Inhibition of 12-lipoxygenase reduces proliferation and induces apoptosis of hepatocellular carcinoma cells in vitro and in vivo

Hepatobiliary and Pancreatic Diseases International

Volumn 11, Issue 2, 2012, Pages 193-202

  Xu, Xi Ming ^a   Yuan, Guang Jin ^b   Deng, Jun Jian ^a   Guo, Hong Ting ^a   Xiang, Miao ^a   Yang, Fang ^c   Ge, Wei ^a   Chen, Shi You ^d  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b Cancer Center   (China)

^c WUHAN UNIVERSITY   (China)

^d UNIVERSITY OF GEORGIA   (United States)

Author keywords

12 lipoxygenase; Apoptosis; Hepatocellular carcinoma; Proliferation

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ARACHIDONATE 12 LIPOXYGENASE; BAICALEIN; CASPASE 3; DIETHYLNITROSAMINE; GLUTATHIONE TRANSFERASE P1; KI 67 ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOMA CELL; CELL ASSAY; CELL PROLIFERATION; CELL STRAIN HEPG2; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; LIVER NODULE; MALE; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 84859816459     PISSN: 14993872     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1499-3872(12)60147-7     Document Type: Article

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