Fibroblast Growth Factor Receptor 3 (FGFR3) is a strong Heat shock protein 90 (Hsp90) client: Implications for therapeutic manipulation

Journal of Biological Chemistry

Volumn 286, Issue 22, 2011, Pages 19597-19604

  Laederich, Melanie B ^a,b   Degnin, Catherine R ^a   Lunstrum, Gregory P ^a   Holden, Paul ^a,b   Horton, William A ^a,b  

^a SHRINERS HOSPITAL FOR CHILDREN   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTORS; GELDANAMYCIN; GENETIC DISEASE; HEAT SHOCK PROTEIN; KEY REGULATORS; MOLECULAR CHAPERONES; UBIQUITIN LIGASES; UBIQUITINATION;

FIBROBLASTS; PEPTIDES;

CELL CULTURE;

CELL CYCLE PROTEIN 37; CHAPERONE; FIBROBLAST GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 3; HEAT SHOCK PROTEIN 90; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; UBIQUITINATION;

ACHONDROPLASIA; ANIMALS; BENZOQUINONES; CELL CYCLE PROTEINS; CERCOPITHECUS AETHIOPS; CHAPERONINS; COS CELLS; ENZYME STABILITY; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; MICE; MOLECULAR CHAPERONES; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 3; UBIQUITINATION;

EID: 79957593454     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.206151     Document Type: Article

References (53)

1. Eswarakumar, V. P., Lax, I., and Schlessinger, J. (2005) Cytokine Growth Factor Rev. 16, 139-149
2. Knights, V., and Cook, S. J. (2010) Pharmacol. Ther 125, 105-117
3. Ornitz, D. M. (2005) Cytokine Growth Factor Rev. 16, 205-213
4. Cappellen, D., De Oliveira, C., Ricol, D., de Medina, S., Bourdin, J., Sastre-Garau, X., Chopin, D., Thiery, J. P., and Radvanyi, F. (1999) Nat. Genet. 23, 18-20
5. Chesi, M., Nardini, E., Brents, L. A., Schröck, E., Ried, T., Kuehl, W. M., and Bergsagel, P. L. (1997) Nat. Genet. 16, 260-264
6. Laederich, M. B., and Horton, W. A. (2010) Curr. Opin. Pediatr. 22, 516-523
7. Borkovich, K. A., Farrelly, F. W., Finkelstein, D. B., Taulien, J., and Lindquist, S. (1989) Mol. Cell. Biol. 9, 3919-3930
8. Taipale, M., Jarosz, D. F., and Lindquist, S. (2010) Nat. Rev. Mol. Cell Biol. 11, 515-528
9. Theodoraki, M. A., Kunjappu, M., Sternberg, D. W., and Caplan, A. J. (2007) Exp. Cell Res. 313, 3851-3858
10. Xu, W., Yuan, X., Xiang, Z., Mimnaugh, E., Marcu, M., and Neckers, L. (2005) Nat. Struct. Mol. Biol. 12, 120-126
11. da Rocha Dias, S., Friedlos, F., Light, Y., Springer, C., Workman, P., and Marais, R. (2005) Cancer Res. 65, 10686-10691
12. Shimamura, T., Lowell, A. M., Engelman, J. A., and Shapiro, G. I. (2005) Cancer Res. 65, 6401-6408
13. Murata, S., Chiba, T., and Tanaka, K. (2003) Int. J. Biochem. Cell Biol. 35, 572-578
14. Kim, Y. S., Alarcon, S. V., Lee, S., Lee, M. J., Giaccone, G., Neckers, L., and Trepel, J. B. (2009) Curr. Top Med. Chem. 9, 1479-1492
15. Kamal, A., Boehm, M. F., and Burrows, F. J. (2004) Trends Mol. Med. 10, 283-290
16. Waza, M., Adachi, H., Katsuno, M., Minamiyama, M., Sang, C., Tanaka, F., Inukai, A., Doyu, M., and Sobue, G. (2005) Nat. Med. 11, 1088-1095
17. Adachi, H., Waza, M., Tokui, K., Katsuno, M., Minamiyama, M., Tanaka, F., Doyu, M., and Sobue, G. (2007) J. Neurosci. 27, 5115-5126
18. Chen, H., Ma, J., Li, W., Eliseenkova, A. V., Xu, C., Neubert, T. A., Miller, W. T., and Mohammadi, M. (2007) Mol. Cell 27, 717-730
19. Cho, J. Y., Guo, C., Torello, M., Lunstrum, G. P., Iwata, T., Deng, C., and Horton, W. A. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 609-614
20. Chiosis, G., Huezo, H., Rosen, N., Mimnaugh, E., Whitesell, L., and Neckers, L. (2003) Mol. Cancer Ther. 2, 123-129
21. Sweeney, C., Fambrough, D., Huard, C., Diamonti, A. J., Lander, E. S., Cantley, L. C., and Carraway, K. L., 3rd. (2001) J. Biol. Chem. 276, 22685-22698
22. VanSlyke, J. K., and Musil, L. S. (2000) Methods 20, 156-164
23. Avantaggiati, M. L., Carbone, M., Graessmann, A., Nakatani, Y., Howard, B., and Levine, A. S. (1996) EMBO J. 15, 2236-2248
24. Guo, C., Degnin, C. R., Laederich, M. B., Lunstrum, G. P., Holden, P., Bihlmaier, J., Krakow, D., Cho, Y. J., and Horton, W. A. (2008) Cell Signal 20, 1471-1477
25. Tavormina, P. L., Shiang, R., Thompson, L. M., Zhu, Y. Z., Wilkin, D. J., Lachman, R. S., Wilcox, W. R., Rimoin, D. L., Cohn, D. H., and Wasmuth, J. J. (1995) Nat. Genet. 9, 321-328
26. Monsonego-Ornan, E., Adar, R., Rom, E., and Yayon, A. (2002) FEBS Lett. 528, 83-89
27. Lievens, P. M., Roncador, A., and Liboi, E. (2006) J. Mol. Biol. 357, 783-792
28. Bernard-Pierrot, I., Brams, A., Dunois-Lardé, C., Caillault, A., Diez de Medina, S. G., Cappellen, D., Graff, G., Thiery, J. P., Chopin, D., Ricol, D., and Radvanyi, F. (2006) Carcinogenesis 27, 740-747
29. Germano, S., Barberis, D., Santoro, M. M., Penengo, L., Citri, A., Yarden, Y., and Gaudino, G. (2006) J. Biol. Chem. 281, 21710-21719
30. Xu, W., Mimnaugh, E., Rosser, M. F., Nicchitta, C., Marcu, M., Yarden, Y., and Neckers, L. (2001) J. Biol. Chem. 276, 3702-3708
31. Schulte, T. W., Akinaga, S., Soga, S., Sullivan, W., Stensgard, B., Toft, D., and Neckers, L. M. (1998) Cell Stress Chaperones 3, 100-108
32. Schulte, T. W., and Neckers, L. M. (1998) Cancer Chemother Pharmacol 42, 273-279
33. Jeong, J. H., An, J. Y., Kwon, Y. T., Li, L. Y., and Lee, Y. J. (2008) J. Cell. Biochem. 105, 585-595
34. Zhang, T., Li, Y., Yu, Y., Zou, P., Jiang, Y., and Sun, D. (2009) J. Biol. Chem. 284, 35381-35389
35. Citri, A., Harari, D., Shohat, G., Ramakrishnan, P., Gan, J., Lavi, S., Eisenstein, M., Kimchi, A., Wallach, D., Pietrokovski, S., and Yarden, Y. (2006) J. Biol. Chem. 281, 14361-14369
36. Gould, C. M., Kannan, N., Taylor, S. S., and Newton, A. C. (2009) J. Biol. Chem. 284, 4921-4935
37. Hikri, E., Shpungin, S., and Nir, U. (2009) Cell Signal 21, 588-596
38. Margineantu, D. H., Emerson, C. B., Diaz, D., and Hockenbery, D. M. (2007) PLoS. One 2, e1066
39. Sun, X., Barlow, E. A., Ma, S., Hagemeier, S. R., Duellman, S. J., Burgess, R. R., Tellam, J., Khanna, R., and Kenney, S. C. (2010) Proc. Natl. Acad. Sci. U.S.A. 107, 3146-3151
40. Joazeiro, C. A., Wing, S. S., Huang, H., Leverson, J. D., Hunter, T., and Liu, Y. C. (1999) Science 286, 309-312
41. Zhou, P., Fernandes, N., Dodge, I. L., Reddi, A. L., Rao, N., Safran, H., DiPetrillo, T. A., Wazer, D. E., Band, V., and Band, H. (2003) J. Biol. Chem. 278, 13829-13837
42. Morishima, Y., Wang, A. M., Yu, Z., Pratt, W. B., Osawa, Y., and Lieberman, A. P. (2008) Hum. Mol. Genet. 17, 3942-3952
43. Xu, W., Marcu, M., Yuan, X., Mimnaugh, E., Patterson, C., and Neckers, L. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 12847-12852
44. Qing, J., Du, X., Chen, Y., Chan, P., Li, H., Wu, P., Marsters, S., Stawicki, S., Tien, J., Totpal, K., Ross, S., Stinson, S., Dornan, D., French, D., Wang, Q. R., Stephan, J. P., Wu, Y., Wiesmann, C., and Ashkenazi, A. (2009) J. Clin. Invest. 119, 1216-1229
45. Krejci, P., Bryja, V., Pachernik, J., Hampl, A., Pogue, R., Mekikian, P., and Wilcox, W. R. (2004) Exp. Cell Res. 297, 152-164
46. Citri, A., Gan, J., Mosesson, Y., Vereb, G., Szollosi, J., and Yarden, Y. (2004) EMBO Rep 5, 1165-1170
47. Li, R., Soosairajah, J., Harari, D., Citri, A., Price, J., Ng, H. L., Morton, C. J., Parker, M. W., Yarden, Y., and Bernard, O. (2006) FASEB J. 20, 1218-1220
48. Prince, T., and Matts, R. L. (2004) J. Biol. Chem. 279, 39975-39981
49. Bae, J. H., Boggon, T. J., Tomé, F., Mandiyan, V., Lax, I., and Schlessinger, J. (2010) Proc. Natl. Acad. Sci. U.S.A. 107, 2866-2871
50. Okiyoneda, T., Barrière, H., Bagdány, M., Rabeh, W. M., Du, K., Höhfeld, J., Young, J. C., and Lukacs, G. L. (2010) Science 329, 805-810
51. Vecchione, A., Cooper, H. J., Trim, K. J., Akbarzadeh, S., Heath, J. K., and Wheldon, L. M. (2007) Proteomics 7, 4565-4578
52. Terry, J., Lubieniecka, J. M., Kwan, W., Liu, S., and Nielsen, T. O. (2005) Clin Cancer Res. 11, 5631-5638
53. Nakashima, T., Ishii, T., Tagaya, H., Seike, T., Nakagawa, H., Kanda, Y., Akinaga, S., Soga, S., and Shiotsu, Y. (2010) Clin. Cancer Res. 16, 2792-2802