Resident cardiac immune cells and expression of the ectonucleotidase enzymes CD39 and CD73 after ischemic injury

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Bönner, Florian ^a   Borg, Nadine ^a   Burghoff, Sandra ^a   Schrader, Jürgen ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

5' NUCLEOTIDASE; ADENINE NUCLEOTIDE; ADENOSINE TRIPHOSPHATE; CD31 ANTIGEN; CD39 ANTIGEN; CD45 ANTIGEN; ADENOSINE; APYRASE; LEUKOCYTE ANTIGEN;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; BONE MARROW CELL; CELL COMPARTMENTALIZATION; ENDOTHELIUM; ENDOTHELIUM CELL; ERYTHROCYTE; FEMALE; FLUORESCENCE ACTIVATED CELL SORTER; GRANULOCYTE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; IMMUNOCOMPETENT CELL; INFLAMMATION; LEUKOCYTE; LEUKOCYTE COUNT; LYMPHOID CELL; MONONUCLEAR CELL; MOUSE; NONHUMAN; NUCLEOTIDE METABOLISM; PROTEIN EXPRESSION; RESIDENT CARDIAC IMMUNE CELL; T LYMPHOCYTE; THROMBOCYTE; UPREGULATION; ANIMAL; B LYMPHOCYTE; C57BL MOUSE; CELL CULTURE; FLOW CYTOMETRY; HEART INFARCTION; METABOLISM;

MURINAE;

5'-NUCLEOTIDASE; ADENOSINE; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIGENS, CD; APYRASE; B-LYMPHOCYTES; CELLS, CULTURED; ERYTHROCYTES; FEMALE; FLOW CYTOMETRY; GRANULOCYTES; LEUKOCYTES; MICE; MICE, INBRED C57BL; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; T-LYMPHOCYTES;

EID: 84859702798     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034730     Document Type: Article

References (44)

1. Rock KL, Latz E, Ontiveros F, Kono H, (2010) The sterile inflammatory response. Annu Rev Immunol 28: 321-342.
2. Frangogiannis NG, (2008) The immune system and cardiac repair. Pharmacol Res 58: 88-111.
3. Junger WG, (2011) Immune cell regulation by autocrine purinergic signalling. Nat Rev Immunol 11: 201-212.
4. Nahrendorf M, Pittet MJ, Swirski FK, (2010) Monocytes: protagonists of infarct inflammation and repair after myocardial infarction. Circulation 121: 2437-2445.
5. van den Borne SW, Diez J, Blankesteijn WM, Verjans J, Hofstra L, et al. (2010) Myocardial remodeling after infarction: the role of myofibroblasts. Nat Rev Cardiol 7: 30-37.
6. Galkina E, Kadl A, Sanders J, Varughese D, Sarembock IJ, et al. (2006) Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent. J Exp Med 203: 1273-1282.
7. Bulloch K, Miller MM, Gal-Toth J, Milner TA, Gottfried-Blackmore A, et al. (2008) CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain. J Comp Neurol 508: 687-710.
8. Ochoa MT, Loncaric A, Krutzik SR, Becker TC, Modlin RL, (2008) "Dermal dendritic cells" comprise two distinct populations: CD1+ dendritic cells and CD209+ macrophages. J Invest Dermatol 128: 2225-2231.
9. Devey L, Ferenbach D, Mohr E, Sangster K, Bellamy CO, et al. (2009) Tissue-resident macrophages protect the liver from ischemia reperfusion injury via a heme oxygenase-1-dependent mechanism. Mol Ther 17: 65-72.
10. Tadagavadi RK, Reeves WB, (2010) Renal dendritic cells ameliorate nephrotoxic acute kidney injury. J Am Soc Nephrol 21: 53-63.
11. Koszalka P, Ozuyaman B, Huo Y, Zernecke A, Flogel U, et al. (2004) Targeted disruption of cd73/ecto-5′-nucleotidase alters thromboregulation and augments vascular inflammatory response. Circ Res 95: 814-821.
12. Eltzschig HK, Thompson LF, Karhausen J, Cotta RJ, Ibla JC, et al. (2004) Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism. Blood 104: 3986-3992.
13. Yegutkin GG, (2008) Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade. Biochim Biophys Acta 1783: 673-694.
14. Eltzschig HK, Eckle T, Mager A, Kuper N, Karcher C, et al. (2006) ATP release from activated neutrophils occurs via connexin 43 and modulates adenosine-dependent endothelial cell function. Circ Res 99: 1100-1108.
15. Schenk U, Westendorf AM, Radaelli E, Casati A, Ferro M, et al. (2008) Purinergic control of T cell activation by ATP released through pannexin-1 hemichannels. Sci Signal 1: ra6.
16. Praetorius HA, Leipziger J, (2009) ATP release from non-excitable cells. Purinergic Signal 5: 433-446.
17. Pellegatti P, Falzoni S, Pinton P, Rizzuto R, Di VF, (2005) A novel recombinant plasma membrane-targeted luciferase reveals a new pathway for ATP secretion. Mol Biol Cell 16: 3659-3665.
18. Hasko G, Linden J, Cronstein B, Pacher P, (2008) Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nat Rev Drug Discov 7: 759-770.
19. Fredholm BB, Chern Y, Franco R, Sitkovsky M, (2007) Aspects of the general biology of adenosine A2A signaling. Prog Neurobiol 83: 263-276.
20. Bours MJ, Swennen EL, Di VF, Cronstein BN, Dagnelie PC, (2006) Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther 112: 358-404.
21. Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, et al. (2007) The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med 204: 3037-3047.
22. Fiset C, Clark RB, Larsen TS, Giles WR, (1997) A rapidly activating sustained K+ current modulates repolarization and excitation-contraction coupling in adult mouse ventricle. J Physiol 504 (Pt 3): 557-563.
23. Zhou YY, Wang SQ, Zhu WZ, Chruscinski A, Kobilka BK, et al. (2000) Culture and adenoviral infection of adult mouse cardiac myocytes: methods for cellular genetic physiology. Am J Physiol Heart Circ Physiol 279: H429-H436.
24. Gonzalez-Juarrero M, Shim TS, Kipnis A, Junqueira-Kipnis AP, Orme IM, (2003) Dynamics of macrophage cell populations during murine pulmonary tuberculosis. J Immunol 171: 3128-3135.
25. Geissmann F, Gordon S, Hume DA, Mowat AM, Randolph GJ, (2010) Unravelling mononuclear phagocyte heterogeneity. Nat Rev Immunol 10: 453-460.
26. Novobrantseva TI, Majeau GR, Amatucci A, Kogan S, Brenner I, et al. (2005) Attenuated liver fibrosis in the absence of B cells. J Clin Invest 115: 3072-3082.
27. Soos TJ, Sims TN, Barisoni L, Lin K, Littman DR, et al. (2006) CX3CR1+ interstitial dendritic cells form a contiguous network throughout the entire kidney. Kidney Int 70: 591-596.
28. Gachet C, (2006) Regulation of platelet functions by P2 receptors. Annu Rev Pharmacol Toxicol 46: 277-300.
29. Arciero JC, Carlson BE, Secomb TW, (2008) Theoretical model of metabolic blood flow regulation: roles of ATP release by red blood cells and conducted responses. Am J Physiol Heart Circ Physiol 295: H1562-H1571.
30. Wong CW, Christen T, Roth I, Chadjichristos CE, Derouette JP, et al. (2006) Connexin37 protects against atherosclerosis by regulating monocyte adhesion. Nat Med 12: 950-954.
31. Idzko M, Hammad H, van Nimwegen M, Kool M, Willart MAM, et al. (2007) Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells. Nature Medicine 13: 913-919.
32. Mizumoto N, Kumamoto T, Robson SC, Sevigny J, Matsue H, et al. (2002) CD39 is the dominant Langerhans cell associated ecto-NTPDase: Modulatory roles in inflammation and immune responsiveness. Nature Medicine 8: 358-365.
33. Elliott MR, Chekeni FB, Trampont PC, Lazarowski ER, Kadl A, et al. (2009) Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature 461: 282-U165.
34. Robson SC, Sevigny J, Zimmermann H, (2006) The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance. Purinergic Signal 2: 409-430.
35. Levesque SA, Kukulski F, Enjyoji K, Robson SC, Sevigny J, (2010) NTPDase1 governs P2X(7)-dependent functions in murine macrophages. European Journal of Immunology 40: 1473-1485.
36. Serra S, Horenstein AL, Vaisitti T, Brusa D, Rossi D, et al. (2011) CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death. Blood 118: 6141-6152.
37. Henttinen T, Jalkanen S, Yegutkin GG, (2003) Adherent leukocytes prevent adenosine formation and impair endothelial barrier function by Ecto-5′-nucleotidase/CD73-dependent mechanism. J Biol Chem 278: 24888-24895.
38. Romio M, Reinbeck B, Bongardt S, Huls S, Burghoff S, et al. (2011) Extracellular purine metabolism and signaling of CD73-derived adenosine in murine Treg and Teff cells. Am J Physiol Cell Physiol 301: C530-C539.
39. Salmon JE, Cronstein BN, (1990) Fc gamma receptor-mediated functions in neutrophils are modulated by adenosine receptor occupancy. A1 receptors are stimulatory and A2 receptors are inhibitory. J Immunol 145: 2235-2240.
40. Save S, Mohlin C, Vumma R, Persson K, (2011) Activation of adenosine A2A receptors inhibits neutrophil transuroepithelial migration. Infect Immun 79: 3431-3437.
41. Robson SC, Kaczmarek E, Siegel JB, Candinas D, Koziak K, et al. (1997) Loss of ATP diphosphohydrolase activity with endothelial cell activation. Journal of Experimental Medicine 185: 153-163.
42. Candinas D, Koyamada N, Miyatake T, Siegel J, Hancock WW, et al. (1996) Loss of rat glomerular ATP diphosphohydrolase activity during reperfusion injury is associated with oxidative stress reactions. Thrombosis and Haemostasis 76: 807-812.
43. Eltzschig HK, Ibla JC, Furuta GT, Leonard MO, Jacobson KA, et al. (2003) Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors. J Exp Med 198: 783-796.
44. Enjyoji K, Sevigny J, Lin Y, Frenette PS, Christie PD, et al. (1999) Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation. Nat Med 5: 1010-1017.