-
1
-
-
33645634897
-
Substrate specificity of human kallikrein 6: Salt and glycosaminoglycan activation effects
-
DOI 10.1074/jbc.M510096200
-
Angelo, P.F., Lima, A.R., Alves, F.M., Blaber, S.I., Scarisbrick, I.A., Blaber, M., Juliano, L., and Juliano, M.A. (2006). Substrate speci ficity of human kallikrein 6: salt and glycosaminoglycan activation effects. J. Biol. Chem. 281, 3116-3126. (Pubitemid 43845921)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.6
, pp. 3116-3126
-
-
Angelo, P.F.1
Lima, A.R.2
Alves, F.M.3
Blaber, S.I.4
Scarisbrick, I.A.5
Blaber, M.6
Juliano, L.7
Juliano, M.A.8
-
2
-
-
0029929603
-
Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2
-
Bohm, S.K., Kong, W., Bromme, D., Smeekens, S.P., Anderson, D.C., Connolly, A., Kahn, M., Nelken, N.A., Coughlin, S.R., Payan, D.G., et al. (1996). Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2. Biochem. J. 314, 1009-1016. (Pubitemid 26097768)
-
(1996)
Biochemical Journal
, vol.314
, Issue.3
, pp. 1009-1016
-
-
Bohm, S.K.1
Kong, W.2
Bromme, D.3
Smeekens, S.P.4
Anderson, D.C.5
Connolly, A.6
Kahn, M.7
Nelken, N.A.8
Coughlin, S.R.9
Payan, D.G.10
Bunnett, N.W.11
-
3
-
-
3543150203
-
Human tissue kallikreins: Physiologic roles and applications in cancer
-
Borgoño, C.A., Michael, I.P., and Diamandis, E.P. (2004). Human tissue kallikreins: physiologic roles and applications in cancer. Mol. Cancer Res. 2, 257-280. (Pubitemid 39031076)
-
(2004)
Molecular Cancer Research
, vol.2
, Issue.5
, pp. 257-280
-
-
Borgono, C.A.1
Michael, I.P.2
Diamandis, E.P.3
-
4
-
-
66049125101
-
Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome
-
Briot, A., Deraison, C., Lacroix, M., Bonnart, C., Robin, A., Besson, C., Dubus, P., and Hovnanian, A. (2009). Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome. J. Exp. Med. 206, 1135-1147.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1135-1147
-
-
Briot, A.1
Deraison, C.2
Lacroix, M.3
Bonnart, C.4
Robin, A.5
Besson, C.6
Dubus, P.7
Hovnanian, A.8
-
5
-
-
78149464736
-
Par2 inactivation inhibits early production of TSLP, but not cutaneous inflammation, in Netherton syndrome adult mouse model
-
Briot, A., Lacroix, M., Robin, A., Steinhoff, M., Deraison, C., Hovnanian, A. (2010). Par2 inactivation inhibits early production of TSLP, but not cutaneous inflammation, in Netherton syndrome adult mouse model. J. Invest. Dermatol. 130, 2736-2742.
-
(2010)
J. Invest. Dermatol.
, vol.130
, pp. 2736-2742
-
-
Briot, A.1
Lacroix, M.2
Robin, A.3
Steinhoff, M.4
Deraison, C.5
Hovnanian, A.6
-
6
-
-
0014941657
-
Proteolytic enzymes initiating cell division and escape from contact inhibition of growth
-
Burger, M.M. (1970). Proteolytic enzymes initiating cell division and escape from contact inhibition of growth. Nature 227, 170-171.
-
(1970)
Nature
, vol.227
, pp. 170-171
-
-
Burger, M.M.1
-
7
-
-
0034120666
-
Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome
-
DOI 10.1038/75977
-
Chavanas, S., Bodemer, C., Rochat, A., Hamel-Teillac, D., Ali, M., Irvine, A.D., Bonafé, J.L., Wilkinson, J., Taíeb, A., Barrandon, Y., et al. (2000). Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome. Nat. Genet. 25, 141-142. (Pubitemid 30394980)
-
(2000)
Nature Genetics
, vol.25
, Issue.2
, pp. 141-142
-
-
Chavanas, S.1
Bodemer, C.2
Rochat, A.3
Hamel-Teillac, D.4
Ali, M.5
Irvine, A.D.6
Bonafe, J.-L.7
Wilkinson, J.8
Taieb, A.9
Barrandon, Y.10
Harper, J.I.11
De Prost, Y.12
Hovnanian, A.13
-
8
-
-
0016432831
-
Mitogenic activity of blood components. I. Thrombin and prothrombin
-
Chen, L.B. and Buchanan, J.M. (1975). Mitogenic activity of blood components. I. Thrombin and prothrombin. Proc. Natl. Acad. Sci. USA 72, 131-135.
-
(1975)
Proc. Natl. Acad. Sci. USA
, vol.72
, pp. 131-135
-
-
Chen, L.B.1
Buchanan, J.M.2
-
9
-
-
0036905071
-
2): Role in cell surface expression and signalling
-
DOI 10.1042/BJ20020706
-
Compton, S.J., Sandhu S., Wijesuriya S.J., and Hollenberg, M.D. (2002). Glycosylation of human proteinase-activated receptor-2 (hPAR2): role in cell surface expression and signalling. Biochem. J. 368, 495-505. (Pubitemid 35454527)
-
(2002)
Biochemical Journal
, vol.368
, Issue.2
, pp. 495-505
-
-
Compton, S.J.1
Sandhu, S.2
Wijesuriya, S.J.3
Hollenberg, M.D.4
-
10
-
-
40349108549
-
Beta-arrestins and heterotrimeric G-proteins: Collaborators and competitors in signal transduction
-
Defea, K. (2008). Beta-arrestins and heterotrimeric G-proteins: collaborators and competitors in signal transduction. Br. J. Pharmacol. 153 (Suppl. 1), S298-S309.
-
(2008)
Br. J. Pharmacol.
, vol.153
, Issue.SUPPL. 1
-
-
Defea, K.1
-
11
-
-
0034689003
-
Beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2
-
DeFea, K.A., Zalevsky, J., Thoma, M.S., Déry, O., Mullins, R.D., and Bunnett, N.W. (2000). Beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2. J. Cell Biol. 148, 1267-1281.
-
(2000)
J. Cell Biol.
, vol.148
, pp. 1267-1281
-
-
Defea, K.A.1
Zalevsky, J.2
Thoma, M.S.3
Déry, O.4
Mullins, R.D.5
Bunnett, N.W.6
-
12
-
-
78650937552
-
Kallikrein-related peptidase-8 (KLK8) is an active serine protease in human epidermis and sweat and is involved in a skin barrier proteolytic cascade
-
Eissa, A., Amodeo, V., Smith, C.R., and Diamandis, E.P. (2011). Kallikrein-related peptidase-8 (KLK8) is an active serine protease in human epidermis and sweat and is involved in a skin barrier proteolytic cascade. J. Biol. Chem. 286, 687-706.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 687-706
-
-
Eissa, A.1
Amodeo, V.2
Smith, C.R.3
Diamandis, E.P.4
-
13
-
-
20144389752
-
Enzymatic profiling of human kallikrein 14 using phage-display substrate technology
-
DOI 10.1515/BC.2005.035
-
Felber, L.M., Borgoño, C.A., Cloutier, S.M., Kündig, C., Kishi, T., Ribeiro Chagas, J., Jichlinski, P., Gygi, C.M., Leisinger, H.J., Diamandis, E.P., et al. (2005). Enzymatic profiling of human kallikrein 14 using phage-display substrate technology. Biol. Chem. 386, 291-298. (Pubitemid 40485435)
-
(2005)
Biological Chemistry
, vol.386
, Issue.3
, pp. 291-298
-
-
Felber, L.M.1
Borgono, C.A.2
Cloutier, S.M.3
Kundig, C.4
Kishi, T.5
Chagas, J.R.6
Jichlinski, P.7
Gygi, C.M.8
Leisinger, H.-J.9
Diamandis, E.P.10
Deperthes, D.11
-
14
-
-
78751608564
-
PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin
-
Frateschi, S., Camerer, E., Crisante, G., Rieser, S., Membrez, M., Charles, R.P., Beermann, F., Stehle, J.C., Breiden, B., Sandhoff, K., et al. (2011). PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin. Nat. Commun. 2, 161.
-
(2011)
Nat. Commun.
, vol.2
, pp. 161
-
-
Frateschi, S.1
Camerer, E.2
Crisante, G.3
Rieser, S.4
Membrez, M.5
Charles, R.P.6
Beermann, F.7
Stehle, J.C.8
Breiden, B.9
Sandhoff, K.10
-
15
-
-
72149106806
-
A novel signaling pathway of tissue kallikrein in promoting keratinocyte migration: Activation of proteinase-activated receptor 1 and epidermal growth factor receptor
-
Epub 2009 Oct 30.
-
Gao, L., Chao, L., Chao, J. (2010a) A novel signaling pathway of tissue kallikrein in promoting keratinocyte migration: activation of proteinase-activated receptor 1 and epidermal growth factor receptor. Exp. Cell. Res. 316, 376-389. Epub 2009 Oct 30.
-
(2010)
Exp. Cell. Res.
, vol.316
, pp. 376-389
-
-
Gao, L.1
Chao, L.2
Chao, J.3
-
16
-
-
77954572813
-
Tissue kallikrein promotes prostate cancer cell migration and invasion via a protease-activated receptor-1-dependent signaling pathway
-
Epub 2009 Oct 30. Gao, L., Smith, R.S., Chen, L.M., Chai, K.X., Chao, L., Chao, J. (2010b) Tissue kallikrein promotes prostate cancer cell migration and invasion via a protease-activated receptor-1-dependent signaling pathway. Biol. Chem. 391, 803-812.
-
(2010)
Biol. Chem.
, vol.391
, pp. 803-812
-
-
Gao, L.1
Smith, R.S.2
Chen, L.M.3
Chai, K.X.4
Chao, L.5
Chao, J.6
-
17
-
-
78149358426
-
Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs
-
Goettig, P., Magdolen, V., and Brandstetter, H. (2010). Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs). Biochimie 92, 1546-1567.
-
(2010)
Biochimie
, vol.92
, pp. 1546-1567
-
-
Goettig, P.1
Magdolen, V.2
Brandstetter, H.3
-
18
-
-
61449179021
-
Aberrant expression of proteinase-activated receptor 4 promotes colon cancer cell proliferation through a persistent signaling that involves Src and ErbB-2 kinase
-
Gratio, V., Walker, F., Lehy, T., Laburthe, M., and Darmoul, D. (2009). Aberrant expression of proteinase-activated receptor 4 promotes colon cancer cell proliferation through a persistent signaling that involves Src and ErbB-2 kinase. Int. J. Cancer 124, 1517-1525.
-
(2009)
Int. J. Cancer
, vol.124
, pp. 1517-1525
-
-
Gratio, V.1
Walker, F.2
Lehy, T.3
Laburthe, M.4
Darmoul, D.5
-
19
-
-
77749245859
-
Kallikrein-related peptidase 4: A new activator of the aberrantly expressed protease-activated receptor 1 in colon cancer cells
-
Gratio, V., Beaufort, N., Seiz, L., Maier, J., Virca, G.D., Debela, M., Grebenchtchikov, N., Magdolen, V., and Darmoul, D. (2010). Kallikrein-related peptidase 4: a new activator of the aberrantly expressed protease-activated receptor 1 in colon cancer cells. Am. J. Pathol. 176, 1452-1461.
-
(2010)
Am. J. Pathol.
, vol.176
, pp. 1452-1461
-
-
Gratio, V.1
Beaufort, N.2
Seiz, L.3
Maier, J.4
Virca, G.D.5
Debela, M.6
Grebenchtchikov, N.7
Magdolen, V.8
Darmoul, D.9
-
20
-
-
80055003183
-
Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signaling pathway in colon cancer cells
-
Sep 9. [Epub ahead of print]
-
Gratio, V., Loriot, C., Virca, G.D., Oikonomopoulou, K., Walker, F., Diamandis, E.P., Hollenberg, M.D., and Darmoul, D. (2011). Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signaling pathway in colon cancer cells. Am. J. Pathol. Sep 9. [Epub ahead of print].
-
(2011)
Am. J. Pathol.
-
-
Gratio, V.1
Loriot, C.2
Virca, G.D.3
Oikonomopoulou, K.4
Walker, F.5
Diamandis, E.P.6
Hollenberg, M.D.7
Darmoul, D.8
-
21
-
-
78751498756
-
Functional selectivity and biased receptor signaling
-
Kenakin, T. (2011). Functional selectivity and biased receptor signaling. J. Pharmacol. Exp. Ther. 336, 296-302.
-
(2011)
J. Pharmacol. Exp. Ther.
, vol.336
, pp. 296-302
-
-
Kenakin, T.1
-
22
-
-
77952354490
-
Seven transmembrane receptors as shapeshifting proteins: The impact of allosteric modulation and functional selectivity on new drug discovery
-
Kenakin, T. and Miller, L.J. (2010). Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery. Pharmacol. Rev. 62, 265-304.
-
(2010)
Pharmacol. Rev.
, vol.62
, pp. 265-304
-
-
Kenakin, T.1
Miller, L.J.2
-
23
-
-
77951298043
-
Prostate-specific antigen screening: Pro
-
Loeb, S. and Catalona, W.J. (2010). Prostate-specific antigen screening: pro. Curr. Opin. Urol. 20, 185-188.
-
(2010)
Curr. Opin. Urol.
, vol.20
, pp. 185-188
-
-
Loeb, S.1
Catalona, W.J.2
-
24
-
-
15444346942
-
Interactions of mast cell tryptase with thrombin receptors and PAR-2
-
DOI 10.1074/jbc.272.7.4043
-
Molino, M., Barnathan, E.S., Numerof, R., Clark, J., Dreyer, M., Cumashi, A., Hoxie, J.A., Schechter, N., Woolkalis, M., and Brass, L.F. (1997a). Interactions of mast cell tryptase with thrombin receptors and PAR-2. J. Biol. Chem. 272, 4043-4049. (Pubitemid 27078466)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.7
, pp. 4043-4049
-
-
Molino, M.1
Barnathan, E.S.2
Numerof, R.3
Clark, J.4
Dreyer, M.5
Cumashi, A.6
Hoxie, J.A.7
Schechter, N.8
Woolkalis, M.9
Brass, L.F.10
-
25
-
-
0030947907
-
Endothelial cell thrombin receptors and PAR-2. Two protease-activated receptors located in a single cellular environment
-
DOI 10.1074/jbc.272.17.11133
-
Molino, M., Woolkalis, M.J., Reavey-Cantwell, J., Pratico, D., Andrade-Gordon, P., Barnathan, E.S., and Brass, L.F. (1997b). Endothelial cell thrombin receptors and PAR-2. Two proteaseactivated receptors located in a single cellular environment. J. Biol. Chem. 272, 11133-11141. (Pubitemid 27184106)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.17
, pp. 11133-11141
-
-
Molino, M.1
Woolkalis, M.J.2
Reavey-Cantwell, J.3
Pratico, D.4
Andrade-Gordon, P.5
Barnathan, E.S.6
Brass, L.F.7
-
26
-
-
33845955449
-
Proteinase-activated receptors, targets for kallikrein signaling
-
DOI 10.1074/jbc.M513138200
-
Oikonomopoulou, K., Hansen, K.K., Saifeddine, M., Tea, I., Blaber, M., Blaber, S.I., Scarisbrick, I., Andrade-Gordon. P., Cottrell, G.S., Bunnett, N.W., et al. (2006a). Proteinase-activated receptors, targets for kallikrein signaling. J. Biol. Chem. 281, 32095-32112. (Pubitemid 46036764)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.43
, pp. 32095-32112
-
-
Oikonomopoulou, K.1
Hansen, K.K.2
Saifeddine, M.3
Tea, I.4
Blaber, M.5
Blaber, S.I.6
Scarisbrick, I.7
Andrade-Gordon, P.8
Cottrell, G.S.9
Bunnett, N.W.10
Diamandis, E.P.11
Hollenberg, M.D.12
-
27
-
-
33745673593
-
Proteinase-mediated cell signalling: Targeting proteinase-activated receptors (PARs) by kallikreins and more
-
DOI 10.1515/BC.2006.086, PII B3876677
-
Oikonomopoulou, K., Hansen, K.K., Saifeddine, M., Vergnolle, N., Tea, I., Diamandis, E.P., and Hollenberg, M.D. (2006b). Proteinase-mediated cell signalling: targeting proteinaseactivated receptors (PARs) by kallikreins and more. Biol. Chem. 387, 677-685. (Pubitemid 43964789)
-
(2006)
Biological Chemistry
, vol.387
, Issue.6
, pp. 677-685
-
-
Oikonomopoulou, K.1
Hansen, K.K.2
Saifeddine, M.3
Vergnolle, N.4
Tea, I.5
Diamandis, E.P.6
Hollenberg, M.D.7
-
28
-
-
77951439498
-
Kallikrein-related peptidases: Proteolysis and signaling in cancer, the new frontier
-
Oikonomopoulou, K., Diamandis, E.P., and Hollenberg, M.D. (2010). Kallikrein-related peptidases: proteolysis and signaling in cancer, the new frontier. Biol. Chem. 391, 299-310.
-
(2010)
Biol. Chem.
, vol.391
, pp. 299-310
-
-
Oikonomopoulou, K.1
Diamandis, E.P.2
Hollenberg, M.D.3
-
29
-
-
70349324342
-
Agonist-biased signaling via proteinase activated receptor-2: Differential activation of calcium and mitogen-activated protein kinase pathways
-
Ramachandran, R., Mihara, K., Mathur, M., Rochdi, M.D., Bouvier, M., Defea, K., and Hollenberg, M.D. (2009). Agonist-biased signaling via proteinase activated receptor-2: differential activation of calcium and mitogen-activated protein kinase pathways. Mol. Pharmacol. 76, 791-801.
-
(2009)
Mol. Pharmacol.
, vol.76
, pp. 791-801
-
-
Ramachandran, R.1
Mihara, K.2
Mathur, M.3
Rochdi, M.D.4
Bouvier, M.5
Defea, K.6
Hollenberg, M.D.7
-
30
-
-
79960114650
-
Neutrophil elastase acts as a biased agonist for proteinaseactivated receptor-2 (PAR2)
-
Ramachandran, R., Mihara, K., Chung, H., Renaux, B., Lau, C.S., Muruve, D.A., DeFea, K.A., Bouvier, M., and Hollenberg, M.D. (2011). Neutrophil elastase acts as a biased agonist for proteinaseactivated receptor-2 (PAR2). J. Biol. Chem. 286, 24638-24648.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 24638-24648
-
-
Ramachandran, R.1
Mihara, K.2
Chung, H.3
Renaux, B.4
Lau, C.S.5
Muruve, D.A.6
Defea, K.A.7
Bouvier, M.8
Hollenberg, M.D.9
-
31
-
-
45549086117
-
Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression
-
Ramsay, A.J., Dong, Y., Hunt, M.L., Linn, M., Samaratunga, H., Clements, J.A., Hooper, J.D. (2008) Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression. J. Biol. Chem. 283, 12293-12304.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 12293-12304
-
-
Ramsay, A.J.1
Dong, Y.2
Hunt, M.L.3
Linn, M.4
Samaratunga, H.5
Clements, J.A.6
Hooper, J.D.7
-
32
-
-
0014056205
-
The insulin-like action of pepsin and pepsinogen
-
Rieser, P. (1967). The insulin-like action of pepsin and pepsinogen. Acta Endocrinol. (Copenh) 54, 375-379.
-
(1967)
Acta Endocrinol. (Copenh)
, vol.54
, pp. 375-379
-
-
Rieser, P.1
-
33
-
-
0013587817
-
Anabolic responses of diaphragm muscle to insulin and to other pancreatic proteins
-
Rieser, P. and Rieser, C.H. (1964). Anabolic responses of diaphragm muscle to insulin and to other pancreatic proteins. Proc. Soc. Exp. Biol. Med. 116, 669-671.
-
(1964)
Proc. Soc. Exp. Biol. Med.
, vol.116
, pp. 669-671
-
-
Rieser, P.1
Rieser, C.H.2
-
34
-
-
37049029404
-
Activation of proteinase-activated receptor-2 by human kallikrein-related peptidases
-
DOI 10.1038/sj.jid.5700965, PII 5700965
-
Stefansson, K., Brattsand, M., Roosterman, D., Kempkes, C., Bocheva, G., Steinhoff, M., and Egelrud, T. (2008). Activation of proteinase-activated receptor-2 by human kallikrein-related peptidases. J. Invest. Dermatol. 128, 18-25. (Pubitemid 350249381)
-
(2008)
Journal of Investigative Dermatology
, vol.128
, Issue.1
, pp. 18-25
-
-
Stefansson, K.1
Brattsand, M.2
Roosterman, D.3
Kempkes, C.4
Bocheva, G.5
Steinhoff, M.6
Egelrud, T.7
-
35
-
-
53749092612
-
Protease-activated receptor dependent and independent signaling by kallikreins 1 and 6 in CNS neuron and astroglial cell lines
-
Vandell, A.G., Larson, N., Laxmikanthan, G., Panos, M., Blaber, S.I., Blaber, M., and Scarisbrick, I.A. (2008). Protease-activated receptor dependent and independent signaling by kallikreins 1 and 6 in CNS neuron and astroglial cell lines. J. Neurochem. 107, 855-870.
-
(2008)
J. Neurochem.
, vol.107
, pp. 855-870
-
-
Vandell, A.G.1
Larson, N.2
Laxmikanthan, G.3
Panos, M.4
Blaber, S.I.5
Blaber, M.6
Scarisbrick, I.A.7
|