Proliferating cell nuclear antigen (PCNA) and p53 protein expression in ameloblastoma and adenomatoid odontogenic tumor

Brazilian Dental Journal

Volumn 16, Issue 1, 2005, Pages 56-61

  Barboza, Carlos Augusto Galvão ^a   Pereira Pinto, Leão ^a   Freitas, Roseana De Almeida ^a   Costa, Antônio De Lisboa Lopes ^a   De Souza, Lélia Batista ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

Author keywords

Adenomatoid odontogenic tumor; Ameloblastoma; p53 protein; PCNA

Indexed keywords

CYCLINE; PROTEIN P53;

AMELOBLASTOMA; ANALYSIS OF VARIANCE; ARTICLE; BIOSYNTHESIS; CANCER INVASION; CLASSIFICATION; ENZYME IMMUNOASSAY; HUMAN; METABOLISM; NONPARAMETRIC TEST; ODONTOGENIC TUMOR; PATHOLOGY;

AMELOBLASTOMA; ANALYSIS OF VARIANCE; HUMANS; IMMUNOENZYME TECHNIQUES; NEOPLASM INVASIVENESS; ODONTOGENIC TUMORS; PROLIFERATING CELL NUCLEAR ANTIGEN; STATISTICS, NONPARAMETRIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 28444439902     PISSN: 01036440     EISSN: 01036440     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Gardner DG. Some current concepts on the pathology of ameloblastomas. J Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1996;82:660-669.
2. Waldron CA. Odontogenic cysts and tumors. In: Oral & Maxillofacial Pathology. Neville BW, Damm DD, Allen CM, Bouquot JE (Editors). Philadelphia: WB Saunders; 1995. p. 511-538.
3. Reichart PA, Philipsen HP, Sonner S. Ameloblastoma: biological profile of 367 cases. Eur J Cancer B Oral Oncol 1995;31B:86-99.
4. Garcia RL, Coltrera MD, Gown AM. Analysis of proliferative grade using anti-PCNA/cyclin monoclonal antibodies in fixed, embedded tissues: comparison with flow cytometric analysis. Am J Pathol 1989;134:134-139.
5. Do Carmo MA, Silva EC. Argyrophilic nucleolar organizer regions (AgNORs) in ameloblastomas and adenomatoid odontogenic tumours (AOTs). J Oral Pathol Med 1998;27:153-156.
6. Kim J, Yook JI. Immunohistochemical study on proliferating cell nuclear antigen expression in ameloblastomas. Eur J Cancer B Oral Oncol 1994;30B:126-131.
7. Meer S, Galpin JS, Altini M, Coleman H, Ali H. Proliferating cell nuclear antigen and Ki67 immunoreactivity in ameloblastomas. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;95:213-221.
8. Jãaskelainen K, Jee KJ, Leivo I, Saloniemi I, Knuutila S, Heikinheimo K Cell proliferation and chromosomal changes in human ameloblastoma. Cancer Genet Cytogene 2002;136:31-37.
9. Funaoka K, Arisue M, Kobayashi S, Iizuka T, Kohgo T, Amemiya A, Totsuka Y. Immunohistochemical detection of proliferating cell nuclear antigen (PCNA) in 23 cases of ameloblastoma. Eur J Cancer B Oral Oncol 1996;32B:328-332.
10. Kumamoto H, Kimi K, Ooya K. Detection of cell cycle-related factors in ameloblastomas. J Oral Pathol Med 2001;30:309-315.
11. Sandra F, Mitsuyasu T, Nakamura N, Shiratsuchi Y, Ohishi M. Immunohistochemical evaluation of PCNA and Ki67 in ameloblastoma. Oral Oncol 2001;37:193-198.
12. Medeiros MCS, Freitas RA, Souza LB. Análise quantitativa das regiões organizadoras nucleolares nos diversos tipos histológicos do ameloblastoma e no tumor odontogênico adenomatóide. RGO 1997;45:67-70.
13. Souza LB, Sousa CV, Pereira Pinto L. Estudo morfológico e imuno-histoquímico da membrana basal em diversos padrões histológicos do ameloblastoma. RPG Rev Pós Grad 2001;8:40-45.
14. Thompson IO, van Rensburg LJ, Phillips VM. Desmoplastic ameloblastoma: correlative histopathology, radiology and CT-MR imaging. J Oral Pathol Med 1996;25:405-410.
15. Ueno S, Mushimoto K, Shirasu R. Prognostic evaluation of ameloblastoma based on histologic and radiographic typing. J Oral Maxillofac Surg 1989;47:11-15.
16. Shivji MKK, Kenny MK, Wood RD. Proliferating cell nuclear-antigen is required for DNA excision repair. Cell 1992;69:367-374.
17. Hall PA, Levison DA, Woods AL. Yu CC, Kellock DB, Watkins JA, Barnes DM, Gillett CE, Camplejohn R, Dover R, Waseem NH, Lane DP. Proliferating cell nuclear antigen (PCNA) immu-nolocalization in paraffin sections: an index of cell proliferation with evidence of deregulated expression in some neoplasms. J Pathol 1990; 162:285-294.
18. Scott RJ, Hall PA, Haldana JS, Van Noorden S, Price Y, Lane DP, Wrigh NA. A comparison of immunohistochemical markers of cell proliferation with experimentally determined growth fraction. J Pathol 1991;165:173-178.
19. Carvalhais JN, Aguiar MCF, Araújo VC, Araújo NS, Gomez RS. p53 and MDM2 expression in odontogenic cysts and tumours. Oral Dis 1999;5:218-222.
20. Dowell SP, Ogden GR. The use of antigen retrieval for immunohistochemical detection of p53 over-expression in malignant and benign oral mucosa: a cautionary note. J Oral Pathol Med 1996;25:60-64.