Pharmacological manipulation of the dopaminergic system affects wheel-running activity in differentially active mice

Journal of Biological Regulators and Homeostatic Agents

Volumn 26, Issue 1, 2012, Pages 119-129

  Knab, Amy M ^a   Bowen, R S ^b   Hamilton, A T ^c   Lightfoot, J T ^d  

^a APPALACHIAN STATE UNIVERSITY   (United States)

^b Science and Mathematics Division   (United States)

^c CAROLINAS MEDICAL CENTER   (United States)

^d TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Dopamine; Dopamine signaling; Genetics; Inbred mice; Physical activity; Regulation

Indexed keywords

1 [2 (BENZHYDRYLOXY)ETHYL] 4 (3 PHENYLALLYL)PIPERAZINE; 6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; DL 2 METHYL 3 (4 HYDROXYPHENYL)ALANINE; DOPAMINE; HYDROLASE INHIBITOR; PLACEBO; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DOPAMINE UPTAKE; DOPAMINERGIC SYSTEM; DOSE RESPONSE; DRUG EFFECT; FEMALE; GENETIC REGULATION; GENETIC VARIABILITY; INBRED STRAIN; MALE; MOUSE; NONHUMAN; PHYSICAL ACTIVITY; SIGNAL TRANSDUCTION; TREADMILL; VELOCITY;

ANIMALS; BENZAZEPINES; BODY WEIGHT; DOPAMINE AGONISTS; ENZYME INHIBITORS; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MOTOR ACTIVITY; PIPERAZINES; RECEPTORS, DOPAMINE D1; TIME FACTORS; TYROSINE 3-MONOOXYGENASE;

MUS;

EID: 84859907544     PISSN: 0393974X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Heitmann BL, Hills AP, Frederiksen P, Ward LC. Obesity, leanness, and mortality: effect modification by physical activity in men and women. Obesity (Silver Spring) 2009; 17(1):136-42. (Pubitemid 50324550)
2. Oldridge NB. Economic burden of physical inactivity: healthcare costs associated with cardiovascular disease. Eur J Cardiovasc Prev Rehabil 2008; 15(2):130-9. (Pubitemid 351507642)
3. Festing MF. Wheel activity in 26 strains of mouse. Lab Anim 1977; 11(4):257-8. (Pubitemid 8193047)
4. Lauderdale DS, Fabsitz R, Meyer JM, Sholinsky P, Ramakrishnan V, Goldberg J. Familial determinants of moderate and intense physical activity: a twin study. Med Sci Sports Exerc 1997; 29(8):1062-8. (Pubitemid 27349773)
5. Lerman I, Harrison BC, Freeman K, et al. Genetic variability in forced and voluntary endurance exercise performance in seven inbred mouse strains. J Applied Physiol 2002; 92(6):2245-55. (Pubitemid 34666344)
6. Lightfoot JT, Turner MJ, Daves M, Vordermark A, Kleeberger SR. Genetic influence on daily wheel running activity level. Physiol Genomics 2004; 19(3):270-6.
7. Stubbe JH, Boomsma DI, De Geus EJ. Sports participation during adolescence: a shift from environmental to genetic factors. Med Sci Sports Exerc 2005; 37(4):563-70. (Pubitemid 40478460)
8. Lightfoot JT, Turner MJ, Pomp D, Kleeberger SR, Leamy LJ. Quantitative trait loci (QTL) for physical activity traits in mice. Physiol Genomics 2008; 32(3):401-8. (Pubitemid 351328563)
9. Leamy LJ, Pomp D, Lightfoot JT. An epistatic genetic basis for physical activity traits in mice. J Hered 2008; 99(6):639-46.
10. Rezende EL, Kelly SA, Gomes FR, Chappell MA, Garland T, Jr. Effects of size, sex, and voluntary running speeds on costs of locomotion in lines of laboratory mice selectively bred for high wheel-running activity. Physiol Biochem Zool 2006; 79(1):83-99. (Pubitemid 43112607)
11. Bronikowski AM, Rhodes JS, Garland T, Jr, Prolla TA, Awad TA, Gammie SC. The evolution of gene expression in mouse hippocampus in response to selective breeding for increased locomotor activity. Evolution Int J Org Evolution 2004; 58(9):2079-86. (Pubitemid 39348507)
12. Rhodes JS, Garland T. Differential sensitivity to acute administration of Ritalin, apomorphine, SCH 23390, but not raclopride in mice selectively bred for hyperactive wheel-running behavior. Psychopharmacology (Berl) 2003; 167(3):242-50. (Pubitemid 36712970)
13. Rhodes JS, Garland T, Jr, Gammie SC. Patterns of brain activity associated with variation in voluntary wheel-running behavior. Behav Neurosci 2003; 117(6):1243-56. (Pubitemid 37549426)
14. Rhodes JS, Hosack GR, Girard I, Kelley AE, Mitchell GS, Garland T, Jr. Differential sensitivity to acute administration of cocaine, GBR 12909, and fluoxetine in mice selectively bred for hyperactive wheel-running behavior. Psychopharmacology (Berl) 2001; 158(2):120-31. (Pubitemid 33020830)
15. Salamone JD. Complex motor and sensorimotor functions of striatal and accumbens dopamine: involvement in instrumental behavior processes. Psychopharmacology (Berl) 1992; 107(2-3):160-74.
16. Salamone JD, Correa M. Motivational views of reinforcement: implications for understanding the behavioral functions of nucleus accumbens dopamine. Behav Brain Res 2002; 137(1-2):3-25. (Pubitemid 35346426)
17. Zhang J, Goodlett DR. Proteomic approach to studying Parkinson's disease. Mol Neurobiol 2004; 29(3):271-88. (Pubitemid 41359111)
18. Arnsten AF. Fundamentals of attention-deficit/hyperactivity disorder: circuits and pathways. J Clin Psychiatry 2006; 67(S):7-12.
19. Gold LH, Swerdlow NR, Koob GF. The role of mesolimbic dopamine in conditioned locomotion produced by amphetamine. Behav Neurosci 1988; 102(4):544-52.
20. Saylor AJ, McGinty JF. Amphetamine-induced locomotion and gene expression are altered in BDNF heterozygous mice. Genes Brain Behav 2008.
21. Knab AM, Bowen RS, Hamilton AT, Gulledge AA, Lightfoot JT. Altered dopaminergic profiles: implications for the regulation of voluntary physical activity. Behav Brain Res 2009; 204(1):147-52.
22. Eikelboom R. Human parallel to voluntary wheel running: exercise. Anim Behav 1999; 57(3):F11-F12. (Pubitemid 129746999)
23. Sherwin CM. Voluntary wheel running: a review and novel interpretation. Anim Behav 1998; 56(1):11-27. (Pubitemid 28348956)
24. Swallow JG, Garland T, Jr, Carter PA, Zhan WZ, Sieck GC. Effects of voluntary activity and genetic selection on aerobic capacity in house mice (Mus domesticus). J Appl Physiol 1998; 84(1):69-76. (Pubitemid 28065112)
25. Knab AM, Bowen RS, Moore-Harrison T, Hamilton AT, Turner MJ, Lightfoot JT. Repeatability of exercise behaviors in mice Physiol Behav 2009.
26. Leamy LJ, Pomp D, Lightfoot JT. A search for quantitative trait loci controlling within-individual variation of physical activity traits in mice. BMC Genet 2010; 11:83.
27. Lightfoot JT. Current understanding of the genetic basis for physical activity J Nutr 2011; 141(3):526-30.
28. Lightfoot JT, Leamy L, Pomp D, et al. Strain screen and haplotype association mapping of wheel running in inbred mouse strains. J Appl Physiol 2010; 109(3):623-34.
29. Rankinen T, Bray MS, Hagberg JM, et al. The human gene map for performance and health-related fitness phenotypes: the 2005 update. Med Sci Sports Exerc 2006; 38(11):1863-88. (Pubitemid 44707790)
30. Garland T, Jr, Schutz H, Chappell MA, et al. The biological control of voluntary exercise, spontaneous physical activity and daily energy expenditure in relation to obesity: human and rodent perspectives. J Exp Biol 2011; 214(Pt 2):206-29.
31. Greenwald MK, Schuster CR, Johanson CE, Jewell J. Automated measurement of motor activity in human subjects: effects of repeated testing and d-amphetamine. Pharmacol Biochem Behav 1998; 59(1):59-65. (Pubitemid 28053680)
32. Robbins TW, Sahakian BJ. "Paradoxical" effects of psychomotor stimulant drugs in hyperactive children from the standpoint of behavioural pharmacology. Neuropharmacology 1979; 18(12):931-50. (Pubitemid 10117383)
33. Sanger DJ, Blackman DE. Rate-dependent effects of drugs: a review of the literature. Pharmacol Biochem Behav 1976; 4(1):73-83.