AAV vectors transduce hepatocytes in vivo as efficiently in cirrhotic as in healthy rat livers

Gene Therapy

Volumn 19, Issue 4, 2012, Pages 411-417

  Sobrevals, L ^a,c   Enguita, M ^a   Rodriguez, C ^a,b   Gonzalez Rojas, J ^a   Alzaguren, P ^a   Razquin, N ^a   Prieto, J ^a,b   Fortes, P ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY OF NAVARRA   (Spain)

^c CENTRE FOR GENOMIC REGULATION CRG   (Spain)

Author keywords

CCl 4; liver cirrhosis; luciferase expression; recombinant AAV vector; TAA

Indexed keywords

ADENO ASSOCIATED VIRUS 1 ENCODING LUCIFERASE; ADENO ASSOCIATED VIRUS SEROTYPE 1; PARVOVIRUS VECTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENOME; HEPATIC ARTERY; IN VIVO STUDY; LIVER CELL; LIVER CIRRHOSIS; LIVER RESECTION; MALE; NONHUMAN; PORTAL VEIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; DEPENDOVIRUS; GENE THERAPY; GENETIC VECTORS; HEPATIC ARTERY; HEPATOCYTES; LIVER; LIVER CIRRHOSIS; LIVER REGENERATION; LUCIFERASES; MALE; PORTAL VEIN; RATS; RATS, SPRAGUE-DAWLEY; TRANSDUCTION, GENETIC;

ADENO-ASSOCIATED VIRUS; RATTUS;

EID: 84859589413     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2011.119     Document Type: Article

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