메뉴 건너뛰기




Volumn 9, Issue 2, 2012, Pages 338-348

Accelerating Discovery for Complex Neurological and Behavioral Disorders Through Systems Genetics and Integrative Genomics in the Laboratory Mouse

Author keywords

Bioinformatics; Data integration; genomics; Recombinant inbred mice; Systems genetics

Indexed keywords

BUNGAROTOXIN RECEPTOR; DOPAMINE 2 RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; PURINERGIC P2X4 RECEPTOR; SEROTONIN TRANSPORTER; SODIUM CHANNEL NAV1.6; SODIUM CHANNEL NAV1.7; VANILLOID RECEPTOR 1;

EID: 84859702330     PISSN: 19337213     EISSN: 18787479     Source Type: Journal    
DOI: 10.1007/s13311-012-0111-3     Document Type: Review
Times cited : (12)

References (61)
  • 1
    • 77955671522 scopus 로고    scopus 로고
    • Revised NESARC personality disorder diagnoses: gender, prevalence, and comorbidity with substance dependence disorders
    • Trull TJ, Jahng S, Tomko RL, Wood PK, Sher KJ. Revised NESARC personality disorder diagnoses: gender, prevalence, and comorbidity with substance dependence disorders. J Pers Disord 2010; 24: 412-426.
    • (2010) J Pers Disord , vol.24 , pp. 412-426
    • Trull, T.J.1    Jahng, S.2    Tomko, R.L.3    Wood, P.K.4    Sher, K.J.5
  • 2
    • 24644451045 scopus 로고    scopus 로고
    • Comorbidity between DSM-IV alcohol and specific drug use disorders in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions
    • Stinson FS, Grant BF, Dawson DA, et al. Comorbidity between DSM-IV alcohol and specific drug use disorders in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Drug Alcohol Depend 2005; 80: 105-116.
    • (2005) Drug Alcohol Depend , vol.80 , pp. 105-116
    • Stinson, F.S.1    Grant, B.F.2    Dawson, D.A.3
  • 3
    • 36849056661 scopus 로고    scopus 로고
    • The alcohol use disorder and associated disabilities interview schedule-IV (AUDADIS-IV): reliability of new psychiatric diagnostic modules and risk factors in a general population sample
    • Ruan WJ, Goldstein RB, Chou SP, et al. The alcohol use disorder and associated disabilities interview schedule-IV (AUDADIS-IV): reliability of new psychiatric diagnostic modules and risk factors in a general population sample. Drug Alcohol Depend 2008; 92: 27-36.
    • (2008) Drug Alcohol Depend , vol.92 , pp. 27-36
    • Ruan, W.J.1    Goldstein, R.B.2    Chou, S.P.3
  • 4
    • 57649100170 scopus 로고    scopus 로고
    • Physical pain, common psychiatric and substance use disorders, and the non-medical use of prescription analgesics in the United States
    • Novak SP, Herman-Stahl M, Flannery B, Zimmerman M. Physical pain, common psychiatric and substance use disorders, and the non-medical use of prescription analgesics in the United States. Drug Alcohol Depend 2009; 100: 63-70.
    • (2009) Drug Alcohol Depend , vol.100 , pp. 63-70
    • Novak, S.P.1    Herman-Stahl, M.2    Flannery, B.3    Zimmerman, M.4
  • 5
    • 79952312976 scopus 로고    scopus 로고
    • The prevalence and clinical implications of self-medication among individuals with anxiety disorders
    • Menary KR, Kushner MG, Maurer E, Thuras P. The prevalence and clinical implications of self-medication among individuals with anxiety disorders. J Anxiety Disord 2011; 25: 335-339.
    • (2011) J Anxiety Disord , vol.25 , pp. 335-339
    • Menary, K.R.1    Kushner, M.G.2    Maurer, E.3    Thuras, P.4
  • 6
    • 65549122081 scopus 로고    scopus 로고
    • Pathways between nonmedical opioid use/dependence and psychiatric disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions
    • Martins SS, Keyes KM, Storr CL, Zhu H, Chilcoat HD. Pathways between nonmedical opioid use/dependence and psychiatric disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Drug Alcohol Depend 2009; 103: 16-24.
    • (2009) Drug Alcohol Depend , vol.103 , pp. 16-24
    • Martins, S.S.1    Keyes, K.M.2    Storr, C.L.3    Zhu, H.4    Chilcoat, H.D.5
  • 7
    • 77950855881 scopus 로고    scopus 로고
    • Inhalant use, inhalant-use disorders, and antisocial behavior: findings from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)
    • Howard MO, Perron BE, Vaughn MG, Bender KA, Garland E. Inhalant use, inhalant-use disorders, and antisocial behavior: findings from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). J Stud Alcohol Drugs 2010; 71: 201-209. d.
    • (2010) J Stud Alcohol Drugs , vol.71 , pp. 201-209
    • Howard, M.O.1    Perron, B.E.2    Vaughn, M.G.3    Bender, K.A.4    Garland, E.5
  • 8
    • 48749109884 scopus 로고    scopus 로고
    • Nicotine dependence and mental disorders among adults in the USA: evaluating the role of the mode of administration
    • Goodwin RD, Zvolensky MJ, Keyes KM. Nicotine dependence and mental disorders among adults in the USA: evaluating the role of the mode of administration. Psychol Med 2008; 38: 1277-1286.
    • (2008) Psychol Med , vol.38 , pp. 1277-1286
    • Goodwin, R.D.1    Zvolensky, M.J.2    Keyes, K.M.3
  • 9
    • 24044478779 scopus 로고    scopus 로고
    • The association between stress and drinking: modifying effects of gender and vulnerability
    • Dawson DA, Grant BF, Ruan WJ. The association between stress and drinking: modifying effects of gender and vulnerability. Alcohol Alcohol 2005; 40: 453-460.
    • (2005) Alcohol Alcohol , vol.40 , pp. 453-460
    • Dawson, D.A.1    Grant, B.F.2    Ruan, W.J.3
  • 10
    • 67349278471 scopus 로고    scopus 로고
    • Self-medication of mood disorders with alcohol and drugs in the National Epidemiologic Survey on Alcohol and Related Conditions
    • Bolton JM, Robinson J, Sareen J. Self-medication of mood disorders with alcohol and drugs in the National Epidemiologic Survey on Alcohol and Related Conditions. J Affect Disord 2009; 115: 367-375.
    • (2009) J Affect Disord , vol.115 , pp. 367-375
    • Bolton, J.M.1    Robinson, J.2    Sareen, J.3
  • 11
    • 33644823142 scopus 로고    scopus 로고
    • Lifetime comorbidity of DSM-IV mood and anxiety disorders and specific drug use disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions
    • Conway KP, Compton W, Stinson FS, Grant BF. Lifetime comorbidity of DSM-IV mood and anxiety disorders and specific drug use disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. J Clin Psychiatry 2006; 67: 247-257.
    • (2006) J Clin Psychiatry , vol.67 , pp. 247-257
    • Conway, K.P.1    Compton, W.2    Stinson, F.S.3    Grant, B.F.4
  • 12
    • 79957658264 scopus 로고    scopus 로고
    • Genetic analysis of complex traits in the emerging Collaborative Cross
    • Aylor DL, Valdar W, Foulds-Mathes W, et al. Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res 2011; 21: 1213-1222.
    • (2011) Genome Res , vol.21 , pp. 1213-1222
    • Aylor, D.L.1    Valdar, W.2    Foulds-Mathes, W.3
  • 13
    • 52549103273 scopus 로고    scopus 로고
    • The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics
    • Chesler EJ, Miller DR, Branstetter LR, et al. The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics. Mamm Genome 2008; 19: 382-389.
    • (2008) Mamm Genome , vol.19 , pp. 382-389
    • Chesler, E.J.1    Miller, D.R.2    Branstetter, L.R.3
  • 16
    • 70449134639 scopus 로고    scopus 로고
    • Ontological discovery environment: a system for integrating gene-phenotype associations
    • Baker EJ, Jay JJ, Philip VM, et al. Ontological discovery environment: a system for integrating gene-phenotype associations. Genomics 2009; 94: 377-387.
    • (2009) Genomics , vol.94 , pp. 377-387
    • Baker, E.J.1    Jay, J.J.2    Philip, V.M.3
  • 17
    • 77956143953 scopus 로고    scopus 로고
    • Identifying quantitative trait loci (QTLs) and genes (QTGs) for alcohol-related phenotypes in mice
    • Milner LC, Buck KJ. Identifying quantitative trait loci (QTLs) and genes (QTGs) for alcohol-related phenotypes in mice. Int Rev Neurobiol 2010; 91: 173-204.
    • (2010) Int Rev Neurobiol , vol.91 , pp. 173-204
    • Milner, L.C.1    Buck, K.J.2
  • 18
    • 84859727275 scopus 로고    scopus 로고
    • The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse
    • Eppig JT, Blake JA, Bult CJ, Kadin JA, Richardson JE. The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse. Nucleic Acids Res 2012; 40: D881-D886.
    • (2012) Nucleic Acids Res , vol.40
    • Eppig, J.T.1    Blake, J.A.2    Bult, C.J.3    Kadin, J.A.4    Richardson, J.E.5
  • 19
    • 0025744331 scopus 로고
    • Use of recombinant inbred strains to identify quantitative trait loci in psychopharmacology
    • Gora-Maslak G, McClearn GE, Crabbe JC, et al. Use of recombinant inbred strains to identify quantitative trait loci in psychopharmacology. Psychopharmacology (Berl) 1991; 104: 413-424.
    • (1991) Psychopharmacology (Berl) , vol.104 , pp. 413-424
    • Gora-Maslak, G.1    McClearn, G.E.2    Crabbe, J.C.3
  • 20
    • 2142652098 scopus 로고    scopus 로고
    • WebQTL: rapid exploratory analysis of gene expression and genetic networks for brain and behavior
    • Chesler EJ, Lu L, Wang J, Williams RW, Manly KF. WebQTL: rapid exploratory analysis of gene expression and genetic networks for brain and behavior. Nat Neurosci 2004; 7: 485-486.
    • (2004) Nat Neurosci , vol.7 , pp. 485-486
    • Chesler, E.J.1    Lu, L.2    Wang, J.3    Williams, R.W.4    Manly, K.F.5
  • 21
    • 25444501564 scopus 로고    scopus 로고
    • A new set of BXD recombinant inbred lines from advanced intercross populations in mice
    • Peirce JL, Lu L, Gu J, Silver LM, Williams RW. A new set of BXD recombinant inbred lines from advanced intercross populations in mice. BMC Genet 2004; 5: 7.
    • (2004) BMC Genet , vol.5 , Issue.7
    • Peirce, J.L.1    Lu, L.2    Gu, J.3    Silver, L.M.4    Williams, R.W.5
  • 22
    • 77949344299 scopus 로고    scopus 로고
    • High-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains
    • Philip VM, Duvvuru S, Gomero B, et al. High-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains. Genes Brain Behav 2010; 9: 129-159.
    • (2010) Genes Brain Behav , vol.9 , pp. 129-159
    • Philip, V.M.1    Duvvuru, S.2    Gomero, B.3
  • 23
    • 0242353110 scopus 로고    scopus 로고
    • Genetic correlates of gene expression in recombinant inbred strains: a relational model system to explore neurobehavioral phenotypes
    • Chesler EJ, Wang J, Lu L, et al. Genetic correlates of gene expression in recombinant inbred strains: a relational model system to explore neurobehavioral phenotypes. Neuroinformatics 2003; 1: 343-357.
    • (2003) Neuroinformatics , vol.1 , pp. 343-357
    • Chesler, E.J.1    Wang, J.2    Lu, L.3
  • 24
    • 0035164656 scopus 로고    scopus 로고
    • Map Manager QTX, cross-platform software for genetic mapping
    • Manly KF, Cudmore RH Jr., Meer JM. Map Manager QTX, cross-platform software for genetic mapping. Mamm Genome 2001; 12: 930-932.
    • (2001) Mamm Genome , vol.12 , pp. 930-932
    • Manly, K.F.1    Cudmore Jr., R.H.2    Meer, J.M.3
  • 25
    • 80053217520 scopus 로고    scopus 로고
    • Adolescent personality profiles, neighborhood income, and young adult alcohol use: a longitudinal study
    • Ayer L, Rettew D, Althoff RR, et al. Adolescent personality profiles, neighborhood income, and young adult alcohol use: a longitudinal study. Addict Behav 2011; 36: 1301-1304.
    • (2011) Addict Behav , vol.36 , pp. 1301-1304
    • Ayer, L.1    Rettew, D.2    Althoff, R.R.3
  • 26
    • 34447505156 scopus 로고    scopus 로고
    • DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: implications for eQTL mapping studies
    • Hovatta I, Zapala MA, Broide RS, et al. DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: implications for eQTL mapping studies. Genome Biol 2007; 8: R25.
    • (2007) Genome Biol , vol.8 , pp. 25
    • Hovatta, I.1    Zapala, M.A.2    Broide, R.S.3
  • 27
    • 33646841491 scopus 로고    scopus 로고
    • Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes
    • Lum PY, Chen Y, Zhu J, et al. Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes. J Neurochem 2006;(97 suppl 1): 50-62.
    • (2006) J Neurochem , vol.97 , Issue.SUPPL. 1 , pp. 50-62
    • Lum, P.Y.1    Chen, Y.2    Zhu, J.3
  • 28
    • 79952602299 scopus 로고    scopus 로고
    • Gene networks associated with conditional fear in mice identified using a systems genetics approach
    • Park CC, Gale GD, de Jong S, et al. Gene networks associated with conditional fear in mice identified using a systems genetics approach. BMC Syst Biol 2011; 5: 43.
    • (2011) BMC Syst Biol , vol.5 , pp. 43
    • Park, C.C.1    Gale, G.D.2    de Jong, S.3
  • 29
    • 34548432163 scopus 로고    scopus 로고
    • Chromosome substitution strains: a new way to study genetically complex traits
    • Hill AE, Lander ES, Nadeau JH. Chromosome substitution strains: a new way to study genetically complex traits. Methods Mol Med 2006; 128: 153-172.
    • (2006) Methods Mol Med , vol.128 , pp. 153-172
    • Hill, A.E.1    Lander, E.S.2    Nadeau, J.H.3
  • 30
    • 70449382310 scopus 로고    scopus 로고
    • A major QTL on chromosome 11 influences psychostimulant and opioid sensitivity in mice
    • Bryant CD, Chang HP, Zhang J, et al. A major QTL on chromosome 11 influences psychostimulant and opioid sensitivity in mice. Genes Brain Behav 2009; 8: 795-805.
    • (2009) Genes Brain Behav , vol.8 , pp. 795-805
    • Bryant, C.D.1    Chang, H.P.2    Zhang, J.3
  • 31
    • 46149123186 scopus 로고    scopus 로고
    • Genetic mapping of vocalization to a series of increasing acute footshocks using B6.A consomic and B6.D2 congenic mouse strains
    • Matthews DB, Chesler EJ, Cook MN, et al. Genetic mapping of vocalization to a series of increasing acute footshocks using B6. A consomic and B6. D2 congenic mouse strains. Behav Genet 2008; 38: 417-423.
    • (2008) Behav Genet , vol.38 , pp. 417-423
    • Matthews, D.B.1
  • 32
    • 0028803358 scopus 로고
    • Advanced intercross lines, an experimental population for fine genetic mapping
    • Darvasi A, Soller M. Advanced intercross lines, an experimental population for fine genetic mapping. Genetics 1995; 141: 1199-1207.
    • (1995) Genetics , vol.141 , pp. 1199-1207
    • Darvasi, A.1    Soller, M.2
  • 33
    • 15544389227 scopus 로고    scopus 로고
    • Mouse inbred strain sequence information and yin-yang crosses for quantitative trait locus fine mapping
    • Shifman S, Darvasi A. Mouse inbred strain sequence information and yin-yang crosses for quantitative trait locus fine mapping. Genetics 2005; 169: 849-854.
    • (2005) Genetics , vol.169 , pp. 849-854
    • Shifman, S.1    Darvasi, A.2
  • 34
    • 77955654603 scopus 로고    scopus 로고
    • Quantitative trait locus and haplotype mapping in closely related inbred strains identifies a locus for open field behavior
    • Eisener-Dorman AF, Grabowski-Boase L, Steffy BM, Wiltshire T, Tarantino LM. Quantitative trait locus and haplotype mapping in closely related inbred strains identifies a locus for open field behavior. Mamm Genome 2010; 21: 231-246.
    • (2010) Mamm Genome , vol.21 , pp. 231-246
    • Eisener-Dorman, A.F.1    Grabowski-Boase, L.2    Steffy, B.M.3    Wiltshire, T.4    Tarantino, L.M.5
  • 35
    • 34548423292 scopus 로고    scopus 로고
    • The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics
    • Roberts A, Pardo-Manuel de Villena F, Wang W, McMillan L, Threadgill DW. The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics. Mamm Genome 2007; 18: 473-481.
    • (2007) Mamm Genome , vol.18 , pp. 473-481
    • Roberts, A.1    de Pardo-Manuel, V.F.2    Wang, W.3    McMillan, L.4    Threadgill, D.W.5
  • 36
    • 61449224751 scopus 로고    scopus 로고
    • A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: the NIH heterogeneous stock
    • Johannesson M, Lopez-Aumatell R, Stridh P, et al. A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: the NIH heterogeneous stock. Genome Res 2009; 19: 150-158.
    • (2009) Genome Res , vol.19 , pp. 150-158
    • Johannesson, M.1    Lopez-Aumatell, R.2    Stridh, P.3
  • 38
    • 14644441018 scopus 로고    scopus 로고
    • The Collaborative Cross, a community resource for the genetic analysis of complex traits
    • Churchill GA, Airey DC, Allayee H, et al. The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet 2004; 36: 1133-1137.
    • (2004) Nat Genet , vol.36 , pp. 1133-1137
    • Churchill, G.A.1    Airey, D.C.2    Allayee, H.3
  • 39
    • 77957894341 scopus 로고    scopus 로고
    • Genetic diversity and striatal gene networks: focus on the heterogeneous stock-collaborative cross (HS-CC) mouse
    • Iancu OD, Darakjian P, Walter NA, et al. Genetic diversity and striatal gene networks: focus on the heterogeneous stock-collaborative cross (HS-CC) mouse. BMC Genomics 2010; 11: 585.
    • (2010) BMC Genomics , vol.11 , pp. 585
    • Iancu, O.D.1    Darakjian, P.2    Walter, N.A.3
  • 40
    • 84857410370 scopus 로고    scopus 로고
    • The Mouse Diversity Outbred Population
    • Svenson KL, Gatti DM, Valdar W, et al. The Mouse Diversity Outbred Population. Genetics 2012; 190: 437-447.
    • (2012) Genetics , vol.190 , pp. 437-447
    • Svenson, K.L.1    Gatti, D.M.2    Valdar, W.3
  • 41
    • 33846461151 scopus 로고    scopus 로고
    • Genetic and structural analysis of the basolateral amygdala complex in BXD recombinant inbred mice
    • Mozhui K, Hamre KM, Holmes A, Lu L, Williams RW. Genetic and structural analysis of the basolateral amygdala complex in BXD recombinant inbred mice. Behav Genet 2007; 37: 223-243.
    • (2007) Behav Genet , vol.37 , pp. 223-243
    • Mozhui, K.1    Hamre, K.M.2    Holmes, A.3    Lu, L.4    Williams, R.W.5
  • 42
    • 29644445238 scopus 로고    scopus 로고
    • Quantitative trait loci that determine BMD in C57BL/6J and 129S1/SvImJ inbred mice
    • Ishimori N, Li R, Walsh KA, et al. Quantitative trait loci that determine BMD in C57BL/6J and 129S1/SvImJ inbred mice. J Bone Miner Res 2006; 21: 105-112.
    • (2006) J Bone Miner Res , vol.21 , pp. 105-112
    • Ishimori, N.1    Li, R.2    Walsh, K.A.3
  • 43
    • 20144386111 scopus 로고    scopus 로고
    • Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function
    • Chesler EJ, Lu L, Shou S, et al. Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function. Nat Genet 2005; 37: 233-242.
    • (2005) Nat Genet , vol.37 , pp. 233-242
    • Chesler, E.J.1    Lu, L.2    Shou, S.3
  • 44
    • 78649506588 scopus 로고    scopus 로고
    • A unified framework for biomedical terminologies and ontologies
    • Ceusters W, Smith B. A unified framework for biomedical terminologies and ontologies. Stud Health Technol Inform 2010; 160(pt 2): 1050-1054.
    • (2010) Stud Health Technol Inform , vol.160 , Issue.pt 2 , pp. 1050-1054
    • Ceusters, W.1    Smith, B.2
  • 45
    • 84859699831 scopus 로고    scopus 로고
    • The Gene Ontology: Enhancements for 2011. Nucleic Acids Res 2012; 40: D559-D564.
    • (2012) Nucleic Acids Res , vol.40
  • 46
    • 84859699832 scopus 로고    scopus 로고
    • Disease Ontology: A backbone for disease semantic integration
    • Schriml LM, Arze C, Nadendla S, et al. Disease Ontology: A backbone for disease semantic integration. Nucleic Acids Res 2012; 40: D940-D946.
    • (2012) Nucleic Acids Res , vol.40
    • Schriml, L.M.1    Arze, C.2    Nadendla, S.3
  • 47
    • 78249235739 scopus 로고    scopus 로고
    • The mammalian phenotype ontology: enabling robust annotation and comparative analysis
    • Smith CL, Eppig JT. The mammalian phenotype ontology: enabling robust annotation and comparative analysis. Wiley Interdiscip Rev Syst Biol Med 2009; 1: 390-399.
    • (2009) Wiley Interdiscip Rev Syst Biol Med , vol.1 , pp. 390-399
    • Smith, C.L.1    Eppig, J.T.2
  • 48
    • 33846045023 scopus 로고    scopus 로고
    • SynDB: a Synapse protein DataBase based on synapse ontology
    • Zhang W, Zhang Y, Zheng H, et al. SynDB: a Synapse protein DataBase based on synapse ontology. Nucleic Acids Res 2007; 35(database issue): D737-D741.
    • (2007) Nucleic Acids Res , vol.35 , Issue.database issue
    • Zhang, W.1    Zhang, Y.2    Zheng, H.3
  • 49
    • 58149204060 scopus 로고    scopus 로고
    • ERGR: An ethanol-related gene resource
    • Guo AY, Webb BT, Miles MF, et al. ERGR: An ethanol-related gene resource. Nucleic Acids Res 2009; 37(database issue): D840-D845.
    • (2009) Nucleic Acids Res , vol.37 , Issue.database issue
    • Guo, A.Y.1    Webb, B.T.2    Miles, M.F.3
  • 50
    • 38949164506 scopus 로고    scopus 로고
    • Genes and (common) pathways underlying drug addiction
    • Li CY, Mao X, Wei L. Genes and (common) pathways underlying drug addiction. PLoS Comput Biol 2008; 4: e2.
    • (2008) PLoS Comput Biol , vol.4
    • Li, C.Y.1    Mao, X.2    Wei, L.3
  • 51
    • 34547545164 scopus 로고    scopus 로고
    • The Pain Genes Database: An interactive web browser of pain-related transgenic knockout studies
    • Lacroix-Fralish ML, Ledoux JB, Mogil JS. The Pain Genes Database: An interactive web browser of pain-related transgenic knockout studies. Pain 2007; 131: e1-e4.
    • (2007) Pain , vol.131
    • Lacroix-Fralish, M.L.1    Ledoux, J.B.2    Mogil, J.S.3
  • 52
    • 58549092240 scopus 로고    scopus 로고
    • The neuroscience information framework: a data and knowledge environment for neuroscience
    • Gardner D, Akil H, Ascoli GA, et al. The neuroscience information framework: a data and knowledge environment for neuroscience. Neuroinformatics 2008; 6: 149-160.
    • (2008) Neuroinformatics , vol.6 , pp. 149-160
    • Gardner, D.1    Akil, H.2    Ascoli, G.A.3
  • 54
    • 78651317084 scopus 로고    scopus 로고
    • The Comparative Toxicogenomics Database: update 2011
    • Davis AP, King BL, Mockus S, et al. The Comparative Toxicogenomics Database: update 2011. Nucleic Acids Res 2012; 39(database issue): D1067-D1072.
    • (2012) Nucleic Acids Res , vol.39 , Issue.database issue
    • Davis, A.P.1    King, B.L.2    Mockus, S.3
  • 55
    • 33846252240 scopus 로고    scopus 로고
    • Genome-wide atlas of gene expression in the adult mouse brain
    • Lein ES, Hawrylycz MJ, Ao N, et al. Genome-wide atlas of gene expression in the adult mouse brain. Nature 2007; 445: 168-176.
    • (2007) Nature , vol.445 , pp. 168-176
    • Lein, E.S.1    Hawrylycz, M.J.2    Ao, N.3
  • 56
    • 78149472321 scopus 로고    scopus 로고
    • A genome-wide Drosophila screen for heat nociception identifies alpha2delta3 as an evolutionarily conserved pain gene
    • Neely GG, Hess A, Costigan M, et al. A genome-wide Drosophila screen for heat nociception identifies alpha2delta3 as an evolutionarily conserved pain gene. Cell 2010; 143: 628-638.
    • (2010) Cell , vol.143 , pp. 628-638
    • Neely, G.G.1    Hess, A.2    Costigan, M.3
  • 58
    • 77952735731 scopus 로고    scopus 로고
    • Coming to grips with complex disorders: genetic risk prediction in bipolar disorder using panels of genes identified through convergent functional genomics
    • Patel SD, Le-Niculescu H, Koller DL, et al. Coming to grips with complex disorders: genetic risk prediction in bipolar disorder using panels of genes identified through convergent functional genomics. Am J Med Genet B Neuropsychiatr Genet 2010; 153B: 850-877.
    • (2010) Am J Med Genet B Neuropsychiatr Genet , vol.153 B , pp. 850-877
    • Patel, S.D.1
  • 59
    • 77950900465 scopus 로고    scopus 로고
    • Systematic discovery of nonobvious human disease models through orthologous phenotypes
    • McGary KL, Park TJ, Woods JO, et al. Systematic discovery of nonobvious human disease models through orthologous phenotypes. Proc Natl Acad Sci U S A 2010; 107: 6544-6549.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 6544-6549
    • McGary, K.L.1
  • 60
  • 61
    • 77956272138 scopus 로고    scopus 로고
    • Susceptibility to chronic pain following nerve injury is genetically affected by CACNG2
    • Nissenbaum J, Devor M, Seltzer Z, et al. Susceptibility to chronic pain following nerve injury is genetically affected by CACNG2. Genome Res 2010; 20: 1180-1190.
    • (2010) Genome Res , vol.20 , pp. 1180-1190
    • Nissenbaum, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.