In vivo antitumor effects of 4,7-dimethoxy-5-methyl-1,3-benzodioxole isolated from the fruiting body of Antrodia camphorata through activation of the p53-mediated p27/Kip1 signaling pathway

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 14, 2012, Pages 3612-3618

  Tu, Shih Hsin ^a,b   Wu, Chih Hsiung ^a,c,d   Chen, Li Ching ^a   Huang, Ching Shui ^a,b   Chang, Hui Wen ^e   Chang, Chien Hsi ^e   Lien, Hsiu Man ^f,g   Ho, Yuan Soon ^a,e  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b CATHAY GENERAL HOSPITAL   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^f TUNGHAI UNIVERSITY   (Taiwan)

^g Yusheng Biotechnology Co Ltd   (Taiwan)

Author keywords

antitumor; Antrodia camphorate; COLO 205; p27 Kip1; p53

Indexed keywords

ANTI-TUMORS; ANTRODIA CAMPHORATE; COLO 205; P27/KIP1; P53;

ANTHROPOMETRY; BIOLOGICAL MATERIALS; CHEMOTHERAPY; PROTEINS; TUMORS;

DRUG PRODUCTS;

1,3 BENZODIOXOLE DERIVATIVE; 4,7 DIMETHOXY 5 METHYL 1,3 BENZODIOXOLE; 4,7-DIMETHOXY-5-METHYL-1,3-BENZODIOXOLE; ANTINEOPLASTIC AGENT; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; PROTEIN P53;

ANIMAL; ANTRODIA; ARTICLE; CANCER TRANSPLANTATION; CELL PROLIFERATION; CHEMISTRY; COLON TUMOR; DRUG EFFECT; DRUG SCREENING; FRUITING BODY; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MOUSE; NUDE MOUSE; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTRODIA; BENZODIOXOLES; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; FRUITING BODIES, FUNGAL; HUMANS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; XENOGRAFT MODEL ANTITUMOR ASSAYS;

ANTRODIA; BASIDIOMYCOTA; CINNAMOMUM KANEHIRAI; LAURACEAE; MUS MUSCULUS; TAIWANOFUNGUS CAMPHORATUS;

EID: 84859597743     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf300221g     Document Type: Article

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