Immunohistochemical expression of Rho GTPases in ameloblastomas

Journal of Oral Pathology and Medicine

Volumn 41, Issue 5, 2012, Pages 400-407

  Modolo, Filipe ^a   Biz, Michelle Tillmann ^a   de Sousa, Suzana Machado ^b   Fachinelli, Rodolfo de Lima ^c   Crema, Virgínia Oliveira ^c  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c FEDERAL UNIVERSITY OF TRIÂNGULO MINEIRO   (Brazil)

Author keywords

Ameloblastoma; Cytoskeleton; GTPases

Indexed keywords

BIOTIN; PARAFFIN; PROTEIN CDC42; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOB GUANINE NUCLEOTIDE BINDING PROTEIN;

AMELOBLASTOMA; ARTICLE; CANCER INVASION; CELL COUNT; ENZYME LOCALIZATION; EPITHELIUM CELL; FOLLICULAR AMELOBLASTOMA; HUMAN; IMMUNOHISTOCHEMISTRY; PHENOTYPE; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOLID AMELOBLASTOMA; UNICYSTIC AMELOBLASTOMA;

EID: 84859864537     PISSN: 09042512     EISSN: 16000714     Source Type: Journal    
DOI: 10.1111/j.1600-0714.2011.01108.x     Document Type: Article

References (56)

1. Papagerakis P, Peuchmaur M, Hotton D, et al. Aberrant gene expression in epithelial cells of mixed odontogenic tumors. J Dent Res 1999; 78: 20-30.
2. Barnes L, Everson JW, Reichart P, Sidransky D. Pathology and genetics of head and neck tumours. Lyon: IARC Press, 2005; 327.
3. Alaeddini M, Etemad-Moghadam S, Baghaii F. Comparative expression of calretinin in selected odontogenic tumours: a possible relationship to histogenesis. Histopathol 2008; 52: 299-304.
4. Mina M, Kollar EJ. The induction of odontogenesis in non-dental mesenchyme combined with early murine mandibular arch epithelium. Arch Oral Biol 1987; 32: 123-7.
5. Nishikawa S, Kitamura H. Microtubules, intermediate filaments, and actin filaments in the odontoblast of rat incisor. Anat Rec 1987; 219: 144-51.
6. Diekwisch T. Loclaization of microfilaments and microtubules during dental development in the rat. Acta Histochem Suppl 1989; 37: 209-12.
7. Ten Cate R. Oral histology: development, structure, and function. St. Louis: Mosby Year Book, 1998; 497.
8. Katchburian E, Arana-Chavez V. Histologia e embriologia oral. São Paulo: Panamericana, 2004; 372.
9. Gardner D, Heikinheimo K, Shear M, et al. Ameloblastomas. In: BARNES L, EVERSON J, REICHART P, SIDRANSKY D eds. World health organization classification of tumours pathology and genetics of head and neck tumours. Lyon: IARC Press, 2005; 296-300.
10. Kumamoto H, Ooya K. Expression of survivin and X chromosome-linked inhibitor of apoptosis protein in ameloblastomas. Virchows Arch 2004; 444: 164-70.
11. Jääskeläinen K, Jee KJ, Leivo I, et al. Cell proliferation and chromosomal changes in human ameloblastoma. Cancer Genet Cytogenet 2002; 136: 31-7.
12. Heikinheimo K, Jee KJ, Niini T, et al. Gene expression profiling of ameloblastoma and human tooth germ by means of a cDNA microarray. J Dent Res 2002; 81: 525-30.
13. Fukata M, Nakagawas M, Kaibuchi K. Roles of Rho-family GTPases in cell polarization and directional migration. Curr Opin Cell Biol 2003; 15: 590-7.
14. Etienne-Manneville S, Hall A. Rho GTPases in cell biology. Nature 2002; 420: 629-35.
15. Heasman SJ, Ridley AJ. Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nature Rev Mol Cell Biol 2008; 9: 690-701.
16. Fromigue O, Hamidouhe Z, Marie PJ. Blockade of the RhoA-JNK-c-Jun-MMP2 cacade by atorvastatin reduces osteosarcoma cell invasion. J Biol Chem 2008; 283: 30549-56.
17. Ridley AJ, Schwartz MA, Burridge K, et al. Cell migration: integrating signals from front to back. Science 2003; 302: 1704-9.
18. Watabe-Uchida M, Gove EE, Van Aelst L. Regulators of Rho GTPases in neuronal development. J Neurosci 2006; 26: 10633-5.
19. Burridge K, Wennerberg K. Rho and Rac take center stage. Cell 2004; 93: 1077-85.
20. Harper EG, Alvares SM, Carter WG. Wounding activates p38 map kinase and activation transcription factor 3 in leading keratinocytes. J Cell Sci 2005; 118: 3471-85.
21. Faccio R, Novack DV, Zallone A, et al. Dynamic changes in the osteoclast cytoskeleton in response to growth factors and cell attachment are controlled by beta3 integrin. J Cell Biol 2003; 162: 499-509.
22. Calaf G, Roy D, Hei T. Immunochemical analysis of protein expression in breast epithelial cells transformed by estrogens and high linear energy transfer (LET) radiation. Histochem Cell Biol 2005; 124: 261-74.
23. Karlsson R, Pedersen ED, Wang Z, et al. Rho GTPase function in tumorigenesis. Biochim Biophys Acta - Reviews on Cancer 2009; 1796: 91-8.
24. Fromm C, Coso OA, Montaner S, et al. The small GTP-binding protein Rho links G protein-coupled receptors and G alpha12 to the serum response element and to cellular transformation. Proc Natl Acad Sci USA 1997; 94: 10098-103.
25. Crema VN, Fossati A, Hamassaki DN, et al. Distribution of small Rho GTPases in the developing rat submandibular gland. J Mol Histol 2008; 39: 519-25.
26. Boland GM, Perkins G, Hall DJ, et al. Wnt 3a promotes proliferation and supesses osteogenic differentiation of adult mesenchymal stem cells. J Cell Biochem 2004; 93: 1210-30.
27. Hu B, Nadiri A, Boop-Kuchler S, et al. Dental Epithelial histo-morphogenesis in the mouse: positional information versus cell history. Arch Oral Biol 2005; 50: 131-6.
28. Thesleff I, Jernvall J. The enamel Knot: a putative signaling center regulating tooth development. Cold Spring Harb Symp Quant Biol 1997; 62: 257-67.
29. Alberts B, Johnson A, Lewis J, et al. Molecular biology of the cell. New York: Garland Science, 2004.
30. Iezzi GMD, Piattelli AMD, Rubini CMD, et al. Expression of Transforming Growth Factor [beta]1 in Ameloblastomas. J Craniofac Surg 2008; 19: 1618-21.
31. Kim H, Kang M, Lee S-A, et al. TM4SF5 accelerates G1/S phase progression via cytosolic p27Kip1 expression and RhoA activity. Biochim Biophys Acta - Mol Cell Res 2010; 1803: 975-82.
32. Frame MC, Brunton VG. Advances in Rho-dependent actin regulation and oncogenic transformation. Curr Opin Genet Dev 2002; 12: 36-43.
33. Biz MT, Marques MR, Crema VO, et al. GTPases RhoA and Rac1 are important for amelogenin and DSPP expression during differentiation of ameloblasts and odontoblasts. Cell Tissue Res 2010; 340: 459-70.
34. Li Y, Decker S, Yuan Z, et al. Effects of sodium fluoride on the actin cytoskeleton of murine ameloblasts. Arch Oral Biol 2005; 50: 681-8.
35. Popoff MR, Geny B. Multifaceted role of Rho, Rac, Cdc42 and Ras in intercellular junctions, lessons from toxins. Biochim Biophys Acta - Biomembranes 2009; 1788: 797-812.
36. Bello I, Soini Y, Slootweg P, et al. Claudins 1, 4, 5, 7 and occludin in ameloblastomas and developing human teeth. J Oral Pathol Med 2007; 36: 48-54.
37. Martin KH, Slack JK, Boerner SA, et al. Integrin Connections Map: to Infinity and Beyond. Science 2002; 296: 1652-3.
38. Danen EHJ, Van Rheenen J, Franken W, et al. Integrins control motile strategy through a Rho-cofilin pathway. J Cell Biol 2005; 169: 515-26.
39. Modolo F, Martins MT, Loducca SVL, et al. Expression of integrin subunits a2, a3, a5, av, b1, b3 and b4 in different histological types of ameloblastoma compared with dental germ, dental lamina and adult lining epithelium. Oral Dis 2004; 10: 277-82.
40. Souza Andrade ES, Miguel MCDC, De Almeida Freitas R, et al. Immunoexpression of integrins in ameloblastoma, adenomatoid odontogenic tumor, and human tooth germs. Int J Surg Pathol 2008; 16: 277-85.
41. Wheeler AP, Ridley AJ. RhoB affects macrophage adhesion, integrin expression and migration. Exp Cell Res 2007; 313: 3505-16.
42. D'amico G, Robinson SD, Germain M, et al. Endothelial-Rac1 is not required for tumor angiogenesis unless alphavbeta3 integrin is absent. PLoS ONE 2010; 5: e9766.
43. Keely PJ, Westwick JK, Whitehead IP, et al. Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K. Nature 1997; 390: 632-6.
44. Lebowitz PF, Du W, Prendergast GC. Prenylation of RhoB is required for its cell transforming function but not its ability to activate serum response element-dependent transcription. J Biol Chem 1997; 272: 16093-5.
45. Narumiya S, Tanji M, Ishizaki T. Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion. Cancer Metastasis Rev 2009; 28: 65-76.
46. Arnaud M, Mzali R, Gesbert F, et al. Interaction of the tyrosine phosphatase SHP-2 with Gab2 regulates Rho-dependent activation of the c-fos serum response element by interleukin-2. Biochem J 2004; 382: 545-56.
47. Kumamoto H, Ooya K. Expression of tumor necrosis factor alfa, TNF-related apoptosis-inducing ligand, and their associated molecules in ameloblastomas. J Oral Pathol Med 2005; 34: 287-94.
48. Kakiashvili E, Speight P, Waheed F, et al. GEF-H1 mediates tumor necrosis Factor-α- induced rho activation and myosin phosphorylation. J Biol Chem 2009; 284: 11454-66.
49. Goto K, Chiba Y, Sakai H, et al. Mechanism of inhibitory effect of prednisolone on RhoA upregulation in human bronchial smooth muscle cells. Biol Pharm Bull 2010; 33: 710-3.
50. Kumamoto H, Takahashi N, Ooya K. K-Ras gene status and expression of Ras/mitogen-activated protein kinase (MAPK) signaling molecules in ameloblastomas. J Oral Pathol Med 2004; 33: 360-7.
51. Sauzeau V, Berenjeno IM, Citterio C, et al. A transcriptional cross-talk between RhoA and c-Myc inhibits the RhoA/Rock-dependent cytoskeleton. Oncogene 2010; 29: 3781-92.
52. Kumamoto H, Kinouchi Y, Ooya K. Telomerase activity and telomerase reverse transcriptase (TERT) expression in ameloblastomas. J Oral Pathol Med 2001; 30: 231-6.
53. Barboza CAG, Pinto LP, Freitas RDA, et al. Proliferating cell nuclear antigen (PCNA) and p53 protein expression in ameloblastoma and adenomatoid adontogenic tumor. Braz Dent J 2005; 16: 56-61.
54. Kumamoto H, Izutsu T, Ohki K, et al. p53 gene status and expression of p53, MDM2, and p14ARF proteins in ameloblastomas. J Oral Pathol Med 2004; 33: 292-9.
55. Vasilaki E, Papadimitriou E, Tajadura V, et al. Transcriptional regulation of the small GTPase RhoB gene by TGF{beta}-induced signaling pathways. FASEB J 2010; 24: 891-905.
56. Yoneda M, Hirokawa YS, Ohashi A, et al. RhoB enhances migration and MMP1 expression of prostate cancer DU145. Exp Mol Pathol 2010; 88: 90-5.