Effects of propofol and pentobarbital on calcium concentration in presynaptic boutons on a rat hippocampal neuron

Journal of Anesthesia

Volumn 25, Issue 5, 2011, Pages 727-733

  Ito, Shinichi ^a   Sugiyama, Hitomi ^a   Kitahara, Seiko ^a   Ikemoto, Yoshimi ^b   Yokoyama, Takeshi ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b Hisatsune Hospital   (Japan)

Author keywords

Calcium signaling; Hippocampus; Pentobarbital; Presynaptic terminals; Propofol

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ANESTHETIC AGENT; BENZODIAZEPINE RECEPTOR AFFECTING AGENT; CALCIUM; PENTOBARBITAL; POTASSIUM; PROPOFOL;

ANIMAL; ARTICLE; DRUG EFFECT; HIPPOCAMPUS; METABOLISM; NERVE CELL; RAT; SPRAGUE DAWLEY RAT; SYNAPSE; SYNAPTIC TRANSMISSION; SYNAPTOSOME;

ANESTHETICS; ANIMALS; CALCIUM; GABA MODULATORS; HIPPOCAMPUS; NEURONS; NEUROTRANSMITTER AGENTS; PENTOBARBITAL; POTASSIUM; PRESYNAPTIC TERMINALS; PROPOFOL; RATS; RATS, SPRAGUE-DAWLEY; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 84859909701     PISSN: 09138668     EISSN: 14388359     Source Type: Journal    
DOI: 10.1007/s00540-011-1186-4     Document Type: Article

References (35)

1. A receptors suggest a similar mechanism of action. Can J Physiol Pharmacol. 1998;76:46-52.
2. Mantz J, Lecharny JB, Laudenbach V, Henzel D, Peytavin G, Desmonts JM. Anesthetics affect the uptake but not the depolarization-evoked release of GABA in rat striatal synaptosomes. Anesthesiology. 1995;82:502-11.
3. A receptor single-channel currents. Anesth Analg. 2004;99:409-15.
4. A receptors in cultured murine hippocampal neurons. J Neurosci. 1994;14:7747-60.
5. A channel conductance in rat-cultured hippocampal neurons. Eur J Pharmacol. 2003;468:75-82.
6. McDougall SJ, Bailey TW, Mendelowitz D, Andresen MC. Propofol enhances both tonic and phasic inhibitory currents in second-order neurons of the solitary tract nucleus (NTS). Neuropharmacology. 2008;54:552-63.
7. A receptors by pentobarbital occurs through a different mechanism than activation by GABA. Neurosci Lett. 2010;471:195-9.
8. Frenkel C, Urban BW. Human brain sodium channels as one of the molecular target sites for the new intravenous anaesthetic propofol (2, 6-diisopropylphenol). Eur J Pharmacol. 1991;208:75-9.
9. Jones PJ, Wang Y, Smith MD, Hargus NJ, Eidam HS, White HS, Kapur J, Brown ML, Patel MK. Hydroxyamide analogs of propofol exhibit state-dependent block of sodium channels in hippocampal neurons: implications for anticonvulsant activity. J Pharmacol Exp Ther. 2007;320:828-36. (Pubitemid 46147965)
10. Kozinn J, Mao L, Arora A, Yang L, Fibuch EE, Wang JQ. Inhibition of glutamatergic activation of extracellular signal-regulated protein kinases in hippocampal neurons by the intravenous anesthetic propofol. Anesthesiology. 2006;105:1182-91. (Pubitemid 44808582)
11. Wei H, Xiong W, Yang S, Zhou Q, Liang C, Zeng BX, Xu L. Propofol facilitates the development of long-term depression (LTD) and impairs the maintenance of long-term potentiation (LTP) in the CA1 region of the hippocampus of anesthetized rats. Neurosci Lett. 2002;324:181-4. (Pubitemid 34493864)
12. Zhang H, Wang W, Gao W, Ge Y, Zhang J, Wu S, Xu L. Effect of propofol on the levels of neurotransmitters in normal human brain: a magnetic resonance spectroscopy study. Neurosci Lett. 2009;467:247-51.
13. Buggy DJ, Nicol B, Rowbotham DJ, Lambert DG. Effects of intravenous anesthetic agents on glutamate release: a role for GABAA receptor-mediated inhibition. Anesthesiology. 2000;92:1067-73. (Pubitemid 30180984)
14. Jin YH, Zhang Z, Mendelowitz D, Andresen MC. Presynaptic actions of propofol enhance inhibitory synaptic transmission in isolated solitary tract nucleus neurons. Brain Res. 2009;1286:75-83.
15. Westphalen RI, Hemmings HC Jr. Selective depression by general anesthetics of glutamate versus GABA release from isolated cortical nerve terminals. J Pharmacol Exp Ther. 2003;304:1188-96. (Pubitemid 36254432)
16. A receptors. Naunyn Schmiedebergs Arch Pharmacol. 2002;366:246-53.
17. Baudoux S, Empson RM, Richards CD. Pentobarbitone modulates calcium transients in axons and synaptic boutons of hippocampal CA1 neurons. Br J Pharmacol. 2003;140:971-9. (Pubitemid 37464081)
18. Richards CD. Anaesthetic modulation of synaptic transmission in the mammalian CNS. Br J Anaesth. 2002;89:79-90. (Pubitemid 34778105)
19. Schneggenburger R, Nehr E. Presynaptic calcium and control of vesicle fusion. Curr Opin Neurobiol. 2005;15:266-74. (Pubitemid 40806437)
20. Llinás R, Sugimori M, Silver RB. Presynaptic calcium concentration microdomains and transmitter release. J Physiol Paris. 1992;86:135-8. (Pubitemid 23061484)
21. A response under experimental ischemia in acutely dissociated CA1 pyramidal neurones of the rat. J Physiol. 1997;500:673-88.
22. Akaike N, Murakami N, Katsurabayashi S, Jin YH, Imazawa T. Focal stimulation of single GABAergic presynaptic boutons on the rat hippocampal neuron. Neurosci Res. 2002;42:187-95. (Pubitemid 34230407)
23. 2+ concentration and histamine release in rat peritoneal mast cells. Br J Pharmacol. 2003;139:381-7.
24. Lemke EA, Klingauf J. Single synaptic vesicle tracking in individual hippocampal boutons at rest and during synaptic activity. J Neurosci. 2005;25:11034-44. (Pubitemid 41692633)
25. Darrin H, Brager DH, Luther PW, Erdélyi F, Szabó G, Alger BE. Regulation of exocytosis from single visualized GABAergic boutons in hippocampal slices. J Neurosci. 2003;23:10475-86. (Pubitemid 37485260)
26. Takahashi T, Momiyama A. Different types of calcium channels mediate central synaptic transmission. Nature. 1993;366:156-8. (Pubitemid 23351819)
27. 2+ channels with presynaptic SNARE proteins. Proc Natl Acad Sci USA. 1997;94:14782-6.
28. Robataille R, Adler EM, Charlton MP. Strategic location of calcium channels at transmitter release sites of frog neuromuscular synapses. Neuron. 1990;5:773-9.
29. Tibbs GR, Barrie AP, Van Mieghem FJE, McMahon HT, Nicholls DG. Repetitive action potentials in isolated nerve terminals in the presence of 4-aminopyridine: effects on cytosolic free Ca2+ and glutamate release. J Neurochem. 1989;53:1693-9. (Pubitemid 19283636)
30. Leuner B, Falduto J, Shors TJ. Associative memory formation increases the observation of dendritic spines in the hippocampus. J Neurosci. 2003;23:659-65. (Pubitemid 36139564)
31. Harris KM, Kater SB. Dendritic spines: cellular specializations imparting both stability and flexibility to synaptic function. Annu Rev Neurosci. 1994;17:341-71. (Pubitemid 24117034)
32. Eccles JC, Schmidt RF, Willis WD. Pharmacological studies of presynaptic inhibition. J Physiol. 1963;168:500-30.
33. Axmacher N, Winterer J, Stanton PK, Draguhn A, Müller W. Two-photon imaging of spontaneous vesicular release in acute brain slices and its modulation by presynaptic GABAA receptors. Neuro Image. 2004;22:1014-21. (Pubitemid 38759467)
34. Fischer Y, Parnas I. Differential activation of two distinct mechanisms for presynaptic inhibition by a single inhibitory axon. J Neurophysiol. 1996;76:3807-16. (Pubitemid 27009684)
35. A receptors affect the release machinery. J Neurophysiol. 2000;84:1240-6.