Preparation and solid-state characterization of bupivacaine hydrochloride cyclodextrin complexes aimed for buccal delivery

Journal of Pharmaceutical and Biomedical Analysis

Volumn 52, Issue 1, 2010, Pages 9-18

  Jug, Mario ^a   Maestrelli, Francesca ^b   Bragagni, Marco ^b   Mura, Paola ^b  

^a UNIVERSITY OF ZAGREB   (Croatia)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

cyclodextrin; Buccal delivery; Bupivacaine hydrochloride; Solid state analysis; Soluble cyclodextrin epichlorohydrin polymer

Indexed keywords

BETA CYCLODEXTRIN; BUPIVACAINE; EPICHLOROHYDRIN; SALIVA SUBSTITUTE;

ARTICLE; CHEEK MUCOSA; CHEMICAL INTERACTION; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SOLUBILITY; DRUG SYNTHESIS; EVAPORATION; FREEZE DRYING; IN VITRO STUDY; INFRARED SPECTROSCOPY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SOLID STATE; X RAY POWDER DIFFRACTION;

ADMINISTRATION, BUCCAL; ANESTHETICS, LOCAL; BETA-CYCLODEXTRINS; BUPIVACAINE; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CRYSTALLOGRAPHY, X-RAY; DOSAGE FORMS; DRUG CARRIERS; DRUG COMPOUNDING; EPICHLOROHYDRIN; FREEZE DRYING; KINETICS; MICROSCOPY, ELECTRON, SCANNING; POLYMERS; POWDER DIFFRACTION; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TECHNOLOGY, PHARMACEUTICAL; VOLATILIZATION;

EID: 74249099267     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.11.013     Document Type: Article

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