Brainstem tumors: Where are we today?

Pediatric Neurosurgery

Volumn 43, Issue 3, 2007, Pages 192-201

  Recinos, Pablo F ^a   Sciubba, Daniel M ^a   Jallo, George I ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Brainstem tumors; Cervicomedullary tumors; Dorsal exophytic tumors; Glioma; Medulla; Midbrain tumors; Pontine glioma; Tectal tumors

Indexed keywords

ALPHA INTERFERON; ANGIOSTATIN; ANTINEOPLASTIC AGENT; CORTICOSTEROID; ENDOSTATIN; GANCICLOVIR; POLYMER; PRODRUG; RADIOSENSITIZING AGENT; THYMIDINE KINASE;

BIODEGRADABILITY; BRAIN MAPPING; BRAIN STEM TUMOR; BRAIN SURGERY; CANCER CHEMOTHERAPY; CANCER GENE THERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CRANIOTOMY; DRUG DELIVERY SYSTEM; GLIOMA; HERPES SIMPLEX VIRUS; HUMAN; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PEROPERATIVE ECHOGRAPHY; PRIORITY JOURNAL; REVIEW; SURGICAL APPROACH; TUMOR BIOPSY; TUMOR CLASSIFICATION; TUMOR DIAGNOSIS;

BRAIN STEM; BRAIN STEM NEOPLASMS; CHILD; GLIOMA; HUMANS; MAGNETIC RESONANCE IMAGING; PROGNOSIS; SURVIVAL RATE;

EID: 34147123114     PISSN: 10162291     EISSN: None     Source Type: Journal    
DOI: 10.1159/000098831     Document Type: Review

References (71)

1. Walker DA, Punt JA, Sokal M: Clinical management of brainstem glioma. Arch Dis Child 1999;80:558-564.
2. Allen J: Brain stem glioma. Neurol Neurosurg Update Series 1983, pp 2-7.
3. Littman P, Jarrett P, Bilaniuk LT, Rorke LB, Zimmerman RA, Bruce DA, Carabell SC, Schut L: Pediatric brain stem gliomas. Cancer 1980;45:2787-2792.
4. Berger MS, Edwards MS, LaMasters D, Davis RL, Wilson CB: Pediatric brain stem tumors: radiographic, pathological, and clinical correlations. Neurosurgery 1983;12:298-302.
5. Epstein F, Wisoff JH: Intrinsic brainstem tumors in childhood: surgical indications. J Neurooncol 1988;6:309-317.
6. Albright AL, Pollack IF: Brainstem gliomas; in Winn HR (ed): Youmans Neurological Surgery. Philadelphia, Saunders, 2004, vol 3, pp 3663-3669.
7. Matson D: Tumors of the posterior fossa;in Thomas C (ed): Neurosurgery of Infancy and Childhood. Springfield, Thomas, 1969, pp 469-477.
8. Gilday D, Ash J: Accuracy of brain scanning in pediatric craniocerebral neoplasms. Radiology 1975;117:93-97.
9. Hoffman HJ, Becker L, Craven MA: A clinically and pathologically distinct group of benign brain stem gliomas. Neurosurgery 1980;7:243-248.
10. Stroink AR, Hoffman HJ, Hendrick EB, Humphreys RP, Davidson G: Transependymal benign dorsally exophytic brain stem gliomas in childhood: diagnosis and treatment recommendations. Neurosurgery 1987;20:439-444.
11. Alvisi C, Cerisoli M, Maccheroni ME: Longterm results of surgically treated brainstem gliomas. Acta Neurochir (Wien) 1985;76:12-17.
12. Epstein F, McCleary EL: Intrinsic brainstem tumors of childhood: surgical indications. J Neurosurg 1986;64:11-15.
13. Epstein F: A staging system for brain stem gliomas. Cancer 1985;56:1804-1806.
14. Barkovich AJ, Krischer J, Kun LE, Packer R, Zimmerman RA, Freeman CR, Wara WM, Albright L, Allen JC, Hoffman HJ: Brain stem gliomas: a classification system based on magnetic resonance imaging. Pediatr Neurosurg 1990;16:73-83.
15. Fischbein NJ, Prados MD, Wara W, Russo C, Edwards MS, Barkovich AJ: Radiologic classification of brain stem tumors: correlation of magnetic resonance imaging appearance with clinical outcome. Pediatr Neurosurg 1996;24:9-23.
16. Albright AL: Brain stem gliomas;in J Y (ed): Neurological Surgery. Philadelphia, Saunders, 1996, pp 2603-2611.
17. Choux M, Lena G, Do L: Brainstem tumors; in Choux M, Di Rocco C, Hockley A (eds): Pediatric Neurosurgery. New York, Churchill Livingstone, 2000, pp 471-491.
18. Jallo GI, Biser-Rohrbaugh A, Freed D: Brainstem gliomas. Childs Nerv Syst 2004;20:143-153.
19. Abbott R: Tumors of the medulla. Neurosurg Clin N Am 1993;4:519-527.
20. Albright AL, Guthkelch AN, Packer RJ, Price RA, Rourke LB: Prognostic factors in pediatric brain-stem gliomas. J Neurosurg 1986;65:751-755.
21. Fisher PG, Breiter SN, Carson BS, Wharam MD, Williams JA, Weingart JD, Foer DR, Goldthwaite PT, Tihan T, Burger PC: A clinicopathologic reappraisal of brain stem tumor classification. Identification of pilocystic astrocytoma and fibrillary astrocytoma as distinct entities. Cancer 2000;89:1569-1576.
22. Epstein FJ, Farmer JP: Brain-stem glioma growth patterns. J Neurosurg 1993;78:408-412.
23. Steck J, Friedman WA: Stereotactic biopsy of brainstem mass lesions. Surg Neurol 1995;43:563-567.
24. Rajshekhar V, Chandy MJ: Computerized tomography-guided stereotactic surgery for brainstem masses: a risk-benefit analysis in 71 patients. J Neurosurg 1995;82:976-981.
25. Albright AL, Price RA, Guthkelch AN: Brain stem gliomas of children. A clinicopathological study. Cancer 1983;52:2313-2319.
26. Amundson EW, McGirt MJ, Olivi A: A contralateral, transfrontal, extraventricular approach to stereotactic brainstem biopsy procedures. Technical note. J Neurosurg 2005;102:565-570.
27. Kaplan AM, Albright AL, Zimmerman RA, Rorke LB, Li H, Boyett JM, Finlay JL, Wara WM, Packer RJ: Brainstem gliomas in children. A Children's Cancer Group review of 119 cases. Pediatr Neurosurg 1996;24:185-192.
28. Tomita T, McLone DG, Naidich TP: Brain stem gliomas in childhood. Rational approach and treatment. J Neurooncol 1984;2:117-122.
29. Epstein F: Intrinsic brain stem tumors of childhood. Surgical indications. Prog Exp Tumor Res 1987;30:160-169.
30. Mandell LR, Kadota R, Freeman C, Douglass EC, Fontanesi J, Cohen ME, Kovnar E, Burger P, Sanford RA, Kepner J, Friedman H, Kun LE: There is no role for hyperfractionated radiotherapy in the management of children with newly diagnosed diffuse intrinsic brainstem tumors: results of a Pediatric Oncology Group phase III trial comparing conventional vs. hyperfractionated radiotherapy. Int J Radiat Oncol Biol Phys 1999;43:959-964.
31. Bricolo A: Surgical management of intrinsic brain stem gliomas. Oper Tech Neurosurg 2000;3:137-154.
32. Morota N, Deletis V: The importance of brainstem mapping in brainstem surgical anatomy before the fourth ventricle and implication for intraoperative neurophysiological mapping. Acta Neurochir (Wien) 2006;148:499-509.
33. Morota N, Deletis V, Lee M, Epstein FJ: Functional anatomic relationship between brain-stem tumors and cranial motor nuclei. Neurosurgery 1996;39:787-793
34. Morota N, Deletis V, Epstein FJ, Kofler M, Abbott R, Lee M, Ruskin K: Brain stem mapping: neurophysiological localization of motor nuclei on the floor of the fourth ventricle. Neurosurgery 1995;37:922-929.
35. Sala F, Krzan MJ, Deletis V: Intraoperative neurophysiological monitoring in pediatric neurosurgery: why, when, how? Childs Nerv Syst 2002;18:264-287.
36. Li KW, Roonprapunt C, Lawson HC, Abbott IR, Wisoff J, Epstein F, Jallo GI: Endoscopic third ventriculostomy for hydrocephalus associated with tectal gliomas. Neurosurg Focus 2005;18:E2.
37. Stark AM, Fritsch MJ, Claviez A, Dorner L, Mehdorn HM: Management of tectal glioma in childhood. Pediatr Neurol 2005;33:33-38.
38. Pollack IF, Polinko P, Albright AL, Towbin R, Fitz C: Mutism and pseudobulbar symptoms after resection of posterior fossa tumors in children: incidence and pathophysiology. Neurosurgery 1995;37:885-893.
39. Steinbok P, Cochrane DD, Perrin R, Price A: Mutism after posterior fossa tumour resection in children: incomplete recovery on long-term follow-up. Pediatr Neurosurg 2003;39:179-183.
40. Wisoff JH, Epstein FJ: Pseudobulbar palsy after posterior fossa operation in children. Neurosurgery 1984;15:707-709.
41. Jallo GI, Kothbauer KF, Epstein FJ: Surgical management of cervicomedullary and dorsally exophytic brain stem tumors. Oper Tech Neurosurg 2000;3:131-136.
42. Pollack IF, Hoffman HJ, Humphreys RP, Becker L: The long-term outcome after surgical treatment of dorsally exophytic brainstem gliomas. J Neurosurg 1993;78:859-863.
43. Abbott R, Shiminski-Maher T, Epstein FJ: Intrinsic tumors of the medulla: predicting outcome after surgery. Pediatr Neurosurg 1996;25:41-44.
44. Abbott R, Shiminski-Maher T, Wisoff JH, Epstein FJ: Intrinsic tumors of the medulla: surgical complications. Pediatr Neurosurg 1991;17:239-244.
45. Shiminski-Maher T: Brainstem tumors in childhood: preparing patients and families for long- and short-term care. Pediatr Neurosurg 1996;24:267-271.
46. Jallo GI, Shiminski-Maher T, Velazquez L, Abbott R, Wisoff J, Epstein F: Recovery of lower cranial nerve function after surgery for medullary brainstem tumors. Neurosurgery 2005;56:74-77.
47. Shiminski-Maher T, Abbott R, Wisoff JH, Epstein FJ: Current trends in the management of brainstem tumors in childhood. J Neurosci Nurs 1991;23:356-362.
48. Epstein F, Wisoff J: Intra-axial tumors of the cervicomedullary junction. J Neurosurg 1987;67:483-487.
49. Weiner HL, Freed D, Woo HH, Rezai AR, Kim R, Epstein FJ: Intra-axial tumors of the cervicomedullary junction: surgical results and long-term outcome. Pediatr Neurosurg 1997;27:12-18.
50. Gomez-Gosalvez FA, Menor F, Morant A, Clemente F, Escriva P, Carbonell J, Mulas F: Tectal tumours in paediatrics. A review of eight patients (in Spanish). Rev Neurol 2001;33:605-611.
51. Bowers DC, Georgiades C, Aronson LJ, Carson BS, Weingart JD, Wharam MD, Melhem ER, Burger PC, Cohen KJ: Tectal gliomas: natural history of an indolent lesion in pediatric patients. Pediatr Neurosurg 2000;32:24-29.
52. Packer RJ, Boyett JM, Zimmerman RA, Albright AL, Kaplan AM, Rorke LB, Selch MT, Cherlow JM, Finlay JL, Wara WM: Outcome of children with brain stem gliomas after treatment with 7800 cGy of hyperfractionated radiotherapy. A Childrens Cancer Group Phase I/II Trial. Cancer 1994;74:1827-1834.
53. Khatib ZA, Heideman RL, Kovnar EH, Langston JA, Sanford RA, Douglas EC, Ochs J, Jenkins JJ, Fairclough DL, Greenwald C, et al: Predominance of pilocytic histology in dorsally exophytic brain stem tumors. Pediatr Neurosurg 1994;20:2-10.
54. Robertson PL, Allen JC, Abbott IR, Miller DC, Fidel J, Epstein FJ: Cervicomedullary tumors in children: a distinct subset of brainstem gliomas. Neurology 1994;44:1798-1803.
55. Albright AL: Diffuse brainstem tumors: when is a biopsy necessary? Pediatr Neurosurg 1996;24:252-255.
56. Albright AL: Tumors of the pons. Neurosurg Clin N Am 1993;4:529-536.
57. Allen JC, Siffert J: Contemporary chemotherapy issues for children with brainstem gliomas. Pediatr Neurosurg 1996;24:98-102.
58. Jallo GI, Penno M, Sukay L, Liu JY, Tyler B, Lee J, Carson BS, Guarnieri M: Experimental models of brainstem tumors: development of a neonatal rat model. Childs Nerv Syst 2005;21:399-403.
59. Lee J, Jallo GI, Guarnieri M, Carson BS Sr, Penno MB: A novel brainstem tumor model: guide screw technology with functional, radiological, and histopathological characterization. Neurosurg Focus 2005;18:E11.
60. Brem H, Tamargo RJ, Olivi A, Pinn M, Weingart JD, Wharam M, Epstein JI: Biodegradable polymers for controlled delivery of chemotherapy with and without radiation therapy in the monkey brain. J Neurosurg 1994;80:283-290.
61. Bobo RH, Laske DW, Akbasak A, Morrison PF, Dedrick RL, Oldfield EH: Convection-enhanced delivery of macromolecules in the brain. Proc Natl Acad Sci USA 1994;91:2076-2080.
62. 14C-sucrose delivery to the brain by intravenous, intraventricular, and convection-enhanced intracerebral infusion. J Neurosurg 1999;90:321-331.
63. Occhiogrosso G, Edgar MA, Sandberg DI, Souweidane MM: Prolonged convection-enhanced delivery into the rat brainstem. Neurosurgery 2003;52:388-393;discussion 393-384.
64. Miura F, Moriuchi S, Maeda M, Sano A, Maruno M, Tsanaclis AM, Marino R Jr, Glorioso JC, Yoshimine T: Sustained release of low-dose ganciclovir from a silicone formulation prolonged the survival of rats with gliosarcomas under herpes simplex virus thymidine kinase suicide gene therapy. Gene Ther 2002;9:1653-1658.
65. Burrows FJ, Gore M, Smiley WR, Kanemitsu MY, Jolly DJ, Read SB, Nicholas T, Kruse CA: Purified herpes simplex virus thymidine kinase retroviral particles. III. Characterization of bystander killing mechanisms in transfected tumor cells. Cancer Gene Ther 2002;9:87-95.
66. Todo T, Rabkin SD, Martuza RL: Evaluation of ganciclovir-mediated enhancement of the antitumoral effect in oncolytic, multimutated herpes simplex virus type 1 (G207) therapy of brain tumors. Cancer Gene Ther 2000;7:939-946.
67. De Bouard S, Guillamo JS, Christov C, Lefevre N, Brugieres P, Gola E, Devanz P, Indraccolo S, Peschanski M: Antiangiogenic therapy against experimental glioblastoma using genetically engineered cells producing interferon-alpha, angiostatin, or endostatin. Hum Gene Ther 2003;14:883-895.
68. Ruan S, Okcu MF, Pong RC, Andreeff M, Levin V, Hsieh JT, Zhang W: Attenuation of WAF1/Cip1 expression by an antisense adenovirus expression vector sensitizes glioblastoma cells to apoptosis induced by chemotherapeutic agents 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin. Clin Cancer Res 1999;5:197-202.
69. Miller CR, Williams CR, Buchsbaum DJ, Gillespie GY: Intratumoral 5-fluorouracil produced by cytosine deaminase/5-fluorocytosine gene therapy is effective for experimental human glioblastomas. Cancer Res 2002;62:773-780.
70. Yamanaka R, Yajima N, Tsuchiya N, Honma J, Tanaka R, Ramsey J, Blaese M, Xanthopoulos KG: Administration of interleukin-12 and -18 enhancing the antitumor immunity of genetically modified dendritic cells that had been pulsed with Semliki forest virus-mediated tumor complementary DNA. J Neurosurg 2002;97:1184-1190.
71. Rand V, Huang J, Stockwell T, Ferriera S, Buzko O, Levy S, Busam D, Li K, Edwards JB, Eberhart C, Murphy KM, Tsiamouri A, Beeson K, Simpson AJ, Venter JC, Riggins GJ, Strausberg RL: Sequence survey of receptor tyrosine kinases reveals mutations in glioblastomas. Proc Natl Acad Sci USA 2005;102:14344-14349.