Protective role of adiponectin against ethanol-induced gastric injury in mice

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 302, Issue 8, 2012, Pages

  Yamamoto, Shunsuke ^a   Watabe, Kenji ^a   Araki, Hiroshi ^b   Kamada, Yoshihiro ^a   Kato, Motohiko ^a   Kizu, Takashi ^a   Kiso, Shinichi ^a   Tsutsui, Shusaku ^b   Tsujii, Masahiko ^a   Kihara, Shinji ^a   Funahashi, Tohru ^a   Shimomura, Iichiro ^a   Hayashi, Norio ^c   Takehara, Tetsuo ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Itami City Hospital   (Japan)

^c KANSAI ROSAI HOSPITAL   (Japan)

Author keywords

Cyclooxygenase; Prostaglandin

Indexed keywords

ADIPONECTIN; ALCOHOL; CELECOXIB; PROSTAGLANDIN E2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STOMACH INJURY; STOMACH MUCOSA;

ADIPONECTIN; ANIMALS; APOPTOSIS; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CYCLOOXYGENASE 2; DINOPROSTONE; ETHANOL; GASTRIC MUCOSA; HSP70 HEAT-SHOCK PROTEINS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; RATS; REAL-TIME POLYMERASE CHAIN REACTION; STOMACH DISEASES; WOUND HEALING;

EID: 84859770464     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00324.2011     Document Type: Article

References (50)

1. Araki H, Nishihara T, Matsuda M, Fukuhara A, Kihara S, Funahashi T, Kataoka TR, Kamada Y, Kiyohara T, Tamura S, Hayashi N, Shimomura I. Adiponectin plays a protective role in caerulein-induced acute pancreatitis in mice fed a high-fat diet. Gut 57: 1431-1440, 2008.
2. Bhandari P, Bateman AC, Mehta RL, Patel P. Mucosal expression of cyclooxygenase isoforms 1 and 2 is increased with worsening damage to the gastric mucosa. Histopathology 46: 280-286, 2005.
3. Dutta SK, Arora M, Kireet A, Bashandy H, Gandsas A. Upper gastrointestinal symptoms and associated disorders in morbidly obese patients: a prospective study. Dig Dis Sci 54: 1243-1246, 2009.
4. Ehrlich K, Sicking C, Respondek M, Peskar BM. Interaction of cyclo-oxygenase isoenzymes, nitric oxide, and afferent neurons in gastric mucosal defense in rats. J Pharmacol Exp Ther 308: 277-283, 2004.
5. Fu HY, Asahi K, Hayashi Y, Eguchi H, Murata H, Tsujii M, Tsuji S, Azuma T, Kawano S. East Asian-type Helicobacter pylori cytotoxinassociated gene A protein has a more significant effect on growth of rat gastric mucosal cells than the Western type. J Gastroenterol Hepatol 22: 355-362, 2007.
6. Fukata M, Nakagawa M, Kaibuchi K. Roles of Rho-family GTPases in cell polarisation and directional migration. Curr Opin Cell Biol 15: 590-597, 2003.
7. Garrow D, Delegge MH. Risk factors for gastrointestinal ulcer disease in the US population. Dig Dis Sci 55: 66-72, 2010.
8. Gretzer B, Maricic N, Respondek M, Schuligoi R, Peskar BM. Effects of specific inhibition of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the rat stomach with normal mucosa and after acid challenge. Br J Pharmacol 132: 1565-1573, 2001.
9. Hoshino T, Tsutsumi S, Tomisato W, Hwang HJ, Tsuchiya T, Miz-ushima T. Prostaglandin E2 protects gastric mucosal cells from apoptosis via EP2 and EP4 receptor activation. J Biol Chem 278: 12752-12758, 2003.
10. Ikeda Y, Ohashi K, Shibata R, Pimentel DR, Kihara S, Ouchi N, Walsh K. Cyclooxygenase-2 induction by adiponectin is regulated by a sphingosine kinase-1 dependent mechanism in cardiac myocytes. FEBS Lett 582: 1147-1150, 2008.
11. Jones MK, Sasaki E, Halter F, Pai R, Nakamura T, Arakawa T, Kuroki T, Tarnawski AS. HGF triggers activation of the COX-2 gene in rat gastric epithelial cells: action mediated through the ERK2 signaling pathway. FASEB J 13: 2186-2194, 1999.
12. Jones MK, Tomikawa M, Mohajer B, Tarnawski AS. Gastrointestinal mucosal regeneration: role of growth factors. Front Biosci 4: D303-309, 1999.
13. Kadowaki T, Yamauchi T. Adiponectin and adiponectin receptors. Endocr Rev 26: 439-451, 2005.
14. Kamada Y, Tamura S, Kiso S, Matsumoto H, Saji Y, Yoshida Y, Fukui K, Maeda N, Nishizawa H, Nagaretani H, Okamoto Y, Kihara S, Miyagawa J, Shinomura Y, Funahashi T, Matsuzawa Y. Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin. Gastroenterology 125: 1796-1807, 2003.
15. Katsiougiannis S, Tenta R, Skopouli FN. Activation of AMP-activated protein kinase by adiponectin rescues salivary gland epithelial cells from spontaneous and interferon-gamma-induced apoptosis. Arthritis Rheum 62: 414-419, 2010.
16. Kim HJ, Yoo TW, Park DI, Park JH, Cho YK, Sohn CI, Jeon WK, Kim BI. Influence of overweight and obesity on upper endoscopic findings. J Gastroenterol Hepatol 22: 477-481, 2007.
17. Kobayashi I, Kawano S, Tsuji S, Matsui H, Nakama A, Sawaoka H, Masuda E, Takei Y, Nagano K, Fusamoto H, Ohno T, Fukutomi H, Kamada T. RGM1, a cell line derived from normal gastric mucosa of rat. In Vitro Cell Dev Biol Anim 32: 259-261, 1996.
18. Kusunoki N, Kitahara K, Kojima F, Tanaka N, Kaneko K, Endo H, Suguro T, Kawai S. Adiponectin stimulates prostaglandin E(2) production in rheumatoid arthritis synovial fibroblasts. Arthritis Rheum 62: 1641-1649, 2010.
19. Lacy ER, Ito S. Rapid epithelial restitution of the rat gastric mucosa after ethanol injury. Lab Invest 51: 573-583, 1984.
20. Ladwein M, Rottner K. On the Rho'd: the regulation of membrane protrusions by Rho-GTPases. FEBS Lett 582: 2066-2074, 2008.
21. Laine L, Takeuchi K, Tarnawski A. Gastric mucosal defense and cytoprotection: bench to bedside. Gastroenterology 135: 41-60, 2008.
22. Lee HW, Kim SY, Kim AY, Lee EJ, Choi JY, Kim JB. Adiponectin stimulates osteoblast differentiation through induction of COX2 in mesenchymal progenitor cells. Stem Cells 27: 2254-2262, 2009.
23. Maeda K, Okubo K, Shimomura I, Funahashi T, Matsuzawa Y, Matsubara K. cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (adipose most abundant gene transcript 1). Biochem Biophys Res Commun 221: 286-289, 1996.
24. Maeda N, Shimomura I, Kishida K, Nishizawa H, Matsuda M, Nagaretani H, Furuyama N, Kondo H, Takahashi M, Arita Y, Komuro R, Ouchi N, Kihara S, Tochino Y, Okutomi K, Horie M, Takeda S, Aoyama T, Funahashi T, Matsuzawa Y. Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nat Med 8: 731-737, 2002.
25. Maricic N, Ehrlich K, Gretzer B, Schuligoi R, Respondek M, Peskar BM. Selective cyclo-oxygenase-2 inhibitors aggravate ischaemia-reperfusion injury in the rat stomach. Br J Pharmacol 128: 1659-1666, 1999.
26. Martin GR, Wallace JL. Gastrointestinal inflammation: a central component of mucosal defense and repair. Exp Biol Med (Maywood) 231: 130-137, 2006.
27. Matsuzawa Y. Adiponectin: a key player in obesity related disorders. Curr Pharm Des 16: 1896-1901, 2010.
28. Miyake K, Tsukui T, Wada K, Tatsuguchi A, Futagami S, Hiratsuka T, Shinoki K, Iizumi T, Akamatsu T, Sakamoto C, Kobayashi M. Irritant-induced cyclooxygenase-2 is involved in the defense mechanism of the gastric mucosa in mice. J Gastroenterol 37: 164-171, 2002.
29. Mustonen H, Hietaranta A, Puolakkainen P, Kemppainen E, Paimela H, Kiviluoto T, Kivilaakso E. Ethanol induced NFB activation protects against cell injury in cultured rat gastric mucosal epithelium. Am J Physiol Gastrointest Liver Physiol 292: G1614-G1621, 2007.
30. Nakagawa Y, Kishida K, Kihara S, Funahashi T, Shimomura I. Adiponectin ameliorates hypoxia-induced pulmonary arterial remodeling. Biochem Biophys Res Commun 382: 183-188, 2009.
31. Nakamura N, Naruse K, Matsuki T, Hamada Y, Nakashima E, Kamiya H, Matsubara T, Enomoto A, Takahashi M, Oiso Y, Nakamura J. Adiponectin promotes migration activities of endothelial progenitor cells via Cdc42/Rac1. FEBS Lett 583: 2457-2463, 2009.
32. Nishihara T, Matsuda M, Araki H, Oshima K, Kihara S, Funahashi T, Shimomura I. Effect of adiponectin on murine colitis induced by dextran sulfate sodium. Gastroenterology 131: 853-861, 2006.
33. Oates PJ, Hakkinen JP. Studies on the mechanism of ethanol-induced gastric damage in rats. Gastroenterology 94: 10-21, 1988.
34. Ogiyama H, Kamada Y, Kiso S, Araki H, Yamada T, Nishihara T, Watabe K, Tochino Y, Kihara S, Funahashi T, Kanno K, Shimomura I, Tsutsui S, Tazuma S, Hayashi N. Lack of adiponectin promotes formation of cholesterol gallstones in mice. Biochem Biophys Res Commun 399: 352-358, 2010.
35. Okamoto Y, Kihara S, Ouchi N, Nishida M, Arita Y, Kumada M, Ohashi K, Sakai N, Shimomura I, Kobayashi H, Terasaka N, Inaba T, Funahashi T, Matsuzawa Y. Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice. Circulation 106: 2767-2770, 2002.
36. Ouchi N, Kobayashi H, Kihara S, Kumada M, Sato K, Inoue T, Funahashi T, Walsh K. Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells. J Biol Chem 279: 1304-1309, 2004.
37. Ouchi N, Walsh K. Adiponectin as an anti-inflammatory factor. Clin Chim Acta 380: 24-30, 2007.
38. Ouchi N, Walsh K. A novel role for adiponectin in the regulation of inflammation. Arterioscler Thromb Vasc Biol 28: 1219-1221, 2008.
39. Renshaw AA, Rabaza JR, Gonzalez AM, Verdeja JC. Helicobacter pylori infection in patients undergoing gastric bypass surgery for morbid obesity. Obes Surg 11: 281-283, 2001.
40. Rudi J, Kuck D, Strand S, von Herbay A, Mariani SM, Krammer PH, Galle PR, Stremmel W. Involvement of the CD95 (APO-1/Fas) receptor and ligand system in Helicobacter pylori-induced gastric epithelial apoptosis. J Clin Invest 102: 1506-1514, 1998.
41. Sawaoka H, Tsuji S, Tsujii M, Gunawan ES, Nakama A, Takei Y, Nagano K, Matsui H, Kawano S, Hori M. Expression of the cyclooxygenase-2 gene in gastric epithelium. J Clin Gastroenterol 25, Suppl 1: S105-S110, 1997.
42. Schaffler A, Scholmerich J. The role of adiponectin in inflammatory gastrointestinal diseases. Gut 58: 317-322, 2009.
43. Shankar RR, Vikram K, Ananthakrishnan N, Harish BN, Jayanthi S. Erosive gastroduodenitis and Helicobacter pylori infection. Med Sci Monit 9: CR222-CR224, 2003.
44. Shibata R, Sato K, Pimentel DR, Takemura Y, Kihara S, Ohashi K, Funahashi T, Ouchi N, Walsh K. Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK-and COX-2-dependent mechanisms. Nat Med 11: 1096-1103, 2005.
45. Tarnawski A, Hollander D, Stachura J, Krause WJ, Gergely H. Prostaglandin protection of the gastric mucosa against alcohol injury-a dynamic time-related process. Role of the mucosal proliferative zone. Gastroenterology 88: 334-352, 1985.
46. Terano A, Sakata-Horie K, Shimada T, Hiraishi H, Yoshiura K, Yoneda M, Takahashi M, Fujimori T. The role of cellular migration in the repair process of gastric epithelial cells. Life Sci 69: 3083-3089, 2001.
47. Tilg H, Wolf AM. Adiponectin: a key fat-derived molecule regulating inflammation. Expert Opin Ther Targets 9: 245-251, 2005.
48. Wilson DE. Role of prostaglandins in gastroduodenal mucosal protection. J Clin Gastroenterol 13, Suppl 1: S65-S71, 1991.
49. Yamada T, Araki H, Watabe K, Kamada Y, Kiso S, Ogiyama H, Nishihara T, Kihara S, Funahashi T, Shimomura I, Tsutsui S, Hayashi N. Adiponectin deficiency enhanced the severity of ceruleininduced chronic pancreatitis in mice. J Gastroenterol 45: 742-749, 2010.
50. Yamamoto S, Watabe K, Tsutsui S, Kiso S, Hamasaki T, Kato M, Kamada Y, Yoshida Y, Kihara S, Umeda M, Furubayashi A, Kinoshita K, Kishida O, Fujimoto T, Yamada A, Tsukamoto Y, Hayashi N, Matsuzawa Y. Lower serum level of adiponectin is associated with increased risk of endoscopic erosive gastritis. Dig Dis Sci 56: 2354-2360, 2011.