clinical and neuropsychological indices of attention. Schizophr Res 33:157-167. (Pubitemid 28446540)
    • (1998) Schizophrenia Research , vol.33 , Issue.3 , pp. 157-167
    • Erwin, R.J.1    Turetsky, B.I.2    Moberg, P.3    Gur, R.C.4    Gur, R.E.5
  • 24
    • 0026018702 scopus 로고
    • Gating of auditory response in schizophrenics and normal controls. Effects of recording site and stimulation interval on the P50 wave
    • Nagamoto HT, Adler LE, Waldo MC, Griffith J, Freedman R (1991) Gating of auditory response in schizophrenics and normal controls. Effects of recording site and stimulation interval on the P50 wave. Schizophr Res 4:31-40.
    • (1991) Schizophr Res , vol.4 , pp. 31-40
    • Nagamoto, H.T.1    Adler, L.E.2    Waldo, M.C.3    Griffith, J.4    Freedman, R.5
  • 25
    • 0031766704 scopus 로고    scopus 로고
    • P50 suppression in recent-onset schizophrenia: Clinical correlates and risperidone effects
    • DOI 10.1037//0021-843X.107.4.691
    • Yee CM, Nuechterlein KH, Morris SE, White PM (1998) P50 suppression in recent-onset schizophrenia: Clinical correlates and risperidone effects. J AbnormPsychol 107:691-698. (Pubitemid 28527584)
    • (1998) Journal of Abnormal Psychology , vol.107 , Issue.4 , pp. 691-698
    • Yee-Bradbury, C.M.1    Nuechterlein, K.H.2    Morris, S.E.3    White, P.M.4
  • 27
    • 0028062088 scopus 로고
    • Sensory gating deviance in schizophrenia in the context of task related effects
    • DOI 10.1016/0167-8760(84)90010-2
    • Guterman Y, Josiassen RC (1994) Sensory gating deviance in schizophrenia in the context of task related effects. Int J Psychophysiol 18:1-12. (Pubitemid 24344511)
    • (1994) International Journal of Psychophysiology , vol.18 , Issue.1 , pp. 1-12
    • Guterman, Y.1
  • 29
    • 0025213410 scopus 로고
    • Sensory gating in normals and schizophrenics: A failure to find strong P50 suppression in normals
    • DOI 10.1016/0006-3223(90)90419-3
    • Kathmann N, Engel RR (1990) Sensory gating in normals and schizophrenics: A failure to find strong P50 suppression in normals. Biol Psychiatry 27:1216-1226. (Pubitemid 20157935)
    • (1990) Biological Psychiatry , vol.27 , Issue.11 , pp. 1216-1226
    • Kathmann, N.1    Engel, R.R.2
  • 30
    • 4344698417 scopus 로고    scopus 로고
    • Meta-analysis of the P300 and P50 waveforms in schizophrenia
    • DOI 10.1016/j.schres.2004.01.004, PII S0920996404000349
    • Bramon E, Rabe-Hesketh S, Sham P, Murray RM, Frangou S (2004) Meta-analysis of the P300 and P50 waveforms in schizophrenia. Schizophr Res 70:315-329. (Pubitemid 39141109)
    • (2004) Schizophrenia Research , vol.70 , Issue.2-3 , pp. 315-329
    • Bramon, E.1    Rabe-Hesketh, S.2    Sham, P.3    Murray, R.M.4    Frangou, S.5
  • 31
    • 36049050070 scopus 로고    scopus 로고
    • A meta-analysis of P50 studies in patients with schizophrenia and relatives: Differences in methodology between research groups
    • DOI 10.1016/j.schres.2007.04.028, PII S0920996407001806
    • de Wilde OM, Bour LJ, Dingemans PM, Koelman JH, Linszen DH (2007) A meta-analysis of P50 studies in patients with schizophrenia and relatives: Differences in methodology between research groups. Schizophr Res 97:137-151. (Pubitemid 350088378)
    • (2007) Schizophrenia Research , vol.97 , Issue.1-3 , pp. 137-151
    • De Wilde, O.M.1    Bour, L.J.2    Dingemans, P.M.3    Koelman, J.H.T.M.4    Linszen, D.H.5
  • 32
    • 39649111304 scopus 로고    scopus 로고
    • P50 sensory gating ratios in schizophrenics and controls: A review and data analysis
    • Patterson JV, et al. (2008) P50 sensory gating ratios in schizophrenics and controls: A review and data analysis. Psychiatry Res 158:226-247.
    • (2008) Psychiatry Res , vol.158 , pp. 226-247
    • Patterson, J.V.1
  • 33
    • 33845307916 scopus 로고    scopus 로고
    • Genetic and environmental influences on sensory gating of mid-latency auditory evoked responses: A twin study
    • DOI 10.1016/j.schres.2006.08.009, PII S0920996406003598
    • Anokhin AP, Vedeniapin AB, Heath AC, Korzyukov O, Boutros NN (2007) Genetic and environmental influences on sensory gating of mid-latency auditory evoked responses: A twin study. Schizophr Res 89:312-319. (Pubitemid 44881286)
    • (2007) Schizophrenia Research , vol.89 , Issue.1-3 , pp. 312-319
    • Anokhin, A.P.1    Vedeniapin, A.B.2    Heath, A.C.3    Korzyukov, O.4    Boutros, N.N.5
  • 35
    • 0029973406 scopus 로고    scopus 로고
    • Heritability of inhibitory gating of the p50 auditory-evoked potential in monozygotic and dizygotic twins
    • Young DA, Waldo M, Rutledge JH, 3rd, Freedman R (1996) Heritability of inhibitory gating of the P50 auditory-evoked potential in monozygotic and dizygotic twins. Neuropsychobiology 33:113-117. (Pubitemid 26156185)
    • (1996) Neuropsychobiology , vol.33 , Issue.3 , pp. 113-117
    • Young, D.A.1    Waldo, M.2    Rutledge III, J.H.3    Freedman, R.4
  • 36
    • 0031791660 scopus 로고    scopus 로고
    • Poor P50 suppression among schizophrenia patients and their first- degree biological relatives
    • Clementz BA, Geyer MA, Braff DL (1998) Poor P50 suppression among schizophrenia patients and their first-degree biological relatives. Am J Psychiatry 155:1691-1694. (Pubitemid 28547492)
    • (1998) American Journal of Psychiatry , vol.155 , Issue.12 , pp. 1691-1694
    • Clementz, B.A.1    Geyer, M.A.2    Braff, D.L.3
  • 37
    • 0021234214 scopus 로고
    • Deficits in sensory gating in schizophrenic patients and their relatives. Evidence obtained with auditory evoked responses
    • Siegel C, Waldo M, Mizner G, Adler LE, Freedman R (1984) Deficits in sensory gating in schizophrenic patients and their relatives. Evidence obtained with auditory evoked responses. Arch Gen Psychiatry 41:607-612. (Pubitemid 14111389)
    • (1984) Archives of General Psychiatry , vol.41 , Issue.6 , pp. 607-612
    • Siegel, C.1    Waldo, M.2    Mizner, G.3
  • 38
    • 0033961241 scopus 로고    scopus 로고
    • Sensory gating deficits assessed by the P50 event-related potential in subjects with schizotypal personality disorder
    • Cadenhead KS, Light GA, Geyer MA, Braff DL (2000) Sensory gating deficits assessed by the P50 event-related potential in subjects with schizotypal personality disorder. Am J Psychiatry 157:55-59. (Pubitemid 30027421)
    • (2000) American Journal of Psychiatry , vol.157 , Issue.1 , pp. 55-59
    • Cadenhead, K.S.1    Light, G.A.2    Geyer, M.A.3    Braff, D.L.4
  • 39
    • 48749093404 scopus 로고    scopus 로고
    • Sensory gating in schizophrenia: P50 and N100 gating in antipsychotic-free subjects at risk, first-episode, and chronic patients
    • Brockhaus-Dumke A, et al. (2008) Sensory gating in schizophrenia: P50 and N100 gating in antipsychotic-free subjects at risk, first-episode, and chronic patients. Biol Psychiatry 64:376-384.
    • (2008) Biol Psychiatry , vol.64 , pp. 376-384
    • Brockhaus-Dumke, A.1
  • 40
    • 20444386499 scopus 로고    scopus 로고
    • P50 suppression in individuals at risk for schizophrenia: The convergence of clinical, familial, and vulnerability marker risk assessment
    • DOI 10.1016/j.biopsych.2005.03.003, PII S000632230500243X
    • Cadenhead KS, Light GA, Shafer KM, Braff DL (2005) P50 suppression in individuals at risk for schizophrenia: The convergence of clinical, familial, and vulnerability marker risk assessment. Biol Psychiatry 57:1504-1509. (Pubitemid 40805379)
    • (2005) Biological Psychiatry , vol.57 , Issue.12 , pp. 1504-1509
    • Cadenhead, K.S.1    Light, G.A.2    Shafer, K.M.3    Braff, D.L.4
  • 42
    • 34548478801 scopus 로고    scopus 로고
    • 158Met Polymorphism on the P50 Gating Endophenotype in Schizophrenia
    • DOI 10.1016/j.biopsych.2006.11.030, PII S0006322306015484, Molecular Mechanisms, Brain Development, and Novel Treatment Mechanisms for Schizophrenia
    • Lu BY, et al. (2007) Effect of catechol O-methyltransferase val(158)met polymorphism on the p50 gating endophenotype in schizophrenia. Biol Psychiatry 62:822-825. (Pubitemid 47374646)
    • (2007) Biological Psychiatry , vol.62 , Issue.7 , pp. 822-825
    • Lu, B.Y.1    Martin, K.E.2    Edgar, J.C.3    Smith, A.K.4    Lewis, S.F.5    Escamilla, M.A.6    Miller, G.A.7    Canive, J.M.8
  • 43
    • 79551624141 scopus 로고    scopus 로고
    • COMT Val108/158Met genotype modulates human sensory gating
    • Majic T, et al. (2011) COMT Val108/158Met genotype modulates human sensory gating. Neuroimage 55:818-824.
    • (2011) Neuroimage , vol.55 , pp. 818-824
    • Majic, T.1
  • 44
    • 79952819313 scopus 로고    scopus 로고
    • Do COMT, BDNF and NRG1 polymorphisms influence P50 sensory gating in psychosis?
    • Shaikh M, et al. (2011) Do COMT, BDNF and NRG1 polymorphisms influence P50 sensory gating in psychosis? Psychol Med 41:263-276.
    • (2011) Psychol Med , vol.41 , pp. 263-276
    • Shaikh, M.1
  • 45
    • 80051953863 scopus 로고    scopus 로고
    • Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia
    • Greenwood TA, et al. (2011) Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. Am J Psychiatry 168:930-946.
    • (2011) Am J Psychiatry , vol.168 , pp. 930-946
    • Greenwood, T.A.1
  • 46
    • 79951612327 scopus 로고    scopus 로고
    • Gating in schizophrenia: From genes to cognition (to real world function?)
    • Braff DL (2011) Gating in schizophrenia: From genes to cognition (to real world function?). Biol Psychiatry 69:395-396.
    • (2011) Biol Psychiatry , vol.69 , pp. 395-396
    • Braff, D.L.1
  • 47
    • 34247615035 scopus 로고    scopus 로고
    • Prepulse Inhibition and P50 Suppression Are Both Deficient but not Correlated in Schizophrenia Patients
    • DOI 10.1016/j.biopsych.2006.08.015, PII S0006322306010456, Multiple Genotypes and Brain Development in Schizophrenia
    • Braff DL, Light GA, Swerdlow NR (2007) Prepulse inhibition and P50 suppression are both deficient but not correlated in schizophrenia patients. Biol Psychiatry 61: 1204-1207. (Pubitemid 46669461)
    • (2007) Biological Psychiatry , vol.61 , Issue.10 , pp. 1204-1207
    • Braff, D.L.1    Light, G.A.2    Swerdlow, N.R.3
  • 48
    • 33748067772 scopus 로고    scopus 로고
    • Prepulse inhibition and P50 suppression: Commonalities and dissociations
    • DOI 10.1016/j.psychres.2005.11.002, PII S0165178105003665
    • Oranje B, Geyer MA, Bocker KB, Leon Kenemans J, Verbaten MN (2006) Prepulse inhibition and P50 suppression: Commonalities and dissociations. Psychiatry Res 143:147-158. (Pubitemid 44301523)
    • (2006) Psychiatry Research , vol.143 , Issue.2-3 , pp. 147-158
    • Oranje, B.1    Geyer, M.A.2    Bocker, K.B.E.3    Leon, K.J.4    Verbaten, M.N.5
  • 49
    • 0027254757 scopus 로고
    • Concurrent assessment of acoustic startle and auditory P50 evoked potential measures of sensory inhibition
    • Schwarzkopf SB, Lamberti JS, Smith DA (1993) Concurrent assessment of acoustic startle and auditory P50 evoked potential measures of sensory inhibition. Biol Psychiatry 33:815-828. (Pubitemid 23234633)
    • (1993) Biological Psychiatry , vol.33 , Issue.11-12 , pp. 815-828
    • Schwarzkopf, S.B.1    Lamberti, J.S.2    Smith, D.A.3
  • 50
    • 36849047394 scopus 로고    scopus 로고
    • Evidence of Missense Mutations on the Neuregulin 1 Gene Affecting Function of Prepulse Inhibition
    • DOI 10.1016/j.biopsych.2007.05.011, PII S0006322307004775, Schizophrenia: From Genetics to Treatment
    • Hong LE, Wonodi I, Stine OC, Mitchell BD, Thaker GK (2008) Evidence of missense mutations on the neuregulin 1 gene affecting function of prepulse inhibition. Biol Psychiatry 63:17-23. (Pubitemid 350234892)
    • (2008) Biological Psychiatry , vol.63 , Issue.1 , pp. 17-23
    • Hong, L.E.1    Wonodi, I.2    Stine, O.C.3    Mitchell, B.D.4    Thaker, G.K.5
  • 51
    • 79951646083 scopus 로고    scopus 로고
    • The influence of schizophreniarelated neuregulin-1 polymorphisms on sensorimotor gating in healthy males
    • Roussos P, Giakoumaki SG, Adamaki E, Bitsios P (2011) The influence of schizophreniarelated neuregulin-1 polymorphisms on sensorimotor gating in healthy males. Biol Psychiatry 69:479-486.
    • (2011) Biol Psychiatry , vol.69 , pp. 479-486
    • Roussos, P.1    Giakoumaki, S.G.2    Adamaki, E.3    Bitsios, P.4
  • 52
    • 33748924655 scopus 로고    scopus 로고
    • Intermediate phenotypes and genetic mechanisms of psychiatric disorders
    • DOI 10.1038/nrn1993, PII NRN1993
    • Meyer-Lindenberg A, Weinberger DR (2006) Intermediate phenotypes and genetic mechanisms of psychiatric disorders. Nat Rev Neurosci 7:818-827. (Pubitemid 44435264)
    • (2006) Nature Reviews Neuroscience , vol.7 , Issue.10 , pp. 818-827
    • Meyer-Lindenberg, A.1    Weinberger, D.R.2
  • 53
    • 79959843898 scopus 로고    scopus 로고
    • P50 sensory gating and smoking in the general population
    • Brinkmeyer J, et al. (2011) P50 sensory gating and smoking in the general population. Addict Biol 16:485-498.
    • (2011) Addict Biol , vol.16 , pp. 485-498
    • Brinkmeyer, J.1
  • 54
    • 0031786335 scopus 로고    scopus 로고
    • Nicotine dependence in schizophrenia: Clinical phenomena and laboratory findings
    • Dalack GW, Healy DJ, Meador-Woodruff JH (1998) Nicotine dependence in schizophrenia: Clinical phenomena and laboratory findings. Am J Psychiatry 155:1490-1501. (Pubitemid 28512015)
    • (1998) American Journal of Psychiatry , vol.155 , Issue.11 , pp. 1490-1501
    • Dalack, G.W.1    Healy, D.J.2    Meador-Woodruff, J.H.3
  • 56
    • 0033967022 scopus 로고    scopus 로고
    • Differential expression patterns of the basic Helix-Loop-Helix transcription factors during aging of the murine brain
    • DOI 10.1016/S0304-3940(00)00761-8, PII S0304394000007618
    • Uittenbogaard M, Chiaramello A (2000) Differential expression patterns of the basic helix-loop-helix transcription factors during aging of the murine brain. Neurosci Lett 280:95-98. (Pubitemid 30109141)
    • (2000) Neuroscience Letters , vol.280 , Issue.2 , pp. 95-98
    • Uittenbogaard, M.1    Chiaramello, A.2
  • 57
    • 0029896451 scopus 로고    scopus 로고
    • B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB
    • Zhuang Y, Cheng P, Weintraub H (1996) B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB. Mol Cell Biol 16:2898-2905. (Pubitemid 26161295)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.6 , pp. 2898-2905
    • Zhuang, Y.1    Cheng, P.2    Weintraub, H.3
  • 58
    • 67651022598 scopus 로고    scopus 로고
    • Quantifying and correcting for the winner's curse in genetic association studies
    • Xiao R, Boehnke M (2009) Quantifying and correcting for the winner's curse in genetic association studies. Genet Epidemiol 33:453-462.
    • (2009) Genet Epidemiol , vol.33 , pp. 453-462
    • Xiao, R.1    Boehnke, M.2
  • 59
    • 32344443686 scopus 로고    scopus 로고
    • Attenuation of the prepulse inhibition of the acoustic startle response within and between sessions
    • DOI 10.1016/j.biopsycho.2005.05.001, PII S0301051105000864
    • Quednow BB, et al. (2006) Attenuation of the prepulse inhibition of the acoustic startle response within and between sessions. Biol Psychol 71:256-263. (Pubitemid 43220622)
    • (2006) Biological Psychology , vol.71 , Issue.3 , pp. 256-263
    • Quednow, B.B.1    Kuhn, K.-U.2    Beckmann, K.3    Westheide, J.4    Maier, W.5    Wagner, M.6
  • 61
    • 51349156208 scopus 로고    scopus 로고
    • Variants in nicotinic receptors and risk for nicotine dependence
    • Bierut LJ, et al. (2008) Variants in nicotinic receptors and risk for nicotine dependence. Am J Psychiatry 165:1163-1171.
    • (2008) Am J Psychiatry , vol.165 , pp. 1163-1171
    • Bierut, L.J.1
  • 63
    • 77951751034 scopus 로고    scopus 로고
    • Meta-analysis and imputation refines the association of 15q25 with smoking quantity
    • Wellcome Trust Case Control Consortium
    • Liu JZ, et al.; Wellcome Trust Case Control Consortium (2010) Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet 42:436-440.
    • (2010) Nat Genet , vol.42 , pp. 436-440
    • Liu, J.Z.1
  • 64
    • 77952420982 scopus 로고    scopus 로고
    • Sensorimotor gating is associated with CHRNA3 polymorphisms in schizophrenia and healthy volunteers
    • Petrovsky N, et al. (2010) Sensorimotor gating is associated with CHRNA3 polymorphisms in schizophrenia and healthy volunteers. Neuropsychopharmacology 35: 1429-1439.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1429-1439
    • Petrovsky, N.1
  • 65
    • 78851471766 scopus 로고    scopus 로고
    • Risk gene variants for nicotine dependence in the CHRNA5-CHRNA3-CHRNB4 cluster are associated with cognitive performance
    • Winterer G, et al. (2010) Risk gene variants for nicotine dependence in the CHRNA5-CHRNA3-CHRNB4 cluster are associated with cognitive performance. Am J Med Genet B Neuropsychiatr Genet 153B:1448-1458.
    • (2010) Am J Med Genet B Neuropsychiatr Genet , vol.153 B , pp. 1448-1458
    • Winterer, G.1
  • 66
    • 33644614050 scopus 로고    scopus 로고
    • Why do young women smoke? I. Direct and interactive effects of environment, psychological characteristics and nicotinic cholinergic receptor genes
    • Greenbaum L, et al. (2006) Why do young women smoke? I. Direct and interactive effects of environment, psychological characteristics and nicotinic cholinergic receptor genes. Mol Psychiatry 11:312-322.
    • (2006) Mol Psychiatry , vol.11 , pp. 312-322
    • Greenbaum, L.1
  • 67
    • 78649627035 scopus 로고    scopus 로고
    • Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans
    • Saccone NL, et al. (2010) Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans. Genes Brain Behav 9:741-750.
    • (2010) Genes Brain Behav , vol.9 , pp. 741-750
    • Saccone, N.L.1
  • 68
    • 45149108420 scopus 로고    scopus 로고
    • Mapping the genetic architecture of gene expression in human liver
    • Schadt EE, et al. (2008) Mapping the genetic architecture of gene expression in human liver. PLoS Biol 6:e107.
    • (2008) PLoS Biol , vol.6
    • Schadt, E.E.1
  • 69
    • 0033815626 scopus 로고    scopus 로고
    • Nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in CA1 interneurons of rat hippocampus
    • Alkondon M, Pereira EF, Almeida LE, Randall WR, Albuquerque EX (2000) Nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in CA1 interneurons of rat hippocampus. Neuropharmacology 39: 2726-2739.
    • (2000) Neuropharmacology , vol.39 , pp. 2726-2739
    • Alkondon, M.1    Pereira, E.F.2    Almeida, L.E.3    Randall, W.R.4    Albuquerque, E.X.5
  • 71
    • 0033832470 scopus 로고    scopus 로고
    • Abnormal regulation of high affinity nicotinic receptors in subjects with schizophrenia
    • Breese CR, et al. (2000) Abnormal regulation of high affinity nicotinic receptors in subjects with schizophrenia. Neuropsychopharmacology 23:351-364.
    • (2000) Neuropsychopharmacology , vol.23 , pp. 351-364
    • Breese, C.R.1
  • 72
    • 0035726679 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptor subunit knockout mice: Physiological and behavioral phenotypes and possible clinical implications
    • DOI 10.1016/S0163-7258(01)00161-9, PII S0163725801001619
    • Picciotto MR, et al. (2001) Neuronal nicotinic acetylcholine receptor subunit knockout mice: Physiological and behavioral phenotypes and possible clinical implications. Pharmacol Ther 92:89-108. (Pubitemid 34251128)
    • (2001) Pharmacology and Therapeutics , vol.92 , Issue.2-3 , pp. 89-108
    • Picciotto, M.R.1    Caldarone, B.J.2    Brunzell, D.H.3    Zachariou, V.4    Stevens, T.R.5    King, S.L.6
  • 73
    • 31044439244 scopus 로고    scopus 로고
    • Indirect modulation by α7 nicotinic acetylcholine receptors of noradrenaline release in rat hippocampal slices: Interaction with glutamate and GABA systems and effect of nicotine withdrawal
    • DOI 10.1124/mol.105.018184
    • Barik J, Wonnacott S (2006) Indirect modulation by alpha7 nicotinic acetylcholine receptors of noradrenaline release in rat hippocampal slices: Interaction with glutamate and GABA systems and effect of nicotine withdrawal. Mol Pharmacol 69:618-628. (Pubitemid 43121959)
    • (2006) Molecular Pharmacology , vol.69 , Issue.2 , pp. 618-628
    • Barik, J.1    Wonnacott, S.2
  • 74
    • 55849115277 scopus 로고    scopus 로고
    • Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons
    • Satta R, et al. (2008) Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons. Proc Natl Acad Sci USA 105:16356-16361.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16356-16361
    • Satta, R.1
  • 75
    • 77349102500 scopus 로고    scopus 로고
    • The effect of smoking on MAOA promoter methylation in DNA prepared from lymphoblasts and whole blood
    • Philibert RA, et al. (2010) The effect of smoking on MAOA promoter methylation in DNA prepared from lymphoblasts and whole blood. Am J Med Genet B Neuropsychiatr Genet 153:619-628.
    • (2010) Am J Med Genet B Neuropsychiatr Genet , vol.153 , pp. 619-628
    • Philibert, R.A.1
  • 76
    • 49649084390 scopus 로고    scopus 로고
    • Correlation between genetic and geographic structure in Europe
    • Lao O, et al. (2008) Correlation between genetic and geographic structure in Europe. Curr Biol 18:1241-1248.
    • (2008) Curr Biol , vol.18 , pp. 1241-1248
    • Lao, O.1
  • 77
    • 84860570267 scopus 로고    scopus 로고
    • Linking substance use with symptoms of sub-clinical psychosis in a community cohort over 30 years
    • in press
    • Rossler W, Hengartner MP, Angst J, Ajdacic-Gross V (2012) Linking substance use with symptoms of sub-clinical psychosis in a community cohort over 30 years. Addiction, in press.
    • (2012) Addiction
    • Rossler, W.1    Hengartner, M.P.2    Angst, J.3    Ajdacic-Gross, V.4
  • 79
    • 79959842438 scopus 로고    scopus 로고
    • The German multi-centre study on smoking-related behavior-description of a population-based case-control study
    • Lindenberg A, et al. (2011) The German multi-centre study on smoking-related behavior-description of a population-based case-control study. Addict Biol 16:638-653.
    • (2011) Addict Biol , vol.16 , pp. 638-653
    • Lindenberg, A.1
  • 81
    • 0032570640 scopus 로고    scopus 로고
    • Multiple site evaluation of P50 suppression among schizophrenia and normal comparison subjects
    • DOI 10.1016/S0920-9964(97)00122-9, PII S0920996497001229
    • Clementz BA, Geyer MA, Braff DL (1998) Multiple site evaluation of P50 suppression among schizophrenia and normal comparison subjects. Schizophr Res 30:71-80. (Pubitemid 28097252)
    • (1998) Schizophrenia Research , vol.30 , Issue.1 , pp. 71-80
    • Clementz, B.A.1    Geyer, M.A.2    Braff, D.L.3


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