Efficacy of vincristine administered via convection-enhanced delivery in a rodent brainstem tumor model documented by bioluminescence imaging

Child's Nervous System

Volumn 28, Issue 4, 2012, Pages 565-574

  Xi, Guifa ^a,d   Rajaram, Veena ^b   Mania Farnell, Babara ^c   Mayanil, Chandra S ^d   Soares, Marcelo B ^e   Tomita, Tadanori ^a   Goldman, Stewart ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b CHILDREN'S MEMORIAL HOSPITAL   (United States)

^c PURDUE UNIVERSITY CALUMET   (United States)

^d CHILDREN S MEMORIAL RESEARCH CENTER   (United States)

^e NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Bioluminescence; Brainstem tumor; Convection enhanced delivery; Rodent model; Vincristine

Indexed keywords

VINCRISTINE SULFATE;

ANIMAL CELL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLUMINESCENCE; BRAIN STEM TUMOR; CONTROLLED STUDY; DRUG EFFICACY; HISTOPATHOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; RAT; TUMOR GROWTH; TUMOR VOLUME;

ANIMALS; BRAIN STEM NEOPLASMS; CONVECTION; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; LUMINESCENT MEASUREMENTS; MALE; RATS; RATS, INBRED F344; RODENTIA; TREATMENT OUTCOME; VINCRISTINE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84859855434     PISSN: 02567040     EISSN: 14330350     Source Type: Journal    
DOI: 10.1007/s00381-012-1690-3     Document Type: Article

References (55)

1. Hargrave D, Bartels U, Bouffet E (2006) Diffuse brainstem glioma in children: critical review of clinical trials. Lancet Oncol 7:241-248 (Pubitemid 43286454)
2. Jallo GI, Penno M, Sukay L, Liu JY, Tyler B, Lee J, Carson BS, Guarnieri M (2005) Experimental models of brainstem tumors: development of a neonatal rat model. Childs Nerv Syst 21:399-403 (Pubitemid 41372163)
3. Recinos PF, Sciubba DM, Jallo GI (2007) Brainstem tumors: where are we today? Pediatr Neurosurg 43:192-201 (Pubitemid 46558914)
4. Kondo A, Goldman S, Vanin EF, Sredni ST, Rajaram V, Soares MB, Tomita T (2009) An experiment brainstem tumor model using in vivo bioluminescence imaging in rat. Childs Nerv Syst 25:527-533
5. Tange Y, Kondo A, Egorin MJ, Mania-Farnell B, Daneriallis GM, Nakazaki H, Sredni ST, Rajaram V, Goldman S, Soares MB, Tomita T (2009) Interstitial continuous infusion therapy in a malignant glioma model in rats. Childs Nerv Syst 25:655-662
6. Debinski W, Tatter SB (2009) Convection-enhanced delivery for the treatment of brain tumors. Expert Rev Neurother 9:1519-1527
7. Ashley DM, Riffkin CD, Lovric MM, Mikeska T, Dobrovic A, Maxwell JA, Friedman HS, Drummond KJ, Kaye AH, Gan HK, Johns TG, Hawkins CJ (2008) In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and/or chemotherapy drugs. Br J Cancer 99:294-304
8. Tagscherer KE, Fassl A, Campos B, Farhadi M, Kraemer A, Böck BC, Macher-Goeppinger S, Radlwimmer B, Wiestler OD, Herold-Mende C, Roth W (2008) Apoptosis-based treatment of glioblastoma with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins. Oncogene 27:6646-6656
9. González PP, Serrano PA, Franco ME, Montes LE, Gomez AF, Campos T (2007) Vincristine-induced acute neurotoxicity versus Guillain-Barré syndrome: a diagnostic dilemma. Eur J Neurol 14:826-828
10. Kai K, Sahto H, Yoshida M, Suzuki T, Shikanai Y, Kajimura T, Furuhama K (2006) Species and sex differences in susceptibility to olfactory lesions among the mouse, rat and monkey following an intravenous injection of vincristine sulphate. Toxicol Pathol 34:223-231
11. Oliver AS, Firth G, McKeran RO (1985) Studies on the intracerebral injection of vincristine free and entrapped within liposomes in the rats. J Neurol Sci 65:25-30 (Pubitemid 15075625)
12. Kazukiko O, Yoshihiko Y, Takafumi T, Saito A, Kakinohana Y, Iraha S, Sugimoto K, Tsuchida Y, Tamaki W, Adachi G, Hyodo A, Murayama S (2006) Hyperfractionated radiotherapy and multi-agent chemotherapy (procarbazine, ACNU and vincristine) for high-grade gliomas: a prospective study. Anticancer Res 26:2457-2462 (Pubitemid 43980217)
13. Masaaki Y, Mitsutoshi I, Masani N, Hitoshi T, Kazuki N, Takeo F (2005) Efficacy and feasibility of procarbazine, ranimustine and vincristine chemotherapy, and the role of surgical resection in anaplastic oligodendroglioma. Anticancer Res 25:3751-3724
14. Barth RF, Kaur B (2009) Rat brain tumor models in experimental neuro-oncology: the C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 gliomas. J Neurooncol 94:299-312
15. Hashizume R, Ozawa T, Dinca EB, Banerjee A, Prados MD, James CD, Gupta N (2010) A human brainstem glioma xenograft model enable for bioluminescene imaging. J Neurooncol 96:151-159
16. Tao-Cheng JH, Gallant EP, Brightman WM, Dosemeci A, Reese TS (2007) Structural changes at synapses after delayed perfusion fixation in different regions of the mouse brain. J Comp Neurol 501:731-740
17. Sorensen AG, Patel S, Harmath C, Bridges S, Synnott J, Sievers A, Yoon YH, Lee EJ, Yang MC, Lewis RF, Harris GJ, Lev M, Schaefer PW, Buchbinder BR, Barest G, Yamada K, Ponzo J, Kwon HY, Gemmete J, Farkas J, Tievsky AL, Ziegler RB, Salhus MR, Weisskoff R (2001) Comparison of diameter and perimeter methods for tumor volume calculation. J Clin Oncol 19:551-557 (Pubitemid 32112870)
18. Dickinson PJ, LeCouteur RA, Higgins RJ, Bringas JR, Larson RF, Yamashita Y, Krauze MT, Forsayeth J, Noble CO, Drummond DC, Kirpotin DB, Park JW, Berger MS, Bankiewicz KS (2010) Canine spontaneous glioma: a translational model system for convection-enhanced delivery. Neuro Oncol 12:928-940
19. Watts RG, Merchant RE (1992) Cerebrovascular effects and tumor kinetics after a single intratumoral injection of human recombinant interkeukin-2 alone or in combination with intravenous chemotherapy in a rat model of glioma. Neurosurgery 31:89-98
20. Redgate ES, Deutsch M, Boggs SS (1991) Time of death of CNS tumor bearing rats can be reliably predicted by body weight-loss patterns. Lab Anim Sci 41:269-273
21. West CG, Gattamaneni R, Blair V (1995) Radiotherapy in the treatment of low-grade astrocytomas. I. A survival analysis. Childs Nerv Syst 11:438-442
22. Woo SY, Donaldson SS, Cox RS (1988) Astrocytoma in children: 14 years' experience at Stanford University Medical Center. J Clin Oncol 6:1001-1007
23. Bryant MJ, Chuah TL, Luff J, Lavin MF, Walker DG (2008) A novel rat model for glioblastoma multiforme using a bioluminescent F98 cell line. J Clin Neurosci 15:545-551
24. Camphausen K, Purow B, Sproull M, Scott T, Ozawa T, Deen DF, Tofilon PJ (2005) Orthotopic growth of human glioma cells quantitatively and qualitatively influences radiation-induced changes in gene expression. Cancer Res 65:10389-10393 (Pubitemid 41743732)
25. Dinca E, Sarkaria J, Schroeder MA, Carlson BL, Voicu R, Gupta N, Berger MS, James CD (2007) Bioluminescence monitoring of intracranial glioblastoma xenograft response to primary and salvage temozolomide therapy. J Neurosurg 107:610-616 (Pubitemid 47451046)
26. Sarkaria JN, Carlson BL, Schroeder MA, Grogan P, Brown PD, Giannini C, Ballman KV, Kitange GJ, Guha A, Pandita A, James CD (2006) Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response. Clin Cancer Res 12:2264-2271
27. Jost SC, Collins L, Traver S, Piwnica-Worms D, Garbow JR (2009) Measuring brain tumor growth: combined bioluminescence imaging-magnetic resonance imaging strategy. Mol Imaging 8:245-253
28. Szentirmai O, Baker CH, Lin N, Szucs S, Takahashi M, Kiryu S, Kung AL, Mulligan RC, Carter BS (2006) Noninvasive bioluminescence imaging of luciferase expressing intracranial U87 xenografts: correlation with magnetic resonance imaging determined tumor volume and longitudinal use in assessing tumor growth and antiangiogenic treatment effect. Neurosurgery 58:365-372 (Pubitemid 43212802)
29. Zhou H, Luby PK, Michey BE, Habib AA, Mason RP, Zhao D (2009) Dynamic near-infrared optical imaging of 2-deoxyglucose uptake by intracranial glioma of athymic mice. PLoS One 4:e8051
30. Kondo A, Goldman S, Lulla RR, Mania-Farnell B, Vanin EF, Sredni ST, Rajaram V, Soares MB, Tomita T (2009) Longitudinal assessment of regional directed delivery in a rodent malignant glioma model. J Neurosurg Pediatr 4:592-598
31. Xi G, Mania-Farnell B, Rajaram V, Mayanil CS, Soares MB, Tomita T, Goldman S (2012) Efficacy of interstitial continuous vincristine infusion in a bioluminescent rodent intracranial tumor model. J Neurooncol 106:261-270
32. Kawabata S, Yang W, Barth RF, Wu G, Huo T, Binns PJ, Riley KJ, Ongayi O, Gottumukkala V, Vicente MG (2011) Convection enhanced delivery of carboranylporphyrins for neutron capture therapy of brain tumors. J Neurooncol 103:175-185
33. Kikuchi T, Saito R, Sugiyama S, Yamashita Y, Kumabe T, Krauze M, Bankiewicz K, Tominaga T (2008) Convection-enhanced delivery of polyethylene glycol-coated liposomal doxorubicin: characterization and efficacy in rat intracranial glioma models. J Neurosurg 109:867-873
34. Mardor Y, Rahav O, Zauberman Y, Lidar Z, Ocherashvilli A, Daniels D, Roth Y, Maier SE, Orenstein A, Ram Z (2005) Convection-Enhanced drug delivery: increased efficacy and magnetic resonance image monitoring. Cancer Res 65:6858-6863 (Pubitemid 41065083)
35. Song DK, Lonser RR (2008) Convection-enhanced delivery for the treatment of pediatric neurologic disorders. J Child Neurol 23:1231-1237
36. Hadjipanayis CG, Machaidze R, Wang L, Schuette AJ, Chen H, Wu X, Mao H (2010) EGFRvIII antibody-conjugated iron oxide nanoparticles for magnetic resonance imaging-guided convection-enhanced delivery and targeted therapy of glioblastoma. Cancer Res 70:6303-6312
37. Kawakami K (2004) Distribution kinetics of targeted cytotoxin in glioma by bolus or convection-enhanced delivery in a murine model. J Neurosurg 101:1004-1011
38. Oh S, Tasi AK, Ohlfest JR, Panoskalesis-Mortari A, Vallera DA (2011) Evaluation of a bispecific biological drug designed to simultaneously target glioblastoma and its neovasculature in the brain. J Neurosurg 114:1662-1671
39. Weber F, Asher A, Bucholz R, Berger M, Prados M, Chang S, Bruce J, HallW, Rainov NG,WestphalM,Warnick RE, Rand RW, Floeth F, Rommel F, Pan H, Hingorani VN, Puri RK (2003) Safty, tolerability, and tumor response of IL4-4 pseudomonas exotoxin (NBI-3001) in patients with recurrent malignant glioma. J Neurooncol 64:125-137 (Pubitemid 36992467)
40. Lun X, Alain T, Zemp FJ, Zhou H, Rahman MM, Hamilton MG, McFadden G, Bell J, Senger DL, Forsyth PA (2010) Myxoma virus virotherapy for glioma in immunocompetent animal models: optimizing administration routes and synergy with rapamycin. Cancer Res 70:598-608
41. Yokosawa M, Sonoda Y, Sugiyama S, Saito R, Yamashita Y, Nishihara M, Satoh T, Kumabe T, Yokoyama M, Tominaga T (2010) Convection-enhanced delivery of a synthetic retinoid Am80, loaded into polymeric micelles, prolongs the survival of rats bearing intracranial glioblastoma xenografts. Tohoku J Exp Med 221:257-264
42. Yang W, Huo T, Barth RF, Gupta N, Weldon M, Grecula JC, Ross BD, Hoff BA, Chou TC, Rousseau J, Elleaume H (2011) Convection enhanced delivery of carboplatin in combination with radiotherapy for the treatment of brain tumors. J Neurooncol 101:379-390
43. Ding D, Kanaly CW, Bigner DD, Cummings TJ, Herndon JE, Pastan I, Raghavan R, Sampson JH (2010) Convection-enhanced delivery of free gadolinium with the recombinant immunotoxin MR1-1. J Neurooncol 98:1-7
44. Sampson JH, Brady M, Raghavan R, Mehta AI, Friedman AH, Reardon DA, Petry NA, Barboriak DP, Wong TZ, Zalutsky MR, Lally-Goss D, Bigner DD (2011) Co-localization of gadolinium-DTPA with high molecular weight molecules after intracerebral convection-enhanced delivery in man. Neurosurgery 69:668-676
45. Bobo RH, Laske DW, Akbasak A, Morrison PF, Dedrick RL, Oldfield EH (1994) Convection-enhanced delivery of macromoleculars in the brain. Proc Natl Acad Sci USA 91:2076-2080
46. Shahar T, Ram Z, Kanner AA (2011) Convection-enhanced delivery catheter placements for high-grade gliomas: complications and pitfalls. J Neurooncol. doi:10.1007/s11060-011-0751-x
47. Sampson JH, Archer G, Pedain C, Wembacher-Schröder E, Westphal M, Kunwar S, Vogelbaum MA, Coan A, Herndon JE, Raghavan R, Brady ML, Reardon DA, Friedman AH, Friedman HS, Rodríguez-Ponce MI, Chang SM, Mittermeyer S, Croteau D, Puri RK, PRECISE Trial Investigators (2010) Poor drug distribution as a possible explanation for the results of the PRECISE trial. J Neurosurg 113:301-309
48. Sampson JH, Brady ML, Petry NA, Croteau D, Friedman AH, Friedman HS, Wong T, Bigner DD, Pastan I, Puri RK, Pedain C (2007) Intracerebral infusate distribution by convection-enhanced delivery in humans with malignant gliomas: descriptive effects of target anatomy and catheter positioning. Neurosurgery 60:89-99
49. Debinski W, Tatter SB (2009) Convection-enhanced delivery for the treatment of brain tumors. Expert Rev Neurother 9:1519-1527
50. Tanner PG, Holtmannspotter M, Tonn JC, Goldbrunner R (2007) Effects of drug efflux on convection-enhanced paclitaxel delivery to malignant gliomas: technical note. Neurosurgery 61:880-882
51. Messinger Y, Gaynon P, Raetz E, Hutchinson R, Dubois S, Glade-Bender J, Sposto R, van der Giessen J, Eckroth E, Bostrom BC (2010) Phase I study of bortezomib combined with chemotherapy in children with relapsed childhood acute lymphoblastic leukemia (ALL): a report from the therapeutic advances in childhood leukemia (TACL) consortium. Pediatr Blood Cancer 55:254-259
52. Phillips AA, Shapira I,Willim RD, Sanmugarajah J, Solomon WB, Horwitz SM, Savage DG, Bhagat G, Soff G, Zain JM, Alobeid B, Seshan VE, O'Connor OA (2010) A critical analysis of prognostic factors in North American patients with human T-cell lymphotropic virus type-1-assocated adult T-cell leukemia/lymphoma: a multicancer clinicopathologic experience and new prognostic score. Cancer 116:3438-3446
53. Spagnuolo PA, Hu J, Hurren R, Wang X, Gronda M, Sukhai MA, Di Meo A, Boss J, Ashali I, Beheshti Zavareh R, Fine N, Simpson CD, Sharmeen S, Rottapel R, Schimmer AD (2010) The antihelmintic flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma. Blood 115:4824-4833
54. Shinwari Z, Manogaran PS, Alrokayan SA, AI-Hussein KA, Aboussekhra A (2008) VCR and lomustine induce apoptosis and P21(WAF1) up-regulation in medulloblastoma and normal human epithelial and fibroblast cells. J Neuroonco 57:123-132
55. Wang F, Zhou F, Kruh GD, Gallo JM (2010) Influence of blood-brain barrier and efflux pumps on the distribution of VCR in brain and brain tumors. Neuro Oncol 12:1043-1049