The application of a crosslinked pectin-based wafer matrix for gradual buccal drug delivery

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 100 B, Issue 4, 2012, Pages 1029-1043

  Shaikh, Rubina P ^a   Pillay, Viness ^a   Choonara, Yahya E ^a   Toit, Lisa C Du ^a   Ndesendo, Valence M K ^a   Kumar, Pradeep ^a   Khan, Riaz A ^b  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b QASSIM UNIVERSITY   (Saudi Arabia)

Author keywords

buccal drug delivery; crosslinked mucoadhesive polymers; lyophilization; molecular mechanics simulations; porositometry; wafer matrix

Indexed keywords

BUCCAL DRUG DELIVERY; CROSSLINKED; LYOPHILIZATION; MOLECULAR MECHANICS SIMULATIONS; POROSITOMETRY;

CALCIUM CHLORIDE; DRUG PRODUCTS; MOLECULAR MECHANICS;

MATRIX ALGEBRA;

ANTIHISTAMINIC AGENT; CROSS LINKING REAGENT; DIPHENHYDRAMINE; PECTIN WAFER MATRIX; UNCLASSIFIED DRUG;

ARTICLE; BUCCAL DRUG ADMINISTRATION; COMPUTER MODEL; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SOLUBILITY; FREEZE DRYING; IN VITRO STUDY; MOLECULAR MECHANICS; MORPHOLOGY; POROSITY; QUANTITATIVE ANALYSIS; SIMULATION; SYNTHESIS;

ADMINISTRATION, BUCCAL; BIOCOMPATIBLE MATERIALS; CATIONS; COMPUTER SIMULATION; CROSS-LINKING REAGENTS; DRUG DELIVERY SYSTEMS; DRUG DESIGN; FREEZE DRYING; HOT TEMPERATURE; HUMANS; OLIGOSACCHARIDES; PECTINS; POLYMERS; POROSITY; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE;

EID: 84859617754     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.32668     Document Type: Article

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