The natriuretic peptides BNP and CNP increase heart rate and electrical conduction by stimulating ionic currents in the sinoatrial node and atrial myocardium following activation of guanylyl cyclase-linked natriuretic peptide receptors

Journal of Molecular and Cellular Cardiology

Volumn 52, Issue 5, 2012, Pages 1122-1134

  Springer, Jeremy ^a   Azer, John ^a   Hua, Rui ^a   Robbins, Courtney ^a   Adamczyk, Andrew ^a   McBoyle, Sarah ^a   Bissell, Mary Beth ^a   Rose, Robert A ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Action potential; Electrocardiography; Ion channels; Natriuretic peptide receptors; Natriuretic peptides; Phosphodiesterase; Sinoatrial node

Indexed keywords

BRAIN NATRIURETIC PEPTIDE; GUANYLATE CYCLASE; ISOPRENALINE; MILRINONE; NATRIURETIC PEPTIDE RECEPTOR A; NATRIURETIC PEPTIDE RECEPTOR B; NATRIURETIC PEPTIDE RECEPTOR C; NATRIURETIC PEPTIDE TYPE C;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; ELECTRIC CONDUCTIVITY; ELECTROCARDIOGRAM; GENE EXPRESSION; HEART ATRIUM; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HEART RATE; HYPERPOLARIZATION; IMMUNOCYTOCHEMISTRY; ION CURRENT; ISOLATED HEART; MALE; MOUSE; NONHUMAN; P WAVE; PR INTERVAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RR INTERVAL; SINUS NODE;

ACTION POTENTIALS; ADRENERGIC BETA-AGONISTS; ANIMALS; ATRIAL FUNCTION; ATRIAL NATRIURETIC FACTOR; ELECTRIC CONDUCTIVITY; GUANYLATE CYCLASE; HEART ATRIA; HEART RATE; ISOPROTERENOL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MILRINONE; MYOCYTES, CARDIAC; NATRIURETIC PEPTIDE, BRAIN; NATRIURETIC PEPTIDE, C-TYPE; PATCH-CLAMP TECHNIQUES; PEPTIDE FRAGMENTS; PHOSPHODIESTERASE 3 INHIBITORS; RECEPTORS, ATRIAL NATRIURETIC FACTOR; SINOATRIAL NODE; STIMULATION, CHEMICAL; TETRAHYDROISOQUINOLINES;

MUS;

EID: 84859637397     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2012.01.018     Document Type: Article

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