Apoptotic neurodegeneration and spatial memory are not affected by sedative and anaesthetics doses of ketamine/medetomidine combinations in adult mice

British Journal of Anaesthesia

Volumn 108, Issue 5, 2012, Pages 807-814

  Ribeiro, P O ^a,b   Valentim, A M ^a,b   Rodrigues, P ^b   Olsson, I A ^a   Antunes, L M ^a,b  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

Author keywords

Anaesthetics; Apoptosis; Cognition; Ketamine; Medetomidine

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE 3; KETAMINE; MEDETOMIDINE; OXYGEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY TEMPERATURE; BREATHING RATE; CONTROLLED STUDY; DENTATE GYRUS; DRUG SAFETY; ENZYME ACTIVATION; EXPERIMENTAL TEST; HEART RATE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INTRAVENOUS ANESTHESIA; MALE; MAZE TEST; MOUSE; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; OPEN FIELD TEST; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RETROSPLENIAL CORTEX; SEDATION; SPATIAL MEMORY; SYSTOLIC BLOOD PRESSURE; VERTICAL POLE TEST; VISUAL CORTEX;

EID: 84859840810     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aes003     Document Type: Article

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