메뉴 건너뛰기




Volumn 27, Issue 5, 2012, Pages 1186-1195

Use of selective serotonin reuptake inhibitors and risk of fracture: A systematic review and meta-analysis

Author keywords

ANTIDEPRESSANTS; FRACTURE; META ANALYSIS; SELECTIVE SEROTONIN REUPTAKE INHIBITOR

Indexed keywords

SEROTONIN UPTAKE INHIBITOR;

EID: 84859906973     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1554     Document Type: Review
Times cited : (106)

References (53)
  • 1
    • 79957583113 scopus 로고    scopus 로고
    • Use of acid-suppressive drugs and risk of fracture: A meta-analysis of observational studies
    • Eom CS, Park SM, Myung SK, et al. Use of acid-suppressive drugs and risk of fracture: a meta-analysis of observational studies. Ann Fam Med. 2011; 9: 257-67.
    • (2011) Ann Fam Med. , vol.9 , pp. 257-267
    • Eom, C.S.1    Park, S.M.2    Myung, S.K.3
  • 2
    • 79951983392 scopus 로고    scopus 로고
    • Use of acid-suppressive drugs and risk of pneumonia: A systematic review and meta-analysis
    • Eom CS, Jeon CY, Lim JW, et al. Use of acid-suppressive drugs and risk of pneumonia: a systematic review and meta-analysis. CMAJ. 2011; 183: 310-9.
    • (2011) CMAJ , vol.183 , pp. 310-319
    • Eom, C.S.1    Jeon, C.Y.2    Lim, J.W.3
  • 3
    • 69249206626 scopus 로고    scopus 로고
    • SSRIs, bone mineral density, and risk of fractures-a review
    • Schwan S, Hallberg P., SSRIs, bone mineral density, and risk of fractures-a review. Eur Neuropsychopharmacol. 2009; 19: 683-92.
    • (2009) Eur Neuropsychopharmacol. , vol.19 , pp. 683-692
    • Schwan, S.1    Hallberg, P.2
  • 4
    • 34347220867 scopus 로고    scopus 로고
    • Use of antidepressants and rates of hip bone loss in older women: The study of osteoporotic fractures
    • Diem SJ, Blackwell TL, Stone KL, et al. Use of antidepressants and rates of hip bone loss in older women: the study of osteoporotic fractures. Arch Intern Med. 2007; 167: 1240-5.
    • (2007) Arch Intern Med. , vol.167 , pp. 1240-1245
    • Diem, S.J.1    Blackwell, T.L.2    Stone, K.L.3
  • 5
    • 33845970601 scopus 로고    scopus 로고
    • Osteoporosis and its management
    • Poole KE, Compston JE., Osteoporosis and its management. BMJ. 2006; 333: 1251-6.
    • (2006) BMJ , vol.333 , pp. 1251-1256
    • Poole, K.E.1    Compston, J.E.2
  • 6
    • 0037129560 scopus 로고    scopus 로고
    • Epidemiology and outcomes of osteoporotic fractures
    • Cummings SR, Melton LJ., Epidemiology and outcomes of osteoporotic fractures. Lancet. 2002; 359: 1761-7.
    • (2002) Lancet , vol.359 , pp. 1761-1767
    • Cummings, S.R.1    Melton, L.J.2
  • 7
    • 11844251380 scopus 로고    scopus 로고
    • Office of the Surgeon General Rockville, MD: US Department of Health and Human Services Oct 14 [accessed 2011 Oct]
    • Office of the Surgeon General. Bone health and osteoporosis: a report of the Surgeon General [Internet]. Rockville, MD: US Department of Health and Human Services; 2004 Oct 14 [accessed 2011 Oct]. Available from:.
    • (2004) Bone Health and Osteoporosis: A Report of the Surgeon General [Internet]
  • 8
    • 34247194211 scopus 로고    scopus 로고
    • Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025
    • Burge R, Dawson-Hughes B, Solomon DH, et al. Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025. J Bone Miner Res. 2007; 22: 465-75.
    • (2007) J Bone Miner Res. , vol.22 , pp. 465-475
    • Burge, R.1    Dawson-Hughes, B.2    Solomon, D.H.3
  • 9
    • 32644438120 scopus 로고    scopus 로고
    • Prevalence and predictors of depression in elderly Canadians: The Canadian Study of Health and Aging
    • Ostbye T, Kristjansson B, Hill G, et al. Prevalence and predictors of depression in elderly Canadians: the Canadian Study of Health and Aging. Chronic Dis Can. 2005; 26: 93-9.
    • (2005) Chronic Dis Can. , vol.26 , pp. 93-99
    • Ostbye, T.1    Kristjansson, B.2    Hill, G.3
  • 10
    • 0030766770 scopus 로고    scopus 로고
    • Diagnosis and treatment of depression in late life. Consensus statement update
    • Lebowitz BD, Pearson JL, Schneider LS, et al. Diagnosis and treatment of depression in late life. Consensus statement update. JAMA. 1997; 278: 1186-90.
    • (1997) JAMA , vol.278 , pp. 1186-1190
    • Lebowitz, B.D.1    Pearson, J.L.2    Schneider, L.S.3
  • 11
    • 0033135307 scopus 로고    scopus 로고
    • Fortnightly review: Drug treatment of depression
    • Spigset O, Martensson B., Fortnightly review: drug treatment of depression. BMJ. 1999; 318: 1188-91.
    • (1999) BMJ , vol.318 , pp. 1188-1191
    • Spigset, O.1    Martensson, B.2
  • 12
    • 33846492331 scopus 로고    scopus 로고
    • Predictors of non-spine fracture in elderly men: The MrOS study
    • Lewis CE, Ewing SK, Taylor BC, et al. Predictors of non-spine fracture in elderly men: the MrOS study. J Bone Miner Res. 2007; 22: 211-9.
    • (2007) J Bone Miner Res. , vol.22 , pp. 211-219
    • Lewis, C.E.1    Ewing, S.K.2    Taylor, B.C.3
  • 13
    • 77955843946 scopus 로고    scopus 로고
    • Use of antidepressant drugs and risk of osteoporotic and non-osteoporotic fractures
    • Verdel BM, Souverein PC, Egberts TC, et al. Use of antidepressant drugs and risk of osteoporotic and non-osteoporotic fractures. Bone. 2010; 47: 604-9.
    • (2010) Bone. , vol.47 , pp. 604-609
    • Verdel, B.M.1    Souverein, P.C.2    Egberts, T.C.3
  • 14
    • 69949134927 scopus 로고    scopus 로고
    • Use of anti-depressants and the risk of fracture of the hip or femur
    • van den Brand MW, Pouwels S, Samson MM, et al. Use of anti-depressants and the risk of fracture of the hip or femur. Osteoporos Int. 2009; 20: 1705-13.
    • (2009) Osteoporos Int. , vol.20 , pp. 1705-1713
    • Van Den Brand, M.W.1    Pouwels, S.2    Samson, M.M.3
  • 15
    • 62149091078 scopus 로고    scopus 로고
    • Mapping the prescriptiome to fractures in men-a national analysis of prescription history and fracture risk
    • Abrahamsen B, Brixen K., Mapping the prescriptiome to fractures in men-a national analysis of prescription history and fracture risk. Osteoporos Int. 2009; 20: 585-97.
    • (2009) Osteoporos Int. , vol.20 , pp. 585-597
    • Abrahamsen, B.1    Brixen, K.2
  • 16
    • 54449099520 scopus 로고    scopus 로고
    • Fracture risk from psychotropic medications: A population-based analysis
    • Bolton JM, Metge C, Lix L, et al. Fracture risk from psychotropic medications: a population-based analysis. J Clin Psychopharmacol. 2008; 28: 384-91.
    • (2008) J Clin Psychopharmacol. , vol.28 , pp. 384-391
    • Bolton, J.M.1    Metge, C.2    Lix, L.3
  • 17
    • 54449089554 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibiting antidepressants are associated with an increased risk of nonvertebral fractures
    • Ziere G, Dieleman JP, van der Cammen TJ, et al. Selective serotonin reuptake inhibiting antidepressants are associated with an increased risk of nonvertebral fractures. J Clin Psychopharmacol. 2008; 28: 411-7.
    • (2008) J Clin Psychopharmacol. , vol.28 , pp. 411-417
    • Ziere, G.1    Dieleman, J.P.2    Van Der Cammen, T.J.3
  • 18
    • 42449154971 scopus 로고    scopus 로고
    • Depressive symptoms, bone loss, and fractures in postmenopausal women
    • Spangler L, Scholes D, Brunner RL, et al. Depressive symptoms, bone loss, and fractures in postmenopausal women. J Gen Intern Med. 2008; 23: 567-74.
    • (2008) J Gen Intern Med. , vol.23 , pp. 567-574
    • Spangler, L.1    Scholes, D.2    Brunner, R.L.3
  • 20
    • 33846440508 scopus 로고    scopus 로고
    • Effect of selective serotonin reuptake inhibitors on the risk of fracture
    • Richards JB, Papaioannou A, Adachi JD, et al. Effect of selective serotonin reuptake inhibitors on the risk of fracture. Arch Intern Med. 2007; 167: 188-94.
    • (2007) Arch Intern Med. , vol.167 , pp. 188-194
    • Richards, J.B.1    Papaioannou, A.2    Adachi, J.D.3
  • 21
    • 33646871582 scopus 로고    scopus 로고
    • Anxiolytics, sedatives, antidepressants, neuroleptics and the risk of fracture
    • Vestergaard P, Rejnmark L, Mosekilde L., Anxiolytics, sedatives, antidepressants, neuroleptics and the risk of fracture. Osteoporos Int. 2006; 17: 807-16.
    • (2006) Osteoporos Int. , vol.17 , pp. 807-816
    • Vestergaard, P.1    Rejnmark, L.2    Mosekilde, L.3
  • 22
    • 0038205572 scopus 로고    scopus 로고
    • Exposure to tricyclic and selective serotonin reuptake inhibitor antidepressants and the risk of hip fracture
    • Hubbard R, Farrington P, Smith C, et al. Exposure to tricyclic and selective serotonin reuptake inhibitor antidepressants and the risk of hip fracture. Am J Epidemiol. 2003; 158: 77-84.
    • (2003) Am J Epidemiol. , vol.158 , pp. 77-84
    • Hubbard, R.1    Farrington, P.2    Smith, C.3
  • 23
    • 0032474241 scopus 로고    scopus 로고
    • Use of selective serotonin-reuptake inhibitors or tricyclic antidepressants and risk of hip fractures in elderly people
    • Liu B, Anderson G, Mittmann N, et al. Use of selective serotonin-reuptake inhibitors or tricyclic antidepressants and risk of hip fractures in elderly people. Lancet. 1998; 351: 1303-7.
    • (1998) Lancet , vol.351 , pp. 1303-1307
    • Liu, B.1    Anderson, G.2    Mittmann, N.3
  • 24
    • 0032563909 scopus 로고    scopus 로고
    • Antidepressants and the risk of falls among nursing home residents
    • Thapa PB, Gideon P, Cost TW, et al. Antidepressants and the risk of falls among nursing home residents. N Engl J Med. 1998; 339: 875-82.
    • (1998) N Engl J Med. , vol.339 , pp. 875-882
    • Thapa, P.B.1    Gideon, P.2    Cost, T.W.3
  • 25
    • 0035012351 scopus 로고    scopus 로고
    • Retrospective review of selective serotonin reuptake inhibitors and falling in older nursing home residents
    • Arfken CL, Wilson JG, Aronson SM., Retrospective review of selective serotonin reuptake inhibitors and falling in older nursing home residents. Int Psychogeriatr. 2001; 13: 85-91.
    • (2001) Int Psychogeriatr. , vol.13 , pp. 85-91
    • Arfken, C.L.1    Wilson, J.G.2    Aronson, S.M.3
  • 26
    • 25844483751 scopus 로고    scopus 로고
    • Neural regulation of bone and the skeletal effects of serotonin (5-hydroxytryptamine)
    • Warden SJ, Bliziotes MM, Wiren KM, et al. Neural regulation of bone and the skeletal effects of serotonin (5-hydroxytryptamine). Mol Cell Endocrinol. 2005; 242: 1-9.
    • (2005) Mol Cell Endocrinol. , vol.242 , pp. 1-9
    • Warden, S.J.1    Bliziotes, M.M.2    Wiren, K.M.3
  • 29
    • 84859904215 scopus 로고    scopus 로고
    • Sheffield, UK: WHO Collaborating Center for Metabolic Bone Diseases; [accessed 2011 Nov]
    • WHO Fracture Risk Assessment Tool (FRAX) [Internet]. Sheffield, UK: WHO Collaborating Center for Metabolic Bone Diseases; [accessed 2011 Nov]. Available from:.
    • WHO Fracture Risk Assessment Tool (FRAX) [Internet]
  • 30
    • 77956402629 scopus 로고    scopus 로고
    • Depression, fracture risk, and bone loss: A meta-analysis of cohort studies
    • Wu Q, Liu J, Gallegos-Orozco JF, et al. Depression, fracture risk, and bone loss: a meta-analysis of cohort studies. Osteoporos Int. 2010; 21: 1627-35.
    • (2010) Osteoporos Int. , vol.21 , pp. 1627-1635
    • Wu, Q.1    Liu, J.2    Gallegos-Orozco, J.F.3
  • 31
    • 14844333195 scopus 로고    scopus 로고
    • Depression and hip fracture risk: The NHANES i epidemiologic follow-up study
    • Mussolino ME., Depression and hip fracture risk: The NHANES I epidemiologic follow-up study. Public Health Rep. 2005; 120: 71-5.
    • (2005) Public Health Rep. , vol.120 , pp. 71-75
    • Mussolino, M.E.1
  • 32
    • 0041876133 scopus 로고    scopus 로고
    • Measuring inconsistency in meta-analyses
    • Higgins JP, Thompson SG, Deeks JJ, et al. Measuring inconsistency in meta-analyses. BMJ. 2003; 327: 557-60.
    • (2003) BMJ , vol.327 , pp. 557-560
    • Higgins, J.P.1    Thompson, S.G.2    Deeks, J.J.3
  • 34
    • 0037471548 scopus 로고    scopus 로고
    • Central nervous system active medications and risk for fractures in older women
    • Ensrud KE, Blackwell T, Mangione CM, et al. Central nervous system active medications and risk for fractures in older women. Arch Intern Med. 2003; 163: 949-57.
    • (2003) Arch Intern Med. , vol.163 , pp. 949-957
    • Ensrud, K.E.1    Blackwell, T.2    Mangione, C.M.3
  • 35
    • 0035163962 scopus 로고    scopus 로고
    • Selective serotonin-reuptake inhibitor antidepressants increase the risk of falls and hip fractures in elderly people by inhibiting cardiovascular ion channels
    • Pacher P, Ungvari Z., Selective serotonin-reuptake inhibitor antidepressants increase the risk of falls and hip fractures in elderly people by inhibiting cardiovascular ion channels. Med Hypotheses. 2001; 57: 469-71.
    • (2001) Med Hypotheses. , vol.57 , pp. 469-471
    • Pacher, P.1    Ungvari, Z.2
  • 36
    • 58549113985 scopus 로고    scopus 로고
    • Risk of fractures with selective serotonin-reuptake inhibitors or tricyclic antidepressants
    • Ginzburg R, Rosero E., Risk of fractures with selective serotonin-reuptake inhibitors or tricyclic antidepressants. Ann Pharmacother. 2009; 43: 98-103.
    • (2009) Ann Pharmacother. , vol.43 , pp. 98-103
    • Ginzburg, R.1    Rosero, E.2
  • 37
    • 0034901881 scopus 로고    scopus 로고
    • Serum levels and cardiovascular effects of tricyclic antidepressants and selective serotonin reuptake inhibitors in depressed patients
    • Rodriguez de la Torre B, Dreher J, Malevany I, et al. Serum levels and cardiovascular effects of tricyclic antidepressants and selective serotonin reuptake inhibitors in depressed patients. Ther Drug Monit. 2001; 23: 435-40.
    • (2001) Ther Drug Monit. , vol.23 , pp. 435-440
    • Rodriguez De La Torre, B.1    Dreher, J.2    Malevany, I.3
  • 38
    • 0036125341 scopus 로고    scopus 로고
    • The role of dopamine and serotonin in regulating bone mass and strength: Studies on dopamine and serotonin transporter null mice
    • Bliziotes M, Gunness M, Eshleman A, et al. The role of dopamine and serotonin in regulating bone mass and strength: studies on dopamine and serotonin transporter null mice. J Musculoskelet Neuronal Interact. 2002; 2: 291-5.
    • (2002) J Musculoskelet Neuronal Interact. , vol.2 , pp. 291-295
    • Bliziotes, M.1    Gunness, M.2    Eshleman, A.3
  • 40
    • 0034747779 scopus 로고    scopus 로고
    • Neurotransmitter action in osteoblasts: Expression of a functional system for serotonin receptor activation and reuptake
    • Bliziotes MM, Eshleman AJ, Zhang XW, et al. Neurotransmitter action in osteoblasts: expression of a functional system for serotonin receptor activation and reuptake. Bone. 2001; 29: 477-86.
    • (2001) Bone. , vol.29 , pp. 477-486
    • Bliziotes, M.M.1    Eshleman, A.J.2    Zhang, X.W.3
  • 41
    • 12344334748 scopus 로고    scopus 로고
    • Serotonin regulates osteoclast differentiation through its transporter
    • Battaglino R, Fu J, Spate U, et al. Serotonin regulates osteoclast differentiation through its transporter. J Bone Miner Res. 2004; 19: 1420-31.
    • (2004) J Bone Miner Res. , vol.19 , pp. 1420-1431
    • Battaglino, R.1    Fu, J.2    Spate, U.3
  • 42
    • 34249313144 scopus 로고    scopus 로고
    • Serotonin transporter and receptor expression in osteocytic MLO-Y4 cells
    • Bliziotes M, Eshleman A, Burt-Pichat B, et al. Serotonin transporter and receptor expression in osteocytic MLO-Y4 cells. Bone. 2006; 39: 1313-21.
    • (2006) Bone. , vol.39 , pp. 1313-1321
    • Bliziotes, M.1    Eshleman, A.2    Burt-Pichat, B.3
  • 43
    • 84857113769 scopus 로고    scopus 로고
    • The adverse skeletal effects of selective serotonin reuptake inhibitors
    • Feb 2. [Epub ahead of print]
    • Tsapakis EM, Gamie Z, Tran GT, et al. The adverse skeletal effects of selective serotonin reuptake inhibitors. Eur Psychiatry. 2011 Feb 2. [Epub ahead of print].
    • (2011) Eur Psychiatry.
    • Tsapakis, E.M.1    Gamie, Z.2    Tran, G.T.3
  • 44
    • 56349162283 scopus 로고    scopus 로고
    • Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum
    • Yadav VK, Ryu JH, Suda N, et al. Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell. 2008; 135: 825-37.
    • (2008) Cell. , vol.135 , pp. 825-837
    • Yadav, V.K.1    Ryu, J.H.2    Suda, N.3
  • 45
    • 33645995104 scopus 로고    scopus 로고
    • Serotonin and fluoxetine modulate bone cell function in vitro
    • Gustafsson BI, Thommesen L, Stunes AK, et al. Serotonin and fluoxetine modulate bone cell function in vitro. J Cell Biochem. 2006; 98: 139-51.
    • (2006) J Cell Biochem. , vol.98 , pp. 139-151
    • Gustafsson, B.I.1    Thommesen, L.2    Stunes, A.K.3
  • 46
    • 34347262073 scopus 로고    scopus 로고
    • Association of low bone mineral density with selective serotonin reuptake inhibitor use by older men
    • Haney EM, Chan BK, Diem SJ, et al. Association of low bone mineral density with selective serotonin reuptake inhibitor use by older men. Arch Intern Med. 2007; 167: 1246-51.
    • (2007) Arch Intern Med. , vol.167 , pp. 1246-1251
    • Haney, E.M.1    Chan, B.K.2    Diem, S.J.3
  • 47
    • 25844464108 scopus 로고    scopus 로고
    • Factors associated with the lumbar spine and proximal femur bone mineral density in older men
    • Cauley JA, Fullman RL, Stone KL, et al. Factors associated with the lumbar spine and proximal femur bone mineral density in older men. Osteoporos Int. 2005; 16: 1525-37.
    • (2005) Osteoporos Int. , vol.16 , pp. 1525-1537
    • Cauley, J.A.1    Fullman, R.L.2    Stone, K.L.3
  • 48
    • 39849100862 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitor use and bone mineral density in women with a history of depression
    • Williams LJ, Henry MJ, Berk M, et al. Selective serotonin reuptake inhibitor use and bone mineral density in women with a history of depression. Int Clin Psychopharmacol. 2008; 23: 84-7.
    • (2008) Int Clin Psychopharmacol. , vol.23 , pp. 84-87
    • Williams, L.J.1    Henry, M.J.2    Berk, M.3
  • 49
    • 33744992495 scopus 로고    scopus 로고
    • Osteoporosis
    • Sambrook P, Cooper C., Osteoporosis. Lancet. 2006; 367: 2010-8.
    • (2006) Lancet , vol.367 , pp. 2010-2018
    • Sambrook, P.1    Cooper, C.2
  • 50
    • 0027968619 scopus 로고
    • Evidence of the depletion of susceptibles effect in non-experimental pharmacoepidemiologic research
    • Moride Y, Abenhaim L., Evidence of the depletion of susceptibles effect in non-experimental pharmacoepidemiologic research. J Clin Epidemiol. 1994; 47: 731-7.
    • (1994) J Clin Epidemiol. , vol.47 , pp. 731-737
    • Moride, Y.1    Abenhaim, L.2
  • 51
    • 0029823520 scopus 로고    scopus 로고
    • Bone mineral density in women with depression
    • Michelson D, Stratakis C, Hill L, et al. Bone mineral density in women with depression. N Eng J Med. 1996; 355: 1176-81.
    • (1996) N Eng J Med. , vol.355 , pp. 1176-1181
    • Michelson, D.1    Stratakis, C.2    Hill, L.3
  • 53
    • 0027535467 scopus 로고
    • The incidence of hip fracture in Europe
    • Kanis JA., The incidence of hip fracture in Europe. Osteoporos Int. 1993; 3: 10-5.
    • (1993) Osteoporos Int. , vol.3 , pp. 10-15
    • Kanis, J.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.