-
1
-
-
78149478781
-
Aberrant epigenetic landscape incancer: How cellular identity goes awry
-
Berdasco M, Esteller M. (2010). Aberrant epigenetic landscape incancer: how cellular identity goes awry. Dev cell 19: 698-711.
-
(2010)
Dev Cell
, vol.19
, pp. 698-711
-
-
Berdasco, M.1
Esteller, M.2
-
2
-
-
54049084380
-
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymaltransition
-
Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J, ShannonMF et al. (2008). A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymaltransition. Cancer Res 68: 7846-7854.
-
(2008)
Cancer Res
, vol.68
, pp. 7846-7854
-
-
Bracken, C.P.1
Gregory, P.A.2
Kolesnikoff, N.3
Bert, A.G.4
Shannonmf, W.J.5
-
3
-
-
44649163918
-
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
-
DOI 10.1038/embor.2008.74, PII EMBOR200874
-
Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna Set al. (2008). A reciprocal repression between ZEB1 and members ofthe miR-200 family promotes EMT and invasion in cancer cells.EMBO Rep 9: 582-589. (Pubitemid 351772923)
-
(2008)
EMBO Reports
, vol.9
, Issue.6
, pp. 582-589
-
-
Burk, U.1
Schubert, J.2
Wellner, U.3
Schmalhofer, O.4
Vincan, E.5
Spaderna, S.6
Brabletz, T.7
-
4
-
-
34247540446
-
Epigenetics and microRNAs
-
DOI 10.1203/pdr.0b013e3180457684
-
Chuang JC, Jones PA. (2007). Epigenetics and microRNAs. PediatrRes 61: 24R-29R. (Pubitemid 46653064)
-
(2007)
Pediatric Research
, vol.61
, Issue.PART 2 SUPPL.
-
-
Chuang, J.C.1
Jones, P.A.2
-
5
-
-
54449085718
-
Sustained induction of epithelialto mesenchymal transition activates DNA methylation of genessilenced in basal-like breast cancers
-
Dumont N, Wilson MB, Crawford YG, Reynolds PA, Sigaroudinia M, Tlsty TD. (2008). Sustained induction of epithelialto mesenchymal transition activates DNA methylation of genessilenced in basal-like breast cancers. Proc Natl Acad Sci USA 105:14867-14872.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 14867-14872
-
-
Dumont, N.1
Wilson, M.B.2
Crawford, Y.G.3
Reynolds, P.A.4
Sigaroudinia, M.5
Tlsty, T.D.6
-
6
-
-
20144388095
-
DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells
-
DOI 10.1038/sj.onc.1208429
-
Eger A, Aigner K, Sonderegger S, Dampier B, Oehler S, Schreiber Met al. (2005). DeltaEF1 is a transcriptional repressor of E-cadherinand regulates epithelial plasticity in breast cancer cells. Oncogene 24:2375-2385. (Pubitemid 40546696)
-
(2005)
Oncogene
, vol.24
, Issue.14
, pp. 2375-2385
-
-
Eger, A.1
Aigner, K.2
Sonderegger, S.3
Dampier, B.4
Oehler, S.5
Schreiber, M.6
Berx, G.7
Cano, A.8
Beug, H.9
Foisner, R.10
-
7
-
-
77952299722
-
MiR-124 and miR-203 are epigenetically silenced tumorsuppressivemicroRNAs in hepatocellular carcinoma
-
Furuta M, Kozaki K, Tanaka S, Arii S, Imoto I, Inazawa J.(2009). miR-124 and miR-203 are epigenetically silenced tumorsuppressivemicroRNAs in hepatocellular carcinoma. Carcinogenesis31: 766-776.
-
(2009)
Carcinogenesis
, vol.31
, pp. 766-776
-
-
Furuta, M.1
Kozaki, K.2
Tanaka, S.3
Arii, S.4
Imoto, I.5
Inazawa, J.6
-
8
-
-
0033959520
-
Cancerstatistics, 2000
-
Greenlee RT, Murray T, Bolden S, Wingo PA. (2000). Cancerstatistics, 2000. CA Cancer J Clin 50: 7-33.
-
(2000)
CA Cancer J Clin
, vol.50
, pp. 7-33
-
-
Greenlee, R.T.1
Murray, T.2
Bolden, S.3
Wingo, P.A.4
-
9
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
DOI 10.1038/ncb1722, PII NCB1722
-
Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid Get al. (2008). The miR-200 family and miR-205 regulate epithelial tomesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol10: 593-601. (Pubitemid 351627379)
-
(2008)
Nature Cell Biology
, vol.10
, Issue.5
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
Barry, S.C.4
Tsykin, A.5
Farshid, G.6
Vadas, M.A.7
Khew-Goodall, Y.8
Goodall, G.J.9
-
10
-
-
29744431723
-
Promoter methylation and inactivation of tumour-suppressor genes in oral squamous-cell carcinoma
-
DOI 10.1016/S1470-2045(05)70540-4, PII S1470204505705404
-
Ha PK, Califano JA. (2006). Promoter methylation and inactivation oftumour-suppressor genes in oral squamous-cell carcinoma. LancetOncol 7: 77-82. (Pubitemid 43025396)
-
(2006)
Lancet Oncology
, vol.7
, Issue.1
, pp. 77-82
-
-
Ha, P.K.1
Califano, J.A.2
-
11
-
-
0345357773
-
Gene silencing in cancer in associationwith promoter hypermethylation
-
DOI 10.1056/NEJMra023075
-
Herman JG, Baylin SB. (2003). Gene silencing in cancer in associationwith promoter hypermethylation. N Engl J Med 349: 2042-2054. (Pubitemid 37448928)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.21
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
12
-
-
67650999875
-
The basics of epithelial-mesenchymaltransition
-
Kalluri R, Weinberg RA. (2009). The basics of epithelial- mesenchymaltransition. J Clin Invest 119: 1420-1428.
-
(2009)
J Clin Invest
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
13
-
-
42049104107
-
Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer
-
DOI 10.1158/0008-5472.CAN-07-5194
-
Kozaki K, Imoto I, Mogi S, Omura K, Inazawa J. (2008). Explorationof tumor-suppressive microRNAs silenced by DNA hypermethylationin oral cancer. Cancer Res 68: 2094-2105. (Pubitemid 351521781)
-
(2008)
Cancer Research
, vol.68
, Issue.7
, pp. 2094-2105
-
-
Kozaki, K.-I.1
Imoto, I.2
Mogi, S.3
Omura, K.4
Inazawa, J.5
-
14
-
-
30444458822
-
-
The Editorial Board of Cancer Statistics in Japan Cancer Statistics in Japan 2003
-
Nomura K, Sobue T, Nakatani H, Maehara M, Kiryu Y, Tsukuma H, et al., The Editorial Board of Cancer Statistics in Japan. (2005).Number of deaths and proportional mortality rates from malignantneoplasms by site in Japan. Cancer Statistics in Japan 2003 (http://ganjoho.jp/public/statistics/backnumber/2010- en.html), pp 36-39.
-
(2005)
Number of Deaths and Proportional Mortality Rates from Malignantneoplasms by Site in Japan
, pp. 36-39
-
-
Nomura, K.1
Sobue, T.2
Nakatani, H.3
Maehara, M.4
Kiryu, Y.5
Tsukuma, H.6
-
15
-
-
77954354936
-
Pancreatic cancers epigenetically silence SIP1 and hypomethylateand overexpress miR-200a/200b in association withelevated circulating miR-200a and miR-200b levels
-
Li A, Omura N, Hong SM, Vincent A, Walter K, Griffith M et al.(2010). Pancreatic cancers epigenetically silence SIP1 and hypomethylateand overexpress miR-200a/200b in association withelevated circulating miR-200a and miR-200b levels. Cancer Res70: 5226-5237.
-
(2010)
Cancer Res
, vol.70
, pp. 5226-5237
-
-
Li, A.1
Omura, N.2
Hong, S.M.3
Vincent, A.4
Walter, K.5
Griffith, M.6
-
16
-
-
77952954695
-
When pathways collide: Collaborationand connivance among signalling proteins in development
-
McNeill H, Woodgett JR. (2010). When pathways collide: collaborationand connivance among signalling proteins in development.Nature 11: 404-413.
-
(2010)
Nature
, vol.11
, pp. 404-413
-
-
McNeill, H.1
Woodgett, J.R.2
-
17
-
-
34548175512
-
Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression
-
DOI 10.1111/j.1349-7006.2007.00550.x
-
Moustakas A, Heldin CH. (2007). Signaling networks guidingepithelial- mesenchymal transitions during embryogenesis andcancer progression. Cancer Sci 98: 1512-1520. (Pubitemid 47308444)
-
(2007)
Cancer Science
, vol.98
, Issue.10
, pp. 1512-1520
-
-
Moustakas, A.1
Heldin, C.-H.2
-
18
-
-
0042337389
-
WNT7a induces E-cadherin in lung cancer cells
-
DOI 10.1073/pnas.1734137100
-
Ohira T, Gemmill RM, Ferguson K, Kusy S, Roche J, Brambilla Eet al. (2003). WNT7a induces E-cadherin in lung cancer cells. ProcNatl Acad Sci USA 100: 10429-10434. (Pubitemid 37071895)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.18
, pp. 10429-10434
-
-
Ohira, T.1
Gemmill, R.M.2
Ferguson, K.3
Kusy, S.4
Roche, J.5
Brambilla, E.6
Zeng, C.7
Baron, A.8
Bemis, L.9
Erickson, P.10
Wilder, E.11
Rustgi, A.12
Kitajewski, J.13
Gabrielson, E.14
Bremnes, R.15
Franklin, W.16
Drabkin, H.A.17
-
19
-
-
33845356420
-
Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets
-
DOI 10.1093/carcin/bgl161
-
Ordway JM, Bedell JA, Citek RW, Nunberg A, Garrido A, Kendall Ret al. (2006). Comprehensive DNA methylation profiling in a humancancer genome identifies novel epigenetic targets. Carcinogenesis 27:2409-2423. (Pubitemid 44884098)
-
(2006)
Carcinogenesis
, vol.27
, Issue.12
, pp. 2409-2423
-
-
Ordway, J.M.1
Bedell, J.A.2
Citek, R.W.3
Nunberg, A.4
Garrido, A.5
Kendall, R.6
Stevens, J.R.7
Cao, D.8
Doerge, R.W.9
Korshunova, Y.10
Holemon, H.11
McPherson, J.D.12
Lakey, N.13
Leon, J.14
Martienssen, R.A.15
Jeddeloh, J.A.16
-
20
-
-
76249084838
-
Smad signaling is required to maintain epigenetic silencingduring breast cancer progression
-
Papageorgis P, Lambert AW, Ozturk S, Gao F, Pan H, Manne U et al.(2010). Smad signaling is required to maintain epigenetic silencingduring breast cancer progression. Cancer Res 70: 968-978.
-
(2010)
Cancer Res
, vol.70
, pp. 968-978
-
-
Papageorgis, P.1
Lambert, A.W.2
Ozturk, S.3
Gao, F.4
Pan, H.5
Manne, U.6
-
21
-
-
41649091906
-
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
-
DOI 10.1101/gad.1640608
-
Park SM, Gaur AB, Lengyel E, Peter ME. (2008). The miR-200 familydetermines the epithelial phenotype of cancer cells by targeting theE-cadherin repressors ZEB1 and ZEB2. Genes Dev 22: 894-907. (Pubitemid 351482843)
-
(2008)
Genes and Development
, vol.22
, Issue.7
, pp. 894-907
-
-
Park, S.-M.1
Gaur, A.B.2
Lengyel, E.3
Peter, M.E.4
-
22
-
-
14944385553
-
Global cancer statistics,2002
-
Parkin DM, Bray F, Ferlay J, Pisani P. (2005). Global cancer statistics,2002. CA Cancer J Clin 55: 74-108.
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
23
-
-
0037742210
-
Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays
-
Sato N, Fukushima N, Maitra A, Matsubayashi H, Yeo CJ, CameronJL et al. (2003). Discovery of novel targets for aberrant methylationin pancreatic carcinoma using high-throughput microarrays. CancerRes 63: 3735-3742. (Pubitemid 36793060)
-
(2003)
Cancer Research
, vol.63
, Issue.13
, pp. 3735-3742
-
-
Sato, N.1
Fukushima, N.2
Maitra, A.3
Matsubayashi, H.4
Yeo, C.J.5
Cameron, J.L.6
Hruban, R.H.7
Goggins, M.8
-
24
-
-
0034192040
-
Genetic aberrations in oral or head and neck squamous cell carcinoma (SCCHN): 1. Carcinogen metabolism, DNA repair and cell cycle control
-
DOI 10.1016/S1368-8375(00)00007-5, PII S1368837500000075
-
Scully C, Field JK, Tanzawa H. (2000). Genetic aberrations in oral orhead and neck squamous cell carcinoma (SCCHN): 1. Carcinogenmetabolism, DNA repair and cell cycle control. Oral Oncol 36:256-263. (Pubitemid 30227706)
-
(2000)
Oral Oncology
, vol.36
, Issue.3
, pp. 256-263
-
-
Scully, C.1
Field, J.K.2
Tanzawa, H.3
-
25
-
-
77950293595
-
Loss of FOXA1/2 isessential for the epithelial-to-mesenchymal transition in pancreaticcancer
-
Song Y, Washington MK, Crawford HC. (2010). Loss of FOXA1/2 isessential for the epithelial-to-mesenchymal transition in pancreaticcancer. Cancer Res 70: 2115-2125.
-
(2010)
Cancer Res
, vol.70
, pp. 2115-2125
-
-
Song, Y.1
Washington, M.K.2
Crawford, H.C.3
-
26
-
-
37149000359
-
PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation
-
DOI 10.1038/sj.onc.1210589, PII 1210589
-
Suzuki E, Imoto I, Pimkhaokham A, Nakagawa T, Kamata N, KozakiK et al. (2007). PRTFDC1, a possible tumor-suppressor gene, isfrequently silenced in oral squamous-cell carcinomas by aberrantpromoter hypermethylation. Oncogene 26: 7921-7932. (Pubitemid 350261784)
-
(2007)
Oncogene
, vol.26
, Issue.57
, pp. 7921-7932
-
-
Suzuki, E.1
Imoto, I.2
Pimkhaokham, A.3
Nakagawa, T.4
Kamata, N.5
Kozaki, K.-I.6
Amagasa, T.7
Inazawa, J.8
-
27
-
-
0043063969
-
Down-regulation of Wnt-4 and up-regulation of Wnt-5a expression by epithelial-mesenchymal transition in human squamous carcinoma cells
-
DOI 10.1111/j.1349-7006.2003.tb01488.x
-
Taki M, Kamata N, Yokoyama K, Fujimoto R, Tsutsumi S, Nagayama M. (2003). Down-regulation of Wnt-4 and up-regulationof Wnt-5a expression by epithelial-mesenchymal transition inhuman squamous carcinoma cells. Cancer Sci 94: 593-597. (Pubitemid 36975013)
-
(2003)
Cancer Science
, vol.94
, Issue.7
, pp. 593-597
-
-
Taki, M.1
Kamata, N.2
Yokoyama, K.3
Fujimoto, R.4
Tsutsumi, S.5
Nagayama, M.6
-
28
-
-
70450198396
-
Epithelialmesenchymaltransitions in development and disease
-
Thiery JP, Acloque H, Huang RY, Nieto MA. (2009). Epithelialmesenchymaltransitions in development and disease. Cell 139:871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
29
-
-
21244440303
-
Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through Frizzled-9-mediated growth inhibition and promotion of cell differentiation
-
DOI 10.1074/jbc.M409392200
-
Winn RA, Marek L, Han SY, Rodriguez K, Rodriguez N, HammondM et al. (2005). Restoration of Wnt-7a expression reverses nonsmallcell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation.J Biol Chem 280: 19625-19634. (Pubitemid 41379485)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.20
, pp. 19625-19634
-
-
Winn, R.A.1
Marek, L.2
Han, S.-Y.3
Rodriguez, K.4
Rodriguez, N.5
Haimnond, M.6
Van Scoyk, M.7
Acosta, H.8
Mirus, J.9
Barry, N.10
Bren-Mattison, Y.11
Van Raay, T.J.12
Nemenoff, R.A.13
Heasley, L.E.14
-
30
-
-
44449144396
-
Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
-
DOI 10.1016/j.devcel.2008.05.009, PII S1534580708002098
-
Yang J, Weinberg RA. (2008). Epithelial-mesenchymal transition:at the crossroads of development and tumor metastasis. Dev Cell 14:818-829. (Pubitemid 351757205)
-
(2008)
Developmental Cell
, vol.14
, Issue.6
, pp. 818-829
-
-
Yang, J.1
Weinberg, R.A.2
|