Estrogen and its receptor enhance mechanobiological effects in compressed bone mesenchymal stem cells

Cells Tissues Organs

Volumn 195, Issue 5, 2012, Pages 400-413

  Zhang, Min ^a   Chen, Fa Ming ^a   Wang, An Hui ^a   Chen, Yong Jin ^a   Lv, Xin ^a   Wu, Shun ^a   Zhao, Rui Ni ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Bone mesenchymal stem cells; Estrogen receptor; F actin; Pressure; Rat

Indexed keywords

ALKALINE PHOSPHATASE; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; F ACTIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE; BONE DEVELOPMENT; BONE MARROW CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CELL ISOLATION; CELL LINEAGE; CELL PROLIFERATION; CELL STRUCTURE; CELL ULTRASTRUCTURE; CYTOCHEMISTRY; CYTOSKELETON; ENZYME ACTIVITY; ENZYME KINETICS; FEMALE; MECHANICAL STIMULATION; MECHANICAL STRESS; MESENCHYMAL STEM CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

ACTINS; ANIMALS; BONE MARROW CELLS; ESTROGENS; FEMALE; HUMANS; IMMUNOPHENOTYPING; MESENCHYMAL STROMAL CELLS; OSTEOGENESIS; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 84859896601     PISSN: 14226405     EISSN: 14226421     Source Type: Journal    
DOI: 10.1159/000328003     Document Type: Article

References (59)

1. Adams, G.B., K.T. Chabner, I.R. Alley, D.P. Olson, Z.M. Szczepiorkowski, M.C. Poznansky, C.H. Kos, M.R. Pollak, E.M. Brown, D.T. Scadden (2006) Stem cell engraftment at the endosteal niche is specified by the calciumsensing receptor. Nature 439: 599-603. (Pubitemid 43185384)
2. Arnsdorf, E.J., P. Tummala, R.Y. Kwon, C.R. Jacobs (2009) Mechanically induced osteogenic differentiation - the role of RhoA, ROCKII and cytoskeletal dynamics. J Cell Sci 122: 546-553.
3. Chen, Y.J., M. Zhang, J.J. Wang (2007) Study on the effects of mechanical pressure to the ultrastructure and secretion ability of mandibular condylar chondrocytes. Arch Oral Biol 52: 173-181. (Pubitemid 44920207)
4. Cheng, S.L., J.W. Yang, L. Rifas, S.F. Zhang, L.V. Avioli (1994) Differentiation of human bone-marrow osteogenic stromal cells in vitro - induction of the osteoblast phenotype by dexamethasone. Endocrinology 134: 277-286. (Pubitemid 24021999)
5. Chigira, M. (1986) Internal pressure and oxygen tension of bone tumors and tumorous conditions. Arch Orthop Trauma Surg 105: 326-331. (Pubitemid 17065567)
6. Chowdhury, F., S. Na, D. Li, Y.C. Poh, T.S. Tanaka, F. Wang, N. Wang (2010) Material properties of the cell dictate stress-induced spreading and differentiation in embryonic. Nat Mater 9: 82-88.
7. Dauvois, S., R. White, M.G. Parker (1993) The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling. J Cell Sci 106: 1377-1388. (Pubitemid 24018422)
8. Diederichs, S., F. Freiberger, G.M. van (2009) Effects of repetitive and short time strain in human bone marrow stromal cells. J Biomed Mater Res Part A 88: 907-915.
9. Discher, D.E., D.J. Mooney, P.W. Zandstra (2009) Growth factors, matrices, and forces combine and control stem cells. Science 324: 1673-1677.
10. Fan, P., J. Wang, R.J. Santen, W. Yue (2007) Longterm treatment with tamoxifen facilitates translocation of estrogen receptor alpha out of the nucleus and enhances its interaction with EGFR in MCF-7 breast cancer cells. Cancer Res 67: 1352-1360.
11. Frenkel, B., A. Hong, S.K. Baniwal, G.A. Coetzee, C. Ohlsson, O. Khalid, Y. Gabet (2010) Regulation of adult bone turnover by sex steroids. J Cell Physiol 224: 305-310.
12. Friedl, G., H. Schmidt, I. Rehak, G. Kostner, K. Schauenstein, R. Windhager (2007) Undifferentiated human mesenchymal stem cells (hMSCs) are highly sensitive to mechanical strain: Transcriptionally controlled early osteo- chondrogenic response invitro. Osteoarthr Cartilage 15: 1293-1300. (Pubitemid 350029038)
13. Frost, H.M. (1999) On the estrogen-bone relationship and postmenopausal bone loss: A new model. J Bone Miner Res 14: 1473-1477. (Pubitemid 29416672)
14. Ghazanfari, S., M. Tafazzoli-Shadpour, M.A. Shokrgozar (2009) Effects of cyclic stretch on proliferation of mesenchymal stem cells and their differentiation to smooth muscle cells. Biochem Biophys Res Commun 383: 601-605.
15. Gopalakrishnan, V., R.C. Vignesh, J. Arunakaran, M.M. Aruldhas, N. Srinivasan (2006) Effects of glucose and its modulation by insulin and estradiol on BMSC differentiation into osteoblastic lineages. Biochem Cell Biol 84: 93-101.
16. Hoemann, C.D., H. El-Gabalawy, M.D. McKee (2009) In vitro osteogenesis assays: Influence of the primary cell source on alkaline phosphatase activity and mineralization. Pathol Biol 57: 318-323.
17. Huang, C.Y., K.L. Hagar, L.E. Frost, Y. Sun, H.S. Cheung (2004) Effects of cyclic compressive loading on chondrogenesis of rabbit bonemarrow derived mesenchymal stem cells. Stem Cells 22: 313-323. (Pubitemid 38736615)
18. Huang, C.Y., P.M. Reuben, H.S. Cheung (2005) Temporal expression patterns and corresponding protein inductions of early responsive genes in rabbit bone marrow-derived mesenchymal stem cells under cyclic compressive loading. Stem Cells 23: 1113-1121. (Pubitemid 41377727)
19. Huang, Y., X. Jia, K. Bai, X. Gong, Y. Fan (2010) Effect of fluid shear stress on cardiomyogenic differentiation of rat bone marrow mesenchymal stem cells. Arch Med Res 41: 497-505.
20. Ingber, D.E. (2002) Mechanical signaling and the cellular response to extracellular matrix in angiogenesis and cardiovascular physiology. Circ Res 91: 877-887. (Pubitemid 35373587)
21. Janssens, S., C. Dubois J., Bogaert, K. Theunissen, C. Deroose, W. Desmet, M. Kalantzi, L. Herbots, P. Sinnaeve, J. Dens, J. Maertens, F. Rademakers, S. Dymarkowski, O. Gheysens, J. Van Cleemput, G. Bormans, J. Nuyts, A. Belmans, L. Mortelmans, M. Boogaerts, F. Van de Werf (2006) Autologous bone marrow- derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: Double-blind, randomised controlled trial. Lancet 367: 113-121. (Pubitemid 43077127)
22. Kemp, K.C., J. Hows, C. Donaldson (2005) Bone marrow-derived mesenchymal stem cells. Leuk Lymphoma 46: 1531-1544. (Pubitemid 41700985)
23. Kobayashi, N., T. Yasu, H. Ueba, M. Sata, S. Hashimoto, M. Kuroki, M. Saito, M. Kawakami (2004) Mechanical stress promotes the expression of smooth muscle-like properties in marrow stromal cells. Exp Hematol 232: 1238-1345.
24. Koike, M., H. Shimokawa, Z. Kanno, K. Ohya, K. Soma (2005) Effects of mechanical strain on proliferation and differentiation of bone marrow stromal cells line ST2. J Bone Miner Metab 23: 219-225. (Pubitemid 40603204)
25. Kreke, M.R., L.A. Sharp, Y.W. Lee, A.S. Goldstein (2008) Effect of intermittent shear stress on mechanotransductive signaling and osteoblastic differentiation of bone marrow stromal cells. Tissue Eng Part A 14: 529-537. (Pubitemid 351520460)
26. Kurpinski, K., J. Park, R.G. Thakar, S. Li (2006) Regulation of vascular smooth muscle cells and mesenchymal stem cells by mechanical strain. Mol Cell Biomech 3: 21-34. (Pubitemid 44803559)
27. Lee, K., H. Jessop, R. Suswillo, G. Zaman, L. Lanyon (2003) Endocrinology: Bone adaptation requires oestrogen receptor -. Nature 424: 389-391.
28. Leskelä, H.V., A. Olkku, S. Lehtonen, A. Mahonen, J. Koivunen, M. Turpeinen, J. Uusitalo, O. Pelkonen, L. Kangas, K. Selander, P. Lehenkari (2006) Estrogen receptor alpha genotype confers interindividual variability of response to estrogen and testosterone in mesenchymal-stem-cell-derived osteoblasts. Bone 39: 1026-1034. (Pubitemid 44528379)
29. Liao, Q.C., Y.L. Li, Y.F. Qin, L.D. Quarles, K.K. Xu, R. Li, H.H. Zhou, Z.S. Xiao (2008) Inhibition of adipocyte differentiation by phytoestrogen genistein through a potential downregulation of extracellular signal-regulated kinases 1/2 activity. J Cell Biochem 104: 1853-1864.
30. Lunde, K., S. Solheim, S. Aakhus, H. Arnesen, M. Abdelnoor, T. Egeland, K. Endresen, A. Ilebekk, A. Mangschau, J.G. Fjeld, H.J. Smith, E. Taraldsrud, H.K. Grøgaard, R. Bjørnerheim, M. Brekke, C. Müller, E. Hopp, A. Ragnarsson, J.E. Brinchmann, K. Forfang (2006) Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction. N Engl J Med 355: 1199-1209. (Pubitemid 44427444)
31. Marsh, M.E., A.M. Munne, J.J. Vogel, Y.Q. Cui, R.T. Franceschi (1995) Mineralization of bone-like extracellular-matrix in the absence of functional osteoblasts. J Bone Miner Res 10: 1635-1643.
32. McBeath, R., D.M. Pirone, C.M. Nelson, K. Bhadriraju, C.S. Chen (2004) Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev Cell 6: 483-495. (Pubitemid 38456178)
33. Meirelles Lda, S., N.B. Nardi (2003) Murine marrow- derived mesenchymal stem cell: Isolation, in vitro expansion, and characterization. Br J Haematol 123: 702-711. (Pubitemid 37468069)
34. Min, Z., O. Takahiro, C. Yongjin, L.v. Xin, W. Shun, S. Hong, Z. Ruini, W. Yibing (2009). Effects of condylar elastic properties to temporomandibular joint stress. J Biomed Biotechnol DOI: 10.1155/2009/509848
35. Miyanishi, K., M.C. Trindade, D.P. Lindsey, G.S. Beaupré, D.R. Carter, S.B. Goodman, D.J. Schurman, R.L. Smith (2006) Dose- and time-dependent effects of cyclic hydrostatic pressure on transforming growth factor-induced chondrogenesis by adult human mesenchymal stem cells in vitro. Tissue Eng 12: 2253-2262. (Pubitemid 44734983)
36. Mosmann, T. (1983) Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63. (Pubitemid 14203433)
37. Okazaki, R., D. Inoue, M. Shibata, M. Saika, S. Kido, H. Ooka, H. Tomiyama, Y. Sakamoto, T. Matsumoto (2002) Estrogen promotes early osteoblast differentiation and inhibits adipocyte differentiation in mouse bone marrow stromal cell lines that express estrogen receptor (ER) - or ° . Endocrinology 43: 2349-2356. (Pubitemid 34521581)
38. Ongphiphadhanakul, B., S. Chanprasertyothin, P. Payattikul, S. Saetung, N. Piaseu, L. Chailurkit, R. Rajatanavin (2001) Association of a G2014A transition in exon 8 of the estrogen receptor -gene with postmenopausal osteoporosis. Osteoporos Int 12: 1015-1019. (Pubitemid 34105971)
39. Patwari, P., R.T. Lee (2008) Mechanical control of tissue morphogenesis. Circ Res 103: 234-243.
40. Pena, S.D. (1980) A new technique for the visualization of the cytoskeleton in cultured fibroblasts with Coomassie blue R250. Cell Biol Int Rep 4: 149-153. (Pubitemid 10106500)
41. Pittenger, M.F., A.M. Mackay, S.C. Beck, R.K. Jaiswal, R. Douglas, J.D. Mosca, M.A. Moorman, D.W. Simonetti, S. Craig, D.R. Marshak (1999) Multilineage potential of adult human mesenchymal stem cells. Science 284: 143-147. (Pubitemid 29282067)
42. Potier, E., J. Noailly, K. Ito (2010) Directing bone marrow-derived stromal cell function with mechanics. J Biomech 43: 807-817.
43. Qi, M.C., J. Hu, S.J. Zou, H.Q. Chen, H.X. Zhou, L.C. Han (2008) Mechanical strain induces osteogenic differentiation: Cbfa1 and Ets-1 expression in stretched rat mesenchymal stem cells. Int J Oral Max Surg 37: 453-458. (Pubitemid 351608125)
44. Saxon, L.K., C.H. Turner (2005) Estrogen receptor: The antimechanostat? Bone 36: 185-192.
45. Song, G., Y. Ju, H. Soyama, T. Ohashi, M. Sato (2007) Regulation of cyclic longitudinal mechanical stretch on proliferation of human bone marrow mesenchymal stem cells. Mol Cell Biomech 4: 201-210. (Pubitemid 351493007)
46. Stiehler, M., C. Bunger, A. Baatrup, M. Lind, M. Kassem, T. Mygind (2009) Effect of dynamic 3-D culture on proliferation, distribution, and osteogenic differentiation of human mesenchymal stem cells. J Biomed Mater Res A 89: 96-107.
47. Sun, L., M. Cui, Z. Wang, X. Feng, J. Mao, P. Chen, M. Kangtao, F. Chen, C. Zhou (2007) Mesenchymal stem cells modified with angiopoietin- 1 improve remodeling in a rat model of acute myocardial infarction. Biochem Biophys Res Commun 357: 779-784. (Pubitemid 46653847)
48. Sung, J.H., H.M. Yang, J.B. Park, G.S. Choi, J.W. Joh, C.H. Kwon, J.M. Chun, S.K. Lee, S.J. Kim (2008) Isolation and characterization of mouse mesenchymal stem cells. Transplantation Proceedings 40: 2649-2654.
49. Syed, F., S. Khosla (2005) Mechanisms of sex steroid effects on bone. Biochem Biophys Res Commun 328: 688-696. (Pubitemid 40214350)
50. Takeda, S. (2008) Central control of bone remodelling. J Neuroendocrinol 20: 802-807. (Pubitemid 351858732)
51. Uemura, R., M. Xu, N. Ahmad, M. Ashraf (2006) Bone marrow stem cells prevent left ventricular remodeling of ischemic heart through paracrine signaling. Circ Res 98: 1414-1421. (Pubitemid 43948066)
52. Wang, J.H., P. Goldschmidt-Clermont, J. Wille, F.C. Yin (2001) Specificity of endothelial cell reorientation in response to cyclic mechanical stretching. J Biomech 34: 1563-1572. (Pubitemid 33041372)
53. Wang, N., I.M. Tolic-Nørrelykke, J. Chen, S.M. Mijailovich, J.P. Butler, J.J. Fredberg, D. Stamenovic (2002) Cell prestress. I. Stiffness and prestress are closely associated in adherent contractile cells. Am J Physiol Cell Physiol 282: C606-C616. (Pubitemid 34663177)
54. Yazawa, H., B. Zimmermann, Y. Asami, J.P. Bernimoulin (2005) Simvastatin promotes cell metabolism, proliferation, and osteoblastic differentiation in human periodontal ligament cells. J Periodontol 76 : 295-302. (Pubitemid 40542260)
55. Yousefian, J., F. Firouzian, J. Shanfeld, P. Ngan, R. Lanese, Z. Davidovitch (1995) A new experimental model for studying the response of periodontal ligament cells to hydrostatic pressure. Am J Orthod Dentofacial Orthop 108: 402-409.
56. Zeiter, S., P. Lezuo, K. Ito (2009) Effect of TGF - 1, BMP-2 and hydraulic pressure on chondrogenic differentiation of bovine bone marrow mesenchymal stromal cells. Biorheology 46: 45-55.
57. Zhang, M., J.J. Wang, Y.J. Chen (2006) Effects of mechanical pressure on intracellular calcium release channel and cytoskeletal structure in rabbit mandibular condylar chondrocytes. Life Sci 78: 2480-2487.
58. Zhang, M., Y.J. Chen, T. Ono, J.J. Wang (2008) Crosstalk between integrin and G protein pathways involved in mechanotransduction in mandibular condylar chondrocytes under pressure. Arch Biochem Biophys 474: 102-108.
59. Zhang, M., T. Ono, Y.J. Chen, X. Lv, S. Wu, H. Song, R.N. Zhao, Y.B. Wang (2009) Effects of condylar elastic properties to temporomandibular joint stress. J Biomed Biotechnol DOI 10.1155/2009/509848.