Preparation and characterization of a novel 3D scaffold from poly(e{open}-caprolactone)/biphasic calcium phosphate hybrid composite microspheres adhesion

Biochemical Engineering Journal

Volumn 64, Issue , 2012, Pages 76-83

  Bao, Trinh Quang ^a   Franco, Rose Ann ^a   Lee, Byong Taek ^a  

^a Soonchunhyang University   (South Korea)

Author keywords

Adhesion; Composite; GF SEDA; In vitro study; PCL BCP HCM 3D scaffold; Porous

Indexed keywords

3D SCAFFOLDS; CAPROLACTONE; EMULSION DROPLETS; GF-SEDA; HOMOGENOUS STRUCTURE; HYBRID COMPOSITES; IN-VITRO; MERCURY POROSIMETERS; MICRO ARCHITECTURES; MICRO-STRUCTURAL; MICROPORES; MTT ASSAYS; OPTIMAL CONDITIONS; POROUS; TISSUE ENGINEERING APPLICATIONS; TOTAL POROSITY; UNIVERSAL TESTING MACHINES; XRD;

ADHESION; CALCIUM PHOSPHATE; CELL ADHESION; CELL CULTURE; COMPOSITE MATERIALS; EMULSIONS; MERCURY (METAL); MICROSPHERES; OPTICAL MICROSCOPY; OPTIMIZATION; THREE DIMENSIONAL;

SCAFFOLDS (BIOLOGY);

CALCIUM PHOSPHATE; POLYCAPROLACTONE;

ARTICLE; CELL ADHESION; CELL GROWTH; CELL INTERACTION; CELL PROLIFERATION; CHEMICAL STRUCTURE; COMPRESSIVE STRENGTH; EMULSION; HYBRIDIZATION; IN VITRO STUDY; MICROPORE FILTER; MICROTECHNOLOGY; POROSITY; PRIORITY JOURNAL;

EID: 84859634042     PISSN: 1369703X     EISSN: 1873295X     Source Type: Journal    
DOI: 10.1016/j.bej.2012.02.005     Document Type: Article

References (32)

1. Chen G., Ushida T., Tateishi T. Scaffold design for tissue engineering. Macromol. Biosci. 2002, 2:67-77.
2. Hollister S.J. Porous scaffold design for tissue engineering. Nat. Mater. 2005, 4:518-524.
3. Hutmacher D.W. Scaffolds in tissue engineering bone and cartilage. Biomaterials 2000, 21:2529-2543.
4. Jones A.C., Arns C.H., Hutmacher D.W., Milthorpe B.K., Sheppard A.P., Knackstedt M.A. The correlation of pore morphology, interconnectivity and physical properties of 3D ceramic scaffolds with bone ingrowth. Biomaterials 2009, 30:1440-1451.
5. Baker S.C., Rohman G., Southgate J., Cameron N.R. The relationship between the mechanical properties and cell behaviour on PLGA and PCL scaffolds for bladder tissue engineering. Biomaterials 2009, 30:1321-1328.
6. Laurencin C.T., Ambrosio A.A., Borden M.D., Cooper J.A. Tissue engineering: orthopaedic applications. Annu. Rev. Biomed. Eng. 1999, 1:19-26.
7. Alessia L., Valentina C., Silvia O., Luigi A., Paolo A.N. PCL microspheres based functional scaffolds by bottom-up approach with predefined microstructural properties and release profiles. Biomaterials 2008, 29:4800-4807.
8. Tabata Y. The importance of drug delivery systems in tissue engineering. Pharm. Sci. Technol. Today 2000, 3:80-89.
9. Wang Y., Liu L., Guo S. Characterization of biodegradable and cytocompatible nano-hydroxyapatite/polycaprolactone porous scaffolds in degradation in vitro. Polym. Degrad. Stab. 2010, 95:207-213.
10. Yoshimoto H., Shin Y.M., Terai H., Vacanti J.P. A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering. Biomaterials 2003, 24:2077-2082.
11. Gross K.A., Rodri'guez-Lorenzo L.M. Biodegradable composite scaffolds with an interconnected spherical network for bone tissue engineering. Biomaterials 2004, 25:4955-4962.
12. Jung Y., Park M.S., Lee J.W., Kim Y.H., Kim S.H., Kim S.H. Cartilage regeneration with highly-elastic three-dimensional scaffolds prepared from biodegradable poly (l-lactide-co-[var epsilon]-caprolactone). Biomaterials 2008, 29:4630-4636.
13. Shum A.W.T., Li J., Mak A.F.T. Fabrication and structural characterization of porous biodegradable poly(dl-lactic-co-glycolic acid) scaffolds with controlled range of pore sizes. Polym. Degrad. Stabil. 2005, 87:487-493.
14. Sun R., Zhang L.F., Du J., Xiong C.D. Preparation and characterization of polylactide/β-tricalciumphosphate scaffolds. Chin. J. Syn. Chem. 2004, 6:536-540.
15. Li F.Z., De J.Y., He C.C., Rui S., Liang X., Zuo C.X., Thirumala G., Cheng D.X. An ionically crosslinked hydrogel containing vancomycin coating on a porous scaffold for drug delivery and cell culture. Int. J. Pharm. 2008, 353:74-87.
16. Ishaug-Riley S.L., Crane-Kruger G.M., Yaszemski M.J., Mikos A.G. Three-dimensional culture of rat calvarial osteoblasts in porous biodegradable polymers. Biomaterials 1998, 19:1405-1412.
17. Murphy W.L., Peters M.C., Kohn D.H., Mooney D.J. Sustained release of vascular endothelial growth factor from mineralized poly(lactide-co-glycolide) scaffolds for tissue engineering. Biomaterials 2000, 21:2521-2527.
18. Elfick A.P.D. Poly(epsilon-caprolactone) as a potential material for a temporary joint spacer. Biomaterials 2002, 23:4463-4467.
19. Daculsi G., Passuti N., Martin S., Deudon C., Legeros R.Z., Raher S. Macroporous calcium phosphate ceramic for long bone surgery in humans and dogs. Clinical and histological study. J. Biomed. Mater. Res. 1990, 24:379-396.
20. Leong K.F., Cheah C.M., Chua C.K. Solid freeform fabrication of three-dimensional scaffolds for engineering replacement tissues and organs. Biomaterials 2003, 24:2363-2378.
21. Petrie Aronin C.E., Cooper J.A., Sefcik L.S., Tholpady S.S., Ogle R.C., Botchwey E.A. Osteogenic differentiation of dura mater stem cells cultured in vitro on three-dimensional porous scaffolds of poly(e{open}-caprolactone) fabricated via co-extrusion and gas foaming. Acta Biomater. 2008, 4:1187-1197.
22. Shor L., Güçeri S., Wen X., Gandhi M., Sun W. Fabrication of three-dimensional polycaprolactone/hydroxyapatite tissue scaffolds and osteoblast-scaffold interactions in vitro. Biomaterials 2007, 28:5291-5297.
23. Lee M.H., Kim H.L., Kim C.H., Lee S.H., Kim J.K., Lee S.J., Park J.C. Effects of low temperature hydrogen peroxide gas on sterilization and cytocompatibility of porous poly(d,l-lactic-co-glycolic acid) scaffolds. Surf. Coat. Technol. 2008, 202:5762-5767.
24. Yingjun W., Xuetao S., Li R., Chunming W., Dong A.W. Porous poly (lactic-co-glycolide) microsphere sintered scaffolds for tissue repair applications. Mater. Sci. Eng. C 2009, 29:2502-2507.
25. Almirall A., Larrecq G., Delgado J.A., Marti'nez S., Planell J.A., Ginebra M.P. Fabrication of low temperature macroporous hydroxyapatite scaffolds by foaming and hydrolysis of an α-TCP paste. Biomaterials 2004, 25:3671-3680.
26. Lee B.T., Youn M.H., Paul R.K., Lee K.H., Song H.Y. In situ synthesis of spherical BCP nanopowders by microwave assisted process. Mater. Chem. Phys. 2007, 104:249-253.
27. Franco R., Nguyen T., et al. Preparation and characterization of electrospun PCL/PLGA membranes and chitosan/gelatin hydrogels for skin bioengineering applications. J. Mater. Sci.: Mater. Med. 2011, 22:2207-2218.
28. Kim H.W., Knowles J.C., Kim H.E. Hydroxyapatite porous scaffold engineered with biological polymer hybrid coating for antibiotic Vancomycin release. J. Mater. Sci.: Mater. Med. 2005, 16:189-195.
29. Bao T.Q., Hiep N.T., Kim Y.H., Yang H.M., Lee B.T. Fabrication and characterization of porous poly(lactic-co-glycolic acid) (PLGA) microspheres for use as a drug delivery system. J. Mater. Sci. 2011, 46:2510-2517.
30. Wu X., Liu Y., Li X., Wen P., Zhang Y., Long Y., Wang X., Guo Y., Xing F., Gao J. Preparation of aligned porous gelatin scaffolds by unidirectional freeze-drying method. Acta Biomater. 2010, 6:1167-1177.
31. Jaklenec A., Wan E., Murray M.E., Mathiowitz E. Novel scaffolds fabricated from protein-loaded microspheres for tissue engineering. Biomaterials 2008, 29:185-192.
32. Salerno A., Guarnieri D., Iannone M., Zeppetelli S., Maio E.D., Iannace S., Netti P.A. Engineered μ-bimodal poly(e{open}-caprolactone) porous scaffold for enhanced hMSC colonization and proliferation. Acta Biomater. 2009, 5:1082-1093.