Mitochondrial molecular basis of sevoflurane and propofol cardioprotection in patients undergoing aortic valve replacement with cardiopulmonary bypass

Cellular Physiology and Biochemistry

Volumn 29, Issue 1-2, 2012, Pages 131-142

  Jovic, Miomir ^a   Stancic, Ana ^a   Nenadic, Dragan ^a   Cekic, Olivera ^a   Nezic, Dusko ^a   Milojevic, Predrag ^a   Micovic, Slobodan ^a   Buzadzic, Biljana ^a   Korac, Aleksandra ^a   Otasevic, Vesna ^a   Jankovic, Aleksandra ^a   Vucetic, Milica ^a   Velickovic, Ksenija ^a   Golic, Igor ^a   Korac, Bato ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Cardioprotection; Ischemia reperfusion; Mitochondria; Propofol; Sevoflurane

Indexed keywords

BRAIN NATRIURETIC PEPTIDE; CONNEXIN 43; CYTOCHROME C OXIDASE; MESSENGER RNA; MITOCHONDRIAL DNA; PROPOFOL; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SEVOFLURANE; SUFENTANIL; TROPONIN I; UNCOUPLING PROTEIN 2;

ADULT; ANESTHESIA INDUCTION; AORTA VALVE REPLACEMENT; AORTA VALVE STENOSIS; ARTICLE; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CONFOCAL MICROSCOPY; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FEMALE; HEART MITOCHONDRION; HEART PROTECTION; HEMODYNAMICS; HUMAN; IMMUNOCYTOCHEMISTRY; IMMUNOGOLD LABELING; IMMUNOHISTOCHEMISTRY; LENGTH OF STAY; MALE; PRIORITY JOURNAL; PROTEIN DETERMINATION; RANDOMIZED CONTROLLED TRIAL; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 84859848948     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000337594     Document Type: Article

References (43)

1. De Hert SG, Van der Linden PJ, Cromheecke S, Meeus R, Nelis A, Van Reeth V, ten Broecke PW, De Blier IG, Stockman BA, Rodrigus IE: Cardioprotective properties of sevoflurane in patients undergoing coronary surgery with cardiopulmonary bypass are related to the modalities of its administration. Anesthesiology 2004;101:299-310. (Pubitemid 38988484)
2. Javadov SA, Lim KH, Kerr PM, Suleiman MS, Angelini GD, Halestrap AP: Protection of hearts from reperfusion injury by propofol is associated with inhibition of the mitochondrial permeability transition. Cardiovasc Res 2000;45:360-369. (Pubitemid 30069501)
3. Xia Z, Huang Z, Ansley DM: Large-dose propofol during cardiopulmonary bypass decreases biochemical markers of myocardial injury in coronary surgery patients: a comparison with isoflurane. Anesth Analg 2006;103:527-532. (Pubitemid 44542898)
4. De Hert SG, ten Broecke PW, Mertens E, Van Sommeren EW, De Blier IG, Stockman BA, Rodrigus IE: Sevoflurane but not propofol preserves myocardial function in coronary surgery patients. Anesthesiology 2002;97:42-49. (Pubitemid 34733920)
5. Conzen PF, Fischer S, Detter C, Peter K: Sevoflurane provides greater protection of the myocardium than propofol in patients undergoing off-pump coronary artery bypass surgery. Anesthesiology 2003;99:826-833. (Pubitemid 37186071)
6. Guarracino F, Landoni G, Tritapepe L, Pompei F, Leoni A, Aletti G, Scandroglio AM, Maselli D, De Luca M, Marchetti C, Crescenzi G, Zangrillo A: Myocardial damage prevented by volatile anesthetics: a multicenter randomized controlled study. J Cardiothorac Vasc Anesth 2006;20:477-483. (Pubitemid 44119282)
7. Tritapepe L, Landoni G, Guarracino F, Pompei F, Crivellari M, Maselli D, De Luca M, Fochi O, D'Avolio S, Bignami E, Calabrò MG, Zangrillo A: Cardiac protection by volatile anaesthetics: a multicentre randomized controlled study in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass. Eur J Anaesthesiol 2007;24:323-331.
8. Julier K, da Silva R, Garcia C, Bestmann L, Frascarolo P, Zollinger A, Chassot PG, Schmid ER, Turina MI, von Segesser LK, Pasch T, Spahn DR, Zaugg M: Preconditioning by sevoflurane decreases biochemical markers for myocardial and renal dysfunction in coronary artery bypass graft surgery: a double-blinded, placebo-controlled, multicenter study. Anesthesiology 2003;98:1315-1327. (Pubitemid 36622462)
9. Jakobsen CJ, Berg H, Hindsholm KB, Faddy N, Sloth E: The influence of propofol versus sevoflurane anesthesia on outcome in 10,535 cardiac surgical procedures. J Cardiothorac Vasc Anesth 2007;21:664-671. (Pubitemid 47464955)
10. Hirata N, Kanaya N, Kamada N, Kimura S, Namiki A: Differential effects of propofol and sevoflurane on ischemiainduced ventricular arrhythmias and phosphorylated connexin 43 protein in rats. Anesthesiology 2009;110:50-57.
11. Kersten JR, Schmeling TJ, Pagel PS, Gross GJ, Warltier DC: Isoflurane mimics ischemic preconditioning via activation of K(ATP) channels: reduction of myocardial infarct size with an acute memory phase. Anesthesiology 1997;87:361-370. (Pubitemid 27435379)
12. Novalija E, Fujita S, Kampine JP, Stowe DF: Sevoflurane mimics ischemic preconditioning effects on coronary flow and nitric oxide release in isolated hearts. Anesthesiology 1999;91:701-712. (Pubitemid 29418652)
13. Novalija E, Varadarajan SG, Camara AK, An J, Chen Q, Riess ML, Hogg N, Stowe DF: Anesthetic preconditioning: triggering role of reactive oxygen and nitrogen species in isolated hearts. Am J Physiol Heart Circ Physiol 2002;283:44-52.
14. Müllenheim J, Ebel D, Frässdorf J, Preckel B, Thämer V, Schlack W: Isoflurane preconditions myocardium against infarction via release of free radicals. Anesthesiology 2002;96:934-940. (Pubitemid 34266688)
15. Yabe K, Nasa Y, Sato M, Iijima R, Takeo S: Preconditioning preserves mitochondrial function and glycolytic flux during an early period of reperfusion in perfused rat hearts. Cardiovasc Res 1997;33:677-685. (Pubitemid 27092870)
16. Crestanello JA, Doliba NM, Babsky AM, Doliba NM, Niibori K, Whitman GJ, Osbakken MD: Ischemic preconditioning improves mitochondrial tolerance to experimental calcium overload. J Surg Res 2002;103:243-251. (Pubitemid 34948508)
17. Novalija E, Kevin LG, Eells JT, Henry MM, Stowe DF: Anesthetic preconditioning improves adenosine triphosphate synthesis and reduces reactive oxygen species formation in mitochondria after ischemia by a redox dependent mechanism. Anesthesiology 2003;98:1155-1163. (Pubitemid 36520202)
18. Vasilijevic A, Vojcic Lj, Dinulovic I, Buzadzic B, Korac A, Petrovic V, Jankovic A, Korac B: Expression pattern of thermogenesis-related factors in interscapular brown adipose tissue of alloxan-treated rats: beneficial effect of L-arginine. Nitric Oxide 2010;23:42-50.
19. Petrovic V, Korac A, Buzadzic B, Korac B: The effects of L-arginine and LNAME supplementation on redoxregulation and thermogenesis in interscapular brown adipose tissue. J Exp Biol 2005;208:4263-4271. (Pubitemid 41789752)
20. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-275.
21. Toller WG, Kersten JR, Pagel PS, Hettrick DA, Warltier DC: Sevoflurane reduces myocardial infarct size and decreases the time threshold for ischemic preconditioning in dogs. Anesthesiology 1999;91:1437-1446. (Pubitemid 29506108)
22. de Ruijter W, Musters RJ, Boer C, Stienen GJ, Simonides WS, de Lange JJ: The cardioprotective effect of sevoflurane depends on protein kinase C activation, opening of mitochondrial K+ ATP channels, and the production of reactive oxygen species. Anesth Analg 2003;97:1370-1376. (Pubitemid 37310136)
23. Ko SH, Yu CW, Lee SK, Choe H, Chung MJ, Kwak YG, Chae SW, Song HS: Propofol attenuates ischemiareperfusion injury in the isolated rat heart. Anesth Analg 1997;85:719-724. (Pubitemid 27418869)
24. Kokita N, Hara A, Abiko Y, Arakawa J, Hashizume H, Namiki A: Propofol improves functional and metabolic recovery in ischemic reperfused isolated rat hearts. Anesth Analg 1998;86:252-258. (Pubitemid 28079471)
25. Li Volti G, Murabito P, Attaguille G, Rodella LF, Astuto M, Di Giacomo C, Gullo A: Antioxidant properties of propofol: when oxidative stress sleeps with patients. EXCLI Journal 2006;5:25-32.
26. Wickley PJ, Ding X, Murray PA, Damron DS: Propofol-induced activation of rotein kinase C isoforms in adult rat ventricular myocytes. Anesthesiology 2006;104:970-977.
27. Kamada N, Kanaya N, Hirata N, Kimura S, Namiki A: Cardioprotective effects of propofol in isolated ischemia-reperfused guinea pig hearts: role of KATP channels and GSK-3beta. Can J Anaesth 2008;55:595-605.
28. Sun H, Xue F, Xu Y, Li C, Xiong J, Liao X, Zhang Y: Propofol improves cardiac functional recovery after ischemiareperfusion by upregulating nitric oxide synthase activity in the isolated rat hearts. Chin Med J 2009;122:3048-3054.
29. Czerski LW, Szweda PA, Szweda LI: Dissociation of cytochrome c from the inner mitochondrial membrane during cardiac ischemia. J Biol Chem 2003;278:34499-34504. (Pubitemid 37553298)
30. Dhein S, Polontchouk L, Salameh A, Haefliger JA: Pharmacological modulation and differential regulation of the cardiac gap junction proteins connexin 43 and connexin 40. Biol Cell 2002;94:409-422. (Pubitemid 36113693)
31. Boengler K, Dodoni G, Rodriguez-Sinovas A, Cabestrero A, Ruiz-Meana M, Gres P, Konietzka I, Lopez-Iglesias C, Garcia-Dorado D, Di Lisa F, Heusch G, Schulz R: Connexin 43 in cardiomyocyte mitochondria and its increase by ischemic preconditioning. Cardiovasc Res 2005;67:234-244. (Pubitemid 40943616)
32. Heinzel FR, Luo Y, Li X, Boengler K, Buechert A, Garcïa-Dorado D, Di Lisa F, Schulz R, Heusch G: Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice. Circ Res 2005;97:583-586. (Pubitemid 41361749)
33. Goubaeva F, Mikami M, Giardina S, Ding B, Abe J, Yang J: Cardiac mitochondrial connexin 43 regulates apoptosis. Biochem Biophys Res Commun 2007;352:97-103. (Pubitemid 44821099)
34. Corral-Debrinski M, Shoffner JM, Lott MT, Wallace DC: Association of mitochondrial DNA damage with aging and coronary atherosclerotic heart disease. Mutat Res 1992;275:169-180.
35. Ide T, Tsutsui H, Hayashidani S, Kang D, Suematsu S, Nakamura K, Utsumi H, Hamasaki N, Takeshita, A: Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts following myocardial infarction. Circ Res 2001;88:529-535. (Pubitemid 32240917)
36. Lee HC, Wei YH: Mitochondrial role in life and death of the cell. J Biomed Sci 2000;7:2-15.
37. Barrientos A, Casademont J, Cardellach F, Ardite E, Estivill X, Urbano-Márquez A, Fernández-Checa JC, Nunes V: Qualitative and quantitative changes in skeletal muscle mtDNA and expression of mitochondrial-encoded genes in the human aging process. Biochem Mol Med 1997;62:165-171. (Pubitemid 28063393)
38. Ames BN, Shigenaga MK, Hagen TM: Mitochondrial decay in aging. Biochim Biophys Acta 1995;1271:165-170.
39. Attardi G, Schatz G: Biogenesis of mitochondria. Annu Rev Cell Biol 1988;4:289-333. (Pubitemid 19139259)
40. Nicholls DG, Locke RM: Thermogenic mechanisms in brown fat. Physiol Rev 1984;64:1-64. (Pubitemid 14139945)
41. Teshima Y, Akao M, Jones SP, Marbán E: Uncoupling protein-2 overexpression inhibits mitochondrial death pathway in cardiomyocytes. Circ Res 2003;93:192-200. (Pubitemid 36993229)
42. McLeod CJ, Aziz A, Hoyt RF Jr, McCoy JP Jr, Sack MN: Uncoupling proteins 2 and 3 function in concert to augment tolerance to cardiac ischemia. J Biol Chem 2005;280:33470-33476. (Pubitemid 41397146)
43. Ljubkovic M, Mio Y, Marinovic J, Stadnicka A, Warltier DC, Bosnjak ZJ, Bienengraeber M: Isoflurane preconditioning uncouples mitochondria and protects against hypoxiareoxygenation. Am J Physiol Cell Physiol 2007;292:1583-1590.