-
1
-
-
8544257029
-
The 118 A > G polymorphism in the human mu-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease
-
Klepstad P, Rakvag TT, Kaasa S, et al. The 118 A > G polymorphism in the human mu-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease. Acta Anaesthesiol Scand 2004; 48: 1232-1239.
-
(2004)
Acta Anaesthesiol Scand
, vol.48
, pp. 1232-1239
-
-
Klepstad, P.1
Rakvag, T.T.2
Kaasa, S.3
-
2
-
-
20444451123
-
The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients
-
Rakvag TT, Klepstad P, Baar C, et al. The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients. Pain 2005; 116: 73-78.
-
(2005)
Pain
, vol.116
, pp. 73-78
-
-
Rakvag, T.T.1
Klepstad, P.2
Baar, C.3
-
3
-
-
39749183472
-
Pharmacogenetics of morphine: Potential implications in sickle cell disease
-
Darbari DS, Minniti CP, Rana S, van den Anker J. Pharmacogenetics of morphine: Potential implications in sickle cell disease. Am J Hematol 2008; 83: 233-236.
-
(2008)
Am J Hematol
, vol.83
, pp. 233-236
-
-
Darbari, D.S.1
Minniti, C.P.2
Rana, S.3
van den Anker, J.4
-
4
-
-
84859913596
-
Sickle cell pain: Biology, etiology, and treatment
-
In: Editor: Cambridge University-Press (New-York).
-
Ballas SK, Eckman JR. Sickle cell pain: Biology, etiology, and treatment. In: Editor: Cambridge University-Press (New-York). Disorders of Hemoglobin: Genetics, Pathophysiology and Clinical Management. 2009. pp 497-524.
-
(2009)
Disorders of Hemoglobin: Genetics, Pathophysiology and Clinical Management
, pp. 497-524
-
-
Ballas, S.K.1
Eckman, J.R.2
-
6
-
-
33744787363
-
Pharmacokinetics and toxicity of docetaxel: role of CYP3A, MDR1, and GST polymorphisms
-
Tran A, Jullien V, Alexandre J, et al. Pharmacokinetics and toxicity of docetaxel: role of CYP3A, MDR1, and GST polymorphisms. Clin Pharmacol Ther 2006; 79: 570-580.
-
(2006)
Clin Pharmacol Ther
, vol.79
, pp. 570-580
-
-
Tran, A.1
Jullien, V.2
Alexandre, J.3
-
7
-
-
39749110077
-
UGT2B7 promoter variant -840G>A contributes to the variability in hepatic clearance of morphine in patients with sickle cell disease
-
Darbari DS, van Schaik RH, Capparelli EV, et al. UGT2B7 promoter variant -840G>A contributes to the variability in hepatic clearance of morphine in patients with sickle cell disease. Am J Hematol 2008; 83: 200-202.
-
(2008)
Am J Hematol
, vol.83
, pp. 200-202
-
-
Darbari, D.S.1
van Schaik, R.H.2
Capparelli, E.V.3
-
8
-
-
1542286160
-
A novel functional polymorphism in the uridine diphosphate-glucuronosyltransferase 2B7 promoter with significant impact on promoter activity
-
Duguay Y, Baar C, Skorpen F, Guillemette C. A novel functional polymorphism in the uridine diphosphate-glucuronosyltransferase 2B7 promoter with significant impact on promoter activity. Clin Pharmacol Ther 2004; 75: 223-233.
-
(2004)
Clin Pharmacol Ther
, vol.75
, pp. 223-233
-
-
Duguay, Y.1
Baar, C.2
Skorpen, F.3
Guillemette, C.4
-
9
-
-
38349132802
-
The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype
-
Gaedigk A, Simon SD, Pearce RE, Bradford LD, et al. The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype. Clin Pharmacol Ther 2008; 83: 234-242.
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 234-242
-
-
Gaedigk, A.1
Simon, S.D.2
Pearce, R.E.3
Bradford, L.D.4
-
10
-
-
0027136288
-
Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine
-
Johansson I, Lundqvist E, Bertilsson L, et al. Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine. Proc Natl Acad Sci USA 1993; 90: 11825-11829.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11825-11829
-
-
Johansson, I.1
Lundqvist, E.2
Bertilsson, L.3
-
11
-
-
25144433260
-
Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability
-
Wang D, Johnson AD, Papp AC, et al. Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability. Pharmacogenet Genomics 2005; 15: 693-704.
-
(2005)
Pharmacogenet Genomics
, vol.15
, pp. 693-704
-
-
Wang, D.1
Johnson, A.D.2
Papp, A.C.3
-
12
-
-
40949150784
-
Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief
-
Campa D, Gioia A, Tomei A, et al. Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief. Clin Pharmacol Ther 2008; 83: 559-566.
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 559-566
-
-
Campa, D.1
Gioia, A.2
Tomei, A.3
-
13
-
-
0036902461
-
Pharmacokinetic modelling of morphine, morphine-3-glucuronide and morphine-6-glucuronide in plasma and cerebrospinal fluid of neurosurgical patients after short-term infusion of morphine
-
Meineke I, Freudenthaler S, Hofmann U, et al. Pharmacokinetic modelling of morphine, morphine-3-glucuronide and morphine-6-glucuronide in plasma and cerebrospinal fluid of neurosurgical patients after short-term infusion of morphine. Br J Clin Pharmacol 2002; 54: 592-603.
-
(2002)
Br J Clin Pharmacol
, vol.54
, pp. 592-603
-
-
Meineke, I.1
Freudenthaler, S.2
Hofmann, U.3
-
14
-
-
3042772026
-
Identification of functionally variant MDR1 alleles among European Americans and African Americans
-
Kim RB, Leake BF, Choo EF, et al. Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin Pharmacol Ther 2001; 70: 189-199.
-
(2001)
Clin Pharmacol Ther
, vol.70
, pp. 189-199
-
-
Kim, R.B.1
Leake, B.F.2
Choo, E.F.3
-
15
-
-
10744222684
-
Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene
-
Kroetz DL, Pauli-Magnus C, Hodges LM, et al. Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene. Pharmacogenetics 2003; 13: 481-494.
-
(2003)
Pharmacogenetics
, vol.13
, pp. 481-494
-
-
Kroetz, D.L.1
Pauli-Magnus, C.2
Hodges, L.M.3
-
16
-
-
0037261291
-
Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers
-
Skarke C, Darimont J, Schmidt H, et al. Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers. Clin Pharmacol Ther 2003; 73: 107-121.
-
(2003)
Clin Pharmacol Ther
, vol.73
, pp. 107-121
-
-
Skarke, C.1
Darimont, J.2
Schmidt, H.3
-
17
-
-
34249794271
-
Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene
-
Reyes-Gibby CC, Shete S, Rakvag T, et al. Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene. Pain 2007; 130: 25-30.
-
(2007)
Pain
, vol.130
, pp. 25-30
-
-
Reyes-Gibby, C.C.1
Shete, S.2
Rakvag, T.3
-
18
-
-
80855133522
-
Pharmacokinetics, pharmacodynamics, and pharmacogenetics of hydroxyurea treatment for children with sickle cell anemia
-
Ware RE, Despotovic JM, Mortier NA, et al. Pharmacokinetics, pharmacodynamics, and pharmacogenetics of hydroxyurea treatment for children with sickle cell anemia. Blood 2011; 118: 4985-4991.
-
(2011)
Blood
, vol.118
, pp. 4985-4991
-
-
Ware, R.E.1
Despotovic, J.M.2
Mortier, N.A.3
-
20
-
-
32944456152
-
Current evidence for a genetic modulation of the response to analgesics
-
Lotsch J, Geisslinger G. Current evidence for a genetic modulation of the response to analgesics. Pain 2006; 121: 1-5.
-
(2006)
Pain
, vol.121
, pp. 1-5
-
-
Lotsch, J.1
Geisslinger, G.2
-
21
-
-
34547644659
-
Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication
-
Kirchheiner J, Schmidt H, Tzvetkov M, et al. Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication. Pharmacogenomics J 2007; 7: 257-265.
-
(2007)
Pharmacogenomics J
, vol.7
, pp. 257-265
-
-
Kirchheiner, J.1
Schmidt, H.2
Tzvetkov, M.3
-
22
-
-
0028844757
-
Homologous unequal cross-over involving a 2.8 kb direct repeat as a mechanism for the generation of allelic variants of human cytochrome P450 CYP2D6 gene
-
Steen VM, Molven A, Aarskog NK, Gulbrandsen AK. Homologous unequal cross-over involving a 2.8 kb direct repeat as a mechanism for the generation of allelic variants of human cytochrome P450 CYP2D6 gene. Hum Mol Genet 1995; 4: 2251-2257.
-
(1995)
Hum Mol Genet
, vol.4
, pp. 2251-2257
-
-
Steen, V.M.1
Molven, A.2
Aarskog, N.K.3
Gulbrandsen, A.K.4
-
23
-
-
33745191461
-
Random mating populations: Hardy-Weinberg principle
-
Editor: Blackwell Publishing (Malden, MA, USA).
-
Allendorf FW, Luikart G. Random mating populations: Hardy-Weinberg principle. Editor: Blackwell Publishing (Malden, MA, USA). Conservation and the genetics of populations. 2007. pp 93-112.
-
(2007)
Conservation and the genetics of populations
, pp. 93-112
-
-
Allendorf, F.W.1
Luikart, G.2
-
24
-
-
0035071957
-
A new statistical method for haplotype reconstruction from population data
-
Stephens M, Smith NJ, Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 2001; 68: 978-989.
-
(2001)
Am J Hum Genet
, vol.68
, pp. 978-989
-
-
Stephens, M.1
Smith, N.J.2
Donnelly, P.3
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