Modulation of immunogenicity and immunoprotection of mucosal vaccine against coxsackievirus B3 by optimizing the coadministration mode of lymphotactin adjuvant

DNA and Cell Biology

Volumn 31, Issue 4, 2012, Pages 479-488

  Yue, Yan ^a   Xu, Wei ^a   Xiong, Sidong ^a  

^a SOOCHOW UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ANTIGEN; CHITOSAN; DNA VACCINE; IMMUNOGLOBULIN G; LYMPHOTACTIN; PROTEIN VP1; VIRUS VACCINE;

ADJUVANT THERAPY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELLULAR IMMUNITY; CISTRON; CLONE; COXSACKIE VIRUS B; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNITY; IMMUNIZATION; IMMUNOGENICITY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOMODULATION; MALE; MOUSE; MYOCARDITIS; NONHUMAN; PRIORITY JOURNAL; VECTOR CONTROL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; BLOTTING, WESTERN; CHITOSAN; COXSACKIEVIRUS INFECTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; ENZYME-LINKED IMMUNOSPOT ASSAY; IMMUNITY, MUCOSAL; KAPLAN-MEIER ESTIMATE; LYMPHOKINES; MALE; MICE; MICE, INBRED BALB C; MYOCARDITIS; PLASMIDS; SIALOGLYCOPROTEINS; T-LYMPHOCYTES; VACCINES, DNA;

COXSACKIEVIRUS; MUS;

EID: 84859756854     PISSN: 10445498     EISSN: 15577430     Source Type: Journal    
DOI: 10.1089/dna.2011.1367     Document Type: Article

References (36)

1. Adamsson, J., Lindblad, M., Lundqvist, A., Kelly, D., Holmgren, J. and Harandi, A.M. (2006). Novel immunostimulatory agent based on CpG oligodeoxynucleotide linked to the nontoxic B subunit of cholera toxin. J Immunol 176, 4902-4913.
2. Calabrese, F., and Thiene, G. (2003). Myocarditis and inflammatory cardiomyopathy: microbiological and molecular biological aspects. Cardiovasc Res 60, 11-25.
3. Cranage, M.P., and Manoussaka, M. (2009). Modern mucosal vaccines, adjuvants and microbicides. Expert Rev Anti Infect Ther 7, 21-23.
4. Duerr A. (2010). Update on mucosal HIV vaccine vectors. Curr Opin HIV AIDS 5, 397-403.
5. Hedrick, J.A., and Zlotnik, A. (1998). Lymphotactin. Clin Immunol Immunopathol 87, 218-222.
6. Hirschhorn-Cymerman, D., and Perales, M.A. (2010). Cytokine-FC fusion genes as molecular adjuvants for DNA vaccines. Methods Mol Biol 651, 131-155.
7. Hokey, D.A., and Misra, A. (2011). Aerosol vaccines for tuberculosis: a fine line between protection and pathology. Tuberculosis 91, 82-85.
8. Hope, M., Riding, G., Menzies, M., and Willadsen, P. (2004). A novel antigen from Anaplasma marginale: characterization, expression and preliminary evaluation of the recombinant protein. Vaccine 22, 407-415.
9. + Tc1 tumor localization and therapy. Gene Ther 12, 999-1010.
10. Huang, Y.S., Chen, Z., Yang, Z.Y., Wang, T.Y., Zhou, L., Wu, J.B., and Zhou, L.F. (2007). Preparation and characterization of a potent, long-lasting recombinant human serum albumininterferon-alpha2b fusion protein expressed in Pichia pastoris. Eur J Pharm Biopharm 67, 301-308.
11. Jeyanathan, M., Heriazon, A., and Xing, Z. (2010). Airway luminal T cells: a newcomer on the stage of TB vaccination strategies. Trends Immunol 31, 247-252.
12. Kim, S.J., Lee, C., Lee, S.Y., Kim, I., Park, J.S., Sasagawa, T., Ko, J.J., Park, S.E., and Oh, Y.K. (2003). Enhanced immunogenicity of human papillomavirus 16 L1 genetic vaccines fused to an ER-targeting secretory signal peptide and RANTES. Gene Ther 10, 1268-1273.
13. Le Guiner, C., Stieger, K., Snyder, R.O., Rolling, F., and Moullier, P. (2007). Immune responses to gene product of inducible promoters. Curr Gene Ther 7, 334-346.
14. Lillard, J.W. Jr., Boyaka, P.N., Hedrick, J.A., Zlotnik, A., and McGhee, J.R. (1999). Lymphotactin acts as an innate mucosal adjuvant. J Immunol 162, 1959-1965.
15. Lin, C.C., Yu, Y.L., Shih, C.C., Liu, K.J., Ou, K.L., Hong, L.Z., Chen, J.D., and Chu, C.L. (2011). A novel adjuvant Ling Zhi-8 enhances the efficacy of DNA cancer vaccine by activating dendritic cells. Cancer Immunol Immunother 60, 1019-1027.
16. Luo, H., Wong, J., and Wong, B. (2010). Protein degradation systems in viral myocarditis leading to dilated cardiomyopathy. Cardiovasc Res 85, 347-356.
17. Marinaro, M., Fasano, A., and De Magistris, M.T. (2003). Zonula occludens toxin acts as an adjuvant through different mucosal routes and induces protective immune responses. Infect Immun 71, 1897-1902.
18. Middel, P., Thelen, P., Blaschke, S., Polzien, F., Reich, K., Blaschke, V., Wrede, A., Hummel, K.M., Gunawan, B., and Radzun, H.J. (2001). Expression of the T-cell chemoattractant chemokine lymphotactin in Crohn's disease. Am J Pathol 159, 1751-1761.
19. Mishra, P.J., Menon, L.G., Mayer-Kuckuk, P., Bertino, J.R., and Banerjee, D. (2009). Translational modulation of proteins expressed from bicistronic vectors. Mol Imaging 8, 305-318.
20. Moreira, L.O., Smith, A.M., DeFreitas, A.A., Qualls, J.E., El Kasmi, K.C., and Murray, P.J. (2008). Modulation of adaptive immunity by different adjuvant-antigen combinations in mice lacking Nod2. Vaccine 26, 5808-5813.
21. Prego, C., Paolicelli, P., Diaz, B., Vicente, S., Sanchez, A., Gonzalez-Fernandez, A., and Alonso, M.J. (2010). Chitosan-based nanoparticles for improving immunization against hepatitis B infection. Vaccine 28, 2607-2614.
22. Salyaev, R.K., Rigano, M.M., and Rekoslavskaya, N.I. (2010). Development of plant-based mucosal vaccines against widespread infectious diseases. Expert Rev Vaccines 9, 937-946.
23. Singh, M., Ott, G., Kazzaz, J., Ugozzoli, M., Briones, M., Donnelly, J., and O'Hagan, D.T. (2001). Cationic microparticles are an effective delivery system for immune stimulatory cpG DNA. Pharm Res 18, 1476-1479.
24. Takahashi, I., Nochi, T., Yuki, Y., and Kiyono, H. (2009). New horizon of mucosal immunity and vaccines. Curr Opin Immunol 21, 352-358.
25. Tang, M., Wang, H., Zhou, S., and Tian, G. (2008). Enhancement of the immunogenicity of an infectious bronchitis virus DNA vaccine by a bicistronic plasmid encoding nucleocapsid protein and interleukin-2. J Virol Methods 149, 42-48.
26. Tong,H., Qin, S., Fernandes, J.C., Li, L., Dai, K., and Zhang, X. (2009). Progress and prospects of chitosan and its derivatives as non-viral gene vectors in gene therapy. Curr Gene Ther 9, 495-502.
27. Tudor, D., Derrien, M., Diomede, L., Drillet, A.S., Houimel, M., Moog, C., Reynes, J.M., Lopalco, L., and Bomsel, M. (2009). HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4( + ) cell infection: an IgA gene and functional analysis. Mucosal Immunol 2, 412-426.
28. Tuinstra. R.L., Peterson, F.C., Kutlesa, S., Elgin, E.S., Kron, M.A., and Volkman, B.F. (2008). Interconversion between two unrelated protein folds in the lymphotactin native state. Proc Natl Acad Sci U S A 105, 5057-5062.
29. Vajdy, M., Srivastava, I., Polo, J., Donnelly, J., O'Hagan, D., and Singh, M. (2004). Mucosal adjuvants and delivery systems for protein-, DNA- and RNA-based vaccines. Immunol Cell Biol 82, 617-627.
30. van Drunen Littel-van den Hurk, S., Lawman, Z., Wilson, D., Luxembourg, A., Ellefsen, B., van den Hurk, J.V., and Hannaman, D. (2010). Electroporation enhances immune responses and protection induced by a bovine viral diarrhea virus DNA vaccine in newborn calves with maternal antibodies. Vaccine 28, 6445-6454.
31. Wheatley, A.K., Kramski, M., Alexander, M.R., Toe, J.G., Center, R.J., and Purcell, D.F. (2011). Co-expression of miRNA targeting the expression of PERK, but not PKR, enhances cellular immunity from an HIV-1 Env DNA vaccine. PLoS One 6, e18225.
32. Williman, J., Young, S., Buchan, G., Slobbe, L., Wilson, M., Pang, P., Austyn, J., Preston, S., and Baird, M. (2008). DNA fusion vaccines incorporating IL-23 or RANTES for use in immunization against influenza. Vaccine 26, 5153-5158.
33. Xu, W., Shen, Y., Jiang, Z., Wang, Y., Chu, Y., and Xiong, S. (2004). Intranasal delivery of chitosan-DNA vaccine generates mucosal SIgA and anti-CVB3 protection. Vaccine 22, 3603-3612.
34. Yo, Y.T., Hsu, K.F., Shieh, G.S., Lo, C.W., Chang, C.C., Wu, C.L., and Shiau, A.L. (2007). Coexpression of Flt3 ligand and GMCSF genes modulates immune responses induced by HER2/ neu DNA vaccine. Cancer Gene Ther 14, 904-917.
35. Yue, Y., Xu, W., Hu, L., Jiang, Z., and Xiong, S. (2009). Enhanced resistance to coxsackievirus B3-induced myocarditis by intranasal co-immunization of lymphotactin gene encapsulated in chitosan particle. Virology 386, 438-447.
36. Zhang, J., Zhou, Z., Wang, C., Shen, J., Zheng, Y., Zhang, L., Wang, J., and Xia, D. (2011). Reduced tumorigenesis of EG7 after interleukin-10 gene transfer and enhanced efficacy in combination with intratumorally injection of adenovirusmediated lymphotactin and the underlying mechanism. Cancer Immunol Immunother 60, 559-573.