Design and synthesis of carbamate and thiocarbamate derivatives and their inhibitory activities of NO production in LPS activated macrophages

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 9, 2012, Pages 3301-3304

  Jin, Guo Hua ^a   Lee, Hwa Jin ^a   Gim, Hyo Jin ^a   Ryu, Jae Ha ^a   Jeon, Raok ^a  

^a Sookmyung Women's University   (South Korea)

Author keywords

Carbamate; iNOS; Nitric oxide; Thiocarbamate

Indexed keywords

AMINOGUANIDINE; CARBAMIC ACID; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; SYNAPTOTAGMIN I; THIOCARBAMIC ACID;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; IC 50; MACROPHAGE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

CARBAMATES; HUMANS; INHIBITORY CONCENTRATION 50; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; STRUCTURE-ACTIVITY RELATIONSHIP; THIOCARBAMATES;

EID: 84859831913     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.03.010     Document Type: Article

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