Osteogenic differentiation of dura mater stem cells cultured in vitro on three-dimensional porous scaffolds of poly(ε-caprolactone) fabricated via co-extrusion and gas foaming

Acta Biomaterialia

Volumn 4, Issue 5, 2008, Pages 1187-1197

  Petrie Aronin, C E ^a   Cooper Jr , J A ^b   Sefcik, L S ^a   Tholpady, S S ^a   Ogle, R C ^a   Botchwey, E A ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Bioreactor culture; Dura; Gas foaming; Polycaprolactone; Polymer blend

Indexed keywords

BIOREACTORS; BRAIN; COMPUTERIZED TOMOGRAPHY; EXTRUSION; MINERALOGY; PHOSPHATASES; POLYCAPROLACTONE; POLYMER BLENDS; SCAFFOLDS (BIOLOGY); SINTERING; SIZE DISTRIBUTION; STEM CELLS;

BIOREACTOR CULTURES; DURA; DURA MATER; IN-VITRO; MINERALISATION; OSTEOGENIC DIFFERENTIATION; POLY(Ε CAPROLACTONE); PORE-SIZE DISTRIBUTION; STEM-CELL; THREE-DIMENSIONAL POROUS SCAFFOLDS;

PORE SIZE;

ALKALINE PHOSPHATASE; POLYCAPROLACTONE; POLYMER;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOREACTOR; BONE MINERALIZATION; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CERAMICS; CONTROLLED STUDY; CULTURE MEDIUM; DURA MATER; FETUS; FOAMING; GAS; HISTOCHEMISTRY; IN VITRO STUDY; MICRO-COMPUTED TOMOGRAPHY; MOLECULAR DYNAMICS; NONHUMAN; OSTEOBLAST; PARTICLE SIZE; POROSITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STEM CELL; TEMPERATURE; TIME;

EID: 48449105146     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2008.02.029     Document Type: Article

References (53)

1. Prolo D.J., and Rodrigo J.J. Contemporary bone graft physiology and surgery. Clin Orthop 200 (1985) 322-342
2. Damien C.J., and Parsons J.R. Bone graft and bone graft substitutes: a review of current technology and applications. J Appl Biomater 2 (1991) 187-208
3. Lane J.M., Tomin E., and Bostrom M.P.G. Biosynthetic bone grafting. Clin Orthop Relat Res 367S (1999) 107-117
4. Arrington E.D., Smith W.J., Chambers H.G., Bucknell A.L., and Davino N.A. Complications of iliac crest bone graft harvesting. Clin Orthop 329 (1996) 300-309
5. Vercaigne S., Wolke J.G.C., Naert I., and Jansen J.A. The effect of titanium plasma-sprayed implants on trabecular bone healing in the goat. Biomaterials 19 11-12 (1998) 1093-1099
6. Eppley B.L., Morales L., Wood R., Pensler J., Goldstein J., Havlik R.J., et al. Resorbable PLLA-PGA plate and screw fixation in pediatric craniofacial surgery: clinical experience in 1883 patients. Plast Reconstr Surg 114 4 (2004) 850-856
7. Muller K., and Valentine-Thon E. Hypersensitivity to titanium: clinical and laboratory evidence. Neuroendocr Lett S27 (2006) 31-35
8. Wan Z.N., Dorr L.D., Woodstone T., Ranawat A., and Song M. Effect of stem stiffness and bone stiffness on bone remodeling in cemented total hip replacement. J Arthroplast 14 2 (1999) 149-158
9. Hobar P.C., Masson J.A., Wilson R., and Zerwekh J. The importance of the dura in craniofacial surgery. Plast Reconstr Surg 98 2 (1996) 217-225
10. Drake D.B., Persing J.A., Berman D.E., and Ogle R.C. Calvarial deformity regeneration following subtotal craniectomy for craniosynostosis: a case report and theoretical implications. J Craniofac Surg 4 2 (1993) 85-89 discussion 90
11. Ogle R.C., Tholpady S., McGlynn K.A., and Ogle R.A. Regulation of cranial suture morphogenesis. Cells Tissues Organs 176 1-3 (2004) 54-66
12. Opperman L.A., Sweeney T.M., Redmon J., Persing J.A., and Ogle R.C. Tissue interactions with underlying dura mater inhibit osseous obliteration of developing cranial sutures. Dev Dynam 198 4 (1993) 312-322
13. Laurencin C.T., Attawia M.A., Elgendy H.E., and Herbert K.M. Tissue engineered bone-regeneration using degradable polymers: the formation of mineralized matrices. Bone 19 (1996) 93S-99S
14. Ishaug-Riley S.L., Crane-Kruger G.M., Yaszemski M.J., and Mikos A.G. Three-dimensional culture of rat calvarial osteoblasts in porous biodegradable polymers. Biomaterials 19 (1998) 1405-1412
15. Borden M., Attawia M., Khan Y., and El-Amin S.F. Tissue-engineered bone formation in vivo using a novel sintered polymeric microsphere matrix. J Bone Joint Surg Br 86B 8 (2004) 1200-1208
16. Coombes A.D., and Heckman J.D. Gel casting of resorbable polymers. Biomaterials 13 (1992) 217-224
17. Zhang R., and Ma P.X. Porous poly(l-lactic acid)/apatite composites created by biomimetic process. J Biomed Mater Res 45 (1999) 285-293
18. Park A., Wu B., and Griffith L.G. Integration of surface modification and 3D fabrication techniques to prepared patterned poly-(l-lactide) substrates allowing regionally selective cell adhesion. J Biomater Sci Polym Ed 9 (1998) 89-110
19. Hutmacher D.W., Schantz T., Zein I., Ng K.W., Teoh S.H., and Tan K.C. Mechanical properties and cell cultural response of polycaprolactone scaffolds designed and fabricated via fused deposition modeling. J Biomed Mater Res 55 (2001) 203-216
20. Reignier J., and Huneault M.A. Preparation of interconnected poly(3-caprolactone) porous scaffolds by a combination of polymer and salt particulate leaching. Polymer 47 (2006) 4703-4717
21. Washburn N.R., Simon C.G., Tona A., Elgendy H.M., Karim A., and Amis E.J. Co-extrusion of biocompatible polymers for scaffolds with co-continuous morphology. J Biomed Mater Res 60 1 (2002) 20-29
22. Cheung H.Y., Lau K.T., Lu T.P., and Hui D. A critical review on polymer-based bio-engineered materials for scaffold development. Composites 38B (2007) 291-300
23. Zhou Y., Hutmacher D.W., Varawan S.L., and Lim T.M. In vitro bone engineering based on polycaprolactone and polycaprolactone-tricalcium phosphate composites. Polym Int 56 (2007) 333-342
24. Endres M., Hutmacher D.W., Salgado A.J., Kaps C., Ringe J., Reis R.L., et al. Osteogenic induction of human bone marrow-derived mesenchymal progenitor cells in novel synthetic polymer-hydrogel matrices. Tissue Eng 9 4 (2003) 689-702
25. Schantz J.T., Hutmacher D.W., Lam C.X.F., Brinkmann M., Wong K.M., Lim T.C., et al. Repair of calvarial defects with customized tissue-engineered bone grafts - II. Evaluation of cellular efficiency and efficacy in vivo. Tissue Eng 9 (2003) S127-S139
26. Xu Y., Malladi P., Wagner D.R., and Longaker M.T. Adipose-derived mesenchymal cells as a potential cell source for skeletal regeneration. Curr Opin Mol Ther 7 4 (2005) 300-305 [Review]
27. Hee C.K., Jonikas M.A., and Nicoll S.B. Influence of three-dimensional scaffold on the expression of osteogenic differentiation markers by human dermal fibroblasts. Biomaterials 27 6 (2006) 875-884
28. Li C.D., Zhang W.Y., Li H.L., Jiang X.X., Tang P., and Mao N. Isolation and identification of a multilineage potential mesenchymal cell from human placenta. Placenta (2005) [September 17 Epub]
29. Roostaeian J., Carlsen B., Simhaee D., Jarrahy R., Huang W., Ishida K., et al. Characterization of growth and osteogenic differentiation of rabbit bone marrow stromal cells. J Surg Res 133 2 (2006) 76-83
30. Ikeda E., Hirose M., Kotobuki N., Shimaoka H., Tadokoro M., Maeda M., et al. Osteogenic differentiation of human dental papilla mesenchymal cells. Biochem Biophys Res Commun 342 4 (2006) 1257-1262
31. Tholpady SS, McGlynn KA, Ogle RA, Ogle RC. Multipotent stem cells from dura mater. Am Soc Cell Biol 2003 [San Francisco, CA Abstract #641].
32. Petrie Aronin C.E., Tholpady S.S., Ogle R.C., and Botchwey E.A. Proliferative capacity and osteogenic potential of novel dura mater stem cells on poly-lactic-co-glycolic acid (PLGA). J Biomed Mater Res (2007) [Epub]
33. Petrie Aronin C.E., Sadik K.W., Lay A.L., Rion D.B., Tholpady S.S., Ogle R.C., et al. Comparative effects of scaffold pore size, pore volume, and total void volume on cranial bone healing patterns using microsphere-based scaffolds. J Biomed Mater Res (2007) [In review]
34. Yamada K., Miyamoto S., Nagata I., Kikuchi H., Ikada Y., Iwata H., et al. Development of a dural substitute from synthetic bioabsorbable polymers. J Neurosurg 86 (1997) 1012-1017
35. NIH Publication #85-23 Rev; 1985.
36. Botchwey E.A., Pollack S.R., Levine E.M., Johnston E.D., and Laurencin C.T. Quantitative analysis of three-dimensional fluid flow in rotating bioreactors for tissue engineering. JBMR Pt A 69 2 (2004) 205-215
37. Botchwey E.A., Pollack S.R., Levine E.M., and Laurencin C.T. Bone tissue engineering in a rotating bioreactor using a microcarrier matrix system. J Biomed Mater Res 55 2 (2001) 242-253
38. Karageorgiou V., and Kaplan D. Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials 26 (2005) 5474-5491
39. Hulbert S.F., Young F.A., Mathews R.S., Klawitter J.J., Talbert C.D., and Stelling F.H. Potential of ceramic materials as permanently implantable skeletal prostheses. J Biomed Mater Res 4 3 (1970) 433-456
40. Kuboki Y., Jin Q., and Takita H. Geometry of carriers controlling phenotypic expression in BMP-induced osteogenesis and chondrogenesis. J Bone Joint Surg Am 83A Suppl. 1 Pt 2 (2001) S105-S115
41. Tsuruga E., Takita H., Itoh H., Wakisaka Y., and Kuboki Y. Pore size of porous hydroxyapatite as the cell-substratum controls BMP-induced osteogenesis. J Biochem (Tokyo) 121 2 (1997) 317-324
42. Ayers R.A., Simske S.J., Bateman T.A., Petkus A., Sachdeva R.L., and Gyunter V.E. Effect of nitinol implant porosity on cranial bone ingrowth and apposition after 6 weeks. J Biomed Mater Res 45 1 (1999) 42-47
43. Pham Q.P., Sharma U., and Mikos A.G. Electrospun poly(epsilon-caprolactone) microfiber and multilayer nanofiber/microfiber scaffolds: characterization of scaffolds and measurements of cellular infiltration. Biomacromolecules 7 (2006) 2796-2805
44. Whang K., Healy K.E., Elenz D.R., Nam E.K., Tsai D.C., Thomas C.H., et al. Engineering bone regeneration with bioabsorbable scaffolds with novel microarchitecture. Tissue Eng 5 1 (1999) 35-51
45. Lin-Gibson S., Cooper J.A., Landis F.A., and Cicerone M.T. Systemic investigation of porogen size and content on scaffold morphometric parameters and properties. Biomacromolecules 8 5 (2007) 1511-1518
46. Detamore M.S., and Athanasiou K.A. Use of a rotating bioreactor toward tissue engineering the temporomandibular joint disc. Tissue Eng 11 7-8 (2005) 1188-1197
47. Lian J.B., and Stein G.S. Development of the osteoblast phenotype: molecular mechanisms mediating osteoblast growth and differentiation. Iowa Orthop J 15 (1995) 118-140
48. Alvarez-Barreto J.F., Linehan S.M., Shambaugh R.L., and Sikavitsas V.I. Flow perfusion improves seeding of tissue engineering scaffolds with different architectures. Ann Biomed Eng 35 3 (2007) 429-442
49. Datta N., Pham Q.P., Sharma U., Sikavitsas V.I., Jansen J.A., and Mikos A.G. In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation. Proc Natl Acad Sci USA 103 8 (2006) 2488-2493
50. Yu X., Botchwey E.A., Levine E.M., Pollack S.R., and Laurencin C.T. Bioreactor-based bone tissue engineering: the influence of dynamic flow on osteoblast phenotypic expression and matrix mineralization. Proc Natl Acad Sci USA 101 (2004) 11203-11208
51. Wu L.B., and Ding J.D. In vitro degradation of three-dimensional porous poly(d,l-lactide-co-glycolide) scaffolds for tissue engineering. Biomaterials 25 27 (2004) 5821-5830
52. Shin M, Yoshimoto H, Vacanti JP. In vivo bone tissue engineering using mesenchymal stem cells on a novel electrospun nanofibrous scaffold. Tissue Eng 2004;10(1-2):33-41.
53. Chastain S.R., Kundu A.K., Dhar S., Calvert J.W., and Putnam A.J. Adhesion of mesenchymal stem cells to polymer scaffolds occurs via distinct ECM ligands and controls their osteogenic differentiation. J Biomed Mater Res A 78 1 (2006) 73-85