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Volumn 515, Issue 2, 2012, Pages 125-130

M1 muscarinic acetylcholine receptor interacts with BACE1 and regulates its proteosomal degradation

Author keywords

Amyloid; Site APP cleaving protein 1; Alzheimer's disease; M1 Muscarinic acetylcholine receptor; Proteosomal degradation

Indexed keywords

AMYLOID BETA PROTEIN; BETA SECRETASE 1; MESSENGER RNA; MUSCARINIC RECEPTOR;

EID: 84859770808     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.03.026     Document Type: Article
Times cited : (19)

References (26)
  • 3
    • 64549132538 scopus 로고    scopus 로고
    • M1 agonists as a potential disease-modifying therapy for Alzheimer's disease
    • Caccamo A., Fisher A., LaFerla F.M. M1 agonists as a potential disease-modifying therapy for Alzheimer's disease. Curr. Alzheimer Res. 2009, 6:112-117.
    • (2009) Curr. Alzheimer Res. , vol.6 , pp. 112-117
    • Caccamo, A.1    Fisher, A.2    LaFerla, F.M.3
  • 5
    • 0036932174 scopus 로고    scopus 로고
    • Decreased muscarinic1 receptors in the dorsolateral prefrontal cortex of subjects with schizophrenia
    • Dean B., McLeod M., Keriakous D., McKenzie J., Scarr E. Decreased muscarinic1 receptors in the dorsolateral prefrontal cortex of subjects with schizophrenia. Mol. Psychiatry 2002, 7:1083-1091.
    • (2002) Mol. Psychiatry , vol.7 , pp. 1083-1091
    • Dean, B.1    McLeod, M.2    Keriakous, D.3    McKenzie, J.4    Scarr, E.5
  • 6
    • 37049003111 scopus 로고    scopus 로고
    • M1 muscarinic agonists target major hallmarks of Alzheimer's disease-an update
    • Fisher A. M1 muscarinic agonists target major hallmarks of Alzheimer's disease-an update. Curr. Alzheimer Res. 2007, 4:577-580.
    • (2007) Curr. Alzheimer Res. , vol.4 , pp. 577-580
    • Fisher, A.1
  • 7
    • 0033781487 scopus 로고    scopus 로고
    • Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3beta inhibition and in neurons
    • Forlenza O.V., Spink J.M., Dayanandan R., Anderton B.H., Olesen O.F., Lovestone S. Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3beta inhibition and in neurons. J. Neural Transm. 2000, 107:1201-1212.
    • (2000) J. Neural Transm. , vol.107 , pp. 1201-1212
    • Forlenza, O.V.1    Spink, J.M.2    Dayanandan, R.3    Anderton, B.H.4    Olesen, O.F.5    Lovestone, S.6
  • 8
    • 30744472172 scopus 로고    scopus 로고
    • Suppression of cyclin-dependent kinase 5 activation by amyloid precursor protein: a novel excitoprotective mechanism involving modulation of tau phosphorylation
    • Han P., Dou F., Li F., Zhang X., Zhang Y.W., Zheng H., Lipton S.A., Xu H., Liao F.F. Suppression of cyclin-dependent kinase 5 activation by amyloid precursor protein: a novel excitoprotective mechanism involving modulation of tau phosphorylation. J. Neurosci. 2005, 25:11542-11552.
    • (2005) J. Neurosci. , vol.25 , pp. 11542-11552
    • Han, P.1    Dou, F.2    Li, F.3    Zhang, X.4    Zhang, Y.W.5    Zheng, H.6    Lipton, S.A.7    Xu, H.8    Liao, F.F.9
  • 9
    • 0026597063 scopus 로고
    • Alzheimer's disease: the amyloid cascade hypothesis
    • Hardy J.A., Higgins G.A. Alzheimer's disease: the amyloid cascade hypothesis. Science 1992, 256:184-185.
    • (1992) Science , vol.256 , pp. 184-185
    • Hardy, J.A.1    Higgins, G.A.2
  • 10
    • 0031751761 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase-dependent and protein kinase C-dependent pathways link the M1 muscarinic receptor to beta-amyloid precursor protein secretion
    • Haring R., Fisher A., Marciano D., Pittel Z., Kloog Y., Zuckerman A., Eshhar N., Heldman E. Mitogen-activated protein kinase-dependent and protein kinase C-dependent pathways link the M1 muscarinic receptor to beta-amyloid precursor protein secretion. J. Neurochem. 1998, 71:2094-2103.
    • (1998) J. Neurochem. , vol.71 , pp. 2094-2103
    • Haring, R.1    Fisher, A.2    Marciano, D.3    Pittel, Z.4    Kloog, Y.5    Zuckerman, A.6    Eshhar, N.7    Heldman, E.8
  • 11
    • 4644357534 scopus 로고    scopus 로고
    • Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation
    • He W., Lu Y., Qahwash I., Hu X.Y., Chang A., Yan R. Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation. Nat. Med. 2004, 10:959-965.
    • (2004) Nat. Med. , vol.10 , pp. 959-965
    • He, W.1    Lu, Y.2    Qahwash, I.3    Hu, X.Y.4    Chang, A.5    Yan, R.6
  • 12
    • 15744380393 scopus 로고    scopus 로고
    • GGA proteins mediate the recycling pathway of memapsin 2 (BACE)
    • He X., Li F., Chang W.P., Tang J. GGA proteins mediate the recycling pathway of memapsin 2 (BACE). J. Biol. Chem. 2005, 280:11696-11703.
    • (2005) J. Biol. Chem. , vol.280 , pp. 11696-11703
    • He, X.1    Li, F.2    Chang, W.P.3    Tang, J.4
  • 13
    • 0037013209 scopus 로고    scopus 로고
    • Beta-secretase processing in the trans-Golgi network preferentially generates truncated amyloid species that accumulate in Alzheimer's disease brain
    • Huse J.T., Liu K., Pijak D.S., Carlin D., Lee V.M., Doms R.W. Beta-secretase processing in the trans-Golgi network preferentially generates truncated amyloid species that accumulate in Alzheimer's disease brain. J. Biol. Chem. 2002, 277:16278-16284.
    • (2002) J. Biol. Chem. , vol.277 , pp. 16278-16284
    • Huse, J.T.1    Liu, K.2    Pijak, D.S.3    Carlin, D.4    Lee, V.M.5    Doms, R.W.6
  • 14
    • 0034721842 scopus 로고    scopus 로고
    • Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme. The Alzheimer's disease beta-secretase
    • Huse J.T., Pijak D.S., Leslie G.J., Lee V.M., Doms R.W. Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme. The Alzheimer's disease beta-secretase. J. Biol. Chem. 2000, 275:33729-33737.
    • (2000) J. Biol. Chem. , vol.275 , pp. 33729-33737
    • Huse, J.T.1    Pijak, D.S.2    Leslie, G.J.3    Lee, V.M.4    Doms, R.W.5
  • 15
    • 33745616542 scopus 로고    scopus 로고
    • Meta-analysis shows strong positive association of the neuregulin 1 (NRG1) gene with schizophrenia
    • Li D., Collier D.A., He L. Meta-analysis shows strong positive association of the neuregulin 1 (NRG1) gene with schizophrenia. Hum. Mol. Genet. 2006, 15:1995-2002.
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 1995-2002
    • Li, D.1    Collier, D.A.2    He, L.3
  • 16
    • 0030779677 scopus 로고    scopus 로고
    • Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives
    • Mattson M.P. Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives. Physiol. Rev. 1997, 77:1081-1132.
    • (1997) Physiol. Rev. , vol.77 , pp. 1081-1132
    • Mattson, M.P.1
  • 17
    • 77954115000 scopus 로고    scopus 로고
    • Cognitive effects of muscarinic M1 functional agonists in non-human primates and clinical trials
    • McArthur R.A., Gray J., Schreiber R. Cognitive effects of muscarinic M1 functional agonists in non-human primates and clinical trials. Curr. Opin. Investig. Drugs 2010, 11:740-760.
    • (2010) Curr. Opin. Investig. Drugs , vol.11 , pp. 740-760
    • McArthur, R.A.1    Gray, J.2    Schreiber, R.3
  • 18
    • 33748755837 scopus 로고    scopus 로고
    • Reticulons RTN3 and RTN4-B/C interact with BACE1 and inhibit its ability to produce amyloid beta-protein
    • Murayama K.S., Kametani F., Saito S., Kume H., Akiyama H., Araki W. Reticulons RTN3 and RTN4-B/C interact with BACE1 and inhibit its ability to produce amyloid beta-protein. Eur. J. Neurosci. 2006, 24:1237-1244.
    • (2006) Eur. J. Neurosci. , vol.24 , pp. 1237-1244
    • Murayama, K.S.1    Kametani, F.2    Saito, S.3    Kume, H.4    Akiyama, H.5    Araki, W.6
  • 19
    • 0029670637 scopus 로고    scopus 로고
    • Activation of M1 muscarinic acetylcholine receptor regulates tau phosphorylation in transfected PC12 cells
    • Sadot E., Gurwitz D., Barg J., Behar L., Ginzburg I., Fisher A. Activation of M1 muscarinic acetylcholine receptor regulates tau phosphorylation in transfected PC12 cells. J. Neurochem. 1996, 66:877-880.
    • (1996) J. Neurochem. , vol.66 , pp. 877-880
    • Sadot, E.1    Gurwitz, D.2    Barg, J.3    Behar, L.4    Ginzburg, I.5    Fisher, A.6
  • 24
    • 79955128215 scopus 로고    scopus 로고
    • Biology and pathophysiology of the amyloid precursor protein
    • Zheng H., Koo E.H. Biology and pathophysiology of the amyloid precursor protein. Mol. Neurodegener. 2011, 6:27.
    • (2011) Mol. Neurodegener. , vol.6 , pp. 27
    • Zheng, H.1    Koo, E.H.2
  • 25
  • 26
    • 3042712380 scopus 로고    scopus 로고
    • Beta-secretase BACE1 is differentially controlled through muscarinic acetylcholine receptor signaling
    • Zuchner T., Perez-Polo J.R., Schliebs R. Beta-secretase BACE1 is differentially controlled through muscarinic acetylcholine receptor signaling. J. Neurosci. Res. 2004, 77:250-257.
    • (2004) J. Neurosci. Res. , vol.77 , pp. 250-257
    • Zuchner, T.1    Perez-Polo, J.R.2    Schliebs, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.