Seasonal leptin resistance is associated with impaired signalling via JAK2-STAT3 but not ERK, possibly mediated by reduced hypothalamic GRB2 protein

Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology

Volumn 182, Issue 4, 2012, Pages 553-567

  Tups, Alexander ^c   Stöhr, Sigrid ^c   Helwig, Michael ^b   Barrett, Perry ^a   Krol, Elzbieta ^d   Schachtner, Joachim ^c   Mercer, Julian G ^a   Klingenspor, Martin ^e  

^a ROWETT RESEARCH INSTITUTE   (United Kingdom)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d UNIVERSITY OF ABERDEEN   (United Kingdom)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Arcuate nucleus; Body weight regulation; Leptin receptor; Suppressor of cytokine signalling

Indexed keywords

GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; ISOPROTEIN; JANUS KINASE 2; LEPTIN; LEPTIN RECEPTOR; MESSENGER RNA; NERVE PROTEIN; PROTEIN TYROSINE PHOSPHATASE SHP 2; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL; ARTICLE; CELL NUCLEUS; CYTOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HAMSTER; HYPOTHALAMUS; MALE; METABOLISM; NERVE CELL; PHODOPUS; PHOTOPERIODICITY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANIMALS; CELL NUCLEUS; CRICETINAE; FEMALE; GENE EXPRESSION REGULATION; GRB2 ADAPTOR PROTEIN; HYPOTHALAMUS; JANUS KINASE 2; LEPTIN; MALE; NERVE TISSUE PROTEINS; NEURONS; PHODOPUS; PHOTOPERIOD; PROTEIN ISOFORMS; PROTEIN TRANSPORT; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; RECEPTORS, LEPTIN; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

CRICETINAE; PHODOPUS SUNGORUS; RODENTIA;

EID: 84859849212     PISSN: 01741578     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00360-011-0637-4     Document Type: Article

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